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Repression in Medical News

Brown professor continues debate over recovered memory

...s prior to 1800, would have witnessed it and portrayed it in a nonfictional work or in a fictional character." They launched a contest, known as the " repression Challenge ," offering a $1,000 prize to anyone who could identify a pre-1800 literary example of traumatic memory that has been repressed by an otherw...

Vets Who Repress Traumatic Memories May Not Be Worse Off

... personality. The authors called for more research, while noting that their exclusive focus on male patients as well as their use of older PTSD and repression measures (which had been in effect during the initial CDC study) could limit the accuracy of their findings. The finding, they said, is important b...

Mach One Corporation Announces Hand Carried Product as a Potential Solution to Swine Flu (H1N1) Virus

...al prevention of viruses in the nasal pharyngeal region tract of humans will ultimately permit substantial reduction or elimination of the virus. This repression or blocking of virus will permit a significant decrease in shedding and passage of the virus from host to host. In addition, the resulting decrease in...

World Anti-Aging Congress 2009 Defies Global Economic Downturn, Demonstrating Strength of Anti-Aging Medical Movement

... has been exposed, the founder and Editor-in-Chief of the Archives, Prof. Dr. Imre Zs.-Nagy, MD, blows the whistle on fourteen years of censorship and repression of the science of anti-aging medicine, and advanced preventive medicine, by the gerontological establishment. Quoting Prof. Dr. Zs.-Nagy, who sta...

Enzyme and vitamin define the yin and yang of asthma

...he food chain," they said. In the future, they said, they hope to identify the relationship between the synthesis of vitamin A in the body and the repression of MMP7. ...

JCI online early table of contents: Jan. 12, 2009

...interaction depended on the protein casein kinase 1-delta (and not the protein TGF-beta receptor) and led to activation of a tumor-suppressor gene and repression of a tumor-promoting gene. At the cellular level, FHL1, FHL2, and FHL3 inhibited the growth of a human tumor cell line both in vitro and when transpla...

Scripps research team unravels new cellular repair mechanism

...1 phase, in preparation for the subsequent S phase. The team has now shown that when such stalls occur, collectively referred to as DNA stress, Nrm1's repression of the G1 genes is blocked, allowing those genes to be turned back on. This presumably enables production of proteins needed to correct the problem th...

How embryonic stem cells develop into tissue-specific cells demonstrated

...ling this process, resolving a long-standing question as to whether the stem cells achieve their development through selective activation or selective repression of genes. The collaborative research group, which included Dr. Eran Meshorer of the Department of Genetics at the Silberman Institute of Life Scie...

Is increased Slug expression associated with the progression to esophageal cancer?

...ar invasiveness and metastasis. The main mechanism by which cell-cell adhesion is repressed in oesophageal adenocarcinoma is thought to be through the repression of the cell adhesion molecule E-cadherin. This study reports that a potential mechanism by which E-cadherin could be silenced is through over expressi...

Unsuspected protein determines resistance to breast cancer treatment

...led the authors to propose that CDK10 normally represses the ETS2 transcription factor and that the loss of CDK10 expression results in relief of ETS2 repression and upregulation of c-RAF transcription. Enhanced c-RAF activation results in activation of mitogen-activated protein kinase and increased cyclin D1 e...
Repression in Medical Products

Dual Media Kit

Description:...itations of Luria Broth (LB) when used for protein expression. LB, while an excellent medium for normal E. coli manipulation, is not a good medium for repression of protein expression during cell expansion, nor is it ideal for protein expression when inducer is added....
Company:Zymo Research Corporation
Repression in Biological News

Protecting cells from their neighbors

...vity in the milieu. The silencing is governed by a repression mechanism previously described in earlier work -, ...s and molecular mechanisms that participate in the repression and activation of the genomes of distinct species ...to other organisms. Given that the transcriptional repression in germ cells is a general characteristic of all t...

Parasites ready to jump

...bind to specific RNA molecules that serve as precursors of the endo-siRNAs. Furthermore, the team pinpointed an entirely novel feature of this system: repression of transposon activity was also detectable when multiple copies of a mobile element were present in the cell but not yet incorporated into the genome....

Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals

...proximately 5 hours, and transit into the nucleus took 8 hours; OGFr remained in the nucleus for up to 8 days. Transport through the nuclear pore and repression of cell proliferation required two of the three nuclear localization signals (NLS) in OGFr. These results show that the pathway for regulating the ce...

