Arthritis Drug – Rofecoxib , Found To Increase Heart Attack Ris

Based on findings of a recent study researchers say the arthritis drug rofecoxib (Vioxx) is found to increase the risk of heart attack. For the study researchers looked at health records of about 114,000 elderly people // who had never had a heart attack when the research started. About 70 percent ...

Risk Of Colorectal Polyps Recurrence Can Be Controlled By Rofecoxib

A new study shows that COX-2 inhibitor 'Rofecoxib' might be effective in controlling the recurrence of colorectal cancer. // According to a new, 'A Randomized Trial of Rofecoxib for the Chemoprevention of Colorectal Adenomas,' being published in Gastroenterology, the journal for the members of...

COX-2 expression is marker for cancer development in some benign breast biopsies

...notes that one strategy to help manage patients may be to use a COX-2 inhibiting agent, such as celecoxib ( http://en.wikipedia.org/wiki/Celecoxib )or rofecoxib ( http://en.wikipedia.org/wiki/Rofecoxib ), to prevent breast cancer from developing. This study raises the possibility of targeting COX-2 in selected...

Avandia Improves Quality of Life in Diabetes Patients

...of the drug-use and drug-approval processes in the United States, Psaty and Furberg write, comparing the situation to the withdrawal of the painkiller rofecoxib (Vioxx) from worldwide markets in 2004. The Cochrane reviewers concur, saying, Current drug approval for antidiabetic medications and possi...

Combining NSAIDs With Chemotherapy May Improve Cancer Therapy

... 60 percent of head and neck cancer cells under the study conditions. None of the other 10 NSAIDs in the study, including aspirin, naproxen (Aleve) or rofecoxib (Vioxx), showed effective anticancer activity. The experiments also indicated that celecoxib and sulindac sulfide's anticancer activity was me...

Ibuprofen Risky for Heart Patients?

... Worldwide, over 80 million people were prescribed rofecoxib at some time. On September 30, 2004, Merck voluntarily withdrew rofecoxib from the market because of concerns about increase...stroke associated with long-term, high-dosage use. rofecoxib was one of the most widely used drugs ever to be w...

Painkillers Linked to Still More Problems

...at an analysis of 114 studies that involved over 116,000 people showed that rofecoxib commonly known as Vioxx "was associated with increased renal and (heart) ar...he U.S. Food and Drug Administration said, "What does this all mean? First, rofecoxib (Vioxx) increases the risk of acute myocardial infarction at low and high d...

COX-2 inhibitors Lessen Breast Cancer Risk

... Selective usage of COX-2 inhibitors like rofecoxib (Vioxx) and celecoxib (Celebrex) reduces breast cancer risk by 71%, accordi...g celecoxib reduced the risk of breast cancer by 83%, a daily dose of 25 mg rofecoxib reduced the risk of breast cancer by 64%. Regular use of non-selective COX-...

An effective pain killer

...lways present in the body, and COX-2, which is produced during inflammation.Newer anti-inflammatory drugs, such as celecoxib (trade name Celebrex) and rofecoxib (Vioxx), work selectively against COX-2. "But they are very expensive, and currently a very significant contributor to the PBS," explained Professor R...

Aspirin may reduce he risk of colon cancer

...OX-2) inhibitors like celecoxib or rofecoxib. Other than aspirin, some beneficial effects were also noted for the drugs celecoxib (Celebrex) and rofecoxib (Vioxx). The results showed apart from reduction in the risk of cancer recurrence, the risk of death from cancer also reduced by 48%. Referen...

Rofecoxib in Biological News

COX-2 inhibitors significantly reduce risk of cancer

...ers. Harris and his colleagues studied the use of celecoxib (Celebrex), rofecoxib (Vioxx), regular aspirin, low-dose aspirin, ibuprofen and acetaminophen amo...ss breast cancer. Specifically, they found that those who used celecoxib or rofecoxib for at least two years appeared to benefit the most, experiencing a 71 perc...