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Retinoblastoma in Medical News

Risk Of Soft Tissue Sarcomas In Hereditary Retinoblastoma Survivors

A study by Ruth A. Kleinerman and his colleagues quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds that// this risk persists for decades after the original retinoblastoma diagnosis. The findings published in the January 3 ...

Barking Up the Right Tree to Cure Retinoblastoma

Chicago – U.S researchers seem to have tapped nature, in the form of an extract from the bark of a South American tree, as a possible cure for a notorious type of childhood// eye cancer, called retinoblastoma. Retinoblastoma accounts for nearly 3% of all cancers in children, affecting about one in ...

Ongoing Study Shows That Endovascular Therapy is Associated With High Cure Rate for Childhood Eye Cancer

... Day Procedure May Transform Treatment Approach to retinoblastoma BOCA RATON, Fla., July 28 /PRNewswire-USNe...as chemosurgery, would produce better outcomes for retinoblastoma patients, including preserving the eye and vision ...nique. Of this number, all suffered from advanced retinoblastoma and were candidates for removal of the eye. Addit...

Louisiana Optometrists Partner With Sens. Landrieu and Vitter, U.S. House Leaders in Improving Infant Eye and Vision Care

...optometrists nationwide volunteer their time to provide assessments to babies in their communities. The majority of vision problems detected included retinoblastoma (eye cancer), severe hyperopia (farsightedness), myopia (nearsightedness), congenital glaucoma and congenital cataract. "As a parent, one of my...

Make Sure Your Baby is Seeing the Most Important Things in His World

...pairment include: Premature birth, low birth weight, or oxygen used following birth Family history of eye diseases such as retinoblastoma (eye cancer), congenital cataracts, or metabolic or genetic disease Drug or alcohol use during pregnancy Sexually transmitted disease...

St. Louis Metro Area Optometrists Partner With Sen. Bond; U.S. House Leaders in Improving Infant Eye and Vision Care

...optometrists nationwide volunteer their time to provide assessments to babies in their communities. The majority of vision problems detected included retinoblastoma (eye cancer), severe hyperopia (farsightedness), myopia (nearsightedness), congenital glaucoma and congenital cataract. "As a parent, one of my b...

Seattle and Tacoma-Area Optometrists Partner With Sen. Murray in Improving Infant Eye and Vision Care

...optometrists nationwide volunteer their time to provide assessments to babies in their communities. The majority of vision problems detected included retinoblastoma (eye cancer), severe hyperopia (farsightedness), myopia (nearsightedness), congenital glaucoma and congenital cataract. "As a parent, one of my b...

West Virginia Optometrists Partner With Sens. Byrd and Rockefeller, U.S. House Leaders in Improving Infant Eye and Vision Care

... optometrists nationwide volunteer their time to provide assessments to babies in their communities. The majority of vision problems detected included retinoblastoma (eye cancer), severe hyperopia (farsightedness), myopia (nearsightedness), congenital glaucoma and congenital cataract. "As a parent, one of my b...

Sen. Durbin and U.S. House Leaders Support Chicago-Area Optometrists in Improving Infant Eye and Vision Care Through the InfantSEE(R) Program

... optometrists nationwide volunteer their time to provide assessments to babies in their communities. The majority of vision problems detected included retinoblastoma (eye cancer), severe hyperopia (farsightedness), myopia (nearsightedness), congenital glaucoma and congenital cataract. "As a parent, one of my b...

Also in the April 7 JNCI

...ause of Death in Long-Term Survivors of Hereditary retinoblastoma Long-term survivors of hereditary retinoblastoma are at an increased risk of death due to a second cancer, according to a large cohort study. retinoblastoma is a very rare cancer of the eye that affects appr...
Retinoblastoma in Medical Technology

New Localized Cancer Treatment for Advanced Retinoblastoma Saves Children From Having Eyes Removed, Restores Vision in Some Cases

Interventional Radiologist Delivers Chemo Drug Directly to Eye via Ophthalmic Artery WASHINGTON, March 17 /PRNewswire-USNewswire/ -- A new interventional radiology treatment successfully treats advanced retinoblastoma -- a deadly, inherited cancer of one or both eyes in children -- and oft...

Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases

...seases, according to a new report by A. Linn Murphree, M.D, director of the retinoblastoma Program in The Vision Center at Children's Hospital Los Angeles. Dr. Murphr...lose to the brain. "When we administer chemotherapy to an infant for retinoblastoma at The Vision Center, it is expensive and puts a great strain on the family...

St. Jude Defines Eye Cancer Gene's Role in Retinal Development

...in the United States annually. "The determination of N-myc target genes during retinal development may also contribute to the current understanding of retinoblastoma progression," he said. In the course of their study, the researchers discovered that N-myc is not involved in regulating cell survival or neuronal...

St. Jude Identifies the Specific Cell That Causes Eye Cancer, Disproving Long-Held Theory

...iate importance of the St. Jude finding is that it unexpectedly showed that retinoblastoma can arise from fully matured nerves in the retina called horizontal interne...very that fully differentiated horizontal interneurons can multiply to form retinoblastoma also challenges the established scientific belief that cancer cells are mos...
Retinoblastoma in Medical Definition

Ocular oncology

... benign like dermoid cysts , or malignant like rhabdomyosarcoma and retinoblastoma . The most common eyelid tumor is called basal cell carcinoma . This tum... . The most common malignant intraocular tumor in children is called retinoblastoma . Affecting approximately 325 children per year in North America, early det...
Retinoblastoma in Medical Dictionary

Retinoblastoma

Retinoblastoma (Rb) is a rapidly developing cancer which develops in the cells of the retina, the light detecting tissue of the eye . In the developed world, Rb has one of the best cure rates of all childhood cancers... Click here for the Parent's Guide to Understanding Retinoblastoma ...

Hyphema

...DUCTION Traumatic hyphema , or blood in the anterior chamber, is a common ... Traumatic hyphema : Clinical features and management. Overview of retinoblastoma ... © Help for sleepless parents. Encyclopedia Index H hyphema | Search ... hyphema . Hyphema (high-FEE-ma) is the condition of blood in t...
Retinoblastoma in Biological News

Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors

A study in the January 3 issue of the Journal of the National Cancer Institute quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds that this risk persists for decades after the original retinoblastoma diagnosis. The findings em...

International team reveals first prognosticator of survival in aggressive cancer

...ngs show that a reduction in the expression of pRb2/p130 can mean a higher risk of recurrence and death from STSs. The gene pRb2/p130, a member of the retinoblastoma family of genes, regulates a portion of the cell cycle. Clinicians have long sought a prognostic test for the disease, which can be highly aggressi...

St. Jude defines eye cancer gene's role in retinal development

... in the United States annually. The determination of N-myc target genes during retinal development may also contribute to the current understanding of retinoblastoma progression, he said. In the course of their study, the researchers discovered that N-myc is not involved in regulating cell survival or neuronal ...

St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory

...al Neurobiology, is the reports senior author. retinoblastoma arises in the retinathe multi-layered, membrane li.... Jude finding is that it unexpectedly showed that retinoblastoma can arise from fully matured nerves in the retina ...iated horizontal interneurons can multiply to form retinoblastoma also challenges the established scientific belief ...

UC health news: molecular pathway may predict chemotherapy effectiveness

...ts will benefit from chemotherapy drugs, according to new research from a multidisciplinary team at the University of Cincinnati (UC). Known as the retinoblastoma (RB) tumor suppressor, this fundamental molecule regulates cell proliferation in the body. Research has shown that the RB pathway is either entirely i...

Tumor-suppressor gene is critical for placenta development

...nt and oxygen exchange between a mother and her fetus during pregnancy, and perhaps in miscarriages. Those conclusions come from a new study of the retinoblastoma (Rb) gene in mice. In humans, this gene, when mutated, raises the risk of a rare cancer of the eye called retinoblastoma. Two decades ago, it was iden...

St. Jude announces breakthrough in eye cancer treatment

... new, locally applied treatment for the eye cancer retinoblastoma that not only greatly reduces the size of the tumo...rs in the Nov. 2 issue of the journal Nature. retinoblastoma occurs in about 5,000 young children worldwide eac...mpler, more effective and less-toxic treatment for retinoblastoma that would eliminate the need for the current, com...

