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Response in Medical News

Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia

FRAZER, Pa., Aug. 3 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH ) today announced that the Journal of Clinical Oncology has published data from a pivotal phase 3 study demonstrating that TREANDA(R) (bendamustine HCl) for Injection improved clinical outcomes when compared to chl...

Savient Pharmaceuticals Receives Complete Response Letter from U.S. Food and Drug Administration for KRYSTEXXA(TM)

EAST BRUNSWICK, N.J., Aug. 2 /PRNewswire-FirstCall/ -- Savient Pharmaceuticals, Inc. (Nasdaq: SVNT ) today announced that the Company has received a complete response letter from the U.S. Food and Drug Administration (FDA) stating that the FDA can not at this time approve the Comp...

Addario Lung Cancer Medical Institute Announces Diagnostic Screening and Clinical Research Collaborations With Response Genetics, Inc.

SAN FRANCISCO, July 31 /PRNewswire-USNewswire/ -- The Addario Lung Cancer Medical Institute (ALCMI) today announced the execution of a letter of intent (LOI) to collaborate with Response Genetics, Inc. (Nasdaq: RGDX ) on molecular diagnostic testing and banking of advanced-stage Lung...

Statement by Jim O'Hara, Director, Produce Safety Project, in Response to the FDA's Announcement Regarding Guidance on Produce Safety

WASHINGTON, July 31 /PRNewswire-USNewswire/ -- The following is a statement by Jim O'Hara, Director, Produce Safety Project: We commend the FDA for moving forward on initiatives to improve the safety of fresh produce. The proposed guidance documents put out for com...

Mathematical modeling predicts response to Herceptin

PHILADELPHIA Cancer researchers are turning to mathematical models to help answer important clinical questions, and a new paper in Cancer Research , a journal of the American Association for Cancer Research, illustrates how the technique may answer questions about Herceptin resistance. Sofia...

Cell division find prompts overhaul of immune response modeling

Research at the Walter and Eliza Hall Institute into the mechanics of how two types of white blood cells grow and die is fundamentally changing the development of computer models that are used to predict how immune system cells respond to a pathogenic threat. A team led by Professor Phil Hodgkin...

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Response in Medical Technology

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

PHILADELPHIA, July 28 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, NASDAQ: SHPGY ), the global specialty biopharmaceutical company, announces that it has received a Complete Response letter today for INTUNIV(TM) (guanfacine) Extended Release from the Food and Drug Administration (FDA). Thi...

Acura and King Receive FDA Complete Response Letter Regarding Acurox(R)

PALATINE, Ill. and BRISTOL, Tenn., July 2 /PRNewswire-FirstCall/ -- Acura Pharmaceuticals, Inc. (Nasdaq: ACUR ) and King Pharmaceuticals, Inc. (NYSE: KG ) announced today that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter regarding the New Drug Application (...

Takeda Receives FDA Complete Response Letter for Alogliptin, an Investigational Treatment for Type 2 Diabetes

DEERFIELD, Ill., June 26, and OSAKA, Japan, June 27, 2009 /PRNewswire/ -- Takeda Pharmaceutical Company Limited ("Takeda") today announced that Takeda Global Research & Development Center, Inc., a wholly owned United States (U.S.) subsidiary received on June 26 (U.S. time) a complete response ...

MJFF's Rapid Response Innovation Awards Hit Mid-2009 With Over $1 Million Funded in High-Risk/High-Reward Approaches to Parkinson's Disease

NEW YORK, June 25 /PRNewswire-USNewswire/ -- As of mid-2009, The Michael J. Fox Foundation for Parkinson's Research has already funded over $1 million in high-risk, high-reward approaches to Parkinson's therapeutic development through its groundbreaking Rapid Response Innovation Awards . Projects...

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

SEATTLE, June 22 /PRNewswire-FirstCall/ -- Updated follow-up phase III EXTEND (PIX 301) clinical trial data enhances previously reported superior response rates for pixantrone over comparator including in high risk patient subgroups Additional Clinical Studies Also Highlighted at Pan ...

Micromet Presents Update on Blinatumomab's Response Rate and Duration in a Phase 1 Study in Non-Hodgkin's Lymphoma Patients

Data Presented at Meeting of European Hematology Association Confirms High Response Rate and Durability of Remissions BERLIN, June 8 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI ), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, in...

