Navigation Links
Ribonuclease in Medical News

Enzyme with a sugar antenna

... Angewandte Chemie , scientists led by Carlo Unverzagt at the University of Bayreuth (Germany) have now successfully used a new strategy to synthesize ribonuclease C (RNase C), a glycosylated bovine pancreatic enzyme. Sugar components play an important role in the water solubility, stability, and folding of gly...

Alfacell Announces Management Update

...the end of January 2009. About ONCONASE (R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whi...

Alfacell Reports Financial Results for First Quarter of Fiscal 2009

...the planned NDA submission. About ONCONASE (R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whi...

Brain Tumor Drug in Frogs A New Report

...reatment of the future.Amphinase is a version of a ribonuclease enzyme that has been isolated from the oocytes (eg... in the future.Amphinase is the second anti-tumour ribonuclease to be isolated by Alfacell Corporation from Rana p...velopment and understanding of our family of novel ribonuclease based therapeutics with the potential to help pati...
Ribonuclease in Medical Technology

Alfacell Provides Shareholder Update

...dent, Chief Operating Officer About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Provides ONCONASE(R) NDA Submission Update

...e submission of its NDA. About ONCONASE (R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whi...

Paper in Molecular Cancer Therapeutics Reports that a Novel Combination of Alfacell's ONCONASE(R) and Rosiglitazone Induces a Synergistic Apoptotic Effect in Several Cancer Cell Lines

...ortant role in treating the disease." About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Announces ONCONASE(R) Distribution and Marketing Agreement with Megapharm for Israel

...essful collaboration with Megapharm." About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Corporation Announces Preliminary Results From ONCONASE(R) Phase IIIb Clinical Trial

...Alfacell's Web site at http://www.alfacell.com . About ONCONASE(R) ONCONASE is a first-in-class product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell's ONCONASE(R) Shows Potential as Radiation Sensitizer for Lung Cancer Treatment

...velops in, and confounds the treatment of NSCLC." About ONCONASE(R) ONCONASE is a first-in-class product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Pre-Clinical Data Show Intracellular Pathways Affected by ONCONASE(R)

...teins and to bring them forward into the clinic." About ONCONASE(R) ONCONASE is a first-in-class product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Updates Status of ONCONASE(R) Phase III Clinical Program

...tudy and receive at least one dose of study drug. About ONCONASE(R) ONCONASE is a first-in-class product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Reports Financial Results for First Quarter of Fiscal 2008

...eb site at http://www.alfacell.com . About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Updates Status of ONCONASE(R) Phase III Clinical Program

...r to discuss the company's fiscal 2007 performance. About ONCONASE(R) ONCONASE is a first-in-class product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...
Ribonuclease in Biological Technology

Alfacell Provides ONCONASE(R) NDA Submission Update

...fective as of January 1, 2009. About ONCONASE (R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whi...

Alfacell's ONCONASE(R) and R-Amphinase Show Anti-Tumor Activity in Chronic Lymphocytic Leukemia and Acute Myeloblastic Leukemia Cells

...therapy in this disease. About ONCONASE (R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whi...

Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results

...CONASE clinical development program." About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Paper in Cell Cycle Reports Alfacell's ONCONASE(R) Targets siRNA

...ioma that failed prior chemotherapy." About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Hires Advisors to Advance Strategic Alternatives

... has approved a specific transaction. About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Reports Financial Results for Third Quarter of Fiscal 2008

...eb site at http://www.alfacell.com . About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Announces Retirement of Chief Executive Officer

...fic foundation she has built for us." About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Reports Financial Results for Second Quarter of Fiscal 2008

...eb site at http://www.alfacell.com . About ONCONASE(R) ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell Announces ONCONASE(R) Purchase and Supply Agreement with Scientific Protein Laboratories

...evelopment and straight through to commercial launch. About ONCONASE(R) ONCONASE is a first-in-class product candidate from Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells whil...

