Priming embryonic stem cells to fulfill their promise
Bioengineering researchers at the Universityof California, San Diego have invented a process to help turn embryonicstem cells into the types of specialized cells being sought as possibletreatments for dozens of human diseases and health conditions. SangeetaBhatia and Shu Chien, UCSD bioengineering professors, and ChristopherJ. Flaim, a bioengineering graduate student, described the cell-cult...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
The replenishment of missing neurons in thebrain as a treatment for Parkinson disease reached the stage of humantrials over 15 years ago, however the field is still in its infancy.Researchers from Kyoto University have now shown thatdopamine-producing neurons (DA neurons) generated from monkey embryonicstem cells and transplanted into areas of the brain where these neuronshave degenerated i...Sea skate experiment sheds light on human cell transport
Along with Mark Musch, a longtime University of Chicago collaborator, Goldstein conducted an experiment with the red blood cells of skates to understand how these skinny, graceful fish can swim from salt water to fresh water. For humans, such a drastic environmental change would prompt an equally drastic physiological change: Our cells would take in too much water, diluting blood and other body f...Experiments provide proof of how traveling in groups protects insects
Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the African plains. and young locusts also sometimes unite with their...Experiments provide proof of how traveling in groups protects insects
Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the African plains. and young locusts also sometimes unite with their...Glutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich
Description:Biochem/physiol Actions: Glutathione-S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is presen...Thermo Sequenase Dye Primer Manual Cycle Sequencing Kit from USB Corp.
Description:The Thermo Sequenase Dye Primer Manual Cycle Sequencing Kit is designed to be used with fluorescent dye-labeled primers and high-resolution fluorescence scanners. Sequencing reactions involve a termination step followed by standard slab gel electrophoresis and scanning of the gel to detect fluorescently tagged sequencing products. The kit components have been optimized for sequencing direc...Breeding and Maintenance (Nonhuman Primates) from Alpha Genesis, Inc.
Description:AGI provides both long and short-term enriched housing for nonhuman primates and other laboratory animals in both quarantine and non-quarantine settings on a per diem basis. Breeding services are also available utilizing our state-of-the-art social housing and nursery facilities. In addition, AGI is equipped with on site CDC quarantine facilities. Primate housing and CDC quarantine systems...Mast Cell Degranulation colorimetric Assay Kit from CHEMICON
Description:Degranulation, the secretion of cytoplasmic granules, is a key step in the inflammatory response of leukocytes (e.g. basophils, neutrophils, eosinophils, and mast cells). In addition to histamine, these secretory granules contain many proinflammatory mediators including heparin, cytokines, chemokines, and many proteases (Hallgren, 2001). Tryptase, a tetrameric serine proteinase, has emerged as th...Bioactive Peptide synthesis from Primm Biotech, Inc.
Description:Custom design The Bioactive peptides are molecules of peptidic nature or origin which display a biological behaviour or activity which can be developed at the industrial level for pharmaceutical, diagnostic, chemical and agro-food applications. In this way it is possible to obtain modified peptides with superior properties for therapeutic applications. Primm offers a design strategy for devel...Human Primary Preadipocytes and Differentiated Adipocytes
Zen-Bio, Inc. Stratagene Michael R....Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits
Allelic discrimination kits with excellent specificity, sensitivity, andassay throughput Stratagene Because of their unique hairpin conformation, molecular beacon probes canrecognize single base differences, making them ideal for mutation detection andallelic discrimination. Base...Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance
Stratagene We introduce six pairs of control RT-PCR primers that are designed todetect specific human gene transcripts with various expression levels. Theseprimer sets provide insight into whether cDNA synthesis has been effective forall ab...RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes
Stratagene Cloning Systems from the cDNAsequences of mismatch repair genes. These genes code for specialized proteinsthat participate in correcting areas of base mispairing in DNA. We have...Gene-Specific Primers for NMDA Receptor Subunits
Robert Buchner Peter L. Pingerelli Michael D. Browning Mary Ellen Simcox Stratagene Cloning Systems, Inc. Stratagene is now offering gene-specific primer sets for the rat and humanNMDA receptor. In this article, we describe using these primers in reversetran...PRIMARY PULMONARY HYPERTENSION GENE DISCOVERED
The discovery of the gene associated with the inherited form of primary pulmonary hypertension (PPH) by Drs. Jane H. Morse of Columbia University and James A. Knowles of the Columbia Genome Center is indeed a major breakthrough. Their study, funded in part by the National Heart, Lung, and Blood Institute at the National Institutes of Health and published in the September issue of th...Indian Prime Minister has successful Knee Replacement Surgery
Mr. Atal Behari Vajpayee, the Prime Minister of India has successfully undergone left knee joint replacement by Dr. Chittaranjan Ranawat at the Breach Candy Hospital in Mumbai. "The operation, which started at around 10 a.m., was completed by 11.15 a.m. and went on very well, to my satisfaction," Dr. Ranawat said at a press briefing. ``He (Mr. Vajpayee) was awake and comfortable throughout the op...Experimental treatment for Ebola Virus Shows promising results in mice
Scientists at the Center for Disease Control and Prevention (CDC) in Atlanta, Georgia, have said that an experimental treatment for the deadly Ebola virus has shown promising results in mice. In the study, researchers led by Dr. Manish Gupta took antibodies from the immune systems of mice that had survived infection with the deadly Ebola virus and injected them into other Ebola-free mice...Experimental drug to fight flu
RECENT research has shown that new compounds developed for preventing and treating the flue have shown promise in animal studies, and may require only one dose to be effective.// The compounds, known collectively as multimeric zanamivir, are based on the existing flu drug relenza, or zanamivir, which the U.S. Food and Drug administration approved in 1999 for treating influenza A and B. R...Ziegler Double Ended Lacrimal Dilator
Description:Double ended dilator probes with gentle curve. Stainless steel. Round knurled handle with polished finish. Overall length: 5.3 inches....Castroviejo Double Ended Lacrimal Dilator
Description:One end with needle point and other end with medium taper. Stainless steel. Round knurled handle with polished finish. Overall length: 5.7 inches....Hasford Double Ended Lacrimal Dilator
Description:Abrupt taper 2 mm from the end, then more gradual taper so that quick dilation of the punctum is obtained. Stainless steel. Round knurled with polished finish. Overall length: 5.5 inches....Wilder Lacrimal Dilator - Short
Description:Taper with blunt tip. Stainless steel. Round knurled handle with polished finish. Taper : Short 19 mm. Overall length: 3.9 inches....Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
LUGANO, Switzerland--(BUSINESS WIRE)--Jul 9, 2007 - ZIOPHARMOncology, Inc. (NASDAQ: ZIOP) announces that positive interim datafrom an ongoing phase II trial of ZIO-201 (isophosphoramide mustard- IPM) to treat advanced sarcoma patients was presented at theEuropean Society of Medical Oncology (ESMO) meeting held July 5-8,2007 in Lugano, Switzerland. The abstract entitled, "Phase-I/IIStudy of...ENDEAVOR IV Clinical Trial Meets Primary Endpoint
MINNEAPOLIS--(BUSINESS WIRE)--Jul 2, 2007 - Medtronic, Inc.,(NYSE:MDT) today announced that a review of data from the ENDEAVORIV Clinical Trial indicates that the trial has met its primary,non-inferiority endpoint. The ENDEAVOR IV Clinical Trial is a randomized, single-blindtrial evaluating the safety and efficacy of the Endeavor(TM) DrugEluting Coronary Stent as compared to the TAXUS Pac...Ablynx Announces Interim Results of First Nanobody Phase I Study of ALX-0081 (ANTI-VWF)
GHENT, Belgium, 2 July, 2007 -- Ablynx today announced positiveinterim results from the ongoing Phase I study of its leaddevelopment programme, ALX-0081, an anti-thrombotic treatment.ALX-0081 is a novel ´first-in-class´ therapeuticNanobody® targeting von Willebrand Factor (vWF), which canreduce the risk of thrombosis in patients with acute coronarysyndrome. The Pha...