Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million
In recent years, health professionals and the general public alike have been acutely aware of the potential ravages that could result from a flu pandemic. Although many people might still recall the pandemics of 1968 and 1957, it is the infamous 1918-1920 pandemic--and the possibility of a recurrence on that scale--that causes the most trepidation. Strangely, researchers still don't kno...Pourquié lab identifies genes involved in formation of vertebral precursors
Mary Lee Dequeant, Ph.D., a Predoctoral Researcher at the Stowers Institute for Medical Research, and Olivier Pourquié, Ph.D., Stowers Institute Investigator and an investigator with the Howard Hughes Medical Institute, are the first and last authors, respectively, on a paper that identifies a network of cyclic genes that shed light on the molecular basis of spine formation in the embryo. <...Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration
Scientists have successfully transplanted light-sensing cells called photoreceptors directly into the eyes of mice and restored their visual function. The achievement is based on a novel technology in which the cells are introduced at a particular stage in their development. It was carried out at the London Institute of Ophthalmology using a novel approach developed at the University of...Adding radiation decreases breast cancer recurrence
Radiotherapy after breast conserving surgery for breast cancer reduces recurrence and prevents development of additional breast tumors in older women with early stage breast disease, according to a new study. Published in the March 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that women also benefit from the recommended five years of tamoxife...Precursor miRNAs for Successful miRNA Functional Studies
miRNA target site identification and validation Screening for miRNAs that regulate target gene expression Screening for miRNAs that affect a cellular process MicroRNAs (miRNAs) are small, regulatory...Radiation before surgery cuts cancer recurrence
According to a report, giving radiation to surgical treatment for rectal cancer may not make much difference in the survival of patients. But the findings suggest that the radiation treatments given before surgery may help improve the patient's quality of life by reducing the rate of cancer recurrence at or near the original tumor site in the rectum. In about 15% to 45% of patients who...Heparin does not protect from recurrent heart attacks
Professor Mahaffey and his team from Duke Clinical Research Institute have found that either form of heparin (both low molecular weight and unfractionated)gives emergency// protection to heart attack patients by breaking the clots in blood flow to the heart reducing the risk of heart attacks for 24 hours. Though both the forms of heparin gives emergency treatment they are not found to avo...Estrogen Does Not Prevent Recurrent Strokes
Despite some past evidence that hormone replacement might lower stroke risk in older women, new research shows that estrogen therapy does not protect women from recurrent strokes and may instead carry some risks. The findings add to growing evidence that hormone replacement therapy does not have the cardiovascular benefits doctors once believed. // Many doctors have long thought hormo...Radiation reduces cancer recurrence
According to a report, giving radiation to surgical treatment for rectal cancer may not make much difference in the survival of patients. But the findings suggest that the radiation treatments given before surgery //may help improve the patient's quality of life by reducing the rate of cancer recurrence at or near the original tumor site in the rectum. In about 15% to 45% of patients w...Lowering Risk of Breast Cancer Recurrence
A new class of drugs could reduce the risk of breast cancer recurrence in post-menopausal women.Exemestane is a third-generation aromatase inhibitor. Aromatase inhibitors are drugs that block the conversion of precursor molecules. In the case of breast cancer, aromatase inhibitors block the conversion of precursor molecules into various types of estrogenic compounds. //In a new study, coo...Investigational Drug Cediranib (AZD2171) Shows Promise in Patients With Recurrent Glioblastoma (GBM)
Phase II GBM study presented at ASCO with cediranib - a selectiveVEGF signaling inhibitor - shows over a quarter of patients aliveand progression- free at six months(1) CHICAGO, June 04, 2007 /PRNewswire/ -- Data for theinvestigational agent cediranib (AZD2171) were presented today atthe annual meeting of the American Society of Clinical Oncology(ASCO) from a study in patients with recurr...