Industry Experts and Global Regulators to Discuss Oligonucleotide-Based Therapeutics Issues
The Drug Information Association (DIA), in collaboration with the FDA, Oligonucleotide Therapeutics Society, Health Canada, and the American Association of Pharmaceutical Scientists, will host the 2nd Conference on Oligonucleotide-based Therapeutics (September 22 - 24; Falls Church, VA). ...Blue Shield Settlement with Regulators Timed to Fend Off L.A. City Attorney's Lawsuit
SANTA MONICA, Calif., July 17 /PRNewswire-USNewswire/ -- Governor Schwarzenegger and regulators announced a company-friendly settlement with Blue Shield today on the heels of a new lawsuit filed by the Los Angeles City Attorney that could cost the company $1 billion for retroactively canceling...Neuronal regulators offer potential targets for cancer
Boston, Mass. (March 19, 2008) -- Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. "Braininess" also causes problems for cells. When a breast cell begins making the proteins normally produced in neurons, for example, it can acquire can...Deficient regulators in the immune system responsible for type 1 diabetes
Montreal, 24th January 2008 - The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases. The gradual reduction in their regulating capacity seems to play a critical role in the onset of type 1 diabetes, as demonstrated in...AARP Calls on State Regulators to Reject Proposed Settlement of TXU Buyout
'Who's looking out for everyday Texans?' AUSTIN, Texas, Oct. 5 /PRNewswire-USNewswire/ -- AARP today said a proposed settlement of the record-setting $45 billion buyout of TXU amounts to one more backroom deal that ignores the interests of residential customers and in essence e...Squeamish Colorado Dental Patients Get Drilled By Self-Interested Regulators
Colorado dental patients are being harmed by the very State regulators who are appointed by Governor Bill Ritter to protect them, a newly formed group, Holorado, contends. Self-interested Colorado regulators have "mile-highjacked the process" to place their own financial interests ahea...Promising new TB drug given special status by US and European regulators
What: Approximately one-third of the worlds population is infected with Mycobacterium tuberculosis, the bacterium that causes TB, and an estimated 1.6 million people died of the disease in 2005. Currently, TB patients must adhere to a complex treatment regimen over a six- to nine-month period. Thi...Researchers Urge Regulators to Rethink Strategies for Soot Emission
Carnegie Mellon University researchers say government officials need to adopt new ways of measuring and regulating the fine particles of smoke and soot so endemic// to serious health problems and the global warming crisis. In a March 2 article published in the journal Science, professors All...New Study Challenges How Regulators Determine Risk
A new study provides the strongest evidence yet that a key portion of the traditional dose-response model used in drug testing and risk assessment// for toxins is wrong when it comes to measuring the effects of very low doses. Edward J. Calabrese, a scientist at the University of Massachusetts...Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study
...and regulations affecting our U.S. and international businesses, including regulations of the U.S. Food and Drug Administration and foreign government regulators and tax obligations and risks; the impact of temporarily suspending U.S. distribution of one of our key hip replacement products; product liability an...Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia
...and headaches. Sodium oxybate has the potential to induce respiratory depression and neuropsychiatric events. Sodium oxybate has not been evaluated by regulators for the treatment of fibromyalgia and is not approved for this use. Additional safety information for Xyrem, including black box warnings, can be foun...Entremed Presents Results of ENMD-2076 Phase 1 Study in Advanced Cancer Patients
...NMD-2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over-expressed in human cancers. ENMD-2076 also targets the Flt-3 and FGFR3, kinases which have been shown t...Pharmasset Voluntarily Halts Clinical Studies with Clevudine in Hepatitis B Infected Patients
...e to collect safety data and to monitor patients after discontinuation of clevudine in the QUASH studies, but does not plan to submit study results to regulators as pivotal studies. Clevudine was licensed from Bukwang Pharmaceuticals of South Korea, where the drug is marketed under the trade name Levovir. ...Prometheus and Rosetta Genomics Announce License and Collaboration Agreement
...particles and heavy metals. About MicroRNA MicroRNAs (miRNAs) are recently discovered, naturally occurring, small RNAs that act as master regulators and have the potential to form the basis for a new class of diagnostics and therapeutics. Since many diseases are caused by the abnormal activity of p...New molecular regulators of hyperthyroidism and goiter
The thyroid gland has an important role in determining how much energy the body burns. Thyroid gland functions are regulated by a hormone known as thyroid-stimulating hormone (TSH). Increased levels of TSH, as well as increased signaling through the receptor for TSH, result in hyperthyroidism (cha...Small molecules mimic natural gene regulators
ANN ARBOR, Mich.---In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should. Scientists at the Un...Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine. Though mult...Improved air quality during Beijing Olympics could inform pollution-curbing policies
...affic density and encouraging public transportation can have a significant impact on local air quality. "We hope our study can help or advise local regulators and policymakers to adopt long-term sustainable emission controls to improve air quality," Zhang said. "That's our mission." Published online July ...Carnegie Mellon team makes sequestration recommendations