Alfacell to Host Webinar on RNA Interference-Like Mechanics of RNase Therapeutics on Nov. 29

...ters will Include World-Renowned RNase and RNA Researchers SOMERSET, N.J., Oct. 25 /PRNewswire-FirstCall/ -- The RNA interference- like mechanics of ribonuclease (RNase) therapeutics will be the focus of scientific presentations in a Nov. 29 Webinar hosted by Alfacell Corporation (Nasdaq: ACEL ). Moderated by...
Ribonuclease in Biological Products

Rnase-free Ribonuclease Inhibitor from Chimerx

Description: A very potent Rnase free Ribonuclease Inhibitor that is effective over a broad range of temperatures and pH's. This protein does not inhibit SP6, T7, or T3 RNA polymerase, AMV and M-MLV reverse transcriptase or Taq DNA polymerase. For bulk purchases contact lloconne@molbiores.com....
Company:Chimerx

RNase ONE™ Ribonuclease from Promega

Description: RNase ONE Ribonuclease is a 27kDa periplasmic enzyme from E. coli that catalyzes the degradation of RNA to cyclic nucleotide monophosphate (NMP) intermediates. Slower hydrolysis further catalyzes the degradation of these intermediates to 3-NMPs (1). RNase ONE Ribonuclease is one of the few known RN...
Company:Promega

RNaseOUT Recombinant Ribonuclease Inhibitor from Invitrogen

Description: RNaseOUT Recombinant Ribonuclease Inhibitor is a potent noncompetitive inhibitor of pancreatic-type ribonucleases such as RNase A. Like other RNase inhibitors RNaseOUT Recombinant Ribonuclease Inhibitor is an acidic protein with a molecular weight ~52 kDa. RNaseOUT inhibits RNase A RNase B and RNas...
Company:Invitrogen

GeneChoice RNA Safe Recombinant Ribonuclease Inhibitor from GeneChoice, Inc.

Description: Ribonuclease Inhibitor is a recombinant protein that has been shown to help maintain the integrity of RNA in the preparation of cDNA by reverse transcription, in vitro RNA transcription, and in vitro protein synthesis. RNA Safe Inhibitor tightly binds RNases in a 1:1 ratio. It inhibits a broad ran...
Company:GeneChoice, Inc.

Recombinant RNasin® Ribonuclease Inhibitor from Promega

Description: Natural and Recombinant RNasin Ribonuclease Inhibitors have broad spectrum RNase inhibitory properties, including the inhibition of eukaryotic RNases of the neutral type (1). The 50kDa protein exerts its inhibitory effect by noncovalently binding to RNases in a 1:1 ratio. The Ki value for the bindi...
Company:Promega

MAXIscript SP6/T7 Kit from Ambion

Description:...scription Kits synthesize RNA probes with specific activities reaching 1 x 10 9 cpm/g. High specific activity, single-stranded RNA probes are used in ribonuclease protection assays, in situ hybridization, and blot hybridizations. MAXIscript Kits can also be used for the synthesis of modest amounts of unlabeled R...
Company:Ambion

5X MEGAscript® T7 Kit from Ambion

Description:...ly incorporates many modified nucleotides Kits specific for templates with T7, T3 and SP6 RNA polymerase promoters All kits contain SUPERaseIn ribonuclease Inhibitor ...
Company:Ambion

HIV Volume 2 (Biochemistry, Molecular Biology and Drug Discovery) from Promega

Description:...nd information, detailed practical information and methods for the study of major HIV proteins including: the HIV growth cycle; reverse transcriptase, ribonuclease H, integrase and protease. Expression of HIV proteins using baculoviruses; RNA binding assays; Tat and Rev assays; HIV/CD4 interactions; transient ass...
Company:Promega

StabMRT Maxi Kit from RNAworks

Description:...l molecular biology applications including storage, transport, handling, analysis by gel electrophoresis, Agilent Bioanalyser 2100, mass spectrometry, ribonuclease protection assays and Northern blotting. Protocols on line on RNAworks website A free MRT-RNA sample is available on request from RNAworks. ...
Company:RNAworks

StabMRT Plus Mini Kit from RNAworks

Description:...ications including RT-PCR and microarrays, storage, transport, handling, analysis by gel electrophoresis, Agilent Bioanalyser 2100, mass spectrometry, ribonuclease protection assays and Northern blotting. Protocols on line on RNAworks website A free MRT-RNA sample is available on request from RNAworks. ...
Company:RNAworks
Ribonuclease in Biological Dictionary

Ribonuclease

Ribonuclease is a type of nuclease that catalyzes the degradation of RNA into smaller components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7... Ribonuclease A (RNase A) is an endonuclease that cleaves singl...