Why mice don't get cancer of the retina

... are more susceptible to developing the eye cancer retinoblastoma than mice because, unlike humans, mice can compens..., explains why humans with a defective copy of the retinoblastoma gene RB1 are at high risk of developing cancer of ...e Center in Memphis, studied the expression of the retinoblastoma proteins Rb (RB1 in humans), p107 and p130 through...

Texas scientists discover how a hepatitis C protein promotes liver cancer

...e UTMB group discovered that the tumor-suppressing retinoblastoma protein is present at markedly reduced levels in c...ntify a protein known as NS5B that attaches to the retinoblastoma protein, a critical tumor suppressor, and accelera...n said. He continued: "The way NS5B docks with the retinoblastoma protein is biochemically almost identical to the w...

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered

...n--called EBNA3C (for EBV nuclear antigen)--mediates the degradation of the retinoblastoma protein, an important molecular brake for cell proliferation. Erle S. Rob... last week in the Proceedings of the National Academy of Sciences. The retinoblastoma protein (Rb) is a major regulator of several genes in charge of cell prolif...
Retinoblastoma in Biological Technology

Unraveling the genetic picture of lung cancer

...n. This approach enabled the BCM researchers to identify mutations with unprecedented sensitivity. As a result, genes such as neurofibromatosis 1 and retinoblastoma 1, and several more that had been previously associated with other cancers, were discovered to be involved in this type of lung cancer. "Our abilit...

Large-scale genetic study sheds new light on lung cancer

...lay a role in ataxia telangiectasia, which is a rare inherited neurological disorder of childhood, and in various types of leukemia and lymphoma. retinoblastoma 1 (RB1). Past research has tied RB1 mutations to retinoblastoma, a relatively uncommon type of childhood cancer that originates in the eye's retina. ...

McGill University Purchases GenVault's Personal Archive System to Manage Rare Cancer Samples

...t technology will be a critical component of the Laboratory's research in determining the mechanisms underlying eye cancers such as uveal melanoma and retinoblastoma and for developing new approaches for treatment. These eye cancers are particularly devastating with a high percentage of patients developing metastat...

Using the TripleMaster PCR System for Robust Amplification of GC-Rich DNA Templates

...4.0 mM Mg2+) was used for the apolipoprotein E and retinoblastoma gene reactions due to the size of the t...conditions for the apolipoprotein E and retinoblastoma targets. Reactions were then set up in parallel to...equences Human retinoblastoma gene (RB) 180 bp 75% ...
Retinoblastoma in Biological Products

Anti-Heat Shock Protein 75 (hsp75) (TRAP-1) Ab-2 Monoclonal Antibody, Unconjugated from Lab Vision

Description:...dicating that TRAP-1 has functions that are distinct from those of hsp90. It was also found that TRAP-1 had a biochemical activity to refold denatured retinoblastoma protein (Rb) into its native conformation. Species Reactivity: Human. Others-not tested....
Company:Lab Vision
Retinoblastoma in Biological Definition

Cancer

...ve survival for infants is very good for neuroblastoma, Wilms' tumor and retinoblastoma , but not for most other types of cancer. Childhood cancers include, from ...y occurring to least: neuroblastoma , leukemia , central nervous system, retinoblastoma , Wilms' tumor , germ cell, soft tissue sarcomas , hepatic, lymphomas (...
Retinoblastoma in Biological Dictionary

Gene family

... Ontology ... Human Apoptosis TRC lentiviral shRNA gene family -Glycerol. call. call. Search: ... For Low Income Families . Healthy Families . retinoblastoma Gene . Human Resources Jobs ... Gene Expression. Everything you need to know about RNAi and gene ... Cytokines & Cells Online Pathfinder E...

Gene families

.... Higher levels of gene or protein classifica- tion, such as families , subfamilies, and su ... For Low Income Families . Healthy Families . retinoblastoma Gene . Human Resources Jobs ... Gene Expression. Everything you need to know about RNAi and gene ... Gene Families and Pathways. Focused s...
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