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Repeats in Medical News

Quest International Repeats Win as Siemens Healthcare Best Global Supplier of the Year

IRVINE, Calif., July 6 /PRNewswire/ -- Quest International, Inc. announced it was once again the recipient of the biennially-conferred Siemens Healthcare's Best Global Supplier of the Year Award. This is the second consecutive year the Irvine, California-based company was presented with the award...

DRE Medical Equipment Repeats as a Fast 50 Company

For the second consecutive year, Business First of Louisville has recognized DRE Medical Equipment as one of the 50 fastest growing businesses in Greater Louisville. (Vocus) November 3, 2008 -- DRE, Inc., a premier international medical and surgical equipment suppli...

Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration

Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. Scientists at E...

UP Repeats NCQA Certification in Utilization Management

BINGHAM FARMS, Mich., Oct. 19 /PRNewswire-USNewswire/ -- United Physicians, P.C., an organization of 1,900 independent doctors practicing in Southeast Michigan, has been recertified by the National Committee for Quality Assurance (NCQA) in Utilization Management. NCQA is an independent, non-pr...

Scientists Reverse Muscular Dystrophy in Mice

... messenger RNA (mRNA) in cells, which affects muscle control and other cellular functions. The original defects in the DNA translate into expanded repeats in the RNA which then bind up various cellular proteins. These include one called "muscleblind," thought to be a key factor in myotonic dystrophy. ...

Researchers estimate risk of transmission of Huntington's disease to offspring among male carriers

...e 4. Individuals with a variant of at least 36 CAG repeats will likely develop HD in their lifetime. Most individuals have a variant below 27 CAG repeats and are not at risk for the disease nor are they a...h individuals with a variant between 27 and 35 CAG repeats (called high normal) are not at risk of developing...

Your Chemist Shop Responds to Online Shopping Trends

... service online pharmacy providing patients with complete professional service, allowing them to easily fill their prescriptions online and file their repeats for quick and fast delivery too. Patients are asked to fill in a simple form to register their details at Your Chemist Shop when they first visit this...

Sleep Apnea Seems to Wear Down the Brain

... even ceases. This causes blood oxygen levels to drop and blood pressure to rise, but order is restored when the person momentarily awakens. The cycle repeats itself throughout the night. The study found that those with sleep apnea had lower cerebral blood flow velocity and notably lower blood oxygen le...

Doctors Urged to Screen Diabetics for Sleep Apnea

...collapse of soft tissue in the back of the throat during sleep. Between snores, breathing stops for a period of 10 seconds or longer, and this pattern repeats itself multiples times over the course of a night. Not only does it deprive the person of a good night's sleep, but it may increase the risk for h...

Science Fiction Has Become Reality with Remarkable Anti-Aging Treatment Breakthrough - Turning Back the Biological Clock in Aging

...e "younger" as they grow older. TA-65 doesn't just stop cell aging, but it reverses it. "It has been scientifically proven that telomeres, which are repeats of certain base pairs of DNA, are the actual "biological clock of aging cells," said Eva Hodgens, Wellness Research Chief Marketing Officer. "The shor...
Repeats in Medical Technology

Vion Pharmaceuticals Announces Initiation of a Phase I/II Trial of Cloretazine(R) (VNP40101M) in Combination with Temodar(R) in Adult Brain Tumors

...temozolomide on days 1-7 and intravenous Cloretazine(R) (VNP40101M) over 15-30 minutes 2 hours after the last dose of temozolomide on day 7. Treatment repeats every 7 weeks in the absence of disease progression or unacceptable toxicity. Correlative studies conducted as part of the trial will measure: (i) th...
Repeats in Medical Products

NanoChip Molecular Biology Workstation

Description:...i-purpose instrument that facilitates detection of known sequences, such as in the analysis of Single Nucleotide Polymorphisms (SNPs) and Short Tandem repeats (STRs) using the NanoChip Electronic Microarray. The unique, open-architecture design permits researchers to define, select and build their own test p...
Company:Nanogen, Inc.

