SPARC

GPC Biotech Today Announced Results of Survival Analysis from the SPARC Trial

Overall Survival Results Do Not Achieve Statistical Significance IRVINE, Calif., Oct. 30 /PRNewswire-FirstCall/ -- Spectrum Pharmaceuticals, Inc.'s (Nasdaq: SPPI ) licensee, GPC Biotech, today announced that the Phase 3 SPARC trial evaluating satraplatin for the treatment of hormone-refra...

Four Pakistan Children Abused Daily: SPARC Report

The Society for the Protection of the Rights of the Child (SPARC), in its annual report has stated that cases of child abuse are on the rise in Pakistan , and states that around four children are sexually abused in the country everyday. Jahanzeb Khan, regional manager of SPARC speaking at t...

Tips from the American Journal of Pathology

...cancer. Am J Pathol 2009, 174: 1931-1939 sparc (Secreted Protein Acidic and Rich in Cysteine) in ...t the University of Washington, Seattle found that sparc may contribute to kidney disease. These findings ... podocytes upon injury. To define the role of sparc in kidney disease, Sussman et al examined immune-m...

Care Improvement Plus Recognized with Metropolitan Partnership in Aging Award

...ng stages. Recently, Care Improvement Plus announced that it has partnered with the Area Agency on Aging (ARC) to sponsor the DeKalb and Fulton County sparc coalition events, which provide immunizations and other valuable health services to area seniors. Those interested in learning more about future event...

Convenience is Key to Adult Flu Vaccinations

... (SPARC). A 2008 national survey commissioned by sparc reveals that nearly half (46%) of adults age 50 an...icans. In 2006, with additional support from RWJF, sparc directed a multi-state effort to assess the useful...nformation, visit http://www.rwjf.org . SPARC sparc (Sickness Prevention Achieved through Regional Col...

Creator of PubMed Central biomedical research database recognized for outstanding citizen service

...ican public places in being able to access and use the product of their collective investment in research," said Heather Joseph, Executive Director of sparc (the Scholarly Publishing and Academic Resources Coalition) and administrator of the Alliance for Taxpayer Access. "Dr. Lipman, the PubMed Central tea...

NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents

...n human lung cancer cells. Our functional assay suggested that increases of sparc and other anti-metastatic genes were important for NSAIDs to inhibit tumor ... elucidated the underlying mechanism and demonstrated that up-regulation of sparc in human lung cancer cells was mediated via inhibition of DNA methyltransfe...

Public access mandate made law

... access to the research we need. Congress has just unlocked the taxpayers $29 billion investment in NIH, said Heather Joseph, Executive Director of sparc (the Scholarly Publishing and Academic Resources Coalition, a founding member of the ATA). This policy will directly improve the sharing of scientific...

Pharmion and GPC Biotech Announce Results of Overall Survival Analysis From the Satraplatin Pivotal Phase 3 Trial

...estigators and patients, as well as their families, who participated in the sparc trial." "These results are clearly disappointing and will impact the EMEA ...rporation, including summary statements relating to top line results of the sparc trial and summary statements relating to the potential efficacy and safety ...

Pak Has South Asias Highest Infant Mortality Rate: Report

...nd infant mortality rate in South Asia. In a report prepared by it, sparc further said that around 10 million children work to assist their families....he conditions and environment in which the children are living in Pakistan, sparc official Irfan Raza said. Commenting on education, the report said ...

SPARC in Medical Technology

Additional Data From Satraplatin SPARC Phase 3 Trial Presented at European Association of Urology Congress

Patients treated with Satraplatin Demonstrated Statistically Significant Improvement in Pain Response and PSA Response Rates BERLIN, March 22, 2007 /PRNewswire-FirstCall/ -- Pharmion Corporation and GPC Biotech AG today announced additional data from the double-blind, randomized satraplatin Phase ...

Abraxis BioScience Presents Pre-Clinical Findings That Support Role of SPARC Expression in Cancer and the Role of the Nanoparticle Albumin Bound (nab) Technology Platform in Targeting the Pathway

LOS ANGELES--(BUSINESS WIRE)--Apr 19, 2007 - Abraxis BioScience, Inc. (NASDAQ:ABBI), an integrated, global biopharmaceutical company, announced results from two pre-clinical studies that support the role of SPARC (secreted protein acidic and rich in cysteine) expression in cancer and Abraxis' nanop...