Tertiary Structure

...on of protein tertiary structure (Ab Initio) ... The tertiary structure of proteins is maintained by a host of weak, non-covalent ... ribonuclease has several disulphide bonds stabilising its tertiary structure . ... Tertiary structure is stabilized by noncovalent interactions and, in s...

RNase

... ribonuclease (commonly abbreviated RNase ) is a type of nuc...e turnover ribozymes in nature (the other ... ribonuclease P ( RNase P) is a type of ribonuclease which cleaves RNA. RNase P is unique from other ...
Other Tags
(Date:8/22/2014)... 2014 Natural Clear Vision , a ... his own vision from legally blind to perfect 20/20 vision ... review. , “There is a huge portion of the ... function, and most people just think that’s the way it ... that can be pretty risky at times,” reports Michaels. “This ...
(Date:8/22/2014)... deletion in advanced non-small cell lung cancer (NSCLC) ... in epidermal growth factor receptor (EGFR) tyrosine kinase ... BIM deletion independently predicts overall survival (OS) of ... activate the programmed cell death also known as ... been detected in 12.8% of the Asian population ...
(Date:8/22/2014)... (RA), a complex autoimmune disease that affects 1 ... not only cope with pain, disability and joint ... work, family life and marital functioning. While many ... and disability is common. In addition, some patients ... or side effects. Because of this, there is ...
(Date:8/22/2014)... London, UK (PRWEB) August 22, 2014 ... more magnetic for some clinical applications due to ... of the emerging innovations in ultrasound, such as ... imaging, are expected to keep the market moving ... as increasing mobility can enhance not only the ...
(Date:8/22/2014)... Wisconsin (PRWEB) August 22, 2014 Mueller ... for Plantar Fasciitis, an exciting new product that provides ... you to stay active while you heal. The package ... is truly a new technology – it is not ... , FasciaDerm® PFTape™ System for Plantar Fasciitis ...
Breaking Medicine News(10 mins):Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2Health News:Deletion predicts survival in advanced non-small cell lung cancer 2Health News:Study shows cognitive-behavioral coping skills training has positive effects on rheumatoid arthritis 2Health News:Global Top Ultrasound Market Suppliers Assessed in New VPG Research Report Available at MarketPublishers.com 2Health News:Global Top Ultrasound Market Suppliers Assessed in New VPG Research Report Available at MarketPublishers.com 3Health News:Mueller Introduces FasciaDerm® PFTape™ System for Plantar Fasciitis 2
(Date:8/21/2014)... previously unknown process for harvesting energy and producing oxygen ... State University scientist has discovered. The discovery lays the ... harvesting energy from the Sun, and understanding dense blooms ... lakes worldwide. A paper describing the discovery will be ... the journal Science on 21 August 2014. ...
(Date:8/21/2014)... A ubiquitous skin fungus linked to dandruff, eczema and ... tracked to even further global reachesincluding Hawaiian coral reefs ... sea vents. , A review in the scientific journal ... distribution of the fungi of the genus Malassezia ... environmental sequencing datasets from around the world. , University ...
(Date:8/21/2014)... intake, health and quality of life of older adults ... the University of Waterloo receiving close to $1.5 million ... (CIHR). , Professor Heather Keller, of the Faculty ... research chair in nutrition and aging, will receive $979,000 ... in long-term care homes are poorly nourished. The project ...
Breaking Biology News(10 mins):Hot-spring bacteria reveal ability to use far-red light for photosynthesis 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 3From dandruff to deep sea vents, an ecologically hyper-diverse fungus 2Grants will fund landmark aging research at Waterloo 2
Other Contents