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Reproducibility in Medical News

Studies Investigate Diagnostic Performance and Reproducibility of Pathwork Diagnostics' Tissue of Origin Test

SUNNYVALE, Calif., Nov. 8 /PRNewswire/ -- Pathwork Diagnostics, a genomics-based diagnostics company focused on oncology, announced that its Pathwork(TM) Tissue of Origin Test is the focus of two studies featured in poster presentations at this week's 12th Annual Meeting of the Association for...

NuVasive to Present at the BMO Capital Markets 9th Annual Focus on Healthcare Conference

... combines four categories of products that collectively minimize soft tissue disruption during spine surgery with maximum visualization and safe, easy reproducibility for the surgeon: NeuroVision(R), a proprietary software-driven nerve avoidance system; MaXcess(R), a unique split-blade retractor system; a wide varie...

NuVasive Reports Second Quarter 2009 Financial Results

... combines four categories of products that collectively minimize soft tissue disruption during spine surgery with maximum visualization and safe, easy reproducibility for the surgeon: NeuroVision(R), a proprietary software-driven nerve avoidance system; MaXcess(R), a unique split-blade retractor system; a wide varie...

Growing Proteomics Market and the Current Economic Crisis Could Act in Tandem to Spur Growth in the European 2 Dimensional Gel Electrophoresis Market, States Frost & Sullivan

...ring needs of customers. "Sample preparation is a major challenge that the industry needs to overcome," states Ramachandran. "It affects both the reproducibility and the resolution of the 2DE experiment which, in turn, influences the end results." It is advisable for market participants to focus on determi...

Boston Scientific's Urology/Gynecology Products Featured in Studies at International Urogynecological Association Annual Meeting

...gament Fixation Associated with Paravaginal Repair Using the Pinnacle Device: An Anatomical Study - Renaud de Tayrac, M.D. This study evaluates the reproducibility and anatomical risks after anterior sacrospinous ligament fixation associated with paravaginal repair using the Pinnacle Pelvic Floor Repair device. ...

First-Ever Standardized Scales to Measure the Skin's Aging Process Are Presented at THE Aesthetic Show

...diverse ages, skin types and ethnicities. As part of this process, the experts rated 35 to 50 real-life images of people, and evaluated the images for reproducibility of results. The Merz Scales were then generated as five-point scales using computer-morphed photography. Specific anatomical changes related to a...
Reproducibility in Medical Technology

Study of Pathwork Diagnostics' Tissue of Origin Test Published in the Journal of Molecular Diagnostics: Investigates Test Reproducibility in Multiple Labs to Determine Primary Tumor in Cancer Cases

SUNNYVALE, Calif., Dec. 14 /PRNewswire/ -- Pathwork Diagnostics, a genomics-based diagnostics company focused on oncology, announced that its Pathwork(R) Tissue of Origin Test is the focus of a study published in the January issue of The Journal of Molecular Diagnostics. Pathwork's genomics-ba...

Malaria Vaccine Developer, Sanaria Inc., Receives 2009 Vaccine Industry Excellence Award for Best Early-Stage Vaccine Biotech

...is composed of live, attenuated parasites. This unique formulation, having satisfied rigorous FDA scrutiny for safety, sterility, purity, potency, and reproducibility of manufacturing, is now undergoing clinical testing in volunteers for safety and efficacy. About Sanaria Inc. The company's primary mission ...

Phase 1 Trial of Whole-Parasite Malaria Vaccine to Begin

...nstead of small portions of the parasite. Having met the US Food and Drug Administration's (FDA) rigorous safety, sterility, purity, potency, and reproducibility requirements for testing in humans, Sanaria's vaccine candidate is to be assessed in healthy US volunteers at two sites in Maryland -- the US Naval Me...

Verification Studies of IntelligentMDx's Proprietary Molecular Diagnostic Assay Process Have Been Completed

... the IntelligentMDx BK Viral Quantitative Assay are complete. Under the verification protocol the Limit of Detection, linearity, specificity and reproducibility and robustness of the BK Viral Quantitative Assay were determined. The data obtain agreed with internally generated analytical performance data genera...

Rosetta Genomics Announces Commercial Availability of its First MicroRNA-Based Diagnostic Test; Will Host Teleconference to Discuss Launch of Future Tests

...on squamous non-small cell lung cancer lack standardization, are difficult to reproduce, and have low accuracy. Studies that reviewed the accuracy and reproducibility of histopathological classification of lung cancer found that 30%~40% of samples had been misclassified. Rosetta Genomics will host a conferen...

