Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...It's not all genetic: Common epigenetic problem doubles cancer risk in mice
In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people have this double protein dose as well. In...Male circumcision reduces risk of HIV transmission from women to men
The first study to examine the probability ofHIV infection per act of heterosexual sex among a population withmultiple sexual partners has found that uncircumcised men have morethan twice the risk of acquiring HIV than do circumcised men.In the study, published in the Feb. 15 issue of The Journal ofInfectious Diseases, now available online, Jared Baeten and colleaguesfrom the United States...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
A widely-used class of drugs that keep the HIV-virus infection from progressing to AIDS may cause serious and potentially lethal heart rhythm disturbances in some patients. The finding of a Mayo Clinic-led investigation appears in the current edition of The Lancet. In collaboration with colleagues from the HIV Program of Hennepin County Medical Center, Minneapolis; the University of Minn...CEOs Gone Wild? Risks and rewards in the executive suite
It happened again. Ano...Wireless Are you at Risk and Liable?
Recently, I was at a security conference and stayed at a hotel, which promoted wireless Internet service for $9.95 per day. They claimed that they had implemented it so only those on the first floor could get wireless Internet access. I do not purchase wireless Internet service when Im at seminars because I usually get access to my network at the seminar hosts office. Out of curiosity,...Fusion 2007: IT threats make risk management paramount
The CEO's head, too. If there was a consistent theme during the , it was that threats are bombarding business organizations from many directions, and risk management has surpassed security as the paramo...Early Stage, Step 8: Misclassifying workers brings risk
- Wisconsin's unemployment insura...Fusion 2007: CA chief says IT complexity raises risk
That according to John Swainson, president and CEO of 2007 Fusion CEO-CIO...Use of Cellular Phones associated with Increased risk of Brain Tumors
A recent article published by a team in Sweden suggests that there is an increased risk of brain cancer in the areas of highest exposure in patients using digital telephones (Case Control Study on Radiology work, Medical X-Ray Investigations, and Cellular Telephones as Risk Factors for Brain Tumors, Hardell, et al, May 4, 2000, www.medscape.com). Their analysis focused on the effect of d...Virus Level could Predict Cervical Cancer Risk
Cervical cancer is one of the most common cancers in women. If it is caught and treated early, it is curable in most cases.// The Pap smear is the standard screening method for the disease. It is used to detect unusual, precancerous changes in cervical cells. Two strains of the human papilloma virus (HPV) are associated with an increased chance of getting the cancer, but not all women who...Feeling depressed? You may be at higher risk of STROKE
Those who suffer symptoms of depression are at an increased risk of stroke, according to researchers from the Centers for Disease Control and Prevention. In particular, depressed African Americans showed the largest increase in stroke risk. Those people with the highest levels of depression had a 73% increase in their risk of stroke. However, it is not clear if the depression actually c...Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
Measurement of serum progesterone levels may be helpful in deciding which emergency department patients with no strong clinical signs are at low risk of ectopic pregnancy, according to a report in the August issue of the Annals of Emergency Medicine. They measured progesterone levels in 716 first-trimester patients who presented to an emergency department with abdominal pain or...Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical...Hybrid Capture® 2 High-Risk HPV DNA Test®
Description:An In Vitro Nucleic Acid Hybridization Assay with Signal Amplification using Microplate Chemiluminescence for the Qualitative Detection of Human Papillomavirus (HPV) Types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 in Cervical Specimens....Apolipoprotein EMutation Detectionfor Cardiovascular Risk
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk
Harvard Medical School Contributing Editor Atherosclerosis is the fundamental process in coronary artery disease, stroke, and many other vascular diseases. It is responsible for more than half of the disease burden of the United States, with an annual cost of over $100 billion. This includes over 1.5 million my...