Recombinant

Analysis of Four Large Post-Marketing Surveillance Studies Describe Clinical Effects of Sucrose-Formulated Recombinant Factor VIII

BOSTON, July 13 /PRNewswire/ -- New data pooled from four large, "real world" post-marketing surveillance studies showed that sucrose-formulated recombinant factor VIII (rFVIII-FS) reduced bleeding and provided data regarding adverse events in more than 950 patients with mild-to-severe hemophilia ...

InVitria Announces Launch of Recombinant Albumin for Diagnostics

InVitria's Recombinant Albumin-DX eliminates safety concerns, stabilizes sensitive biomarkers and enhances diagnostic performance by improving specificity. Fort Collins, CO (PRWEB) April 2, 2009 -- Addressing significant product safety and consistency issues in the huma...

China Medicine Releases White Paper on Developing Recombinant Aflatoxin-Detoxifizyme

GUANGZHOU, China, July 9 /Xinhua-PRNewswire/ -- China Medicine Corporation (OTC Bulletin Board: CHME; " China Medicine" or " the Company"), a leading distributor and developer of ethical and over-the-counter drugs, traditional Chinese Medicine (TCM), nutritional and dietary supplements, medica...

Targeted Genetics Reports on Recombinant DNA Advisory Committee (RAC) Assessment of Its Phase I/II Trial of tgAAC94 for Inflammatory Arthritis

SEATTLE, Dec. 3 /PRNewswire-FirstCall/ -- Targeted Genetics Corporation (Nasdaq: TGEN ) today reported on the National Institutes of Health (NIH) Recombinant DNA Advisory Committee's (RAC) assessment of the previously reported fatal serious adverse event (SAE) in the Phase I/II trial of tgAAC...

FDA Approves New 3000 IU Vial Size for Kogenate(R) FS, antihemophilic factor (recombinant)

... with filter and other materials necessary for safe reconstitution and fast recombinant factor VIII treatment in a small, tamper-evident box with anticounterfeitin...CATIONS Kogenate(R) FS, antihemophilic factor (recombinant) , is a recombinant factor VIII treatment indicated for the control and prevention of bleeding ...

Professor Bruce Beutler Joins aTyr Pharma's Scientific Advisory Board

...ts with inflammatory disease. Dr. Beutler is the inventor of Enbrel(R), the prototype for the most successful class of biotherapeutics ever developed: recombinant inhibitors of TNF that are used to treat inflammatory diseases such as rheumatoid arthritis. aTyr Pharma's discovery candidates for anti-inflam...

Recombinant in Medical Technology

XTL Biopharmaceuticals Announces the Acquisition of the Use Patent on Recombinant Erythropoietin (rHuEPO) for the Treatment of Multiple Myeloma

REHOVOT, Israel, March 18 /PRNewswire-FirstCall/ -- XTL Biopharmaceuticals Ltd. (Nasdaq: XTLB ; TASE: XTL) announced today that it has entered into an asset purchase agreement with Bio-GAL Ltd, a private company, for the rights to a use patent on Recombinant Erythropoietin ("rHuEPO") for the...

Bone Biologics Announces Significant Milestone for Spinal Fusion Surgery Using Recombinant Protein and Demineralized Bone Matrix

Primate trials validate efficacy of the process THOUSAND OAKS, Calif., Feb. 24 /PRNewswire/ -- Bone Biologics, Inc. announced today that it has successfully completed the initial primate trials validating the efficacy of the proprietary bone growth regeneration UCB-1 (NELL-1) protein in spina...

ProFibrix Steps up Recombinant Fibrinogen Program With PER.C6(R) License From Crucell

LEIDEN, The Netherlands, January 13 /PRNewswire/ -- ProFibrix B.V., today announced that it has concluded a commercial license agreement with Crucell N.V. (Euronext, NASDAQ: CRXL ; Swiss Exchange: CRX) for PER.C6(R), a unique human protein production platform. The PER.C6(R) platform allows P...

Halozyme Therapeutics Announces Phase I Clinical Trial Results Demonstrating that the Combination of Recombinant Human Hyaluronidase (rHuPH20) With Humulin R(R) and with Humalog(R) Yields Faster, More Physiologic Insulin Kinetics and Better Predictability

SAN FRANCISCO, June 9 /PRNewswire-FirstCall/ -- Halozyme Therapeutics, Inc. (Nasdaq: HALO ), a biopharmaceutical company developing and commercializing products targeting the extracellular matrix, today announced new Phase I data for the company's diabetes mellitus program at the American Dia...