Ex vivo neural stem cell expansion

... progenitor cells increases stem cell self-renewal both in vitro and in vivo. They furthermore show that Bmi-1-mediated self-renewal is dependent upon repression of p21 by the forebrain-specific transcription factor, Foxg1. ...

New molecular insight into vertebrate brain development

...l overproliferation and the formation of an expanded neural progenitor cell population. Decreased YAP/TEAD activity led to increased cell death, while repression of YAP/TEAD target genes induced premature neuronal differentiation. Owing to the evolutionary conservation of the Hippo signaling pathway, Dr. Ga...

CSHL team traces extensive networks regulating alternative RNA splicing

...d where the splicing factors Fox-1 and Fox-2 attach, or bind, to unedited target RNA transcripts. "The effect of splicing factors on the activation or repression of splicing often depends on the location and context of the RNA sequences they bind," Dr. Krainer explained. It was known that the two proteins ...

Gene is likely cause of stroke-inducing vascular malformations

...tor of the Laboratory for Accelerated Vascular Research and Mildred V. Strouss Endowed Chair in Vascular Surgery at UCSF. "Furthermore, we found that repression of the gene in already-ill mice led to their recovery." Approximately one million people worldwide suffer from BAVMs, though very little is known ...

Controlling embryonic fate by association

...and his colleagues found that two critical embryonic cell proteins Nanog and Oct4 associate with specific components that are parts of transcription repression complexes. These complexes affect the way that genes are expressed and carry out their tasks in the cell. A special complex called NODE (Nanog and...

Researchers discover critical detail of cellular defense against genetic mistakes

... the studys key finding, experiments revealed that repression of protein synthesis during NMD is controlled the ...e importance of eIF3 as a target for translational repression during NMD using an experiment with an mRNA sequen...and thus that eIF3 is a must for the translational repression that makes NMD possible. In Maquats model of ...

Making sense of antisense microRNAs

...NA precursor mir-iab-8, which is processed into active regulatory RNAs. When ectopically expressed, mir-iab-8 generates homeotic phenotypes via direct repression of Hox gene targets. The paper from Dr. Welcome Bender (Harvard Medical School) demonstrates that knock out of miR-iab-4 reveals the existence of a mi...
Repression in Biological Technology

Mach One Corporation Developing a Nasal, Hand Carried Product as Solution to Swine Flu (H1N1) Virus

...al prevention of viruses in the nasal pharyngeal region tract of humans will ultimately permit substantial reduction or elimination of the virus. This repression or blocking of virus will permit a significant decrease in shedding and passage of the virus from host to host. In addition, the resulting decrease in...

DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors

...n shown to express better than comparable pET vectors. pJexpress vectors carry a copy of the lacI gene and symmetrical lac operators to ensure optimal repression prior to induction. These vectors are available with either the T7 or T5 promoter. DNA2.0's research has shown that the T5 promoter routinely expresse...

Islands in the Clickstream: A Vision of Possibilities

..., for example, are a good gill net in which such people can be collected, observed, or manipulated. That's much more effective for social control than repression of such tendencies and their social expressions. We may find it desirable to build larger percentages of people amenable to such manipulation. That...

FlexiPlate siRNA

...cial neural network. Nat. Biotechnol. 23 , 995. 2. Farh, K.K. et al. (2005) The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science 310 , 1817. 3. Judge, A.D., Sood, V., Shaw, J.R., Fang, D., McClintock, K., and MacLachlan, I. (2005) Se...

RNA Interference and Gene Silencing: History and Overview

... regulates C. elegans developmental timing through translational repression of target transcripts. Research indicates that the C. elegans l...d inactivates the translation initiation factor, eIF2a, leading to repression of translation. (39 ) In the other pathway,...

Recommendations for Successful siRNA Library Screens

...a transfection of siRNAs inhibited etoposide-activated apoptosis (monitored by caspase 3 activity, see Figure 3). By definition, repression of Confirmed Positive genes resulted in low caspase 3 activity in assays from at least two gene-specific siRNAs. To examine the accuracy ...

