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Reactivated in Medical News

Newly Reactivated Health Economics Research Institute to Launch New Initiatives for Improving Health Care Delivery

NORTHBROOK, Ill., Jan. 7 /PRNewswire-USNewswire/ -- With national health care reform a top priority of the 2008 Election debates, and with a plethora of reform proposals swirling about Washington, D.C., and around the country, the newly revamped Health Economics Research Institute (HERI) is steppi...

Australian team reveals world-first discovery in a 'floppy baby' syndrome

...he body, but by birth, heart actin has almost completely disappeared within skeletal muscle. Using genetic techniques, the WAIMR research team has reactivated the heart actin after birth in place of skeletal muscle actin, reversing the effects of the congenital myopathy. Head of the WAIMR research group...

Scientists identify gene in breast cancer pathway

... Biophotonics Center at Einstein. He is one of ZBP1's discoverers and leader of the current study. Researchers have subsequently found that ZBP1 is reactivated in several types of cancer, including breast, colorectal, and non-small cell lung cancers; but the gene is silenced in metastasizing cancer cells, as ...

Cancer stem cells generated by cancer outgrowth

...outgrowth of cells in the animal. "To our knowledge, this is the first example that silenced endogenous embryonic stem cell genes can be spontaneously reactivated in differentiated cells," says Dr. Dean. "We propose that the loss of cell contact inhibition when the RB1 pathway is inhibited leads to outgrowth int...

Master molecular switch may prevent the spread of cancer cells to distant sites in the body

...the epithelial to mesenchymal transition, or EMT, and is an important process during the development of embryos. But when the transition is aberrantly reactivated in adults it can have dire physiological consequences, leading to cancer metastasis as well as other disease processes such as tissue fibrosis. Fibrot...

IMPACT Study Demonstrates That Longer Prophylactic Therapy With Valcyte(R) (Valganciclovir Hydrochloride Tablets) Increases Protection Against CMV - the Most Serious Viral Infection Affecting Transplant Patients

...at 50-80% of all adults have been infected with the CMV virus. In the majority of cases the virus lies dormant in the body throughout life, but can be reactivated at times when the immune system is weakened (e.g., transplant patients, AIDS patients and premature infants). CMV is the most important serious infect...

Childhood brain tumor traced to normal stem cells gone bad

... -- can be transformed into tumors. The transformation occurs when a cell-signaling pathway known as Sonic hedgehog (named for a cartoon character) is reactivated by a chance mutation. Sonic hedgehog plays an important role during the embryonic development of the brain, but normally shuts down when it's no lo...

'HiCy' drug regimen reverses ms symptoms in selected patients

...err. Kerr cautions that the "reboot" phenomenon didn't work in all the patients. Two years after treatment, MRI images showed that the disease had reactivated in about half the study participants, suggesting that their renewed ability may not be permanent. Kerr's colleague Adam Kaplin, M.D., Ph.D., assist...

Targeting aggressive breast cancers by putting them to sleep

... It is well established that Id1, a gene normally produced only in embryonic development, is reactivated in many 'solid' cancers, or carcinomas. In the case of breast cancer, the Id1 gene is active only in the more aggressive and metastatic varieties o...

JCI online early table of contents: Feb. 7, 2008

...penditure. The molecule D3 can inactivate thyroid hormones; however, D3 is typically found in only a few postnatal tissues, although its expression is reactivated in the liver and skeletal muscle of critically ill patients. In a new study, Stephen Huang and his colleagues at the Harvard Institutes of Medicine, B...
Reactivated in Medical Technology

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

...t 50-80% of all adults have been infected with the CMV virus. In the majority of cases the virus lies dormant in the body throughout life, but can be reactivated at times when the immune system is weakened (e.g., transplant patients and AIDS patients). CMV is the most important serious infection complicating s...

Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)

...y Vidaza. The epigenetic approach to cancer therapy is that rather than using molecules that kill both normal, and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natural mechanisms to control abnormal growth. About MDS Myelodysplastic sy...

Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)

...y Vidaza. The epigenetic approach to cancer therapy is that rather than using molecules that kill both normal, and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natural mechanisms to control abnormal growth. About MDS Myelodysplastic synd...

Clinical Data Reported on Vidaza in Hematologic Malignancies and Advanced Solid Tumors

...ing molecules that kill both normal and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natu...ing molecules that kill both normal and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natu...
Reactivated in Biological News

Potential new HIV drug may help patients not responding to treatment

...hinery that makes IDO and use it to stop the immune system from attacking them. In the new study, the researchers could find no evidence that D-1mT reactivated the immune response against SIV, although they do not exclude this possibility. They are now keen to carry out further research to explore how D-1mT i...

