Schizophreni

Brain Scans Reveal How Gene May Boost Schizophrenia Risk

Clues about how a suspect version of a gene may slightly increase risk for schizophrenia* are emerging from a brain imaging study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH). The gene variant produced a telltale pattern of activity linked to production of a key brain messenger chemical. The study found that increased activity in the front of the...

Scientists move forward understanding of schizophrenia

A Scots-led medical research team has identified a new gene linked to major mental illness that links back to a previously discovered gene known to increase the risk of schizophrenia and depression. Scientists from the Universities of Edinburgh and Glasgow, together with scientists from the pharmaceutical company Merck, Sharp & Dohme Limited, report the discovery of the second gene, phosphod...

Prenatal exposure to famine increases risk of schizophrenia

People born during a famine in China have an increased risk of schizophrenia, consistent with previous research suggesting a link between fetal nutritional deficiency and schizophrenia, according to a study in the August 3 issue of JAMA, a theme issue on violence and human rights. Schizophrenia is a common form of severe mental illness characterized by thought disorder, hallucinations, and...

Engineered mouse mimics cognitive aspects of schizophrenia

Researchers have developed a mouse strain in which the abnormal activity of the dopamine machinery in a specific part of the brain causes cognitive and behavioral impairments mimicking those in human schizophrenics. The achievement is important, because creating an animal model of any schizophrenic characteristics has not been done before. And schizophrenia's genetic and physiological comp...

Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety

A small protein in the brain that has only recently been discovered and, paradoxically, induces both profound wakefulness and a less anxious state, may represent a novel target for the treatment of psychotic behavior and schizophrenia, according to new research presented at the 6th International Congress of Neuroendocrinology (ICN 2006). ICN 2006 is being held at the David L. Lawrence Convention...

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Quantitation of GAD67 Gene Expression in Prefrontal Cortex of Schizophrenia Patients Using the iCycler iQ Detection System and Molecular Beacons, Rev A

130 West Kingsbridge Road, Bronx, NY 10468 USA Schizophrenia is a severe mental illness that afflicts about 1% of the population (Strange 1992). Patients experience a variety of symptoms that have been divided into subgroups...

Schizophreni at Medicine News

Older men 'father' schizophrenics

Older fathers are more likely to have children with schizophrenia, research suggests. Men aged 50 or over are three times more likely to father a child with the illness compared to men of 27 or under. And men aged between 45 and 49 are twice as likely to have a child with schizophrenia. The scientists behind the research estimate that as many as one in four cases of schizophrenia cou...

Sex exploitation connected to Schizophrenia

According to researchers linking childhood sexual abuse and schizophrenia will further confuse patients of the mental illness. According to a research in the American Journal, half of the women admitted for psychiatric care in the study// were victims of sexual abuse. The principal researcher, John Fred from Arizona University, says the figures do not prove that abuse causes schizophrenia...

Schizophrenia detected early

Scientists have developed a computer test which they say has proved 100% precise in early tests. The computer programme is modelled on the human brain,// and has been devised to learn from experience like humans. The system, was developed at the University of British Columbia, by Peter Liddle, a psychiatrist specialising in brain imaging. The artificial brain reviews the brain scan...

No explanation on schizophrenia gene

Many scientists have drawn another blank in their search for a universally applicable genetic explanation for schizophrenia, binding the case for new approaches to researching the illness. A paper by Douglas F. Levison and colleagues report that despite earlier findings to the contrary, there is no close link between schizophrenia and genes on the long arm of chromosome 1.// The resear...

Gene glitches connecting pot with Schizophrenia

According to Japanese researchers, genetic abnormalities bound with marijuana-activated brain chemicals appear connected to schizophrenia. Hiroshi Ujike, a lead researcher, of the Okayama University, observed that this result supplies genetic evidence that marijuana// use can result in schizophrenia or a considerablelly increased risk of schizophrenia. Schizophrenia is one of the great...

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Investigational Study Evaluates the Effectiveness of Aripiprazole in Adolescents With Schizophrenia

- Findings from an Otsuka Pharmaceutical Co, Ltd. Sponsored StudyPresented at the American Psychiatric Association Annual Meeting - SAN DIEGO, May 23, 2007 /PRNewswire/ -- In a six-week study inadolescents (13- 17 years old) with schizophrenia, the OtsukaPharmaceutical Co., Ltd. and Bristol-Myers Squibb Company atypicalantipsychotic aripiprazole demonstrated significant improvementcompare...

New Study Analyses Confirm Once-Daily Seroquel XR Extended-Release Tablets as Effective Treatment for Schizophrenia

--Study Used To Support FDA Approval of SEROQUEL XR-- WILMINGTON, Del., May 22, 2007 /PRNewswire-FirstCall/ --AstraZeneca today announced that two analyses from a large-scalestudy that investigated the efficacy of SEROQUEL XR(TM) (quetiapinefumarate) Extended-Release Tablets, a once-daily medicine for thetreatment of schizophrenia in adult patients, were presented todayat the annual meeti...

New Long-Term Data Analyses for Bifeprunox Show Favorable Effects Versus Placebo in Stabilized Patients with Schizophrenia

Six-Month Data Show Bifeprunox Maintained StabilitySignificantly Longer than Placebo and had a Favorable Weight andLipid Profile Comparable with Placebo MARIETTA, Ga. and COLLEGEVILLE, Pa., May 22, 2007 - SolvayPharmaceuticals, Inc., Wyeth Pharmaceuticals, a division of Wyeth(NYSE:WYE), and Lundbeck A/S presented clinical study results onbifeprunox, an investigational treatment for...

BioLineRx Presents Data From Successful Phase I Trial for BL-1020 in Schizophrenia at American Psychiatric Association Conference

SAN DIEGO--(BUSINESS WIRE)--May 22, 2007 - BioLineRx Ltd.(TASE:BLRX), Israel's leading drug development company, reportedtoday data from its Phase I trial of BL-1020, the first GABAenhanced antipsychotic clinical candidate for the treatment ofschizophrenia. The trial demonstrated that the compound was welltolerated and demonstrated biochemical evidence of dopamineblockade which is indicativ...

New Data Show Early Non-Response to Antipsychotic Treatment May Be Strong Predictor of Subsequent Non-Response for People with Schizophrenia

Findings indicate early non-responders unlikely to subsequentlyrespond, have substantially more treatment costs, and may benefitfrom earlier change in treatment strategy COLORADO SPRINGS, Colo., April 03, 2007 /PRNewswire-FirstCall/-- New data presented at the 2007 International Congress onSchizophrenia Research (ICOSR) suggest that antipsychotic drugresponse be assessed earlier than is p...

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Schizophrenia

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