Rhesus

Cross-species transplant in rhesus macaques is step toward diabetes cure for humans

St. Louis, Oct. 18, 2007 With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys all without the need for risky immune suppression d...

Nepali Rhesus May be Used as an Alternate for HIV/AIDS Research

Scientists have found that Nepali rhesus is by all means a suitable alternate for the Indian-origin macaques, which is currently been used in biomedical research. // The Nepali species can be used in order to assuage the prevailing shortage of laboratory animals used for developing of vaccines for ...

Lighter Meals May Bring Longer Life

...f many diseases in yeast, worms, flies and, as Sierra pointed out, in some strains of mice. The new, two-decade-long study ultimately involved 76 rhesus monkeys, all of whom started the study as adults (aged 7 to 14 years). Thirty-three monkeys are still alive, 13 of whom are allowed to eat as they lik...

Reduced diet thwarts aging, disease in monkeys

...tudy expanded in 1994 with the addition of 46 more rhesus macaques. All of the animals in the study were enr...er table, and 20 are on a calorie-restricted diet. rhesus macaques have an average life span of about 27 yea...es ranging from spiders to humans The Wisconsin rhesus macaque study, however, is likely to provide the m...

Transplant drug stimulates immune memory

...ristian Larsen, MD, PhD, director of the Emory Transplant Center and chair of the Department of Surgery, to show that rapamycin had similar effects in rhesus macaques infected with vaccinia virus as in mice. That research was conducted at Emory's Yerkes National Primate Research Center. Rapamycin, also c...

Press Releases on BPA Studies By-Pass Scientific Process

...n of Calcium Handling," Scott M. Belcher, PhD; and "Oral Exposure of Female rhesus Monkeys...," Frederick vom Saal, PhD. The statement can be attributed to S...evidence of health risks. "Most notably though, the study presented on rhesus monkeys appears to confirm that bisphenol A is efficiently converted after ...

Studies Report More Harmful Effects From BPA

...," said Steve Hentges, executive director of the Polycarbonate/BPA Global Group at the American Chemistry Council. "Most notably though, a study on rhesus monkeys appears to confirm that bisphenol A is efficiently converted after oral exposure to biologically inactive metabolites, which are then rapidly ...

Why Chimps, Monkeys Don't Develop Alzheimer's

... in live human brains, thus "lighting up" the plaques on positron-emission tomography (PET) scans. They used PIB in brain tissue from nine deceased rhesus monkeys, six deceased squirrel monkeys, three deceased chimpanzees, nine deceased humans with end-stage Alzheimer's and three deceased older but healt...

Germicide Might Guard Against HIV Infection

...thor Patrick M. Schlievert, a professor of biology at the University of Minnesota. In the new study, researchers tested the compound on five female rhesus macaques that were vaginally exposed to the monkey equivalent of the AIDS virus. The findings were published in the March 4 online issue of Nature . ...

OHSU vaccine research targets HIV in the slower, early stage of infection

...MV) programmed to express SIV proteins and trigger specialized effector memory T-cells to look for and attack SIV in its early stages. In total, 12 rhesus macaque monkeys at the Oregon National Primate Research Center were vaccinated using this method. When the animals were later infected with SIV, one-t...

Rhesus in Medical Technology

Novel Vaccine Approach Offers Hope in Fight Against HIV

... the scientists protected monkeys from infection by a virus closely related to HIV -- the simian immunodeficiency virus, or SIV -- that causes AIDS in rhesus monkeys. "We used a leapfrog strategy, bypassing the natural immune system response that was the target of all previous HIV and SIV vaccine candi...

U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant

...ed with or without the Vaxfectin(R) adjuvant and delivered by needle-free injection using the Biojector(R) 2000, were promising. Four of four (100%) rhesus macaques receiving the Vaxfectin(R)-formulated vaccine developed neutralizing antibodies to all four serotypes of dengue one month after the second in...

Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

...ncy of cethromycin as a potential treatment against bioterrorism pathogens: "Efficacy of Cethromycin Against a Lethal Inhalation Anthrax Challenge in rhesus Macaques" All antibiotic treated animals maintained normal hematologic parameters and remained abacteremic throughout the treatment period. All cethr...

Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

...ncy of cethromycin as a potential treatment against bioterrorism pathogens: "Efficacy of Cethromycin Against a Lethal Inhalation Anthrax Challenge in rhesus Macaques" All antibiotic treated animals maintained normal hematologic parameters and remained abacteremic throughout the treatment period. All cethr...

Advanced Life Sciences to Present Data on Selected Cethromycin Therapeutic Studies at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

...is and Therapeutics in Agents of Bioterrorism -- Poster: Poster B-2031: Efficacy of Cethromycin Against a Lethal Inhalation Anthrax Challenge in rhesus Macaques Wednesday, September 19, 12:15 p.m. Central Daylight Time, Hall D Poster Session 176: Macrolides, Ketolides, Bicyclolides and Quinolones ...

Inovio Biomedical's DNA Delivery Technology Significantly Enhances Potency of HIV DNA Vaccine

... technology. The paper, titled "Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques," summarized results of a research project lead by Michael A. Egan, Ph.D., a principle research scientist at Wyeth Vaccine Research. The scie...

Cleveland BioLabs Protectan CBLB502 Demonstrates Strong Survival Benefits as Mitigator Against Radiation-Induced Damage in Study

...sent results of the study at the 2007 American Association for Cancer Research (AACR) Annual Meeting, April 14-18, in Los Angeles, CA. In the study, rhesus monkeys were irradiated with 6.5 Gy of total body irradiation and injected intramuscularly with either a single dose of Protectan CBLB502 or a placebo...

Vaxfectin-formulated Measles DNA Vaccine Elicits Long-term Protection and Sterilizing Immunity in Nonhuman Primates

... impact on global measles disease and death rates." The study in juvenile rhesus macaques tested the protective efficacy of a bivalent DNA vaccine encoding ...ion. The vaccines were well-tolerated in all animals. The study in infant rhesus macaques tested only intradermal needle-and- syringe delivery of vaccine at...

Rhesus in Medical Dictionary

Semicircular canals

...s and the vestibule ... Semicircular canals . 16. ... 22. Semicircular canals . 23. Cochlear duct. MULTIPLE CHOICE. Choose ... ... (VOR) in rhesus monkeys following plugging of the lateral semicircular canals . ... Based on this hypothesis, semicircular canal plugging has been used to .....

Rh incompatibility

... jaundice of Rh incompatibility , measured by the level of ... (Redirected from Rh incompatibility ) Jump to: navigation, search ... HDN • rhesus E HDN) · Rh disease · Hydrops fetalis · Hyperbilirubinemia ... The jaundice of Rh incompatibility , measured by the level of bilirubin ...

Rh factor

... The term rhesus ( Rh ) blood group system refers to the 5 main rhesus antigens as well as the many other less frequent rhesus antigens. The terms...

Monocyte

...king. Mucosal Immunity. Laboratory of Host Defenses. Warren Strober, M.D. ... MONOCYTE , GRANULOCYTE, CALPROTECTIN, CLONE: 27E10, MAB ANTI-HUMAN, rhesus MONKEY ... ENDOTHELIAL- MONOCYTE ACTIVATING POLYPEPTIDE II (EMAP II), 20KD, CLONE: 546-2, ... Currently, monocyte -derived DCs are the most wide...

Enterotoxin

...gal serogroup)—are known to cause cholera. Pathogenic O1 and O139 V. ... Aerosolized staphylococcal enterotoxin B-induced pulmonary lesions in rhesus ... Staphylococcal enterotoxin B as a nonimmunological mast cell stimulus in ... ...

Blood typing

... ... have Type O negative blood . Type O negative blood is the preferred type for accident ... Each blood type is also grouped by its rhesus ... Blood type is inherited, just like eye color. ... Some people think blood type tells about personality. ... ... your blood group i...

Rhesus in Biological News

Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps

An international consortium of researchers has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee and human genomes. Published April 13 in a special section of the journal Science, the analysis reveals that the three primate species share about 93 percent ...