Additional Efficacy Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at Annual Meeting of American Urological Association

-- Median time to pain progression is 66.1 weeks for the satraplatin arm compared with 22.3 weeks for the placebo arm -- Hazard ratio of 0.64 (95% CI: 0.51-0.79, p<0.001), representing a 36% reduction in the relative risk of pain progression MARTINSRIED/MUNICH, Germany, May 21, 2007 /PRNewswire-Fi...

Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting

- All pre-specified subset analyses of progression-free survival in the SPARC Phase 3 trial consistently demonstrate a reduction in relative risk of disease progression for patients receiving satraplatin. These analyses included prior Taxotere use, geographies, as well as presence or absence of pai...

Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting

-- All pre-specified subset analyses of progression-free survival in the SPARC Phase 3 trial consistently demonstrate a reduction in relative risk of disease progression for patients receiving satraplatin. These analyses included prior Taxotere use, geographies, as well as presence or absence of pa...

Abraxis BioScience Presents Data from Pre-Clinical Study That Provide Evidence for Chemotherapy-Induced Angiogenesis and Rationale for Combining nab-Paclitaxel (Abraxane) with Anti-Angiogenic Agents to Increase Tumor Response

...ab-paclitaxel in combination with bevacizumab as an effective antitumor agent. Abraxis continues to explore the role of nab-technology for targeting sparc and other biological pathways, as well as for the development of new therapeutic candidates such as nab-docetaxel (ABI-008), the mTOR inhibitor nab-ra...

Abraxis BioScience Presents Results from Pre-Clinical Study That Demonstrates nab-Rapamycin's Robust Antitumor Properties and Ability to Target Intracellular Sites Such as the mTOR Pathway

... Abraxis plans to commence Phase I clinical trials with nab-rapamycin in 2007. Abraxis continues to explore the role of nab technology for targeting sparc and other biological pathways, as well as for the development of new therapeutic candidates such as nab-docetaxel (ABI-008) and the HSP90 inhibitor na...

Pharmion to Present Clinical Data on Commercial and Pipeline Products at 2007 American Society of Clinical Oncology (ASCO) Meeting

...ubject of an oral presentation at the Conference. The oral presentation will discuss the progression-free survival results of the randomized Phase III sparc study (Satraplatin and Prednisone Against Refractory Cancer) in hormone-refractory prostate cancer patients. In addition, Pharmion and GPC Biotech wil...

SPARC in Biological News

Taxpayer Alliance applauds bill to broaden access to federal research results

...d graduate students alike," noted Nick Shockey, Student Outreach Fellow for sparc and recent graduate of Trinity University, San Antonio. "This legislation w...ded Heather Joseph, spokesperson for the Alliance and Executive Director of sparc (the Scholarly Publishing and Academic Resources Coalition). This bill refl...

Sun Microsystems and Aware, Inc. Announce Integration of Aware's BioSP with Sun Identity Management Solutions

...oSP also delivers wire-speed performance on transport/message-level security by taking advantage of on-chip cryptographic acceleration provided by Sun sparc Enterprise T5120 and T5220 systems. About BioSP BioSP is a modular, flexible, server-based software platform that enables developers and integrato...

2 new therapies show promise for cancer patients

...esearch program, Von Hoff and colleagues found the sparc (Secreted Protein Acidic and Rich in Cysteine) pro...commonly found in pancreatic cancer specimens. The sparc protein is being investigated by Abraxis BioScienc...der contract with Abraxis, was utilized to analyze sparc in the pancreatic cancer patients in the trial. ...

New whitepaper offers options for university implementation of NIH policy

...shington, DC and Cambridge, MA February 29, 2008 sparc (the Scholarly Publishing and Academic Resources C...advisor to Science Commons. In 2004 he worked with sparc to develop the popular sparc Author Addendum ( http://www.arl.org/sparc/author/...

Mandate for public access to NIH-funded research poised to become law

...es law. Last nights Senate action is a milestone victory for public access to taxpayer-funded research, said Heather Joseph, Executive Director of sparc (the Scholarly Publishing and Academic Resources Coalition, a founding member of the ATA). This policy sets the stage for researchers, patients, and t...

Americans support free access to research

...t from the American public demonstrates that the demand for public access has reached a critical juncture," said Heather Joseph, Executive Director of sparc (Scholarly Publishing and Academic Resources Coalition, an ATA founding member). "As scientists work to counter the Avian flu, develop energy alternat...

SPARC in Biological Technology

Frying spam for the masses

...ption fees from a three-tiered system to a one-size-fits-all $999 per year. The other big change is the move from a product based on Sun Solaris on sparc to Linux. While Solinus viewed the move to Linux rather than Sun's Opteron platform as a favorable business proposition, the move also injected the 41...