Digistim 2 Plus Nerve Stimulator

Description:...nter position) Double Burst : 2 60-ms bursts of 50 Hz separated by .75 s; repeats every 10 s Twitch: 1 s (1 pulse/s); single or repeat Tetanus: 50 Hz (5...100 pulses/s) Train-Of-Four: Single (4 pulses/2 s); repeat (4 pulses/2 s; repeats every 10 s) Output Current: Adjustable from 0-70 mA (HI range) 0-6.0 mA (...
Company:CCR Medical

Digistim II Nerve Stimulator

Description:...1 pulse/s); 10 s (1 pulses/10 s) Tetanus: 50 Hz (50 pulses/s) or 100 Hz (100 pulses/s) Train-Of-Four: Single (4 pulses/2 s); repeat (4 pulses/2 s; repeats every 10 s) Output Current: Adjustable from 0-70 mA(HI range) 0-6.0mA (LO range) Stimulus Pulse: Square Wave Monophasic pulses (200-us duration) ...
Company:CCR Medical

Digistim 3 Plus Nerve Stimulator

Description:...imulus pulses. Double Burst : 2 60-ms bursts of 50 Hz separated by .75 s; repeats every 10 s Twitch: 1 s (1 pulse/s); 2 Hz (2 pulses/s) Tetanus: 50 Hz (50 pulses/s) or 100 Hz (100 pulses/s) Train-Of-Four: 4 pulses/2 s; repeats every 10 s Output Current: Adjustable from 0-70 mA (HI range) 0-6.0mA (LO...
Company:CCR Medical

DigiStim III Nerve Stimulator

Description:...witch: 1 s (1 pulse/s); 2 Hz (2 pulses/s); 10 s (1 pulse/10 s) Tetanus: 50 Hz (50 pulses/s) or 100 Hz (100 pulses/s) Train-Of-Four: 4 pulses/2 s; repeats every 10 s Output Current: Adjustable from 0-70 mA Stimulus Pulse: Square Wave Monophasic pulses (200-us duration) Indicators: Digital LCD show...
Company:CCR Medical

BenchMark® XT

Features:... or your own Eliminate over 80% of the labor required by other slide staining systems Deliver up to 60 slides in a single 8 hour shift Reduce repeats with standardized slide processing Automate any or all slide preparation stepsbaking, cell conditioning deparaffinization, staining ...
Company:Ventana Medical Systems Inc.
Repeats in Medical Dictionary

Hiccup

...hiccup or hiccough, is the spasmodic contraction of the diaphragm that repeats several times per minute. In humans, the abrupt rush of air into the lungs...ed HICK-up,) is a spasmodic contraction of the diaphragm that typically repeats several times per minute. Why do we hiccup and what the heck are hic...

Circadian

... Rhythm Disorder. ... The term circadian comes from Latin roots: circa(about) and dies (day). A circadian rhythm is an endogenous rhythm that repeats with a period of about 24 hours. ... Circadian rhythms are physical, mental, and behavioral changes that follow a ... The study of circadian r...
Repeats in Biological News

Biologists discover link between CGG repeats in DNA and neurological disorders

MEDFORD/SOMERVILLE, Mass. Researchers have long known that some repetitive DNA sequences can make human chromosomes "fragile," i.e. appearing constricted or even broken during cell divisions. Scientists at Tufts University have found that one such DNA repeat not only stalls the cell's replication...

Researchers gain insight into mechanism underlying Huntington's

... other neurodegenerative or neuromuscular disorders caused by trinucleotide repeats (or TNRs) in DNA. The research, performed in the laboratory of Dr. Guo-M...plication and/or DNA repair must be involved. Two key TNRs, CAG and CTG repeats associated with Huntington's disease and myotonic dystrophy, respectively ...

The tiny difference in the genes of bacteria

...t. As a result, the researchers receive, for example, six red fragments binding a tandem of six repetitions. Then, the researchers analyzed the tandem repeats marked with dyed fragments: Every bacteria strain differs in pattern and size of the measured tandem repeats. "With this method, we are able to di...

The tiny difference in the genes of bacteria

...t. As a result, the researchers receive, for example, six red fragments binding a tandem of six repetitions. Then, the researchers analyzed the tandem repeats marked with dyed fragments: Every bacteria strain differs in pattern and size of the measured tandem repeats. "With this method, we are able to di...