Rubicon Provides Genome Amplification for the Cancer Genome Atlas Project

...nt of commercial development for Rubicon. "IGC-BRC collaborators were able to show that pre-amplification of patient DNA can increase the sensitivity, reproducibility and robustness of analysis of patient samples using major analytical instruments." Rubicon provides custom GenomePlex services for major pharmaceuti...
Reproducibility in Medical Products

CD-Chex Plus BC Immunophenotyping Control

Description:...Chex Plus BC is an assayed control for immunophenotyping with Beckman Coulter® flow cytometry systems. CD-Chex Plus BC determines the accuracy and reproducibility of all the steps involved in the process of immunophenotyping, including red blood cell lysis. Reference values for five subsets of leukocytes include...
Company:Streck

CD-Chex Plus Immunophenotyping Control

Description:... CD-Chex Plus is an assayed control for monitoring immunophenotyping by flow cytometry. CD-Chex Plus determines the accuracy and reproducibility of all the steps involved in the process of immunophenotyping, including red blood cell lysis. Reference values for five subsets of leukocytes include...
Company:Streck

SITA SWAP Field Analyzer Software

Description:...umphrey Field Analyzer, SITA SWAP exhibits greater dynamic range and shows less inter-test variability than Full Threshold SWAP, at the same degree of reproducibility as Full Threshold SWAP. SWAP has been shown to correlate with the earlier glaucoma damage detected with RNFL imaging....
Company:Carl Zeiss Meditec, Inc.

Tag-It™ Cystic Fibrosis Kit

Description:...tations. The validated performance characteristics of the Tag-It™ Cystic Fibrosis Kit have been established in multisite studies demonstrating reproducibility by lot, site and operator....
Company:Tm Bioscience Corporation

erCRP

Description:...utomated clinical chemistry analyzers. The erCRP reagent satisfies AHA and CDC recommendations for a high sensitive method to ensure a reliability and reproducibility of results across the entire measurable range (0.15 320mg/L). The method provides excellent correlation against other commercially available assays a...
Company:ThermoFisher Scientific

Mini-PROTEAN 3 Dodeca Cell With Multi-Casting Chamber

Description:...multi-casting chamber, eliminating sources of variation and improving reproducibility. Alternatively, Ready Gel precast gels offer the convenience and reproducibility demanded by higher throughput labs....
Company:Bio-Rad Lab Equipment
Reproducibility in Biological News

Biomedical researchers create artificial human bone marrow in a test tube

...stromal cells and osteoblasts, another type of bone marrow cell. "The geometrical perfection of the polymer molded by spheres is very essential for reproducibility of the drug tests and evaluation of potential drug candidates," Kotov said. "The scaffold for this work had to be designed from scratch closely mimick...

Fox Chase researchers discover a method for clamping down on a cancer-promoting enzyme

...les for their ability to block phosphorylation by pure PAK1 protein. Any small molecules that blocked PAK1 were noted and were then ranked by potency, reproducibility and commercial availability. IPA-3 came out ahead of the others through this winnowing process, and the researchers then tested IPA-3 to demonstrate ...

Texel paleothermometer for climate reconstruction perfected

...tudied several aspects of this in greater detail and made significant improvements to the determination. With a new detection method the analytical reproducibility of the TEX86 paleothermometer was brought to 0.3C and the deviation in the results measured was reduced to 5% of the average. The TEX86 values for org...

NAS report offers new tools to assess health risks from chemicals

...ssessment states that the technological hurdles that could have limited the reproducibility of data from toxicogenomic technologies have been resolved and recommends w...nd were leaders in the development of many of the standards for quality and reproducibility that are used today. The report, which was prepared by a panel of 16 s...

Pacific Rim researchers to collaborate on distributed bioinformatics analysis of avian flu

...e an integrated computational environment to support easy access to a set of universal tools, novel algorithmic approaches and tracking mechanisms for reproducibility at a global level. Having Asian researchers involved in the TATRC-funded project lends an added dimension of urgency and depth to the U.S. resea...

Connect the Quantum Dots

...esearch proves this important fundamental principle and lay the necessary groundwork for researchers to further improve its sensitivity, stability and reproducibility for biomedical applications. "Our method has a long-term impact on biomedical diagnostic applications which currently rely on the fluorescence of ...
Reproducibility in Biological Technology

Improve Recovery and Reproducibility with Pre-Treatment of Analytical TSK-GEL G3000SWXL Size Exclusion Columns

T.J. Higley, Tosoh Bioscience LLC and Richard Cornell, Wyeth BioPharma Abstract: During a recent method optimization and investigation at Wyeth BioPharma, pre-treatment with bovine serum albumin improved reproducibility and recovery ...

