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Reovirus in Medical News

Scientists Develop a Harmless Multi-Tasking Reovirus

For the past two years, researchers at Oncolytics Biotech have been developing a harmless virus as a potent cancer killer//, but they have also been accumulating data that suggests in addition to directly killing tumor cells, the reovirus may prime the immune system to mount a separate, powerful an...

Harmless Virus May Be Deadly to Breast Cancer

... reovirus seeks out and destroys tumor cells, researchers sa...Canadian researchers report. "We suspected that reovirus might be effective against cancer stem cells, beca...id. Lee noted that he and his colleagues tested reovirus on fresh breast cancer tissue removed from a patie...

Cedars-Sinai Medical Center opens patient trial of virus that attacks brain cancer cells

...inated by the body within two weeks. But while the reovirus (respiratory enteric orphan virus) may be harmless...Ras pathway) that controls key cell functions. The reovirus is able to infect and kill cancer cells that have ..., developed a therapeutic drug, REOLYSIN, from the reovirus and are conducting multicenter clinical trials for...

Common Virus Enhances Cancer-Fighting Ability of Standard Chemotherapy Drugs

...chemotherapy drugs. In general, the combination of reovirus with cisplatin, gemcitabine, mitomycin or vinblast...ar interest to the researchers, the combination of reovirus and paclitaxel, a common chemotherapy drug, was un...reovirus. The data suggest that the combination of reovirus and paclitaxel may help in promoting cell-death si...

Cancer-Killing Viruses Employ Multiple Mechanisms

... recently however, it has been discovered that the reovirus may also have the potential to prime the body’s ow... “We’ve understood the mechanism of action of reovirus replication in cancer for a number of years,” expl...irus was gone.” Immunologic work now suggests that reovirus exposure is “educating” the immune system to recog...

Virus Combats Brain Tumour

...n a set of experiments involving cancer cell lines grown in the laboratory, reovirus destroyed cancer cells in 20 out of the 24 cell lines. It was also found th...Ninety days after being treated, the majority of the mice treated with live reovirus were still alive, but all of the animals injected with the dead virus had d...
Reovirus in Medical Technology

Oncolytics Biotech(R) Inc. Announces Publication of Research on Synergistic Activity of Reovirus and Chemotherapy in NSCLC

CALGARY, July 16 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY ) ('Oncolytics') reported today that Dr. Shizuko Sei et al. published the results of their work examining reovirus and chemotherapy against human non-small cell lung cancer (NSCLC). The paper, entitled "Syn...

Oncolytics Biotech Inc. Announces Start of Patient Enrolment in Translational Clinical Trial Investigating REOLYSIN(R) in Patients with Metastatic Colorectal Cancer

...re now being sponsored by our collaborators." The primary objectives of the trial are to assess the presence, replication and anti-cancer effects of reovirus within liver metastases after intravenous administration of REOLYSIN(R) by examination of the resected tumour. Secondary objectives include assessing ...

Oncolytics Biotech Inc. Collaborators to Present Reovirus/Gemcitabine Combination Research at AACR Annual Meeting

...y that an abstract covering preclinical work using reovirus in combination with gemcitabine is available today...tated Human HCT116 Xenografts." The combination of reovirus and gemcitabine was more effective than gemcitabine or reovirus alone at killing human colon cancer cells in a mou...

Oncolytics Biotech Inc. Research Collaborators Demonstrate Reovirus/Gemcitabine Combination Has Synergistic Effect Against Human Colon Cancer Cell Lines

...ncolytics Biotech Inc. ("Oncolytics") announces that a poster by Dr. Maureen E. Lane et al. of , New York, entitled "In Vivo Synergy between Oncolytic reovirus and Gemcitabine in Ras-Mutated Human HCT116 Xenografts" is scheduled to be presented today at the American Association for Cancer Research (AACR) Annu...

