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Resequencing in Medical News

GeneGo Awarded NIH Grant to Develop Pharmacogenomics Software Suite

...iological consequences of sequence variations on disease susceptibility and drug response. "Genome-wide association studies and next-generation resequencing projects are already generating vast amounts of data on genetic factors contributing to disease susceptibility and variability in the pharmacological ...

Researchers identify the gene responsible for a rare form of congenital anemia

... succeeded in delimiting a genomic region likely to contain the gene responsible for congenital sideroblastic anemia in these families. The direct resequencing of this gene made it possible to identify a causal mutation in a gene to which no physiological role could have been attributed. Subsequently, in coll...

15 human genomes each week

...ent of the next-generation sequencing technologies allows us now to search for all the types of somatic change in cancer genomes and to begin complete resequencing of whole cancer genomes, acquiring full catalogues of somatic changes, ultimately in thousands of cancers as a leading player in the International Can...

High -tech Mitochondrial DNA Sequencing Tool Updated

...p v1.0. In addition to nitty-gritty technical innovations that vastly improved the rate and speed of the chip, the v1.0 marked the first mitochondrial resequencing microarray designed as a potential screening tool for cancer. "With mitochondrial DNA, there is a mass advantage," said Dr. Anirban Maitra, an author ...

MitoChip v2.0 – the new Mitochondrial DNA sequencing too

...p v1.0. In addition to nitty-gritty technical innovations that vastly improved the rate and speed of the chip, the v1.0 marked the first mitochondrial resequencing microarray designed as a potential screening tool for cancer. "With mitochondrial DNA, there is a mass advantage," said Dr. Anirban Maitra, an author ...
Resequencing in Medical Technology

Microarray Sequence Capture Speeds Large-Scale Resequencing of Targeted Genomic Regions

MADISON, Wis., Oct. 15 /PRNewswire/ -- Researchers at Baylor College of Medicine and Roche NimbleGen Inc., a fully integrated part of Roche Applied Science, today have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip(...

Lexicon Develops Antibodies That Lower Triglycerides and Cholesterol as Potential New Therapy for Heart Disease

...such forward-looking statements, whether as a result of new information, future events or otherwise. (1)Stefano Romeo et al., "Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL," Nature Genetics, April 2007. Contact for Lexicon: ...
Resequencing in Biological News

Microarray sequence capture speeds large-scale resequencing of targeted genomic regions

Researchers at Baylor College of Medicine and Roche NimbleGen Inc., a fully integrated part of Roche Applied Science, today have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip microarrays in preparation for high-through...

TGen investigators devise faster, cheaper way of analyzing the human genome

...ate method such as custom SNP genotyping. Conducting polymorphism discovery and variant calling within one sequencing experiment. Exhaustively resequencing for all common and rare variants. The new method of analyzing human genetics should enable scientists at TGen and elsewhere to push ahead with key...

Rare genetic mutations protect against hypertension

... mutation by selectively inhibiting a single gene or several genes. In addition, the study more broadly underscores the value of genetic analysis -- resequencing of genes and genomes to ferret out functional mutations -- for understanding individual risk of disease. A major question about the genetic underpin...

Washington University increases fleet of Roche Genome Sequencer FLX Systems

... wide variety of projects with the 454 Sequencing technology, ranging from the sequencing of new complex genomes to the diverse microbial world to the resequencing of portions of the human genome to identify genetic variations that may be associated with human diseases. This will include using the instruments fo...

Mitochondrial DNA sequencing tool updated

... v1.0. In addition to nitty-gritty technical innovations that vastly improved the rate and speed of the chip, the v1.0 marked the first mitochondrial resequencing microarray designed as a potential screening tool for cancer. "With mitochondrial DNA, there is a mass advantage," said Dr. Anirban Maitra, an author...
Resequencing in Biological Technology

New method of selecting DNA for resequencing accelerates discovery of subtle DNA variations

A new technology developed by scientists at Emory University will allow researchers to more easily discover subtle and overlooked genetic variations that may have serious consequences for health and disease. Called Microarray-based Genomic Selection (MGS), the research protocol allows scientists t...

'Biology in Pico-Liter Droplets' is Focus of Presentation at LabAutomation 2009

...t proven assays for high-speed workflows with minimized process-induced bias or error. RainDance's initial application will focus on the targeted resequencing of the human genome -- one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution ...

RainDance Technologies and Harvard University to Share in First Massachusetts Life Sciences Center Cooperative Research Grants

...lets at a rate of 10 million per hour, in two key areas: One, the targeted resequencing of the human genome -- stirring significant interest and excitement in one ...or error. RainDance's initial application will focus on the targeted resequencing of the human genome -- one of the fastest-growing segments of the $1 billio...

J. Craig Venter Institute Names Robert Friedman, Ph.D., Deputy Director of West Coast Facility

.... In addition, she was responsible for implementing and managing a forensic resequencing pipeline at Celera. This pipeline was specifically set up to perform the mtDNA resequencing on the World Trade Center (WTC) victim and reference samples for the purpos...

febit Receives U.S. Patent for Microfluidic Extraction Method

...is of a novel technology that enables the expanded use of next-generation sequencers in genomic research. Further investigation of the human genome by resequencing will particularly benefit from the new method: febit uses its microfluidic biochip system for sequence-based selective isolation of nucleic acids from...

Venter Institute Scientists Create First Synthetic Bacterial Genome

...for Creating the Synthetic M. genitalium The process to synthesize and assemble the synthetic version of the M. genitalium chromosome began first by resequencing the native M. genitalium genome to ensure that the team was starting with an error free sequence. After obtaining this correct version of the native g...

SLIM Search, Inc. Sponsors Next Generation Sequencing Conference for the Biomedical Market

...ilable DNA- sequencing platforms that have resulted in a flurry of activity in the sequencing community. Offering quality programs ranging from Genome resequencing for Mutation Screening through the Next-Next Generation Sequencing Technologies this conference focuses on the next generation sequence analysis probl...

Wisconsin company with SARS diagnostic role lands $13 million investment

...03, according to Joleen Rau, director of marketing, the firm worked with the Genome Institute of Singapore during the SARS epidemic. The companys SARS resequencing array helped to speed up contact tracing of infected individuals, Rau said. Traditionally, contact tracing is used to determine the genetic origins...

SeeSNP Propietary Analysis Advantages

...eased or drug-responsive populations. Typical studies involve the resequencing of 20500 amplicons in 50 or more patients, generating ...s article, we will discuss the common problems encountered in SNP resequencing and the innovative solutions developed at Agencourt. ...

SEESNP DISCOVERY

...ntification of SNP loci. Our SeeSNP service is based on a targeted resequencing strategy and is fueled by our capacity to sequence over 20 million... than 90%. SNP IDENTIFICATION resequencing of either a Coriell discovery panel or customer-provided samples...
Resequencing in Biological Products

SeeSNP Discovery / Resequencing from Agencourt Bioscience

Description: Agencourt offers SNP loci identification through targeting resequencing. This service includes automated assay design, intensive assay validation/optimization, high throughput PCR setup and sequencing of Corriell or customer-supplied samples and sequence alignment and analysis. Agencourts SNP Dis...
Company:Agencourt Bioscience
Resequencing in Biological Dictionary

Genomic DNA

...through the process of molecular cloning. There are different types of DNA libraries, including cDNA libraries and genomic libraries . DNA ... resequencing a large region of genomic DNA , usually of >100 kilobases (kb), from ... Genomic DNA , pooled isolates from individual patients or tissue s...
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