Measuring intellectual disability

...imes, decreasing levels of the FMRP protein. Current tests for fragile X syndrome determine the presence of the mutation by measuring the number of repeats at the DNA and mRNA level; however, the lack of a quantifiable test to determine FMRP protein levels has prevented direct correlation between FMRP pro...

New piece found in the puzzle of epigenetics

...the RNA polymerase II enzyme the carboxy-terminal domain is involved in deciding which kinds of RNA are formed. In humans this domain consists of 52 repeats of a sequence of seven amino acids. For RNA synthesis the determining factor is whether and how specific amino acids of this region are modified bioch...

Saved by junk DNA

...would foster such a wasteful system'. Unstable repeats The international team of scientists found that stretches of tandem repeats influence the activity of neighboring genes. The repeats determine how tightly the local DNA is wrapped aro...

Small molecules might block mutant protein production in Huntington's disease

...ington's and Machado-Joseph are fatal inherited diseases caused by abnormal repeats of a small segment in a person's DNA, or genetic code, represented by the l...ed ataxin-3. A person with Huntington's can have up to 100 CAG repeats. CAG repeats are involved in several other neurodegenerative diseases, including Fragile...

New hope for treatment of neurodegenerative disorder

...tween six and 34 CAG repeats. Any strand of DNA possessing more than 40 CAG repeats indicates the carrier will develop Huntington disease, according to the researchers. Indeed, the more repeats of CAG, the earlier the disease manifests itself and the more devastating t...

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

...e has a sequence of between six and 34 CAG repeats, the abnormal gene contains many more. In fact, any stretch of DNA containing more than 40 of these repeats ensures that its bearer will develop Huntington'sthe greater the number of repeats, the earlier the disease strikes and the greater its ferocity. The ...
Repeats in Biological Technology

The Next Economy - Market Collapses Drive Long-Term Growth

...pered and has played a huge part in driving the US economy for the last fifty years. It has completely revolutionized global manufacturing! History repeats itself in many ways. Its important to remember that speculation driven technology revolutions often appear to fail fast in the short term. Yet in real...

CEO of healthcare group still hopeful IT will save employers money

...on other wasteful spending, he said. It is not unusual for an employee to go to one setting, have a test, and get referred to a specialist who then repeats the test because the results didn't follow the patient. "Things like that can have very immediate impacts on the cost of care," Lieber said, "and so I...

SNPs Powerful Tools for Association Studies

...ragment length polymorphisms (RFLPs), short tandem repeats (STRs), and SNPs have played significant roles in ...the sequences of interest. Short tandem repeats The mid- to late-80s brought the disco...such as (CA)n and (CAG)n, where n is the number of repeats all of which are flanked by unique sequences. Alth...

Performance of Ad-A-Gene Cyclic AMP Response Element-Nitroreductase (CRE-NTR): an adenoviral vector gene delivery system

...several key signal transduction pathways regulating cAMP. We have exploited the binding of CREB to CRE through an adenoviral construct containing four repeats of CRE upstream of a minimal promoter and NTR (CRE-NTR). Upon adenoviral vector transduction of target cells, the CRE-NTR gene becomes transiently exp...

Transformation of Filamentous Fungi by High-Voltage Electroporation

...tions showed the restriction patterns expected from the restriction map of pAN7-1. Each transformant most likely contains tandem repeats of the vector. Hybridization of undigested DNA occurred only in the high molecular weight genomic band (UC), suggesting that pAN...

Real-Time PCR: General Considerations, Rev A

...ny template secondary structures Avoid templates with long (>4) repeats of single bases Maintain a GC content of 5060% Anal...ween 50 and 65C Eliminate secondary structure Avoid repeats of Gs or Cs longer than 3 bases Place Gs and Cs on ends of prim...

The Gradient Feature: Use in Optimization of Allelic Discrimination Assays, Rev B

... followed the amplification. Reactions were incubated first at 95C for 60 sec and subsequently at 55C for 60 sec, followed by 80 repeats of heating for 10 sec starting at 55C with 0.5C increments. Optimization of Annealing Temperature for SNP Detection Using a TaqMan ...