Genetic and environmental influences on alcohol consumption among rhesus monkeys

There is little doubt that alcohol-related disorders in humans are genetically based. The influence of environmental factors, however, remains unclear. Given that studies of humans are complicated by a multitude of cultural and day-to-day-living factors, researchers in the March issue of Alcohol...

Novel vaccine approach offers hope in fight against HIV

...fection, the scientists protected monkeys from infection by a virus closely related to HIVthe simian immunodeficiency virus, or SIVthat causes AIDS in rhesus monkeys. "We used a leapfrog strategy, bypassing the natural immune system response that was the target of all previous HIV and SIV vaccine candida...

Drugs needed to preserve eggs for reproduction need to be given in stages

...pid ones, say scientists who have developed a mathematical model that predicts optimal time for loading and unloading these drugs. Their studies in rhesus monkey eggs, which are very similar to human eggs, show that a two-step process of easing into and out of the drugs needed to help protect eggs at sub...

Beyond 'ooh-ooh, aah-aah'-- expert on monkey communication kicks off Darwin series, May 5

...shed in 1990 by the University of Chicago Press. Other species and research sites that are currently the focus of Seyfarth's research group include rhesus monkeys on Cayo Santiago, Puerto Rico; elephants in Sri Lanka; and geladas in Ethiopia. ...

Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes

...women respond to looming sounds sooner than their typically larger, stronger male counterparts -- though both groups perceive receding sounds equally. rhesus monkeys also spend less time looking at receding sounds than approaching sounds. "These reactions are influenced by evolutionary forces; it's a good t...

Potential new HIV drug may help patients not responding to treatment

...ill help HAART to work more effectively in these people. In the new study, researchers gave daily doses of a modified amino acid called D-1mT to 11 rhesus macaques infected with SIV. All of the macaques had been treated with ART for at least four months. Eight of the macaques had higher viral loads (reac...

Cutting-edge amfAR grants fight HIV/AIDS in the lab and on the phone

..., UT $125,000 Identifying cellular cofactors of rhesus monkey TRIM5-alpha: While the evolutionary struggl...ght differences in the protein TRIM5-alpha between rhesus monkeys and humans mean that the rhesus form of the protein can inhibit HIV infection whil...

How we see objects in depth: The brain's code for 3-D structure

...he Zanvyl Krieger Mind-Brain Institute at The Johns Hopkins University. In the study, Connor and a postdoctoral fellow, Yukako Yamane, trained two rhesus monkeys to look at a computer monitor while 3-D pictures of objects were flashed on the screen. At the same time, the researchers recorded electrical ...

Parkinson's Disease Foundation announces award of $150,000

...tical debates associated with using embryonic stem cells. Dr. Zhang's laboratory will examine the potential of iPS cells by reverting skin cells of rhesus monkeys into iPS cells and directing the cells to become dopamine neurons. Next, Dr. Emborg and her colleagues will insert the dopamine neurons produ...

Rhesus in Biological Technology

GenOdyssee Receives Broad Product Applications Protection in EU for Founding Natural Evolution Technology

... replicon assay without significantly increased toxicity as demonstrated in rhesus Monkeys compared to standards of care IFN alpha 2 molecules. GEA007.1 produ...aintained in IFN alpha 2 treated cells. - Similar safety pharmacology in rhesus monkeys (Macaca mulatta) to IFN alpha 2. - Importantly, GEA007.1 is a na...

Vaxfectin(R)-formulated Measles DNA Vaccine Could Address Unmet Need for Infants

...utralizing antibodies in juvenile (1 - 2 year old) rhesus macaques confirmed by complete protection followin...that were similar to those previously reported for rhesus macaques after immunization with the currently mar...fusion proteins protects juvenile and infant rhesus macaques from measles. Clin Vaccine Immunol 2008; ...

New digs for UW AIDS researchers

... The lab's major emphasis is on vaccine development, but it also has an interest in transmission and pathogenesis. The experiments are done with rhesus macaque monkeys under the auspices of the UW National Primate Research Center . Finding an AIDS vaccine is proving to be a much harder nut to crac...