PharmAthene's Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimer's Disease

ANNAPOLIS, Md., April 9, 2008 /PRNewswire-FirstCall/ -- PharmAthene, Inc. (Amex: PIP ) a biodefense company specializing in the development and commercialization of medical countermeasures against chemical and biological threats, announced today that scientists from the Hebrew University of J...

AlphaMed Pharmaceuticals Announces Breakthrough in the Development of Recombinant Alpha 1-Antitrypsin

LARGO, Fla., March 7 /PRNewswire/ -- AlphaMed Pharmaceuticals Corporation announced today that the Company has successfully expressed a humanized version of the therapeutic protein alpha 1-antitrypsin (AAT). AlphaMed scientists expressed their recombinant AAT utilizing the Company's proprietar...

Recombinant in Medical Products

ImmunoDOT Borrelia (Lyme) Test (with Recombinant Protein)

Description: The ImmunoDOT Borrelia (Lyme) test is an enzyme immunoassay (EIA) dot-blot test for the qualitative detection of borrelia antibodies. Both species specific (anti-P39) and related Borrelia burgdorferi antibodies (IgG, IgM, and IgA) are detected in serum as an aid in the diagnosis of Lyme disease...
Company:GenBio

Epstein-Barr Virus (EBV) VCA IgM Recombinant IFA (RIFA)

Description: Recombinant immunofluorescent antibody ( RIFA:) test for the detection and semi-quantitation of human serum IgM antibodies to Epstein-Barr viral capsid antigen (VCA). Each kit contains ten 12-well slides prepared with recombinant EBV VCA antigen, FITC IgM RIFA: conjugate, positive and negative cont...
Company:Focus Diagnostics

Dynabeads® MyOne™ Streptavidin T1

Description:... 1 m Dynabeads with covalently bound recombinant streptavidin, allowing capture of any biotinylated target. The Dynabeads® MyOne™ have a large surface area, high capacity, magnetic pull and...
Company:Dynal Biotech, LLC

ImmunoWELL Measles (Recombinant) IgG Test

Description:... The ImmunoWELL Measles recombinant IgG Test is an ELISA method for the qualitative detection of IgG to Measles (Rubeola) virus. Test results are used as an aid to determine immune sta...
Company:GenBio

Chagatest ELISA

Description:... With membrane parasite soluble lysate (epimastigote phase) and cytoplasm as antigen. Since this kit employs different antigens than the recombinant kit, it is possible to use two ELISA techniques as screening, ensuring a higher diagnostic sensitivity....
Company:Wiener Lab

Chagatest ELISA recombinante V 3.0

Description:... This new kit uses proteins produced with recombinant technology, that have been fully prove throughout Latin America, and which are capable of detecting the different types of T.cruzi that exist in this ...
Company:Wiener Lab

Recombinant in Medical Dictionary

Tuberculosis

... including its causes, symptoms, and treatment. Tuberculosis is the most common major infectious disease today, infecting two ... The first recombinant tuberculosis vaccine entered clinical trials in the United ... Communicable Disease Fact Sheet, tuberculosis ... " Tuberculosis " is also ...

Total protein

.... Total protein Western blots for proteomics, gene discovery, & protein functional ... Protein Kits. Peptides and Blocking Peptides. recombinant Proteins. Total ... ...

Sepsis

...psis ? ... The pro-inflammatory cytokines TNF and IL-6 are important mediators in sepsis . ... Mortality Due to Severe Sepsis and Septic Shock. recombinant Activated Protein C (rhAPC) ... Palm Sepsis Tool. Improvement Measures from Participating Institutions ... Explains the cause, symptoms, diagnos...

Macrophage

...ish dictionary and ... histiocyte - a macrophage that is found in connective tissue ... eBioscience technical data sheet for product 14-8339 recombinant Human GM-CSF (Granulocyte/ Macrophage -Colony Stimulating Factor, GMCSF) antibody Structure and function of human white blood cells ... They fo...

Growth hormone

...and that stimulates growth and cell reproduction. In the past growth hormone was extracted from human pituitary glands. GH is now produced by recombinant DNA technology and is prescribed for a variety... About the human growth hormone commonly used to treat children of pathologically short statu...

Erythropoietin

...ased, erythropoietin travels to the bone marrow where it binds to a ... recombinant erythropoietin therapy can be highly effective in a number of ... Er... ((EPO) ... Serum erythropoietin ; EPO. How the test is performed ... recombinant erythropoietin is a therapeutic agent produced by DNA technology in ......

