A new mechanism of regulating RNA degradation
As any dedicated video game player knows, the first requireme...Depression gene may weaken mood-regulating circuit
A brain scan study suggests that a suspect gene may increase susceptibility to anxiety and depression* by weakening a circuit for processing negative emotion. People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well the circuit was connected accounted for nearly 30 percent of their anxious temperament, researchers at th...Mechanism regulating tooth shape formulation found
One of the remaining challenges for evolutionary developmental studies of mammals, whose evolution is best known from their teeth, is how their tooth shape is altered during development. Researchers of the University of Helsinki together with their Japanese colleagues from the University of Kioto now propose a 'balance of induction' mechanism directing the placement of tooth shape features called...Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation
Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma. A research team led by Shyam Biswal, PhD, at the Johns Hopkins Bloomberg School of Public Health found the absence of Nrf2 exacerbated allergen-mediated asthma in mice models. The study’s findings, published in the July 4, 2005, edition of the Journal of Experimental Medicine, may hold therapeuti...Protein's role in regulating cell death sets direction for cancer research
A protein called calpain can be the key either preventing or promoting the cell death, a Queen's University study has found. "This work provides proof in principle that pharmacological inhibition of calpain may be used to block cell death in situations where this is not desirable, such as in neuronal cells of Alzheimer's or Parkinson's patients, but to promote cell death in cancer cells w...Substance P May Pre-empt VIP in Regulating Temperature
An elusive neurotransmitter pathway in the skin may have been isolated by University of Oregon researchers, a discovery that, if confirmed, //would be a leap forward in understanding how temperature regulation occurs. In other words, they may have found a major player in the machinery that allows people to release body heat and stay cool. Experiments involving 11 young men and women lo...New Platform for Regulating Expression of Therapeutic Genes Unveiled
A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented today at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle. Carefully regulating gene expression is crucial to the success of gene and cell therapy. For many applications, gene transfer is being employed to en...Appetite-regulating Peptides Influence Alcohol Cravings
A new study has confirmed that appetite-regulating peptides leptin and ghrelin influence alcohol cravings for some alcoholics. Craving, a powerful urge to drink, is an important contributor to the development and maintenance of alcoholism. Professor Otto Lesch of the University of Vienna has divided patients of alcohol dependence into four groups Type 1 that refers t...Hi-Lo® Tracheal Tube with Lanz® Pressure Regulating Valve
Description:Indications For Usage: Used to automatically maintain a low intracuff pressure during long-term intubations....