Salmeterol

Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients

A recent three-way crossover study over six weeks by clinicians at the National Heart and Lung Institute, Royal Brompton Hospital, London has shown that Salmeterol produced a novel anti-neutrophilic effect among patients with mild asthma. The study was prompted by the long standing argument about t...

Perforomist(R) Inhalation Solution Data in Patients With Moderate to Severe COPD to Be Presented at the International Conference of the American Thoracic Society

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a LABA), the active ingredient in Perforomist Inhalation Solution. Perforomist Inhalation Solution should not be initia...

Dey, L.P. Highlights Perforomist(R) Inhalation Solution Data to Be Presented at the International Conference of the American Thoracic Society

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a LABA), the active ingredient in Perforomist Inhalation Solution. Perforomist Inhalation Solution should not be initiat...

St. Louis Named Top Asthma Capital for 2009

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta(2)-adrenergic agonist), one of the active ingredients in SYMBICORT. (7) SYMBICORT is not indicated f...

Next Safety Develops an Air-Based Asthma Medication Inhaler That Does Not Use a Refrigerant Propellant

...e platform offers the ability to deliver not only albuterol in air, but also other medications for treating asthma, such as fluticasone propionate and salmeterol xinofoate, the components of Advair." Certain chemical patents for Advair expired in August 2008. The device also provides an electronic outpu...

GlaxoSmithKline Statement on FDA Advisory Committee Vote on Use of Asthma Medicines Containing Long-Acting Beta-Agonists

...creased risk of serious asthma-related events when salmeterol is used appropriately with an ICS. In fact, the combination of salmeterol with an ICS (either as Advair or as Serevent plus ...-related outcomes, including hospitalization, when salmeterol was used without an inhaled corticosteroid or when...

Two Asthma Meds May Be Too Risky, FDA Panel Says

... only formoterol. Advair is a combination of both salmeterol and fluticasone (an inhaled cortocosteroid), while... has been irresponsible marketing of the products, salmeterol and formoterol, and irresponsible prescribing by m...thKline said in its statement: "The combination of salmeterol with an inhaled corticosteroid provides unsurpasse...

FDA Panel Mulls Safety of Asthma Meds

... of Iowa. "However, there has been irresponsible marketing of the products, salmeterol and formoterol, and irresponsible prescribing by many physicians." "Sinc...ith the FDA. GlaxoSmithKline said in its statement: "The combination of salmeterol with an inhaled corticosteroid provides unsurpassed asthma control to patie...

Hope for patients with COPD

...cine, published by the American Thoracic Society. "Pharmacotherapy with salmeterol plus fluticasone propionate, or the components, reduces the rate of decline...0 patients with moderate to severe COPD from 42 countries to receive either salmeterol (SAL; 50 g), fluticasone propionate (FP; 500 g), the two in...

Three-Year COPD Study Found No Increase in Cardiac Events With Advair(R) 500/50

...t of patients treated with Advair reported a cardiac adverse event, compared with 21 percent of those in the placebo group, 19 percent of those in the salmeterol group and 20 percent of those in the fluticasone propionate group. The rate of cardiac death was also lower in the Advair arm as compared with the pla...

Salmeterol in Medical Technology

AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R)

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta2-adrenergic agonist), one of the active ingredients in SYMBICORT. SYMBICORT is not indicated for...

Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta2-adrenergic agonist), one of the active ingredients in SYMBICORT. SYMBICORT is not indicated for the rel...

Nebulized Perforomist(TM) Inhalation Solution Provided Prolonged Bronchodilation and Increased Patient Satisfaction Compared to Albuterol/Ipratropium MDI

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a LABA), the active ingredient in Perforomist(TM) Inhalation Solution. Perforomist(TM) Inhalation Solution should not be in...

Study Found That Long Term Use of Advair Diskus(R) 250/50 Did Not Adversely Affect Bone Loss in Patients with COPD

...n Advair Diskus 250/50 (fluticasone propionate and salmeterol inhalation powder) and salmeterol - Study provid...ured at the lumbar spine and total hip compared to salmeterol alone. In this study, designed to show equivalent ... Effects of treatment with Advair Diskus 250/50 or salmeterol 50 mcg on BMD were evaluated in 186 patients (fema...

Newly Released Data on Onset of Effect and Patient Perception With SYMBICORT in Adults With Asthma

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta2-adrenergic agonist), one of the active ingredients in SYMBICORT. SYMBICORT is not indicated for the rel...

Results From One-Year Study Suggest Advair(R) Provides Important Benefits for African American Patients With Asthma

...combination of the long-acting beta-agonist (LABA) salmeterol and the inhaled corticosteroid (ICS) fluticasone p...ibute to the body of evidence which has found that salmeterol (a LABA) is not associated with an increase in ser...almeterol. In patients with asthma, medicines like salmeterol may increase the chance of asthma-related death. S...

AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta2-adrenergic agonist), one of the active ingredients in SYMBICORT. SYMBICORT is not indicated for the rel...

Study Analyzed SYMBICORT(R) in Children with Persistent Asthma

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta2-adrenergic agonist), one of the active ingredients in SYMBICORT. SYMBICORT is not indicated for the rel...

Concomitant Use of Nebulized Formoterol Fumarate and Tiotropium Provides Significant Improvement in Dyspnea, COPD Symptoms and Rescue Medication Use over Tiotropium Alone

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a LABA), the active ingredient in Perforomist(TM) Inhalation Solution. Perforomist(TM) Inhalation Solution should not be us...

Patients With Asthma and Seasonal Allergies Respond Better to Advair(R) for Their Asthma Than Singulair(TM)

...ung function when treated with Advair Diskus(R) (fluticasone propionate and salmeterol inhalation powder) as compared with Singulair (montelukast sodium). The res... a day. Advair contains salmeterol. In patients with asthma, medicines like salmeterol may increase the chance of asthma- related death. So Advair is not for peop...

Salmeterol in Biological Technology

FDA Approves SYMBICORT(R) for Chronic Obstructive Pulmonary Disease (COPD)

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta 2 -adrenergic agonist), one of the active ingredients in SYMBICORT (see WARNINGS in full Prescribing Inf...

New Patient Satisfaction Study With budesonide/formoterol Combination Therapy and fluticasone/salmeterol Combination Therapy in Adults With Asthma

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a long-acting beta2-adrenergic agonist), one of the active ingredients in SYMBICORT. SYMBICORT is not indicated for the rel...

Asthma Patients Not Adequately Controlled on ICS Alone More Likely to Benefit From Advair(R) Than Doubling the Dose of ICS

...witched to the equivalent dose of FP combined with salmeterol administered as Advair Diskus(R) (fluticasone propionate and salmeterol inhalation powder) compared with patients who rece...almeterol. In patients with asthma, medicines like salmeterol may increase the chance of asthma-related death. S...

PARI Respiratory's LC PLUS & PRONEB Ultra Deliver Dey, L.P.'s New COPD Therapy; Perforomist Launched Yesterday

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a LABA), the active ingredient in Perforomist Inhalation Solution. Perforomist Inhalation Solution should not be used in pat...

Mylan Inc. Subsidiary, Dey, L.P., Announces that Perforomist(TM) (Formoterol Fumarate) Inhalation Solution is Now Available for Maintenance Treatment of COPD

... (salmeterol) or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol. This finding with salmeterol may apply to formoterol (a LABA), the active ingredient in Perforomist(TM) Inhalation Solution. Perforomist(TM) Inhalation Solution should not be use...