Real-Time PCR/Melt-Curve Analysis: SNP Detection With FRET, Rev A

...re an initial denaturation step of 95C for 3 min, followed by 45 repeats of 95C for 10 sec and 50C for 40 sec. A melt-curve protocol imme...plification with 95C for 1 min and 50C for 1 min, followed by 70 repeats of heating for 10 sec, starting at 50C with 0.5C increments. ...

siRNA Expression Vectors with Selectable Markers

...iRNA (See Why RNA Polymerase III Promoters? in sidebar). The insert that encodes this hairpin is designed to have two inverted repeats separated by a short spacer sequence (Figure 1). One inverted repeat is complementary to the mRNA to which the siRNA is targeted...

siRNA Design Guidelines

...ing the expressed siRNA. Most of the designs had two inverted repeats separated by a short spacer sequence and ended with a string ...election of siRNA target sequence, the length of the inverted repeats that encode the stem of a putative hairpin, the order of the ...
Repeats in Biological Products

Mouse Anti-Mucin 3 (MUC3) Ab-2 Monoclonal Antibody, Unconjugated, Clone 1143/B7 from Lab Vision

Description:...tum, and to a lesser extent in breast, lung and salivary gland tissues. Comments: Ab-2 shows no cross-reaction with MUC1 and MUC2. Epitope: Tandem repeats of the human MUC3 Immunogen: MUC3 tandem repeat peptide Positive Control: Colon carcinoma. Cellular Localization: Cell membrane...
Company:Lab Vision

GeneChoice TEMPase II DNA Polymerase from GeneChoice, Inc.

Description:...minates nonspecific products due to inactivity at room temperature • Excellent specificity allows extension through DNA regions which contain repeats and secondary structures • Leaves an 'A' overhang TEMPase II is a chemically modified form of GeneChoice DNA Polymerase that remains ina...
Company:GeneChoice, Inc.
Repeats in Biological Definition

Centromere

...equence within individual repeat elements is similar but not identical. In humans, the centromeric repeat unit is called α-satellite. However, repeats of α-satellite are not sufficient to cause the assembly of a kinetochore, and there are functioning centromeres with no α-satellite DNA. ...

DNA

...a process called DNA profiling or genetic fingerprinting. In DNA profiling the relative lengths of sections of repetitive DNA, such as short tandom repeats and minisatellites are compared. DNA profiling was developed in 1984 English geneticist Alec Jeffries , and was first used in 1986 in the End...

Genetic fingerprinting

...tellites . Two unrelated humans will be likely to have different numbers of microsatellites at a given locus . By using PCR to detect the number of repeats at several loci, it is possible to establish a match that is extremely unlikely to have arisen by coincidence. Genetic fingerprinting is used in fo...

Genetic recombination

... between any two double helices of DNA which are very close in sequence and come into contact with one another. Thus, crossover may occur between Alu repeats on the same chromatid, or between similar sequences on two completely different chromosomes. These processes are called unbalanced recombination. U...

Microsatellite

...any times within the genome of an organism. Many repeats tend to be concentrated at the same locus. In a ...ence of "TAGTAGTAGTAGTAGTAGTAG..." The number of repeats at a particular locus is hypervariable (highly ... high frequency of loss or insertion of additional repeats by confusing the DNA replication machinery. Self...

Prion

...comes from detailed biochemical analysis of yeast prion proteins. A typical yeast prion proteins contain a region ( protein domain ) with many repeats of the amino acids glutamine (Q) and asparagine (N); these Q/N-rich domains form the core of the prion's structure. Ordinarily, prion domains are ...

Repeated sequence (DNA)

...ces, one can distinguish two main types of repeated sequence : Tandem repeats : Satellite DNA , Minisatellite , Microsatellite ; Interspersed repeats : SINE ( S hort IN terspersed E lements), LINE ( L ong IN terspers...
Repeats in Biological Dictionary

Repeats

The repeats are tandem - they are clustered together and oriented in the same direction. Individual repeats can be removed from (or added to) the VNTR via ... Tandem repeats occur in DNA when a pattern of two or more nucleotides is repeated and the repetitions are directly adjacent to ...

Inverted Repeats

An inverted repeat (or IR) is a sequence of nucleotides that is the reversed complement of another sequence further downstream. inverted repeat with spacer. palindromic repeat . mirror and everted repeats [edit] See also ... Tandem repeats ... Interspersed repeats ......

