UF scientists program blood stem cells to become vision cells
... GAINESVILLE, Fla. University of Florida researchers were able to program bone marrow stem cells to repair damaged retinas
in mice, suggesting a potential treatment for one of the most common causes of vision loss in older people.
The success in repairing a damaged laye...
Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration
...Effect' rather than a Sympathetic Ophthalmic effect which is very rare. Stemedica discovered the presence of these endogenous RPE stem cells in adult retinas
several years ago. This original research demonstrated that these RPE stem cells acquired embryonic markers (Nanog and Oct-4) in adult humans.
Growth factor TGF-B helps maintain health of retinal blood vessels
...s that produces large quantities of soluble endoglin, a protein that would circulate, and then bind to and inhibit TGF-β. When they examined the retinas
of treated mice, the team found clear evidence that retinal blood vessels were losing their integrity-blood was not moving efficiently through the sma...
3-D snapshots of eyes reveal details of age-related blindness
... response to treatment.
Fujimoto's team uses an OCT machine with a resolution two times higher than commercial OCTs. In this study, they imaged the retinas
of 400 people suffering from different stages of macular degeneration. Their profiles range from a 54-year-old man with mild AMD and 20/20 vision, to ...
Ophthalmology highlights Jan. 2009
...severity of DME than the other factors. VEGF is a strong vascular permeability factor that is overproduced in response to reduced oxygen levels in the retinas
of people with retinopathy, and Dr. Funatsu's research suggests that VEFG is the key to the inflammatory response in DME. Building on earlier, similar...
Sunlight exposure plus low antioxidant levels may place older adults at risk for eye disease
... who were part of the European Eye Study. Participants also were interviewed about their lifetime sunlight exposure and had photographs taken of their retinas
to detect AMD.
Of the 4,400 participants with complete information available, 2,117 did not have AMD, 101 had neovascular (advanced, involving the ...
Painkiller May Prevent Diabetes-Related Retinal Damage
...gist and co-director of the Vision Discovery Institute at MCG's School of Medicine, said in a college news release.
For the study, she compared the retinas
of diabetic mice treated with pentazocine and those that didn't receive the drug and found dramatic differences. The findings suggest that the drug an...
September Ophthalmology research highlights
... lost visual acuity by the end of the study than the better LLD group. Contrast sensitivity and reading speed were also measured for participants; the retinas
were photographed; the eyes were examined for AMD progression; and the total area of GA in each eye was determined. Another predictor of visual acuity...
JCI table of contents: May 22, 2008
...oth of which affect the cell compartments known as mitochondria. As the same apoptotic cell deathinducing pathways were shown to be activated in human retinas
after retinal detachment, the authors suggest that although the HIV protease inhibitors cannot reattach the retina, they might be of clinical benefit ...
Dr. Michael Brownlee receives JDRF Rumbough Award for Scientific Excellence
...nt thiamine (vitamin B1), found that it blocked all major pathways of hyperglycemic damage, and that it blocked formation of structural lesions in the retinas
of long-term diabetic animals. His current studies include clinical trials of benfotiamine.
Dr. Brownlee also is the Director of the JDR...
Retinas in Medical Technology
Retinas in Biological News
When every photon counts
... of the photoreceptors. "And here nocturnal animals face a dilemma. They need lots of rods to detect the little available light - but that makes their retinas
thicker, so that more light is lost by scatter and diffusion before it reaches the photoreceptor outer segments", explains Leo Peichl at the Max Planc...
ORNL, St. Jude track neurons to predict and prevent disease
... cancer and Alzheimer's and Parkinson's disease.
St. Jude scientists have linked movement and changes of nerve cells, or neurons, in the brains and retinas
of young mice to certain diseases. Now, for the first time, they can use ORNL-developed software to analyze these vast amounts of data in record time....
Evolution and climate change research advances at Rutgers-Camden
... - is how Saidel conducts his own research at RutgersCamden. His interest in the exotic African butterfly fish is precisely because it has evolved two retinas
in each eye, but only feeds from information derived from one. The fish's highly specialized adaptations, from retina to brain, serve as a model for d...
Mammals can be stimulated to regrow damaged inner retina nerve cells
...retinal cell called the Mller glia.
"This type of cell exists in all the retinas
of all vertebrates," Reh said, "so the cellular source for regeneration is ...emarkable ability of cold-blooded vertebrates like fish to regenerate their retinas
after damage. Birds, which are warm-blooded, have some limited ability to r...
Gene therapy restores vision to mice with retinal degeneration
...rhythms but not with vision. The MGH team used the standard viral vector adeno-associated virus to deliver the gene encoding melanopsin throughout the retinas
of mice whose rod and cone photoreceptors had degenerated from lack of a crucial protein.
Four weeks after delivery of the gene, melanopsin normal...
Duke team explains a longtime visual puzzler in new way
...The Duke scientists asked how it is that humans routinely make correct behavioral choices in the world "when we can't know from the information on our retinas
what is actually out there," Purves said.
"The solution lies in humans accumulating, over millions of years of trial-and-error, the information ...
August LabBits: A media tip sheet from the MBL in Woods Hole
...s Peer Into Human Disease
Paradoxically, the photoreceptor cells in our retinas
release more of their neurotransmitter, glutamate, in the dark, when there ...tent cytotoxin that, in large doses, can kill nearby cells. What keeps our retinas
from disintegrating each night as glutamate continues to be released is unk...
A model photochemical compass for bird navigation
...and direction of a weak magnetic field.
The photoreceptor theory is supported by the fact that blue light photoreceptors have been detected in retinas
of migratory birds when they perform magnetic orientation. However, it has not been confirmed in the field or the lab that a magnetic field as weak as...
St. Jude defines eye cancer gene's role in retinal development
...l and N-myc-deficient retinas. The investigators then concluded the smaller retinas
likely resulted from an N-myc-related proliferation defect in the progenito... cues that coordinate the growth of the eye and retina.
Importantly, for retinas
to maintain nearly constant thickness across species that have different si...
Colorful view for first land animals
...iomedical Sciences, University of Queensland, Brisbane, Australia, analysed retinas
from Australian lungfish (Neoceratodus forsteri), thought to be the closest... and amphibian retinas. The DNA of five visual pigment (opsin) genes in the retinas
of lungfish reveals that these have more in common with four-legged vertebr...
Retinas in Biological Technology
Stretchable silicon camera next step to artificial retina
...ronics, configured in a stretchable, interconnected mesh.
The work opens new possibilities for advanced camera design. It also foreshadows artificial retinas
for bionic eyes similar in concept to those in the movie "Terminator" and other popular science fiction.
"Conformally wrapping surfaces with stretcha...
Retinas in Biological Definition
...e theory might propose that the light from the screen forms an image on the retinas
in the eyes and something in the brain looks at these as if they are the sc...etinas. A more sophisticated argument might propose that the images on the retinas
are transferred to the visual cortex where it is scanned. Again this cannot...
Retinas in Biological Dictionary
... of the eye create an image of the visual world on the retina , which serves much the same function as the film in a camera.... retina n. , pl. retinas
or retinae ( ). A delicate, multilayered, light-sensitive membrane lining the inner eyeball and connected by the optic nerve Fig. 1. Retina as...