Oncolytics Biotech Inc.'s Research Collaborators to Present REOLYSIN Clinical Trial Data at ASCO Conference

...nal results of Oncolytics' U.K. Phase I systemic administration trial. The poster, entitled "Final Results of a Phase I Study of Wild-Type Oncolytic reovirus Administered Intravenously to Patients with Advanced Cancer" is scheduled to be presented by Dr. James Spicer of The Royal Marsden Hospital and The In...
Reovirus in Biological News

Oncolytics Biotech, Inc. announces publication of research

...mor efficacy and safety of various combinations of reovirus and cyclophosphamide in vivo. The paper, entitled...cutaneous Tumors following Intravenous Delivery of reovirus appears online in the January 1, 2008 issue of Cli...or, to enhance the delivery and replication of the reovirus when delivered intravenously. After testing vario...

Dealing deadly cancers a knockout punch

... in human clinical trials. Oncolytics' proprietary reovirus formulation, Reolysin®, is active against numerous...ttsdale, Arizona, several presentations focused on reovirus efficacy alone or in combination with standard che...nvestigators examined the tumor-killing ability of reovirus plus cisplatin, a standard chemotherapy agent, in ...
Reovirus in Biological Technology

Oncolytics Biotech(R) Inc. Research Collaborators Present Glioma Reovirus Research at ASV Annual Meeting

CALGARY, July 15 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY ) announced today that a poster presentation by Dr. Jacqueline Parker et al. entitled "Anti-Tumor Activity of Reovirus is Synergistically Enhanced in Combination with Temozolomide and Low Dose Irradiation i...

Oncolytics Biotech(R) Inc. Collaborators Present Reovirus Research at Replicating Oncolytic Virus Meeting

CALGARY, March 23 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY ) announced results of two preclinical studies that were presented at the Fifth International Meeting on Replicating Oncolytic Virus Therapeutics. The meeting was held in Banff, Alberta from March 18th to ...

Oncolytics Biotech(R) Inc. Announces Reovirus Research to be Presented at AACR Annual Meeting

CALGARY, March 16 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY ) announced today that abstracts covering research with reovirus (REOLYSIN(R)) are available on the American Association for Cancer Research (AACR) website at www.aacr.org , and on the Oncolytics website ...

Oncolytics Biotech Inc. Collaborators Present Reovirus and Melanoma Research at EORTC-NCI-AACR Symposium

CALGARY, Oct. 23 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced today that Dr. Shizuko Sei of SAIC-Frederick, Inc., delivered a poster presentation entitled "In Vivo Efficacy and Replication Dynamics of Intravenously Administered Oncolytic Reovirus in Nude ...

Oncolytics Biotech Inc. Collaborators to Present Reovirus Research at ASGT Meeting

CALGARY, May 30 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced today that two presentations covering preclinical work using the reovirus are scheduled to be delivered by Dr. Richard Vile of the Mayo College of Medicine, Rochester, Minnesota, at the American...

Oncolytics Biotech Inc. Announces Journal of Immunology Publication on Reovirus Activation of Dendritic Cells

CALGARY, April 23 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that Prof. Alan Melcher and his research group at St. James's University Hospital in Leeds, U.K. published the results of their work with reovirus in the May 1, 2008 online ...

Oncolytics Biotech Inc. Announces Gene Therapy Publication on Reovirus Treatment for Melanoma

CALGARY, April 16 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that Prof. Alan Melcher and his research group at St. James's University Hospital in Leeds, U.K. published the results of their work in the April 10 online issue of Gene The...

Oncolytics Biotech Inc. Collaborators Present Reovirus Research for Multiple Myeloma at AACR Annual Meeting

CALGARY, April 15 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced that an oral presentation by Dr. Chandini Thirukkumaran of the Tom Baker Cancer Centre, Calgary, entitled "Targeting Multiple Myeloma with Oncolytic Viral Therapy" was presented today at the A...

Oncolytics Biotech Inc. Collaborators Present Reovirus Research for Pediatric Sarcomas at AACR Annual Meeting

CALGARY, April 15 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced that a poster presentation by Dr. Anders Kolb of the Nemours Center for Childhood Cancer Research entitled "Radiation in Combination with Reolysin for Pediatric Sarcomas" was presented today a...

Oncolytics Biotech Inc. Collaborators to Present Reovirus Research at AACR Annual Meeting

CALGARY, March 13 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced that two abstracts covering preclinical work with reovirus are available today on the American Association for Cancer Research (AACR) website at http://www.aacr.org, and on the Oncolytics we...
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