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Retinopathy in Medical News

Insmed and Premacure Announce European Orphan Designation for IPLEX(TM) in Retinopathy of Prematurity in Infants

RICHMOND, Va., Jan. 21 /PRNewswire-FirstCall/ -- Insmed Inc. (Nasdaq: INSM ), a developer of follow-on biologics and biopharmaceuticals, and Premacure AB, a biopharmaceutical company dedicated to the development of, diagnosis and prevention of complications in neonates due to premature birth, t...

Genentech/Roche's Lucentis and Eli Lilly's Ruboxistaurin Will Drive the Diabetic Retinopathy and Nephropathy Drug Markets

Longer Term Growth of Diabetic Neuropathy Market Will Be Driven by Launches of Disease-Modifying Therapies, According to a New Report from Decision Resources WALTHAM, Mass., Sept. 24 /PRNewswire/ -- Decision Resources, one of the world's leading research and advis...

Because of Its Ability to Generate Higher Total Sales in the United States and Europe, Lucentis Will Earn Clinical Gold Standard Status by 2011 for the Treatment of Diabetic Retinopathy

A Drug with Superior Efficacy to Avastin at Improving Visual Acuity When Used with Laser Photocoagulation Would Earn a 20 Percent Patient Share, According to a New Report from Decision Resources WALTHAM, Mass., June 26 /PRNewswire/ -- Decision Resources, one of the world's leading ...

Omega-3 Fattyacids Keeps Retinopathy at Bay

Omega-3 polyunsaturated fatty acids protect against the development and progression of retinopathy, a deterioration of the retina, in mice. This is the major finding of a study that appears in the journal Nature Medicine. The study was a collaborative effort by researchers at Childrens Hospit...

Marijuana Compound Offers Hope In Diabetic Retinopathy Prevention

A compound in marijuana has been found to offer protection against diabetic retinopathy, an eye related complication, seen in diabetic individuals// Retina represents a light sensitive tissue behind the eye. Diabetes damages tiny blood vessels in the retina, eventually leading to blindness. Diabeti...

knowledge of proliferative sickle cell retinopathy can help Prevent eye trauma

Sickle cell disease is an inherited blood disorder that affects the hemoglobin protein found in red blood cells. Visual loss has been reported in 10- 20% of eyes in patients with this disease, a high figure that // may reflect ascertainment bias towards detecting patients with symptoms. Proliferat...

Diabetic retinopathy in pre-diabetes conditions

Researchers have found the occurrence diabetic retinopathy in a number of people// with pre-diabetic conditions for diabetes type 2. Diabetes type 2 happens when body cannot use its own insulin to control blood sugar. As this happens the body becomes unable to produce enough insulin to overcom...

Vision Loss Due To Diabetic Retinopathy a Major Cause Of Concern

Diabetic retinopathy is a major cause of vision loss among adults. About 22 percent to 36 percent of all diabetics // in the United States and Australia suffer from the condition. Vision impairment caused by the disease often leads to dependency in activities of daily living, social isolation, a...

Insulin Therapy Shown to Treat Early Experimental Diabetic Retinopathy

Researchers will present study results that indicate that subconjunctivally delivered insulin ameliorates degenerative and inflammatory responses in diabetic rat retinas at the Association for Research in Vision and Ophthalmology (ARVO) 2007 Annual Meeting in Fort Lauderdale, Fla. The presentation...

History of Migraines Linked to Increased Risk of Retinopathy

Researchers at the University of North Carolina, Chapel Hill, have found out that middle-aged people with a history of migraine and other headaches are at a higher risk of retinopathy than others. Retinopathy is described as damage to the retina of the eye that can lead to severe vision p...

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Retinopathy in Medical Technology

Breaking Multi-Center Study: Masimo SET Pulse Oximetry Technology Shown to Significantly Lower Instances of Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants

Study released at the Pediatric Academic Societies' Annual Meeting This Month in Toronto Shows That Switching to Masimo SET Pulse Oximetry Technology Can Reduce the Risk Associated with ROP by 40% IRVINE, Calif., May 30, 2007 /PRNewswire/ -- Masimo, the inventor of Pulse CO-Oximetry and Read-Throu...