Professor's anti-aging study draws national attention

...has worked for the last two decades to see if he can extend the lifespan of rhesus monkeys was featured in the MIT Technology Review's March/April issue. R...rly even now to tell whether a diet low in calories has really extended the rhesus monkey's lives, because they live so long normally. What Weindruch has f...

A brief timeline of the stem cell debate

...ents in the controversy so far: November 1995: Researchers at the University of Wisconsin isolate the first embryonic stem cells in primates -- rhesus macaque monkeys. The research shows it's possible to derive embryonic stem cells from primates, including humans. January 1998: Scientist and ent...

Deliver siRNAs Into Primary Cells

...ic vascular smooth muscle cells (BAVSMC), bovine adrenal microvascular endothelial cells (BAMEC), mouse embryo fibroblast (MEF), rhesus monkey stem cells (RMSC), bovine lung microvascular endothelial cells (BLMVEC) are shown in blue. Hard-to-transfect cell lines...

Rhesus in Biological Products

StemSep Rhesus T Cell Purging, 2 mL Kit from StemCell Technologies, Inc.

Description: This depletion cocktail is tailored to efficiently deplete T (CD3+CD4+CD8+) cells from suspensions of non-human primate (Rhesus monkey) cells. Cells are separated using the StemSep (or compatible 0.5 Tesla) immunomagnetic negative selection system, achieving a 2.6 Log depletion of T cells....
Company:StemCell Technologies, Inc.

StemSep Rhesus CD4+ T Cells, 2 mL Kit from StemCell Technologies, Inc.

Description: This depletion cocktail is tailored to highly enrich CD4+ T cells from suspensions of non-human primate (Rhesus monkey) cells. Cells are separated using the StemSep compatible 0.5 Tesla) immunomagnetic negative selection system. The CD4+ T cell content of the enriched fraction typically ranges from...
Company:StemCell Technologies, Inc.

Rhesus Serum from Innovative Research

Description:... rhesus Serum • rhesus serum is collected from fasted rhesus monkeys of mixed sex and 5-7 years of age. Avail...
Company:Innovative Research

Rhesus Monkey IFN-Alpha from Cell Sciences

Description:... Recombinant rhesus Monkey IFN-Alpha...
Company:Cell Sciences

Rhesus Macaque IFN-alpha from R&D Systems

Description:... Recombinant rhesus Macaque IFN-alpha...
Company:R&D Systems

Rhesus Monkey IFN Alpha from PBL InterferonSource

Description:... Recombinant rhesus Monkey IFN Alpha Activity: 2.9 x 10 8 u/mg...
Company:PBL InterferonSource

15(S)-15-methyl Prostaglandin F2alpha from Cayman Chemical

Description:...scularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys....
Company:Cayman Chemical

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Rhesus in Biological Definition

Cloning

...ed on several species: (in chronological order) frogs : (1962) Unsuccessful carp : (1963) Successfully cloned sheep : (1996) Dolly rhesus monkey : Tetra (female, January 2000) pig : 5 Scottish PPL piglets (March 2000), Xena (female, August 2000) gaur : Noah (male, January 20...

Genome project

...mouse Rattus norvegicus Laboratory rat Chimp (Pan troglidans) rhesus Macaque rhesus monkey Gallus gallus Chicken Macropus eugenii Kangaroo Feli...

Blood type

... showTocToggle("show","hide") 1 ABO 2 rhesus 3 Inheritance 3.1 ABO 3.2 rhesus 4 Rare phenotypes 4.1 Bombay phenot... for his work in discovering ABO blood types. rhesus Another characteristic of blood is ...

Rhesus in Biological Dictionary

Transgenic

...e: Transgenic Core Facility ... The Roth lab developed transgenic mice in which activity of specific neuronal ... [ANDi, the first transgenic rhesus monkey, carries the gene for a green ... cumbersome technique is not likely to lead to transgenic humans, green or otherwise. ... This is a bri...

Rhesus factor

... The term rhesus (Rh) blood group system refers to the 5 main rhesus antigens as well as the many other less frequent rhesus antigens. The terms ...