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Response in Medical Products

Lymphocyte IL-12 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-10 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-6 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-2 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-4 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IFN g Response to Tuberculosis, Quantitative

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

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Response in Medical Definition

Artificial induction of immunity

...as toxoids for immunization tends to produce a low response by the immune system, and thus poor immune memory...re contemporary approach for "boosting" the immune response of simpler immunogenic molecules (known as antige...es an immune response, thus amplifying the overall response and causing a more robust immune memory to the ant...

Body shaping

... adult and child health, often for life . [1] [2] Childhood obesity is on the rise in Europe as well. [3] Bariatric surgery In response to a serious obesity crisis, medical science has devised a handful of bariatric (obesity treatment) surgeries, including gastric bypass , stomach ...

Cachexia

...me autoimmune disorders . Cachexia physically weakens patients to a state of immobility stemming from loss of appetite, asthenia , and anemia , and response to standard treatment is usually poor. Contents 1 Disease settings 2 Mechanism 3 See also 4 External links...

Pathology

...r chemicals. Hyperplasia is a long-term adaptive response of cell division and multiplication , which can i... an increase in the size of cells in a tissue in response to stress, an example being hypertrophy of muscle cells in the heart in response to increased resistance to blood flow as a result ...

Medicine

... such as is taught in medical school , sees the core aspects of the process as the physician learning the patient's symptoms, concerns and values; in response the physician examines the patient, interprets the symptoms, and formulates a diagnosis to explain the symptoms and their cause to the patient and to ...

Personalized medicine

... 1 Limitations of traditional medicine 2 response of stakeholders to personalized medicine 2.... making the market more cost sensitive. response of stakeholders to personalized medicine There ...are treatment when a disease is established. The response of payers will be influenced by the nature of the ...
Response in Medical Dictionary

Immune response

Some help direct and regulate immune responses by binding to specific receptors ... Immune Response : How the Body Fights Back ... The immune response is how your body recognizes and defends itself against ... from birth) immunity -- form the first line of defense in the immune ...

Viral arthritis

... In viral arthritis , the immune system's response to the virus causes inflammation in the joints...... In viral arthritis , the immune system's. response to the virus causes inflammation in ... Mo... ... In viral arthritis , the immune system's response to the virus causes ... viral arthritis ? ......

Violence

...ho have only seen ... Building policy to prevent violence : an international collaboration ... Sexual violence : strengthening the health sector response - Prevention of child maltreatment ... The strong association between exposure to violence and the use of violence by young adolescents illu...

Vesicle

... rapid rates. ... Synaptic vesicle components are initially trafficked to the synapse using ... The mechanism of GLUT4 vesicle exocytosis in response to insulin is not understood. ... Vesicle binding to microtubules was not mediated through direct binding ... The Alzheimer Research Forum, a ...

Vasoconstriction

... User-generated article about fever, also known as pyrexia, a febrile response for unnatural changes ... Prevention of heat loss, such as vasoconstricti...d by ... associated with renal vasoconstriction favour the vasodilatory response ... Vasoconstriction , narrowing of blood vessels. It is mediated by...

Tuberculin

...ive (PPD) is ... The tuberculosis skin test (also known as the tuberculin or PPD test) determines whether a person has developed an immune response to the bacterium that causes ... Tuberculin Skin Tests, St. Joseph Mercy, Ann Arbor Michigan: A tuberculin skin test is done to see if you h...
Response in Biological News

Early detection and quick response are key to defense against anthrax attack

NEW YORK (July 24, 2009) -- A large attack on a major metropolitan area with airborne anthrax could affect more than a million people, necessitating their treatment with powerful antibiotics. A new study finds that in order for a response to be effective, quick detection and treatment are essentia...

Strong immune response to new siRNA drugs in development may cause toxic side effects

New Rochelle, NY, May 20, 2009Small synthetic fragments of genetic material called small interfering RNA (siRNA) can block production of abnormal proteins; however, these exciting new drug candidates can also induce a strong immune response, causing toxic side effects. Understanding how siRNA stim...