Recombinant in Biological News

InVitria Announces Launch of Recombinant Albumin for Diagnostics

Fort Collins, CO, April 17, 2009 / b3c newswire / - Addressing significant product safety and consistency issues in the human diagnostics market, InVitria has announced the commercial launch of two protease-free recombinant albumin products. InVitria’s Recombinant Albumin-DX and Re...

Tailor-made recombinant proteins in mammals

BERKELEY, CA A new way to direct chemical modifications to specific sites on recombinant proteins including the monoclonal antibodies so important in the pharmaceutical industry has been developed by Carolyn Bertozzi and her colleagues at the U.S. Department of Energy's Lawrence Berkeley Nation...

Emergence of recombinant forms of HIV: dynamics and scaling

The emergence of drug resistant forms of HIV often underlies the failure of current antiretroviral therapies for HIV infection. Specific mutations in the HIV genome confer resistance to individual drugs. Recombination, a process similar to sexual reproduction in higher organisms, can accelerate ...

Live Recombinant Adenovirus Vaccine Technique Explored

Researchers at the Johns Hopkins Bloomberg School of Public Health are exploring ways to develop new vaccines for a variety of illnesses using genetically modified adenoviruses, a common cause of respiratory infections. Oral adenovirus vaccines have long been proven to be safe and effective. The re...

GUMC discovery highlights new direction for drug discovery

...sing proteins are disordered. In their 15-year search for a new treatment for Ewing's sarcoma, Toretsky and his colleagues were the first to make a recombinant EWS-FLI1 fusion protein. They used it to discover that the fusion protein stuck to another protein, RNA helicase A (RHA), a molecule that forms protei...

Anti-biotech groups obstruct forest biotechnology

... been in direct opposition to widespread scientific and professional opinion from around the world, including from ecologists, that the trait, not the recombinant method, should be the focus of assessments." Another key part of the problem, the researchers said, is finding enough scientists to participate in ...

Recombinant in Biological Technology

PacificGMP and USC to Collaborate on Recombinant Protein Development and Manufacturing for Phase 1 Clinical Trial

SAN DIEGO and LOS ANGELES, July 27 /PRNewswire/ -- PacificGMP, the leader in single-use bioprocessing for development and manufacturing for its client partners, and the University of Southern California (USC) announced today that they have signed an agreement whereby PacificGMP will prov...

Inspiration Biopharmaceuticals Presents Safety Data on IB1001, a Novel Recombinant Factor IX for the Treatment of Hemophilia at the International Society on Thrombosis and Haemostasis (ISTH) Annual Meeting

LAGUNA NIGUEL, Calif., July 14 /PRNewswire/ -- Inspiration Biopharmaceuticals today announced the presentation of positive preclinical safety, toxicology and preliminary pharmacokinetic data on its lead product, IB1001, a novel recombinant Factor IX product to treat patients with he...

Richter-Helm and Athera Biotechnologies Partner in Development of Recombinant Protein to Treat Cardiovascular Disease

HAMBURG, Germany and STOCKHOLM, January 21 /PRNewswire/ -- Richter-Helm BioLogics GmbH & Co. KG and Athera Biotechnologies AB have signed an agreement for the development and manufacturing of Athera's novel product for prevention of plaque rupture and athero-thrombosis through binding of t...

PharmAthene Response to DHHS Request for Proposals for Recombinant Protective Antigen Anthrax Vaccine Deemed Technically Acceptable and Within Competitive Range for Procurement Consideration

ANNAPOLIS, Md., Sept. 15 /PRNewswire-FirstCall/ -- PharmAthene, Inc. (Amex: PIP ) a biodefense company specializing in the development and commercialization of medical countermeasures against chemical and biological threats, announced today that it has received notification from the Departmen...

New Recombinant XYNTHA Now Available for Patients with Hemophilia A

COLLEGEVILLE, Pa., Sept. 8 /PRNewswire/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), announced today that product shipments have begun for XYNTHA(TM) Antihemophilic Factor (Recombinant), Plasma/Albumin-Free, a new recombinant factor VIII product for both the control and prevent...

Deloitte Agrees to Acquire Recombinant Capital, A Leading Life Sciences Subscription Database and Advisory Services Firm

Transaction reinforces Deloitte's leading position in the life sciences industry NEW YORK, June 16 /PRNewswire/ -- Deloitte has announced today an agreement to acquire Recombinant Capital, Inc. (Recap), a leading life sciences subscription database and advisory s...