June 2009 Mayo Clinic Women's HealthSource Highlights Summer Skin Problems, Low Vision and Pilates

...lty reading the small print that can accompany aging. Low vision is caused by eye diseases such as macular degeneration, glaucoma, cataracts, diabetic retinopathy or retinitis pigmentosa. Vision loss can be mild to severe. Patients should work with a low-vision specialist to determine the best tools and ho...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

...A] injection) versus NPH insulin on progression of retinopathy in patients with type 2 diabetes, published on-lin....1007/s00125-009-1415-7) showed similar effects on retinopathy and overall safety in the two treatment groups. Th...ver reported using insulin glargine. Diabetic retinopathy is a major cause of blindness in patients with dia...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

...uticals Paloma Pharmaceuticals, Inc. is an early stage drug development company focusing on cancer, ocular diseases (macular degeneration, diabetic retinopathy and proliferative vitreoretinopathy), arthritis, fibrotic diseases (pulmonary fibrosis), viral (HIV) and skin diseases (psoriasis and atopic dermatiti...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

...s included hallucinations. bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cy...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...nitis and sarcoidosis), colitis (ulcerative and hemorrhagic/ischemic colitis), pancreatitis, and ophthalmologic disorders (decrease or loss of vision, retinopathy including macular edema and retinal thrombosis/hemorrhages, optic neuritis and papilledema). Adverse reactions reported during post-approval us...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...nitis and sarcoidosis), colitis (ulcerative and hemorrhagic/ischemic colitis), pancreatitis, and ophthalmologic disorders (decrease or loss of vision, retinopathy including macular edema and retinal thrombosis/hemorrhages, optic neuritis and papilledema). Adverse reactions reported during post-approval use of ...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...s included hallucinations. bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton wool spots, papilledema, ischemic and hemorrhagic cerebrovascular events, bone marrow toxicity (cy...

Alimera Sciences' Iluvien(TM) Phase 3 Studies for DME Pass Final DSMB Review Prior to October Readout

...es. Over time, all diabetics are at risk of developing some form of diabetic retinopathy, an ophthalmic condition of diabetes. In the U.S., diabetic retinopathy causes approximately 12,000 to 24,000 new cases of blindness each year, making diabetes the leading cause of new cases of blindness in adults aged 20 ...

Scientists Discover a Role for the Growth Factor TGF-beta in Maintaining Health of Retinal Blood Vessels

... These findings, published in the April 2 issue of PLoS ONE, may have an important impact on the prevention and treatment of diseases such as diabetic retinopathy and macular degeneration. "These results are significant because they add to our understanding of the molecules that help to maintain blood vess...
Retinopathy in Medical Products

Dyna View 156°

Description:...ata in both premature infants and adult patients. Featuring a minified housing and reduced 8.5mm contact element, the Volk DynaView 156 revolutionizes retinopathy of prematurity surgery and is an absolute requirement for lens sparing vitrectomies in ROP. It allows extension of instruments in the pediatric retrol...
Company:Volk Optical, Inc.

Quad Pediatric

Description:... This specially adapted QuadrAspheric design with 10mm diameter contact surface is ideal for diagnosis and management of retinopathy of prematurety (ROP) and other infant conditions. It has been developed to aid the practitioner in the diagnosis and treatment of the pediatric patien...
Company:Volk Optical, Inc.

Area Centralis®

Description:...ating subretinal neovascularization and changes from macular degeneration, retinal vascular occlusions, diabetic macular edema, proliferative diabetic retinopathy and other retinal conditions. It is ideal for focal laser treatment of these conditions providing excellent magnification combined with a good field o...
Company:Volk Optical, Inc.