Direct Repeats

Direct repeats are a type of genetic sequence that consists of two or more repeats of a specific sequence. local direct repeats with spacer. inverted repeats . global inverted repeat . local inverted repeat ... Tandem repeats ... Interspersed repeats ... The leng...

VNTR

...arge range of copy numbers, even among highly ... Variable-Number Tandem repeats ( VNTR's ) are well known for their high mutation ... Some VNTR's , howe...ts with ... One type of minisatellites is called variable number of tandem repeats ( VNTR ) ... VNTR . Reference Laboratories. Reference Materials. Monoc...

Triplet repeat expansion

... a dynamic or unstable mutation ... Disease. 1.2 Expansion of Triplet repeats ... Lesson 1: Triplet Repeat Expansion (1 of 3) ... The triplet ...1060 (2009) ... driving triplet repeat contraction ... ... Triplet repeats in Noncoding Regions Fragile X syndrome (CGG repeat ) Fragile ... is cause...

Transposon

...n humans is the Alu sequence. ... After the transposon is ligated to the host DNA, the gaps are filled in by ... This creates identical direct repeats at each end of the transposon . ... Transposon summary with 15 pages of encyclopedia entries, essays, summaries, research information, and more...

Telomere

...Negative regulator of telomere length (telomerase-dependent pathway) ... Tankyrase-mediated ADP-ribosylation of TRF1 inhibits binding to telomere repeats ... ...

Telomerase

... Telomerase is an enzyme that adds specific DNA sequence repeats to the 3' end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. The telomeres contain condensed DN...

Tandem repeat sequence

... ... tandem repeats in strings (e.g. DNA sequences ) can ... seque...quence , we systematically cataloged all tandem repeats with periods ... of the consensus sequence (bot...eat from ALL TRs ... Polymorphism of tandem repeats within protein-coding sequences is known to ......

Tandem repeat sequences

... ... Computer Science, tandem repeats in strings (e.g. DNA sequences ) can be ... (L...equence on ... ... Computer Science, tandem repeats in strings (e.g. DNA sequences ) can be ... A t... Poly-A Sequences and Heteroplasmic Tandem repeats . David A. Ray. 1. and ... 7.—Aligned sequences ...
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Breaking Medicine News(10 mins):Health News:Europe Vitamins (Nutraceuticals) Market is Expected to Reach $1,202.08 Million in 2018 - New Report by MicroMarket Monitor 2Health News:Europe Vitamins (Nutraceuticals) Market is Expected to Reach $1,202.08 Million in 2018 - New Report by MicroMarket Monitor 3Health News:Europe Vitamins (Nutraceuticals) Market is Expected to Reach $1,202.08 Million in 2018 - New Report by MicroMarket Monitor 4Health News:Europe Vitamins (Nutraceuticals) Market is Expected to Reach $1,202.08 Million in 2018 - New Report by MicroMarket Monitor 5Health News:Europe Bio Fertilizer Market is Expected to Reach $4,582.2 Million in 2017 - New Report by MicroMarket Monitor 2Health News:Europe Bio Fertilizer Market is Expected to Reach $4,582.2 Million in 2017 - New Report by MicroMarket Monitor 3Health News:Europe Bio Fertilizer Market is Expected to Reach $4,582.2 Million in 2017 - New Report by MicroMarket Monitor 4Health News:Statin use decreases the risk of Barrett's esophagus 2Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 5Health News:Semiconductor IP Market Estimated to Reach $5.63 Billion by 2020 – New Report by MarketsandMarkets 6Health News:Vanderbilt-led study identifies genes linked to breast cancer in East Asian women 2
(Date:7/23/2014)... sulfur-oxidizing bacterial group called SUP05 will play an increasingly ... world,s oceans as oxygen minimum zones expand, according to ... the National Academy of Sciences . , University of ... anoxic fjord, Canada,s Saanich Inlet, to chart how microbial ... "Our study paints a very detailed picture of how ...
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Breaking Biology News(10 mins):Research charts the ecological impact of microbial respiration in the oxygen-starved ocean 2MedNet Appoints Clareece West As Chief Operating Officer 2
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