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Schwann in Medical News

Grant for brain tumor and deafness research

...lled merlin, which in turn cause cancers in a range of cell types including schwann cells in the nervous system. schwann cells produce the sheaths that surround and insulate neurons. Although t...

Mayo researchers discover mechanism of cell type-specific signaling in tumor development

...he researchers found, controls the tumor suppressor gene Merlin. When Merlin is absent or mutated, the result is schwannoma, a form of tumor involving schwann cells which make up the myelin sheath that covers nerves. Merlin has also been shown to play a part in causing melanoma, mesothelioma and possibly col...

2008 AAAS Newcomb Cleveland Prize recognizes science paper on limb regeneration in newts

... reported that the protein nAG helps to stimulate the proliferation of the blastema cells. The protein is secreted by both nervous-system cells called schwann cells and epidermal cells near the wound, which helps explain why nerves are required for blastema formation. Even when the nerve was severed beneath ...

Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis

...igger for neurofibroma growth has been a mystery. schwann cells, which form a protective sheath around nerve...romas requires two steps: complete loss of NF1 in schwann cells (rendering them NF1-/-) and an interaction between NF1-/- schwann cells and NF1+/- mast cells. While...

Cancer requires support from immune system to develop, UT Southwestern researchers report

...nclude many different types of cells, particularly schwann cells, which provide a fatty coating that makes ne... in mice that plexiform neurofibromas develop from schwann cells that have two mutated copies of Nf1. In addi...he animals need two mutated copies of Nf1 in their schwann cells to develop neurofibromas, which the rest of ...

Protein key to neuro-regeneration

...s a vital role in the regulating the plasticity of schwann cells which is vital for the way in which the peri...em regenerates and repairs itself after injury. schwann cells produce the sheaths that surround and insula...n there is damage to the peripheral nervous system schwann cells unwrap themselves from the degenerating axon...

Research to lead to brain tumor therapies

...lled merlin, which in turn cause cancers in a range of cell types including schwann cells in the brain. schwann cells produce the sheaths that surround and insulate neurons. Although t...

Protein in human hair shows promise for regenerating nerves

.... They studied how keratin affects the activity of schwann cells, which play a vital role in nerve regenerati...aid Van Dyke. We believe that keratin helps amp up schwann cell activity and give the nerve regeneration proc...e laboratory studies showed that keratin activated schwann cells and increased their proliferation and migrat...

Transplanted Bone Marrow Cells Aid Nerve Regeneration

...sult that rates of cell differentiation and regeneration would improve." After 24 weeks, the BMCs differentiated into cells with characteristics of schwann cells -- a type of neural cell that provides the insulating myelin around the axons of peripheral nerve cells. "The differentiated cells ... contri...

Bone marrow cell transplants help nerve regeneration

..., the BMCs after 24 weeks differentiated into cells with characteristics of schwann cells a variety of neural cell that provides the insulating myelin around ...stumps, with healthier vascularity. The differentiated cells, similar to schwann cells, contributed significantly to the promotion of axon regeneration thro...
Schwann in Medical Dictionary

Spinal tumor

...ells within or near the spine. ... A form of spinal tumor involving the schwann cells is called a Schwannoma. ... Spinal tumors can occur inside th...ells within or near the spine. ... A form of spinal tumor involving the schwann cells is called a Schwannoma. ... A Patient's Guide to Spinal Tumors...
Schwann in Biological News

Turning back the clock for Schwann cells

Myelin-making Schwann cells have an ability every aging Hollywood star would envy: they can become young again. According to a study appearing in the May 19 issue of the Journal of Cell Biology , David B. Parkinson (University College London, London, UK) and collogues have pinned down a protein t...

Peripheral nerve repair with fat precursor cells led to wider nerves and less muscle atrophy

...ps. Pre-clinical studies have shown that including schwann cells within nerve conduits can enhance nerve regeneration. However, the incorporation of schwann cells requires a second surgery, renders a secondary nerve nonfunctional, and requires schwann cells in high numbers that are clinically challeng...