Tumor growth and chemo response may be predicted by mathematical model

The aggressiveness of tumors and their susceptibility to chemotherapy may become easier to predict based on a mathematical model developed at The University of Texas Health Science Center at Houston. In spite of extensive experimental and clinical studies, the process of cancer growth is not we...

HudsonAlpha investigator develops rapid response swine flu test

Huntsville, Ala. Dr. Jian Han, faculty investigator at the HudsonAlpha Institute for Biotechnology, has completed development of a rapid response, molecular-level assay for swine flu, the current strain of the H1N1 family of the influenza virus. The test, which can confirm swine flu in less than ...

Microparticle immune response modifier shows broad effects against recurrent or metastatic cancer

DENVER, CO and AUCKLAND, NZ (April 21, 2009) MIS416, a novel microparticle-based immune response modifier, demonstrated the ability to significantly reduce the number and size of metastatic tumors in preclinical mouse models of lung and breast cancers, Innate Therapeutics (formerly Virionyx Corpo...

Early isolation linked to enhanced response to cocaine

NEW ORLEANSDrug addiction affects millions of people around the world, causing numerous problems ranging from emotional and psychological difficulties to physical and health issues. Initial drug use can be motivated by curiosity or peer pressure, but in some animals, such as rats, it can also be t...

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Response in Biological Technology

Advanced Life Sciences Receives Complete Response Letter From FDA for Restanza(TM) (Cethromycin) in Community Acquired Pneumonia

CHICAGO, July 31 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS) announced that it received a complete response letter today from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for Restanza(TM) (cethrom...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

QUEBEC CITY, July 30 /PRNewswire-FirstCall/ - Medicago Inc. (TSX-V: MDG) a biotechnology company focused on developing highly effective and affordable vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced that it has achieved additional positive ...

Covance to Sell Its Interactive Voice and Web Response Services and Enter Into a Multi-Year Marketing Agreement with Phase Forward

PRINCETON, N.J., July 15 /PRNewswire-FirstCall/ -- Covance Inc. (NYSE: CVD ) today announced it has signed an agreement to sell its Interactive Voice & Web Response Services (IVRS/IWRS) business to Phase Forward (Nasdaq: PFWD ). In addition, Covance and Phase Forward have agree...

avVaa World Health Care Products, Inc. Announces Engagement of Koeppel Direct for their DRTV-Direct Response Television Media Buying Campaign

LUMBY, BC, July 2 /PRNewswire-FirstCall/ - avVaa World Health Care Products Inc. (Pink Sheets: AVVH), a global biotechnology company, manufacturer and distributor of nationally branded therapeutic, natural skin and health care products, announced the engagement of Koeppel Direct to manage their di...

ViroPharma Receives Complete Response Letter for Cinryze(TM) Supplemental Biologics License Application for Acute Treatment of Hereditary Angioedema

- Company Also Granted Expansion of Prophylaxis Therapy Label to Include Patient Labeling for Self-Administration - EXTON, Pa., June 4 /PRNewswire-FirstCall/ -- ViroPharma Incorporated (Nasdaq: VPHM ) today announced that it has received a Complete Response letter from the U.S. Food and Dr...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

First Randomized Trial to Demonstrate Superior Clinical Benefit in Relapsed/Refractory Aggressive NHL ORLANDO, Fla., June 1 /PRNewswire-FirstCall/ -- Intent to treat Analysis results per FDA agreed upon Statistical Analysis Plan Significant Increase in Complete Rem...
Response in Biological Products

Signal software from Cambridge Electronic Design Limited

Description:... Sweep- based acquision and analysis software for electrophysiology and evoked response type applications. Contains powerful stimulus generation capabilities and many flexible analysis functions including automated waveform feature detect...
Company:Cambridge Electronic Design Limited

CellSensor CRE-bla HEK 293T Cell Line from Invitrogen

Description:... The CellSensor CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE). To obtain the cell line the CRE-bla construct was transduced into HEK 293T cells by lentivirus. Subsequent flow cytometry was used to i...
Company:Invitrogen

Mouse Anti-Porcine Pyruvate Dehydrogenase (PDH), complex Immunocapture Kit Monoclonal Antibody, Protein G-Agarose Conjugated, Clone 15D3G9C11 from MitoScience LLC