Multicolor Laser Photocoagulator MC-300

Description:... NIDEK MC-300 is designed to treat a diverse range of patients suffering from such conditions as age-related macular degeneration, glaucoma, diabetic retinopathy and retinal diseases to meet all the clinical needs of retinal specialists....
Company:NIDEK, Inc.

RetCam II Wide-Field Digital Pediatric Retinal Imaging System

Description:... Angiography option. The RetCam II is the pediatric imaging tool of choice in the OR, NICU and PICU for documenting and managing Retinoblastoma, retinopathy of Prematurity, Shaken Baby Syndrome and other pediatric eye diseases....
Company:Clarity Medical Systems, Inc.

EyeCap RI Image Capture and Management System

Description:...-mydriatic fundus cameras. It provides an ideal method of documenting large volumes of images often acquired in screening for disease such as diabetic retinopathy and glaucoma. Included in EyeCap's database is a user-deniable grading form and report writer, which allow assessment of images (grading) and the prod...
Company:Haag-Streit USA, Inc.

Topcon Telemedicine System

Description:...e latest advances in digital imaging software with Topcons Non-Mydriatic retinal camera allowing a technician to perform highly accurate color-digital retinopathy screenings within a comfortable and easy to use platform. The TRC-NW6S comes with Topcons MOSAIC 2000 software, which allows a composite image to be q...
Company:Topcon America Corporation

TRC-NW100

Description:...n pixel image provides excellent details of the retinal surface for all types of diagnostic requirements from disc evaluation for glaucoma to diabetic retinopathy evaluation. The simplest way to provide filmless, instant review, digital filing and digital referral of color retinal images....
Company:Topcon America Corporation

TRC-NW200 Non-Mydriatic Retinal Camera

Features:...ls to provide superior detail of the retinal surface for all types of diagnostic needs, from disc evaluation for glaucoma to hypertension and diabetic retinopathy screening. Smaller Pupil Size Allows high quality images with an even smaller 3.7mm pupil. A real benefit when managing patients on medicat...
Company:Topcon America Corporation

Novus Varia Three Color Photocoagulator

Features:... may be focused deeper in the choroid Treatment for ocular melanoma retinopathy of Prematurity Yellow Wavelength: Better penetration through n... Green Wavelength: Clinically proven Proliferative Diabetic retinopathy Retinal Vein Oclusion ...
Company:Lumenis Inc.
Retinopathy in Medical Definition

Pathology

...hy , ketoacidosis , nephropathy , neuropathy , retinopathy ) - Hypoglycemia - Hyperinsulinism - Zollinge...inal detachment - Retinoschisis - Hypertensive retinopathy - Diabetic retinopathy - ...
Retinopathy in Medical Dictionary

Retinopathy

Retinopathy is a general term that refers to some form of non-inflammatory damage to the retina of the eye. Frequently, retinopathy is an ocular manifestation of systemic disease. Diabetic retinopathy is retinopathy caused by complications of diabetes mellitus, which can eventua...

Diabetic retinopathy

Diabetic retinopathy is retinopathy caused by complications of diabetes mellitus, which can eventually lead to blindness. It is an ocular manifestation of systemic disease which affects up to 80% of all patients who have had... Diabetic retinopathy — Comprehensive overview c...

Retinitis pigmentosa

... ... Patients with retinitis pigmentosa (RP) may present with varying symptoms. ... Retinitis Pigmentosa . Retinal Detachment. Hypertensive retinopathy ... ...

Prematurity

... premature infant. Because it is by far the... retinopathy of prematurity (ROP), previously known as retrol...ces for the public and professionals. ... What is retinopathy of prematurity ? How many infants have ROP? What causes ROP? ... ROPARD Association for retinopathy of Prematurity and Related Retinal Diseases ......

Detached retina

...on loss. Vitrectomy and vitreoretinal eye surgery can help treat retinal detachments ... Detached retina . Diabetic retinopathy. Diabetic retinopathy - eye doctor Q&A ... What is Detached Retina ? ... of the retina becomes separated from the choroid this detached part loses its ....
Retinopathy in Biological News

Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment

NEW YORK, Jan. 21, 2009 Researchers from Joslin Diabetes Center, Boston, and ActiveSite Pharmaceuticals, Inc., San Francisco, announced today that they have demonstrated that a specific inhibitor of the protease plasma kallikrein, ASP-440, developed by ActiveSite Pharmaceuticals, may provide a ne...

Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice

SALT LAKE CITY Two major eye diseases and leading causes of blindnessage-related macular degeneration and diabetic retinopathycan be reversed or even prevented by drugs that activate a protein found in blood vessel cells, researchers at the University of Utah School of Medicine and several other i...

Natural compound stops retinopathy

OKLAHOMA CITY Researchers at the University of Oklahoma Health Sciences Center have found a way to use a natural compound to stop one of the leading causes of blindness in the United States. The research appears online this month in the journal Diabetes , a publication of the American Diabetes A...

ORNL, Southern Cal set sights on preventing blindness

...vide oxygen to retinal tissue being deprived of oxygen because of restricted blood flow. This condition occurs predominantly in patients with diabetic retinopathy ( http://www.nei.nih.gov/health/diabetic/retinopathy.asp ), which affects an estimated 5.5 million people each year. Elias Greenbaum of the Departm...

Collegiate Inventors Competition recognizes top student inventors

... of Medicine (Advisor: Jun Liu) Identification of the Antifungal Drug Itraconazole as an Antiangiogenic Agent Useful for Treating Cancer and Diabetic retinopathy Potential to treat cancer and common issues associated with diabetes with Itraconazole, a drug typically used to treat fungal infections. Nathan ...

American Chemical Society’s Weekly PressPac -- May 7, 2008

... Identifying abnormal protein levels in diabetic retinopathy Journal of Proteome Research Researchers in...occur inside the eyes of individuals with diabetic retinopathy (DR) a leading cause of vision loss and blindness...the Vitreous Proteome in Diabetes without Diabetic retinopathy and Diabetes with Proliferative Diabetic...

Scientists uncover the potential to control adult stem cells

... therapies, a better knowledge of how blood vessels develop is crucial to understanding and treating a huge range of diseases such as cancer, diabetic retinopathy and cardiovascular disease. Professor Kielty said: What we have shown is that adult stem cells respond in particular ways to some of the chemical ...

Protein controls blood vessel formation, offers new drug target

...ew blood vessels to repair damaged tissue. But sometimes too much growth causes problems, as when new blood vessels in the eyes leak, causing diabetic retinopathy and blindness if not treated. A protein called CIB1 discovered by researchers at the University of North Carolina at Chapel Hill School of Medicine...

'Twinkle after-effect' can help retinal patients detect vision loss quickly and cheaply

...This will be particularly helpful with patients who have glaucoma, diabetic retinopathy or macular degeneration where early detection of changes in vision can impa...s innate process can mask the effects of serious disorders such as diabetic retinopathy and glaucoma and keep sufferers from seeking help until the vision loss is ...

'Molecular assassin' targets disease gene

... in the July issue of Nature Biotechnology. Certain types of skin cancers and blindness due to age-related macular degeneration (AMD) and diabetic retinopathy are likely to be among the first uses for the drug. AMD is the most common cause of blindness in Australia (Macular Degeneration Foundation). The e...
Retinopathy in Biological Technology

R-Tech Ueno Notifies R&D Items

...reases in patients with diabetes mellitus. We intend to proceed with the development of this substance to be indicated for diabetic cataract, diabetic retinopathy and age-related macular degeneration. 3. Development code RU-10 (eye diseases) Dry eye is targeted for development of the drug that cont...

Sanofi-aventis Announces Second Quarter 2009 Results

...lts of a 5-year study of Lantus ((R)) versus NPH insulin on progression of retinopathy in patients with type 2 diabetes. These results demonstrated that the two treatments showed similar effects on the progression of retinopathy and provided similar overall safety. There was no observable difference in ...