An end to fear

...e on seeing the spider, unlike the control group who had been administered a placebo. The group that had received propranolol but whose memory was not reactivated still exhibited a strong startle response. The fear response was measured using two electrodes under the eye that measured the eye-blinking reflex. Th...

January-February GSA Bulletin media highlights

...hat the generally linear chasmata of Valles Marineris reflect extension, collapse, and excavation along fractures radial to Tharsis, either forming or reactivated as part of one lateral margin of the Thaumasia gravity-spreading system. The other, dextral, lateral margin is a massive splay of extensional faults f...

CMV infections affect more than just patients with compromised immune systems, researchers find

...immunity ICU patients can help cut down on reactivation of CMV, or whether it can cut down on the length of hospital stays for those patients with the reactivated virus. "There are side effects associated with the treatment for CMV, and CMV might simply be a marker, rather than a cause," Limaye explained. "B...

UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes

...ted" from distinct sites in the cell to the telomere, an area at the end of a chromosome that normally protects it from destruction. "Telomerase is reactivated in more than 90 percent of human cancers," said Michael Terns, professor of biochemistry and molecular biology and genetics at UGA, "and the fact that...

Turning a cellular sentinel into a cancer killer

...r Gregory Hannon at Cold Spring Harbor Laboratory. When the researchers reactivated p53 in the mice they found that the liver tumors completely disappeared. "T...at the drug tamoxifen could be used to switch on p53 activity. "When we reactivated p53 in these mice, we saw two distinct tumor phenotypes," said Jacks. "In l...

Infected for life

...ual cannot detect the infected cell. Latent HSV-1 infections form in neuronal cells of the peripheral nervous system. When a latent infection is reactivated (by stress of many kinds), HSV-1 proteins are synthesized and new infectious virus particles are formed. These virus particles migrate along the neuro...

Restoring silenced suppressor gene kills lung-cancer cells

...gene can slow or stop the cells' growth. The study also showed that the reactivated gene is highly effective in stopping the growth of human lung tumors that h...cer Center . "This suggests that if this gene could be delivered to, or reactivated in, the tumor cells of lung-cancer cases that are deficient in this gene, i...

NYU biologists map out early stages of embryo formation

...stand how human embryos develop, and may also provide new insights for cancer research since genes acting in early embryogenesis are often erroneously reactivated in cancer cells. The research is the latest in a series of studies conducted at NYU's Center for Comparative Functional Genomics in collaboration w...

Sleeping beauty plays a significant role in identifying cancer genes

...ther study, University of Minnesota researchers took defunct, non-functioning jumping genes from fish and made the genes jump again. This research had reactivated the jumping genes from millions of years of evolutionary sleep; hence the name Sleeping Beauty. In the two current research studies, specially desi...
Reactivated in Biological Technology

Indevus Announces Management Changes

...ew retirement date to be determined by mutual agreement between Dr. Cooper and the Board. The search for a new CEO has been placed on hold and will be reactivated at the appropriate time. Given the delay of NEBIDO, the Company has begun a thorough review of its operating expenses and its R & D programs with th...

EMEA Accepts for Review Vidaza(R) Marketing Authorization Application for Higher-Risk Myelodysplastic Syndromes

...by Vidaza. The epigenetic approach to cancer therapy is that rather than using molecules that kill both normal and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natural mechanisms to control abnormal growth. About MDS Myelodysplastic sy...

Scientists synthesize memory in yeast cells

...ch it had originated, reactivating it. This caused the gene to once again create that very same transcription factor, which once again looped back and reactivated the gene. In other words, the second gene continually switched itself on via the very transcription factor it created when it was switched on. ...

Scientists synthesize memory in yeast cells

...ch it had originated, reactivating it. This caused the gene to once again create that very same transcription factor, which once again looped back and reactivated the gene. In other words, the second gene continually switched itself on via the very transcription factor it created when it was switched on. ...

Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes

...ctivation. The epigenetic approach to cancer therapy is that rather than using molecules that kill both normal and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natural mechanisms to control abnormal growth. About Pharmion Pharmion is a l...
Reactivated in Biological Definition

Lambda phage

... or destroy the host. At that point, the prophage becomes active again, excises itself from the DNA of the host cell and enters its lytic cycle . The reactivated phage takes apart the host's DNA and "reprograms" its "protein factory" to produce new phages in multiple copies. When all resources of the host are d...
Reactivated in Biological Dictionary

Hemoglobin

...al and international news enhanced with audio and video clips and photo galleries - updated 24/7... In adults, fetal hemoglobin production can be reactivated pharmacologically, ... blood cells, this substance decreases the affinity of hemoglobin for oxygen. ... The myoglobin and hemoglobin page pro...
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