Description:...t limited to examining alterations in assembly of the complex in genetic PDH deficiency altered PDH functioning in late-onset diabetes (NIDMM) and the response of the enzyme complex to diet, exercise and sepsis....
Company:MitoScience LLC

In Situ Pan-Caspase Assay Kit from CHEMICON

Description:...mponent of this process is a cascade of proteolytic enzymes called caspases. These enzymes participate in a series of reactions that are triggered in response to pro-apoptotic signals and result in the cleavage of protein substrates, causing the disassembly of the cell. Caspases have been identified in org...
Company:CHEMICON

In Situ Pan-Caspase Assay Kit, Sulforhodamine from CHEMICON

Description:...mponent of this process is a cascade of proteolytic enzymes called caspases. These enzymes participate in a series of reactions that are triggered in response to pro-apoptotic signals and result in the cleavage of protein substrates, causing the disassembly of the cell. Caspases have been identified in org...
Company:CHEMICON

VersArray ChipReader 3 m System from Bio-Rad

Description:...er confocal systems designed for rapid imaging of microarrays. These are advanced scanners that meet your expectations, differentiating between a spot response and background level, and optimizing the signal on the bottom as well as the top end of the range for increased sensitivity. Results with VersArray Ch...
Company:Bio-Rad
Response in Biological Definition

Allostery

... In biochemistry , an enzyme or other protein is allosteric if its activity or efficiency changes in response to the binding of an effector molecule at a so-called allosteric site . Changes that enhance activity are referred to as allosteric activation ,...

Allostery

... In biochemistry , an enzyme or other protein is allosteric if its activity or efficiency changes in response to the binding of an effector molecule at a so-called allosteric site . Changes that enhance activity are referred to as allosteric activation ,...

Antibody

... IgM 3.4 IgD 3.5 IgE 4 Function 4.1 The humoral immune response 5 Medical applications 6 Biochemical applications 7 See a...nly certain immune mechanisms respond to antigens. The humoral immune response When a macrophage ingests a pathogen , it attaches parts of its prote...

Antigen

... kinds of antigens: Immunogen - Any substance that provokes an immune response (provokes immunity) when introduced into the body. An immunogen is always a...macromolecule (protein, polysaccharide). Its ability to provoke the immune response depends on its foreignness to the host, molecular size, chemical compositio...

Apoptosis

...optosis 1.1 Cell damage or infection 1.2 response to stress or DNA damage 1.3 Homeostasis 1.4 ...ult in the development of cervical cancer . response to stress or DNA damage Stress conditions (such...n orderly manner without eliciting an inflammatory response [5] , [6] . In studies on mouse embryos lacki...

Arabidopsis

...d, far red and infrared light. While gravitropic response of Arabidopsis root organs is the predominant tr...tropic action have shown both negative phototropic response to blue or white light, and positive phototropic response to red light. The photosensitive pigments phytochr...
Response in Biological Dictionary

Immune response

An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells. It detects a wide variety of agents, from viruses to parasitic... Immune response - Overview, The immune response is how yo...

Voluntary muscle

...btain higher ... Much of muscle contraction ... Voluntary muscle contraction is used to move the body and can be finely ... move muscles in response to voluntary and ... ...

Uropod

...otor system were investigated in ... It is also suggested that the uropod response to body rolling during walking is ... II. Modulation Of uropod motoneu...roprioception. M ... The uropod motoneurones showed little or no synaptic response when the treadmill ... Product Condition: The Uropod Dry Bag - 37L is ...

Tropism

...ment of a biological organism, usually a plant, in response to an environmental stimulus. In tropisms, this response is dependent on the direction of the stimulus . Vi... at Encyclopedia.com. ... tropism , involuntary response of an organism, or part of an organism, involving ...

Transferrin receptor

...n . It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increa.... Mechanism of Transferrin Receptor Down-regulation in K562 Cells in response to ... in stimulated K562 cells, while transferrin receptor synthesis i...

Thymus gland

...derneath the top of the breast ... This is because the thymus gland , in response to acute stress such as an ... Get information, facts, and pictures abou...ng and maturation of special ... allergies are classified as an immune response in western medicine. ... Thymus gland phlegm stagnation is a primary c...
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