Separation Reproducibility With the BioLogic Chromatography Systems

Kevin Thornton, PhD, Bio-Rad Laboratories, Inc., Hercules, CA 94547 USA Introduction In chromatographic separations, sample component elution times are often used both for identification and to program automated chromatography steps ...

Carbon Design Innovations, Inc. Introduces Carbon Nanotube Probe Technology for Atomic Force Microscopy, CNT-Probes Deliver New Level of AFM Imaging Performance

...ers with deep-trench scanning ability not currently available. As a result, C|D|I probes offer customers greater imaging flexibility, performance and reproducibility that will enable them to make significant advances in AFM research. The new CNT AFM probes from C|D|I are compatible with all major AFM systems, givi...

ZyGEM Corp. Signs Agreement to Incorporate Its Breakthrough DNA Extraction Technology Into Rubicon's Research and Diagnostic Products

... small clinical samples into large amounts of pure DNA with uniform concentration and molecular weight that increase the sensitivity, specificity, and reproducibility of analysis in research and diagnostic applications, including single cells, formalin-fixed tissue and plasma. Rubicon sells licenses and kits to the ...

Cell Biosciences Launches Next-Generation Protein Characterization System

...ed design of the CB1000 system provides significant improvements in assay performance and automation, including a doubling of sample throughput. Assay reproducibility and stability have been increased through the incorporation of precise temperature control systems. In addition, the CB1000's software package, Compas...

Spiral Biotech to Introduce New Autoplate Spiral Plating System at ASM General Meeting in May

...oratory that uses microbial concentration samples greater than 1,000 cfu/g or cfu/ml, or any application where counts are high and standardization and reproducibility are key. Spiral Biotech will unveil the new Autoplate at the ASM General Meeting, May 18-20, 2009, in Philadelphia. For more information, visit t...
Reproducibility in Biological Products

PhastGel DNA Silver Staining Kit from GE Healthcare, formerly Amersham Biosciences

Description:...homogeneous and gradient polyacrylamide gels.Separate proteins and peptides on denaturing, native, and isoelectric focusing gels.Save time and improve reproducibility with precast gels, buffer strips, and staining kits.Achieve detection sensitivity comparable to that of radioisotopes with ready-to-use silver stainin...
Company:GE Healthcare, formerly Amersham Biosciences

DeStreak Reagent from GE Healthcare, formerly Amersham Biosciences

Description:... DeStreak Reagent, 1 ml. Improves reproducibility and quality of 2-D gels by preventing streaking.Eliminates extra spots caused by nonspecific oxidation of proteins.Stabilizes proteins throughout enti...
Company:GE Healthcare, formerly Amersham Biosciences

ValveLink8.2 Lee Valve 1.5-4ms Perfusion System from AutoMate Scientific, Inc

Description:...re-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applications. >UL> Increase reproducibility with 1.5-4 millisecond accuracy Run experiments automatically - even unattended Microprocessor-based for accuracy and flexibility Turnkey perfusion...
Company:AutoMate Scientific, Inc

ValveLink8 Pinch Valve Perfusion System from AutoMate Scientific, Inc

Description:... or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applications. Increase reproducibility with 10 millisecond accuracy. Run experiments automatically - even unattended Microprocessor-based for accuracy and flexibility Turnkey perfusion ...
Company:AutoMate Scientific, Inc

ValveLink4 Economy Pinch Valve Perfusion System from AutoMate Scientific, Inc

Description:...re-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applications. >UL> Increase reproducibility with 10 millisecond accuracy Run experiments automatically - even unattended Microprocessor-based for accuracy and flexibility Turnkey perfusion sy...
Company:AutoMate Scientific, Inc

N5 Submicron Particle Size Analyzer - 230V from Beckman Coulter

Description:...one to inaccuracy, in addition to being cumbersome. Features: User-friendly Microsoft Windows-based software • Multi-angle analyses • High reproducibility • Small quantities of sample required • 21 CFR Part 11 compliance • 25 mW laser ...
Company:Beckman Coulter
Reproducibility in Biological Definition

Replication

...stics replication refers to repeated measurement of a phenomenon, so that the variability can be estimated. In science , this is a synonym for reproducibility . ...
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