Receptor

Activation of thermoreceptors mediates raw garlic's burning pungency

The worldwide popularity of garlic as a food ingredient and its therapeutic stature in folklore both stem in part from the distinctive pungency associated with its raw, uncooked state. Researchers this week report that this pungency, manifested as a characteristic mixture of burning and prickling sensations and flavor, can be ascribed largely to the effects of a particular compound and its abilit...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

The immune system is a marvel of versatility, creating a variety of cells that develop in different ways to protect the body. To carry out these tasks, immune cells follow a career path that forks at various points in their development. In a report in the May 2005 issue of Immunity, Fox Chase Cancer Center scientists led by immunologists David L. Wiest, Ph.D. and Dietmar J. Kappes, Ph.D., show th...

Small worm yields big clue on muscle receptor action

Researchers at the University of Illinois at Chicago have identified an elusive subunit of a neurotransmitter receptor found in both humans and the much-studied laboratory nematode C. elegans which may open new pathways of research on muscle function. The neurotransmitter acetylcholine binds to two different nicotinic receptors at the nematode's neuromuscular junctions, causing them to con...

Evolution of taste receptor may have shaped human sensitivity to toxic compounds

Researchers have found new evidence suggesting that the ability to taste bitter compounds has been strongly advantageous in human evolution. Animals rely on chemical perception, including the senses of taste and smell, for protection against the harmful compounds found in nature. It is widely believed that behavioral and dietary choices may have reduced the importance of such chemical perc...

Missing Receptor Molecule Causes Tumor Growth

A missing receptor molecule contributes to the growth of tumors in human ovaries. This surprisingly evident connection has now been proven by a team at the Medical University of Vienna, who published their data in the science journal Molecular Cancer Research. The team, who is supported by funding from the Austrian Science Fund FWF, also discovered the possible genetic reason why the receptor mol...

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Receptor at Biology Products

PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)

Description:The PolarScreen Androgen Receptor (AR) Competitor Assay Kits provide a sensitive and efficient method for studying and screening potential AR ligands using fluorescence polarization (FP). The kits contain rat AR ligand binding domain protein tagged with His and GST [AR-LBD (His-GST)], and a novel, selective fluorescent androgen ligand (Fluormone AL Green in the green assay kit or Fluormone AL Red...
Company:Molecular Probes (Invitrogen)

PolarScreen Progesterone Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)

Description:PolarScreen Progesterone Receptor (PR) Competitor Assay Kits are ideal for studying or screening novel progesterone receptor binding compounds using fluorescence polarization (FP). The homogenous assay utilizes a fusion of glutathione transferase to the ligand binding domain of human progesterone receptor [PR-LBD(GST)] and a proprietary, fluorescently tagged progesterone ligand, Fluormone PL Gree...
Company:Molecular Probes (Invitrogen)

PolarScreen Glucocorticoid Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)

Description:PolarScreen Glucocorticoid Receptor (GR) Competitor Assay Kits are ideal for studying or screening novel GR binding compounds. The PolarScreen GR Competitor Assay Kits contain partially purified GR protein, stabilizing peptide, buffer, and one of the following proprietary fluorescent glucocorticoid Fluormone ligands: GS1 (green assay kit), GS Red (red assay kit), or GS Far Red (far red assay kit)...
Company:Molecular Probes (Invitrogen)

Rabbit Anti-Neuromedin U Receptor 1 Polyclonal Antibody, Unconjugated from Novus Biologicals

Description:Rabbit polyclonal antibody to Neuromedin U Receptor 1 (GPR66)...
Company:Novus Biologicals

Mouse Anti-Human Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4) Monoclonal Antibody, Unconjugated from Lifespan Biosciences

Description:Mouse Anti-Human Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4 Monoclonal Antibody New...
Company:Lifespan Biosciences

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Receptor at Biology Technology

Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling

Danny Q. Hoang Michael Browning Xinping Yang PeterPingerelli Stratagene Cloning Systems, Inc. Stratagene introduces affinity purified antibodies for NMDA receptorsubunits that are useful for studying expression of the NR2A, NR2B and NR2Csubunit proteins...

Detecting Gastrin-Releasing Peptide Receptor by in situ PCR on Archived Tissue

In situ Adapter for the RoboCycler 40 Temperature Cycler allows rapidamplification of rare mRNA Department of Medicine, University of Illinois at Chicago Figure 1: RoboCycler 40 Temperature Cycler In Situ Adapter Syst...

pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins

Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...

Gene-Specific Primers for NMDA Receptor Subunits

Robert Buchner Peter L. Pingerelli Michael D. Browning Mary Ellen Simcox Stratagene Cloning Systems, Inc. Stratagene is now offering gene-specific primer sets for the rat and humanNMDA receptor. In this article, we describe using these primers in reversetran...

TKB1 Cells Identify Receptor Tyrosine Kinase Interacting Proteins

Institute for Molecular Biology and Biotechnology, McMaster University,Ontario, Canada GST-fusion proteins expressed in TKB1 bacteria are used to affinity purifycellular proteins, which interact with a specific autophosphorylation site onthe Erb...

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Receptor at Biology Definition

Transmembrane receptor

of some subcellular compartments and <a href="/ ?q=/ Biology-Defin...

Receptor

may refer to: . is any structure which, on receiving environmental stimu...

Receptor at Biology Dictionary

Transmembrane receptor

of...

Transferrin receptor

surfaces. Regulation of TfR is important to the regulation of iron uptake and <a hr...

Receptor

<A href="http:/ / en.wikipedia.org/ wik...

Chemoreceptors

pigmen...