Preclinical Data From Amgen's Oncology Pipeline to be Presented at AACR

...ts from a number of clinical programs become available." Selected Abstracts of Interest -- Assessment of angiogenesis inhibitors in the retinopathy of prematurity model in mice Overview: Examined the inhibition of the VEGF/VEGFR pathway with AMG 273 and the inhibition of th...

Insmed Announces Fourth Quarter and Full-Year 2008 Financial Results

...utside of Italy; The European Medicines Agency (EMEA) granted Premacure AB orphan designation for Insmed's IPLEX(TM) for the prevention of retinopathy of prematurity (ROP) in neonates of less than 32 weeks of gestational age. Premacure AB intends to initiate a phase 2 multicenter trial for IPLEX(TM)...

Insmed Announces Financial Results for Third Quarter and Nine-Months Ended September 30, 2008

...F-I levels into the normal range in significantly premature infants. Premacure is developing IPLEX(TM) as a potential treatment for retinopathy of Prematurity ("ROP") via a Material Transfer Agreement with Insmed. Based in part on the results of this study, Premacure intends...

Collegiate Inventors Competition(R) Recognizes Top Student Inventors

...of Medicine (Advisor: Jun Liu) Identification of the Antifungal Drug Itraconazole as an Antiangiogenic Agent Useful for Treating Cancer and Diabetic retinopathy - Potential to treat cancer and common issues associated with diabetes with Itraconazole, a drug typically used to treat fungal infections. Nathan C...

Insmed and Premacure Cite Study Results Demonstrating Potential Effectiveness of IPLEX(TM) in Preventing Blindness in Premature Infants

...macure to Initiate Phase II Trial for IPLEX(TM) in retinopathy of Prematurity - RICHMOND, Va. and UPPSALA, Swed... developing IPLEX(TM) as a potential treatment for retinopathy of Prematurity (ROP) via a Material Transfer Agree...he first of several indications to be developed is retinopathy of Prematurity (ROP) a retinal disease being one o...

Carilion Clinic Invests in Sight Saving Technology to Improve Patient Care: Carilion Clinic Teams Up with Retasure

...o half of these patients do not have regular eye exams. Being assessed for retinopathy through their PCP will undoubtedly lead to earlier detection -- and prevent...risk of diabetic retinopathy. The National Eye Institute indicates diabetic retinopathy is the leading cause of blindness among working age American adults. More t...

ThromboGenics N.V. - Business Update

...sed to treat a number of important back of the eye diseases. This is because common eye diseases such as age-related macular degeneration and diabetic retinopathy are caused by uncontrolled blood vessel growth, which could be halted using TB-403. The Remainder of 2008 ThromboGenics expects to deliver a numbe...

Ocular Biopharmaceutical Company Charlesson Announces $1.6MM in New Funding and Upcoming Presentations at The Association for Research in Vision and Ophthalmology

... NIH to develop CLT-004 for treating AMD, Diabetic retinopathy (DR), and Diabetic Macular Edema (DME). These fund...lead compounds," said Mr. Moradi. About Diabetic retinopathy and Macular Degeneration Diabetic retinopathy is the one of the most common complication of Diab...
Retinopathy in Biological Definition

Diabetes mellitus

...d glucose control, but large vessel disease is unaffected by tight blood glucose control. Small vessel disease complications: proliferative retinopathy which can lead to blindness ; peripheral neuropathy which, particularly when combined with damaged blood vessesls, can lead to foot ulcers, an...

Eye

...itis Corrective lenses Floaters Glaucoma Hyperopia Keratoconus Myopia Nyctalopia Presbyopia Retinal detachment retinopathy Scotoma Snow blindness Strabismus Uveitis See also The human eye is sometimes metaphorically called "the window to ...

Insulin

...normal'. The chronic diabetic complications include cerebrovascular accidents (CVA or stroke), heart attack, blindness (from proliferative diabetic retinopathy ), toehr vascular damage, nerve damage from diabetic neuropathy , or kidney failure from diabetic nephropathy . These studies have demonstrated bey...
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