...ogical sequestration. Specific recommendations include: Amend the Safe Drinking Water Act to direct Underground Injection Control (UIC) program regulators to create adaptive, performance-based rules for geologic sequestration, and to include mechanisms to resolve conflicts between multiple environmental ...Iowa State University researchers develop process for 'surgical' genetic changes
...rch from the lab to the field. Wright and Townsend hope the precision of this technique will speed the regulatory process. "In the random process, regulators would say, 'You really don't know what you're doing,'" said Townsend. "With this new technology, we can tell them, 'The genome looks like this, this i...UH team analyzes Hurricane Ike's effects on waterways, fish contamination
...h project being conducted at the University of Houston may offer important information about the effects of Hurricane Ike on pollution levels and help regulators determine whether existing fish-consumption advisories remain appropriate. With this year's storm season under way, the UH engineering team's proje...Canadian researchers set to study impact of nanomaterials on aquatic ecosystems
...n use the knowledge gained to properly engineer their products with reduced environmental impact." The research resulting from this study will help regulators understand the interaction of new molecules within our ecosystem, and inform and facilitate the development of sound regulatory policies in this area....Stanford researchers publish comprehensive model for medical device development
...n healthcare innovation," says Pietzsch. "It is our aim to contribute to a greater understanding of such differences, particularly as policymakers and regulators work to design the least burdensome approaches to medical device regulation." The article emerged from research performed by the authors as part of...Infant formula adulteration with melamine underscores need for better detection methods
...ivation for faking protein content can, unfortunately, be compelling. Rigorously defined quality standards and test methods can give manufacturers and regulators powerful tools to catch and discourage bad actorshelping to restore a shaken public confidence." Some have separated considerations of "quality" fr...Oncothyreon appoints Diana Hausman as Vice President of Clinical Development
...on of the risks and uncertainties associated with Oncothyreon, you are encouraged to review the official corporate documents filed with the securities regulators in the United States on U.S. EDGAR and in Canada on SEDAR. Oncothyreon is under no obligation to (and expressly disclaims any such obligation to) upda...Oncothyreon announces presentation of long-term Stimuvax data at World Conference on Lung Cancer
...on of the risks and uncertainties associated with Oncothyreon, you are encouraged to review the official corporate documents filed with the securities regulators in the United States on U.S. EDGAR and in Canada on SEDAR. Oncothyreon is under no obligation to (and expressly disclaims any such obligation to) upda...Zimmer Launches New Medical Education and BioSkills Training Program
...and regulations affecting our U.S. and international businesses, including regulations of the U.S. Food and Drug Administration and foreign government regulators and tax obligations and risks; the impact of temporarily suspending U.S. distribution of one of our key hip replacement products; product liability an...Wyeth Announces Stockholder Approval of Pfizer Merger at 2009 Annual Meeting
...bject to necessary global regulatory approvals and other customary closing conditions. On July 17, 2009, an important condition was met when European regulators announced that they had approved the merger. A closing date for the merger has not been announced, but the companies continue to expect the transacti...CEL-SCI Signs Definitive Agreement to Raise $5 Million in Registered Direct Offering
... the design and progress of clinical trials; safety and efficacy of the products being tested; action, inaction or delay by the FDA, European or other regulators or their advisory bodies; and analysis or interpretation by, or submission to, these entities or others of scientific data); uncertainties regarding t...Oncothyreon announces initiation of Phase 3 trial of Stimuvax in breast cancer
...on of the risks and uncertainties associated with Oncothyreon, you are encouraged to review the official corporate documents filed with the securities regulators in the United States on U.S. EDGAR and in Canada on SEDAR. Oncothyreon is under no obligation to (and expressly disclaims any such obligation to) upda...Greenway Medical Technologies To Display Live Interoperability Implementations at 2009 DIA Show
... Industry Leading Health IT Providers Collaborate to Demonstrate Interoperability with Clinical Sites, Research Sponsors and regulators through Utilization of RFD Standard CARROLLTON, Ga., June 19 /PRNewswire/ -- Greenway Medical Technologies, a leading provider of an integrated e...Oncothyreon appoints Scott Peterson as Vice President of Research and Development
...on of the risks and uncertainties associated with Oncothyreon, you are encouraged to review the official corporate documents filed with the securities regulators in the United States on U.S. EDGAR and in Canada on SEDAR. Oncothyreon is under no obligation to (and expressly disclaims any such obligation to) upda...Human BMP-5 ELISA development Kit, DuoSet Economy Pack from R&D Systems
Description:... are at least 20 structurally and functionally related BMPs, which are members of the TGF-beta superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. They are also involved in embryogenesis and morphogenesis of various tissues and organs. BMPs regulate the growth, di...Porcine Leptin ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description:...mones do not work in the short term, the long-term administration both in vivo and in vitro indicates that these two hormones may be some of the major regulators of leptin production by adipose tissue. Without an understanding of leptin regulation and how to circumvent leptin resistance, the use of leptin to t...