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Recombinant in Biological Products

hKvLQT1/hminK-CHO K1 Recombinant Cell Line from Upstate

Description: PrecisION Ion Channel Cell Lines High Quality, Functionally-Validated, Ion Channel Cell Lines Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investiga...
Company:Upstate

hNav1.6-HEK293 Recombinant Cell Line from Upstate

Description: PrecisION Ion Channel Cell Lines High Quality, Functionally-Validated, Ion Channel Cell Lines Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investiga...
Company:Upstate

hKv1.5-CHO K1 Recombinant Cell Line from Upstate

Description: PrecisION Ion Channel Cell Lines High Quality, Functionally-Validated, Ion Channel Cell Lines Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investiga...
Company:Upstate

hHCN4-CHO K1 Recombinant Cell Line from Upstate

Description: PrecisION Ion Channel Cell Lines High Quality, Functionally-Validated, Ion Channel Cell Lines Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investiga...
Company:Upstate

hERG-CHO K1 Recombinant Cell Line from Upstate

Description: PrecisION Ion Channel Cell Lines High Quality, Functionally-Validated, Ion Channel Cell Lines Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investiga...
Company:Upstate

hERG-CHO K1 Recombinant Cell Line from Upstate

Description: PrecisION Ion Channel Cell Lines High Quality, Functionally-Validated, Ion Channel Cell Lines Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investiga...
Company:Upstate

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Recombinant in Biological Definition

Affinity chromatography

...ell free extracts and antibody purification from blood serum . Possibly the most common use of affinity chromatography is for the purification of recombinant proteins. Essentially proteins are tagged with a known affinity ligand in order to aid their purification. That is to say that the molecule has an a...

Bacterium

...e development of a transverse cell wall. However, independent of sexual reproduction, genetic variations can occur within individual cells through recombinant events such as mutation (random genetic change within a cell's own genetic code). Similar to more complex organisms, bacteria also have mechanisms ...

Biotechnology

...e word biotechnology 1975 Method for producing monoclonal antibody developed by Kohler and Milstein 1980 Modern biotech is characterized by recombinant DNA technology . The prokaryote model, E. coli , is used to produce insulin and other medicine, in human form. (About 5% of diabetics are allerg...

Chromatography

...oordinate covalent binding between histidine or other unique amino acids (either naturally present on the surface of the protein or grafted with recombinant DNA techniques ) and various immobilized metal ions, such as copper, nickel, zinc, or iron. Salt concentration is increased to produce later fractio...

Chromosomal crossover

...asis of crossing over was first demonstrated by Harriet Creighton and Barbara McClintock in 1931 . See also Genetic recombination recombinant frequency ...

Bacterium

...e development of a transverse cell wall. However, independent of sexual reproduction, genetic variations can occur within individual cells through recombinant events such as mutation (random genetic change within a cell's own genetic code). Similar to more complex organisms, bacteria also have mechanisms ...

Recombinant in Biological Dictionary

Recombinant

Recombinant DNA is a form of DNA that does not exist naturally, which is created by combining DNA sequences that would not normally occur together. In terms of genetic modification, recombinant DNA (rDNA) is introduced... Recombinant virus - a virus formed by recombining genetic ma...

Transgenic mouse

... organism (GEO) is an organism whose genetic material has been altered using genetic engineering techniques. These techniques, generally known as recombinant DNA... Explanations about transgenic mouse and the history of biological experimentations ... ©2005 transgenicmouse.com - transgenic mice ...

Transgenic animals

... organism (GEO) is an organism whose genetic material has been altered using genetic engineering techniques. These techniques, generally known as recombinant DNA... Transgenic animals , i.e., engineered to carry genes from other species, have the ... Some transgenic animals are produced for speci...

Transgenic

...ing genetic engineering techniques. These techniques, generally known as recombinant DNA... The technology has already produced transgenic animals such ...o becoming useful commercially. ... Biotechnology company that produces recombinant proteins and monoclonal antibodies for pharmaceutical use in the mil...

Structural biology

...th the molecular structure of This NCCR is a network of Swiss research groups working in the field of structural biology . It mainly focuses on recombinant protein technologies, macromolecular ... Structural Biology Laboratory. The Salk Institute for. Biological Studies. P.O. Box 85800 ... Stru...

Streptavidin

...in -plus is stable. as a lyophilizate for at ... The biotin-binding activity of streptavidin is. determined using a modification of the dye ... recombinant streptavidin is immobilized via covalent binding of primary amino ... Streptavidin is a 53,000 dalton tetrameric protein purified from the bac...