Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma
A novel delivery system that transports gene silencing nanoparticles into tumor cells has been shown to inhibit Ewing's sarcoma in an animal model of the disease. In this classic "Trojan horse" approach, a protein called transferrin that normally delivers iron into cells is modified to also smuggle into tumor cells siRNA (short interfering RNA) encased in nano-sized sugar polymers. The si...Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor
Researchers at the National Institute of Allergy and Infectious Disease (NIAID), a component of the National Institutes of Health (NIH), have identified a critical human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and certain forms of lymphoma. Kaposi's sarcoma is a major cancer associated with HIV/AIDS, and it typical...Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors
A study in the January 3 issue of the quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds that this risk persists for decades after the original retinoblastoma diagnosis. The findings emphasize the importance of regular medical surveillance for these patients, the authors say. </p...A - 20 cell line slides ( mouse: B lymphocyte; reticulum cell sarcoma ) from GeneTex
Description:Mouse A-20 cells were cultured in RPMI 1640 with 2 mM L-glutamine and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background staining. Each well is loaded...Kissing can cause Kaposi’s Sarcoma in AID
Kisssing may be responsible for a form of the herpes virus that causes an AIDS-related skin cancer called Kaposi’s sarcoma. Kaposi’s sarcoma causes purple skin blotches and can also attack the internal organs. The virus rarely causes sickness among people with normal disease defenses but attacks those with weakened immune system as in AIDS. The virus known as herpes virus 8...Effect of Osteosarcoma predicted by scans
Researchers have been studying about the outcome of the hitech scanning technologies recently. A scan that looks at glucose uptake in a tumour shows who has a poor prognosis. Osteosarcoma is a bone tumour which affects mainly younger people. //It's an unusual cancer and one where the outcome tends to be rather unpredictable. Researchers at the University of Germany have used a technique called...Virus Causing Kaposi's Sarcoma Discovered
Virus causing Kaposi's sarcoma herpesvirus (KSHV) and certain forms of lymphoma has been discovered, according to a recent report from NIAID.// Researchers at the National Institute of Allergy and Infectious Disease (NIAID) have identified a critical human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and cert...Risk Of Soft Tissue Sarcomas In Hereditary Retinoblastoma Survivors
A study by Ruth A. Kleinerman and his colleagues quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds that// this risk persists for decades after the original retinoblastoma diagnosis. The findings published in the January 3 issue of the Journal of the National Cancer Institute emphasizes the importance of regular med...Insights into Osteosarcoma in Cats and Dogs may Improve Palliative Care
Researchers at the University of Illinois have found that a molecular pathway known to have a role in the progression of bone cancer in humans is also critical to the pathology// of skeletal tumors in dogs and cats. Their work could lead to advances in the palliative care of companion animals afflicted with osteosarcoma. The research team, which included U. of I. pathobiology professo...Kaposi Sarcoma-Associated Herpesvirus/Human Herpesvirus 8
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
LUGANO, Switzerland--(BUSINESS WIRE)--Jul 9, 2007 - ZIOPHARMOncology, Inc. (NASDAQ: ZIOP) announces that positive interim datafrom an ongoing phase II trial of ZIO-201 (isophosphoramide mustard- IPM) to treat advanced sarcoma patients was presented at theEuropean Society of Medical Oncology (ESMO) meeting held July 5-8,2007 in Lugano, Switzerland. The abstract entitled, "Phase-I/IIStudy of...