How one virus uses mimicry to replicate successfully
(PHILADELPHIA) Both viruses and cancers subvert the growth-control machinery in a cell to serve their own needs. According to a new study, at least one virus uses mimicry to gain access to that machinery. A common target for both is a cell protein called the retinoblastoma protein, or pRb, whi...Mouse mammary tumor virus can replicate in human cells
Mouse mammary tumor virus (MMTV) - which causes mammary cancer in mice - can replicate and spread in human cells, research published this week shows. The study, published in the online open access journal Retrovirology, adds weight to the theory that MMTV might be involved in causing human breast ...IDEAL LIFE's Remote Monitoring System Benefits Rural North Carolina Communities
...he first federally-qualified health center in the nation to implement a community-based telehealth network. The newly awarded HWTF Phase II grant will replicate the program's successful Phase I in six community clinics in North Carolina. Participating community health centers include Roanoke Chowan Community H...Electronic Healthcare Network Announces Multi-State Expansion, Beginning in Buffalo, NY
...gic Health Care is very important to our strategy for rapid national growth and achieving scale in this business. We expect to begin in Ohio and then replicate our efforts in other states," said Joseph Wolfson, President and CEO of HealthTransaction Network(R). The Company has also reached agreements w...Savient Announces FDA's Advisory Panel to Review Pegloticase for Treatment-Failure Gout Patients
...g includes data from both the six-month placebo-controlled Phase 3 pivotal trials, as well as data from the open label extension (OLE) study. The two replicate six-month Phase 3 clinical trials for pegloticase were performed under the auspices of a Special Protocol Assessment (SPA) (2006). Pegloticase was gr...Carbo-Seal Valsalva Ascending Aortic Prosthesis
Description:... Carbo-Seal Valsalva AAP is the first valved graft to replicate the natural Sinus of Valsalva, encouraging the natural formation of systolic vortices....DJD II Dynamic Elbow Joint Distractor
Description:...ive motion of the elbow and to protect the articular surfaces of the elbow and collateral ligaments. Motion is allowed by a hinge which is designed to replicate the elbow's axis of rotation, while an integrated distraction mechanism prevents the articular surfaces from damaging each other. The DJD® II may ...Bigliani/Flatow The Complete Shoulder Solution
Description:...oulder replacement surgery. Backed by the clinical expertise of surgeons and decades of experience, the Bigliani/Flatow Shoulder System is designed to replicate the natural shoulder's mobility, balance, and stability with a multitude of component sizes....Scientists Replicate Hepatitis C Virus in Laboratory
For the first time, scientists have replicated hepatitis C virus (HCV) in the laboratory. The ability to replicate HCV in cell culture will allow researchers to better study the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the l...AGU journal highlights -- Aug. 6, 2009
...ming and brightening originated, how dimming and brightening affects other global environmental processes, whether current climate models successfully replicate observed patterns in dimming and brightening, and how dimming and brightening may evolve over the coming decades. Title: Global dimming and brighte...Stress signals link pre-existing sickness with susceptibility to bacterial infection
...pplement their own needs and survival requirements. By manipulating AMPK levels, scientists were able to directly influence the ability of bacteria to replicate inside of the single-celled organism, Dictyostelium . Striking similarities that exist between simple organisms like Dictyostelium and humans al...DOE-funded research projects win 46 R&D 100 Awards for 2009
...nts or finishes used on homes, cars or even bridges. The UAWS provides test results 12 times faster than other accelerated weathering systems and can replicate years of sun damage in just a few weeks. (Jointly with Atlas Material Testing Technology and the Institute of Laser Optical Technology) Power Pl...DNA template could explain evolutionary shifts
...ine. When a cell divides, it must reproduce its DNA so that each cell that results from the division has the same genetic code. That means it must replicate its DNA. During this process, an enzyme called a helicase separates the two strands, breaking the hydrogen bonds between the A T and G C base pairs....Curis and Debiopharm Sign an Exclusive License Agreement Covering the HSP90 Inhibitor CUDC-305
...nce adverse results, delays and/or failures in their strategic alliance transactions with Curis. For example, Genentech may not be able to replicate in later trials any favourable outcomes from earlier trials of GDC-0449, and Debiopharm may not be able to successfully advance CUDC-305 i...SleepQuest Signs National Contract With Aetna
...ices. "Not only can we now reach more of those suffering from these illnesses," said Koenigsberg, "but if we're successful, other insurers will surely replicate the model Aetna has provided. This could help even more people who are currently undiagnosed." For more information about SleepQuest and its serv...Amylin Announces Preliminary Tabulation of Annual Meeting Results
... new data, safety and technical issues, or manufacturing and supply issues; risks that our clinical trials will not be completed when planned, may not replicate previous results or achieve desired end-points; risks that our preclinical studies may not be predictive; risks that our NDAs for product candidates o...New rotors could help develop nanoscale generators
...magnetic fields, which play an important part in machines like electric motors and generators. The difficulty for technology at the atomic scale is to replicate this property with rotors the size of small molecules. A number of rotating molecules have already been identified, but so far molecules have not been...Amylin Responds to Eastbourne Letter
...ctations; risks that any financial guidance we provide may not be accurate; risks that our clinical trials will not be completed when planned, may not replicate previous results or achieve desired end-points; risks that our preclinical studies may not be predictive; risks that our NDAs for product candidates o...Amylin Comments on RiskMetrics Report
...ctations; risks that any financial guidance we provide may not be accurate; risks that our clinical trials will not be completed when planned, may not replicate previous results or achieve desired end-points; risks that our preclinical studies may not be predictive; risks that our NDAs for product candidates o...loxP flanked Ampicillin Selection Cassette (loxP-amp-loxP) from Gene Bridges GmbH
Description:...enome by Red/ET Recombination. The loxP-amp-loxP cassette is not linear but plasmid based (3502 bp in size). Due to its R6K origin the plasmid cannot replicate in most E.coli strains. The PCR product can therefore be used directly for downstream applications without any further purification....FRT flanked Ampicillin Selection Cassette (FRT-amp-FRT) from Gene Bridges GmbH
Description:... genome by Red/ET Recombination. The FRT-amp-FRT cassette is not linear but plasmid based (3502 bp in size). Due to its R6K origin the plasmid cannot replicate in most E.coli strains. The PCR product can therefore be used directly for downstream applications without any further purification....loxP flanked Chloramphenicol Selection Cassette (loxP-cm-loxP) from Gene Bridges GmbH
Description:...genome by Red/ET Recombination. The loxP-cm-loxP cassette is not linear but plasmid based (3301 bp in size). Due to its R6K origin the plasmid cannot replicate in most E.coli strains. The PCR product can therefore be used directly for downstream applications without any further purification....FRT flanked, Pro and Euk. Neomycin Selection Cassette (FRT-PGK-gb2-neo-FRT) from Gene Bridges GmbH
Description:...single Red/ET Recombination step. The FRT-PGK-gb2-neo-FRT template is not linear but plasmid based (3446bp in size). Due to its R6K origin it can not replicate in most E. coli strains. The PCR product can therefore be used directly for downstream applications without any further purification....