NIH renews network focused on how genes influence drug responses
Findings will pave the way for individually tailored therapiesContinuing its strong support for studies on how genes affect responses to medications, the National Institutes of Health anticipates spending more than $150 million over five years to renew its Pharmacogenetics Research Network (PGRN). The research of this nationwide network of scientists will eventually help doctors tailor drug presc...Treatments have same target, different responses for lung cancer patients with genetic mutation
The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux), according to a new study published in the August 17 issue of the Some patients with non�small-ce...H5N1 avian flu virus vaccine induces immune responses in healthy adults
Results from a clinical trial demonstrate that high doses of an experimental H5N1 avian influenza vaccine can induce immune responses in healthy adults. Approximately half of those volunteers who received an initial and a booster dose of the highest dosage of the vaccine tested in the trial developed levels of infection-fighting antibodies that current tests predict would neutralize the v...Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial
Vical Incorporated announced today that an Ebola vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated, and produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 doses of vaccine. The Phase 1, randomized, placebo-controlled, dose-escalation study, the first human trial for any Ebol...Boosting newborns' immune responses
Newborn babies have immature immune systems, making them highly vulnerable to severe infections and unable to mount an effective immune response to most vaccines, thereby frustrating efforts to protect them. Researchers at Children's Hospital Boston now believe they have found a way to enhance the immune system at birth and boost newborns' vaccine responses. In a study published in the on...Reflecting On Personal Values Can Lower Stress Responses
Recent research findings suggest that reflecting on personal values can keep neuroendocrine and psychological responses to stress at low levels. Stress is implicated in the development //and progression of a broad array of mental and physical health disorders. Theory and research on the self suggest that self-affirming activities may buffer these adverse effects. A recent stu...Placing a Finger on Responses to Placebo Types
The placebo effect has been a raging topic for several years, gaining momentum over the past one year with lab trials being conducted to // analyze physiological responses to them. A new study, published in the Feb1 issue of the British Medical Journal examines the perceptible effect of types of placebo devices Vs pills on patients administered over a period of time. Earlier studies u...Adult stem cells are sensitive to responses from the environment
Researchers at the University of Pennsylvania have disclosed that a specific variety of adult stem cell is capable of changing into bone, muscle, neurons or other// types of tissue depending on the response from the physical environment. The researchers found that mesenchymal stem cells, which are commonly found in the bone marrow, are soliciting tangible clues from their local en...International Study Finds Ways to Maximize Effective Responses After Terrorism Incidents
A multi-disciplinary panel of blast-related injury experts from eight countries that have recently experienced terrorist attacks examined// and discussed their emergency medical response to blast events and identified common issues that could be used by others to enhance preparedness. The represented countries included: Colombia, Indonesia, Iraq, Israel, United Kingdom, United States, Sp...Brain Tumor Patients Survival Depends on Predicting Treatment Responses Earlier
WASHINGTON, D.C. A first-of-its-kind study presented at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals , declares that use of metabolic or molecular imaging to measure brain tumor patients' response to treatment is a powerful predictor of survival. "Our study opens the door to the possibility that brain tumor pati...Lymphocyte Cytokine Responses to Antigens and/or Mitogens
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...