Protein identified as critical to insulating the body's wiring could also become treatment target

...rvous system that controls arms and legs, the protein erbin regulates the protein neuregulin 1, stabilizing and interacting with the ErbB2 receptor on schwann cells so they can make myelin, which insulates the wiring. Their studies in mice have shown that when erbin is missing or mutated, the insulation i...

Spun-sugar fibers spawn sweet technique for nerve repair

...e polymer remained. The researchers then grew nerve-insulating cells called schwann cells on these polymer tubes. These cells automatically aligned lengthwise along the tubes, as did nerve cells grown on top of the schwann cells. This alignment is critical for the fast growth of nerves, Shi sai...

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord

...studies have reported that MSCs have differentiated into neuronal cells and schwann cells as well as fat cells and bone cells. Our study showed that direct, in...results contrast with previously published reports that demonstrated robust schwann cell remyelination after bone marrow stromal cell injection," reported Dr. ...

Rutgers scientist's research reveals critical knowledge about the nervous system

... those links. Specifically, her work focuses on schwann cells within the peripheral nervous system and the...ll phone that loses its signal. Determining how schwann cells and axons communicate with one another could...ne unique aspect of the communication link between schwann cells and axons is that they are mutually dependen...

Researchers discover gene crucial for nerve cell insulation

...searchers did not fully understand the complex genetic process that enables schwann cells, found in the peripheral nervous system, to coat nerves with myelin. ...n said. Ultimately, the sequence of activating genes "switches on" the schwann cell, which wraps the nerve axon, the arm-like projection that conveys nerv...

Stem cells found in adult skin can be transplanted and function in mouse models of disease

... efficiently generate a type of glial cell, called schwann cells, that can myelinate demyelinated axons (part...that we can efficiently generate and isolate these schwann cells from SKPs raises the possibility that we could treat humans with schwann cells derived from human skin stem cells, and perh...

Scientists discover the molecular switch for nerve cells' insulating jelly rolls

...uregulin as the myelin signal. This signal directs schwann cells, the nervous system's cellular architects, t...yonic mice into laboratory dishes. They then added schwann cells to the dishes. They observed that the schwann cells sat on the axons and did not produce any mye...
Schwann in Biological Technology

UCF team's advanced nerve cell system could help cure diabetic neuropathy, related diseases

...ems associated with diabetic neuropathy originate, schwann cells perform this function. Due to the fam...ects of a drug. Past research aimed at getting schwann cells to myelinate motor nerves, or motoneurons, h... be achievable. Even without that advance, the schwann cell myelination model could reveal new drug treat...
Schwann in Biological Definition

Axon

...onger. In vertebrates generally, the axons of many neurons are sheathed in myelin , which is formed by either of two types of glial cells : schwann cells ensheathing peripheral neurons and oligodendrocytes insulating those of the central nervous system . Along myelinated nerve fibers, gaps ...

Neuron

... their action potentials to travel faster than in unmyelinated axons of the same diameter. Formed by glial cells in the central nervous system and schwann cells in the peripheral nervous system. The myelin sheath in peripheral nerves normally runs along the axon in sections about 1 mm long, punctuated by...
Schwann in Biological Dictionary

Schwann cells

... Named after the German physiologist Theodor schwann , schwann cells are a variety of glial cell that keep...ipheral nerve fibres alive. In myelinated axons, schwann cells form the myelin sheath (see below). The...

Peripheral protein

...22 is produced primarily by specialized cells called ... The buildup of unprocessed peripheral myelin protein 22 probably also disrupts ... schwann cells are part of the peripheral nervous system that connects the brain ... myelin peripheral protein . myelin protein zero (Charcot-Ma...

Myelin sheath

... varies with the interior diameter, ... Copepod myelin is compact in the outermost layers of a sheath , but often there ... In myelinated axons, schwann cells form the myelin sheath ... The main purpose of a myelin layer (or sheath ) is an increase in the speed at which impulses ... Shop th...

Myelin

...... Find Myelin and more Nutrition at Shopping.com. Shop 1000's of stores and compare prices. Free shipping on all items. In myelinated axons, schwann cells form the myelin sheath ... Myelin is considered a defining characteristic of the (gnathostome) vertebrates, ... ...
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