Getting Started with MicroRNA Research

... protein translation by binding to sequences in the 3' untranslated region of specific mRNAs. The exact mechanism of translation repression is still undefined. *=mature miRNA sequence The Research Questions What miRNAs Exist? Over the past s...

pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins

...ion of the induction profile to be expected in double-stable lines made by selecting stably integrated inducible vectors. This is due to the tight repression that occurs for chromosomally integrated ecdysone-responsive promoters, compared with the relatively high background normally seen in transient tr...
Repression in Biological Products

Rabbit Anti-HDAC4 Polyclonal Antibody, Unconjugated from GeneTex

Description:... of HDAC 4 protein in the cytoplasm. In the nucleus, HDAC4 associates with the myocyte enhancer factor MEF2A. Binding of HDAC4 to MEF2A results in the repression of MEF2A transcriptional activation. HDAC4 has also been shown to interact with other deacetylases such as HDAC3 as well as the corepressors NcoR and ...
Company:GeneTex

Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

Description:... growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. repression of T-cell proliferation and interleukin-2 (IL-2) gene expresion, for example, occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retino...
Company:ABR-Affinity BioReagents
Repression in Biological Dictionary

Repression

Psychological repression , or simply repression , is the psychological act of excluding desires and impulses from one's consciousness and holding or subduing them in the unconscious. Since the popularization of Sigmund Freud's work in psychoanalysis, repression is now... Political r...

Histone

...s an integral component of the CoREST- human histone deacetylase complex" ... RBP1 recruits both histone deacetylase-dependent and -independent repression ... The histone H2A variant of Drosophila melanogaster, H2Av, localizes to the ... Neither H2Av accumulation nor histone H4 Lys 12 acetylation...

Exon

...ing. ... For example, mutations in exon 18 of the breast cancer BRCA1 gene cause ... PTB: A REPRESSOR OF EXON DEFINITION. MECHANISMS OF PTB repression ... The recognition of intron- exon boundaries, the splice sites, however, requires ... ...

Epigenetics

...ed out on agouti mice, and ... ... in the DNA sequence, epigenetics is reshaping the way scientists look at ... Epigenetics : Regulation Through repression ... Epigenetics and Disease ... The "more" is known as epigenetics .<p> <p> </p> <p><b></p> ... Epigenetics...
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(Date:9/19/2014)... NH 9/18/14) A leading Dartmouth researcher, working with The ... a paper published today in the Journal of ... increase the risk of melanoma. , "For the first ... length of these telomeres play a part in the ... study Mark Iles, PhD, School of Medicine at the ...
(Date:9/19/2014)... September 19, 2014 According to a ... the embattled blood-thinner Xarelto, named as defendants in several ... Pleas, have moved the court to dismiss those suits ... have sufficient connection with Philadelphia.* The cases include, for ... (No. 140304328; Pa. Comm. Pls., Philadelphia Cty.), which was ...
(Date:9/19/2014)... 19, 2014 (HealthDay News) -- U.S. military troops deployed ... skin cancer, according to a new study. ... researchers revealed. In some cases, military personnel developed blisters ... color, shape or size of their moles since being ... risk factors for skin cancer, the study authors noted. ...
(Date:9/19/2014)... Sept. 19, 2014 (HealthDay News) -- Pregnant women who live ... or low birth weight babies, a new study suggests. ... Canada, and found that expectant mothers who lived in a ... a 20 percent lower risk of very preterm birth (before ... preterm birth (30 to 36 weeks). Babies born to ...
(Date:9/19/2014)... Sept. 19, 2014 (HealthDay News) -- The U.S. Food and ... on Thursday. Trulicity is part of a class of once-a-week ... with type 2 diabetes. "Trulicity is a new ... existing treatment regimens to control blood sugar levels in the ... director of the FDA,s Office of Drug Evaluation II, said ...
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(Date:9/19/2014)... a species which over thousands of years has adapted to ... substance that makes the cold dangerous for you. , This ... , and the cold provoking substance, called nonylphenol, comes from ... is suspected of being a endocrine disruptor, but when entering ... worm,s ability to protect the cells in its body from ...
(Date:9/19/2014)... plants regulate their symbiotic relationship with soil bacteria ... the plant structure from leaves into the roots ... the roots. This collaborative study was conducted by ... the Graduate University for Advanced Studies (SOKENDAI), and ... Japan. , Legumes, an important plant family ...
(Date:9/18/2014)... A new GSA Bulletin study uses ... Rio Puerco and Chaco Wash in northern New Mexico, ... salt cedar and willow, investigators were able to precisely ... They then combined this data with aerial imagery, LiDAR, ... of these arroyos. , Arroyos are deep, oversized channels ...
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