Receptor at Medicine News

Soluble IL-4 Receptor - A new boon for asthmatics

Bronchial asthma, the disease which is never an easy combat for any practising physician, is now being avenged by a new drug. A soluble interleukin-4 receptor (IL-4R), which acts as an IL-4 antagonist, appears to be safe and effective in preventing a decline in lung function and in preventing asthma symptoms. In their study, Dr. Larry C. Borish, from the University of Virginia Health Sci...

Angiotensin-II-receptor blockers - Treat kidney failure

Drugs used to treat high blood pressure have been found to also help slow the progress of kidney failure. Three separate drug trials reveal that the angiotensin-II-receptor blockers, which include losartan and irbesartan, can be used to treat kidney failure, one of the commonest complications in diabetes. // In the first trial, carried out by doctors in Boston, USA, 1500 patients...

Comprehension of taste receptor

American scientists, have recognised an amino-acid taste receptor.Dr Charles S. Zuker, from the Howard Hughes Medical Institute and the University of California, San Diego, reports his team's findings in a recent journal.Humans can identify five different tastes — bitter, salty, sour, sweet, and umami. Umami is the flavour associated with monosodium glutamate (MSG).Receptors that responded t...

Calcium Receptor Vital For Stem Cell Migration to Bone Marrow

A new discovery of a dictator molecule that governs the migration of blood stem cells to the bone marrow, resulting in subsequent production of blood cell components and immune stem cells could // hold the key to the development of more effective stem cell therapy for malignant and non-malignant conditions in the future. "This is another remarkable example of how bone and bone marrow...

Treatment for cholesterol-related illnesses likely with the discovery of receptor in mice

Researchers have reported in the February issue of PNAS that understanding and treating cholesterol-related illnesses in humans may now be easier with the discovery of a receptor in the cells of mice that protects them from toxins. Researchers discovered the receptor during a study of cerebrotendinous xanthomatosis (CTX), a rare and often fatal disorder caused by excessive cholesterol metabolites...

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Receptor at Medicine Products

TSH Receptor (TSHR) Autoantibody Coated-Tube (CT)

Description:Coated-Tube (CT) RIA kit for the determination of autoantibodies to the TSH receptor (TSHR) in serum...
Company:KRONUS

TSH Receptor (TSHR) Autoantibody - ELISA

Description:ELISA kit for the determination of autoantibodies to the TSH receptor (TSHR) in serum....
Company:KRONUS

TSH Receptor (TSHR) Autoantibody - RIA

Description:RIA kit for the determination of autoantibodies to the TSH receptor (TSHR) in serum [with calibrators]....
Company:KRONUS

Acetylcholine Receptor (AChR) Binding Autoantibody RIA

Description:RIA kit for the determination of binding autoantibodies to the acetylcholine receptor (AChR) in serum....
Company:KRONUS

Acetylcholine Receptor (AChR) Blocking Autoantibody RIA

Description:RIA kit for the determination of blocking autoantibodies to the acetylcholine receptor (AChR) in serum...
Company:KRONUS

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Receptor at Medicine Technology

YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds to the EGF Receptor and Potentiates Radiotherapy

MISSISSAUGA, ON, July 09, 2007 /PRNewswire-FirstCall/ - YMBioSciences Inc. , an oncology company that identifies, developsand commercializes differentiated products for patients worldwide,today announced that a study presented by investigators from KinkiUniversity School of Medicine and Kyoto University at the 11thmeeting of The Japanese Association for Molecular Target Therapy ofCancer...

Human Genome Sciences Reports Growing Evidence That Its TRAIL Receptor Antibodies Have Significant Potential in the Treatment of a Broad Range of Cancers

- Journal of Clinical Oncology publishes first clinical study ofHGS-ETR1 - ROCKVILLE, Md., April 27, 2007 /PRNewswire-FirstCall/ -- HumanGenome Sciences, Inc. today reported that clinical and preclinicalevidence continues to emerge demonstrating that its TRAIL receptorantibodies, HGS-ETR1 (mapatumumab) and HGS-ETR2 (lexatumumab), havesignificant potential for use in the treatment of a bro...

First Controlled Large-Scale Intervention Angiotensin Receptor Blocker (ARB) Trial in a Japanese Population, JIKEI HEART Study Demonstrates Significant Reduction in Blood Pressure and Protection of Organs with Valsartan

Unprecedented Evidence for the Effectiveness of HypertensionTreatment Valsartan in Preventing Cardiovascular Events in JapanesePatients TOKYO, April 26, 2007 /Xinhua-PRNewswire/ -- The clinicaloutcomes of the JIKEI HEART Study, the large-scale clinical trialheaded by the Jikei University School of Medicine, was todaypublished in the internationally renowned medical journal TheLancet. The...

Positive Results Using Affitech-Identified Human Antibody That Blocks VEGF Binding to VEGF Receptor 2 in Preclinical Cancer Model Reported by Peregrine

OSLO, Norway--(BUSINESS WIRE)--Apr 23, 2007 - Affitech AS, thehuman antibody therapeutics company announced today that PeregrinePharmaceuticals, Inc. reported positive in vivo test results of R3,a fully human monoclonal antibody developed by Affitech, in apancreatic cancer model at the recently concluded Centennial AnnualMeeting of the American Association for Cancer Research (AACR). R3has...

Portola Pharmaceuticals Presents Positive Phase I Data of Its ADP Receptor Antagonist at the American College of Cardiology

NEW ORLEANS, March 28, 2007 /PRNewswire/ -- PortolaPharmaceuticals, Inc. presented Phase I data of its ADP receptorantagonist at the of Cardiology's (ACC) 56th Annual ScientificSession this week. Portola's reversible antiplatelet compound,PRT060128, appeared safe and well-tolerated in this study andachieved high-level platelet inhibition. Portola presented the data in a poster sess...

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