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Rats in Medical News

Stroke Damage Is Less in Rats Given Opioids

Drugs induce a state of hibernation that improves recovery, study shows WEDNESDAY, June 17 (HealthDay News) -- Hibernation induced by opioid drugs reduced brain damage and behavioral dysfunction in a study of rats that experienced an experimental stroke, researchers report. "Studies...

Scientists find city rats are loyal to their 'hoods

In the rat race of life, one thing is certain: there's no place like home. Now, a study just released in Molecular Ecology finds the same is true for rats. Although inner city rodents appear to roam freely, most form distinct neighborhoods where they spend the majority of their lives. Like an...

Team Regrows Neurons Controlling Movement in Rats

Goal is to one day develop a therapy to help with spinal cord injuries MONDAY, April 6 (HealthDay News) -- Using genetically engineered cells and a virus as a delivery method, researchers were able to regenerate a type of nerve fiber in rat brains that controls movement. This isn't ...

Mutant rats offer clues to medical mystery

HOUSTON (Feb. 17, 2009) A research project at Rice University has brought scientists to the brink of comprehending a long-standing medical mystery that may link cardiovascular disease, osteoporosis and perhaps even Alzheimer's disease. And for that, we can thank the rat. The recent paper i...

Bound by attention: Bringing rats and humans together

When picking through a basket of fruit, it doesn't seem very difficult to recognize a green pear from a green apple. This is easy, thanks to "feature binding" a process by which our brain combines all of the specific features of an object and gives us a complete and unified picture of it. For exam...

A good ear: Rats identify specific sounds in noisy environments

A study conducted on hundreds of rats could help us understand how the brain identifies specific sounds in a noisy environment. The investigation, soon to be published in the journal Brain, was conducted by Alex Martin of the Universit de Montral Department of Psychology. "Our ears have thousan...

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Rats in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

MILWAUKEE, RICHMOND, Calif., ST LOUIS, PALO ALTO, Calif., and PARIS, July 23 /PRNewswire-FirstCall/ -- Scientists from The Medical College of Wisconsin in Milwaukee, Sangamo Biosciences, Inc., (Nasdaq: SGMO ), Sigma-Aldrich Corporation (Nasdaq: SIAL ), Open Monoclonal Technology...

Neuralstem's Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS

Make Synaptic Contact with Host Motor Neurons ROCKVILLE, Md., March 9 /PRNewswire-FirstCall/ -- Transplanted human neural stem cells (hNSCs) developed by Neuralstem, Inc. (NYSE Alternext US: CUR) made synaptic contacts with the motor neurons of rats with ALS-like symptoms, a paper published i...

Stanford Researchers Find Brain Pathway of Depression in Rats

STANFORD, Calif.--(BUSINESS WIRE)--Jul 5, 2007 - Scientists' hunt for the cause of depression has implicated so many suspects and found so many treatments with different mechanisms that the condition remains an enigma. Now researchers at the Stanford University School of Medicine have identified on...

New Study Shows that Prebiotics, as Used by Jackson GI Medical, Increases Lifespan by 33%

... The controlled clinical study was conducted on rats and showed that the rats fed prebiotics had an 80% survival rate to 24 mont...s versus a 50% survival rate for the control group rats that were not fed prebiotics. Additionally, the "p...

Dendreon Presents Preclinical Data Demonstrating Activity of TRPM8 Agonist, D-3263, in Benign Prostatic Hyperplasia

...30 a.m. to 12:30 p.m. CDT. In a preclinical study, BPH was induced in rats through subcutaneous injection of testosterone propionate (TP). One week a...llected and weighed, and tissue sections were examined histologically. rats with TP-induced BPH who were treated with D-3263, finasteride or a combinat...

ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients

...icology studies of ANA598, of 26 weeks duration in rats and 39 weeks duration in monkeys. Based on a now ...d Adverse Effect Level (NOAEL) in monkeys and male rats remains 1000 mg/kg at 13 weeks, the highest dose being tested in the chronic studies. In female rats the NOAEL at the 13-week interim was 300 mg/kg, wi...
Rats in Medical Definition

Episodic memory

... addition, studies by Eacott and colleagues (Eacott et al, 2005) have shown rats can recall (remember without any cueing influences) what they saw and where...t-Teke, E., De Souza Silva, M.A., Huston, J.P. & Dere, E.(2006). Wistar rats show episodic-like memory for unique experiences. Neurobiology of Learning ...
Rats in Medical Dictionary

Protein C

... world's first wiki where authorship really matters. Due credit and ... Activated protein C reduces stress-induced gastric mucosal injury in rats by ... Compare Cheap Prices for Protein C at NexTag.com. Find Great Bargains on Sporting Goods, Toys, Collectibles, Car Parts, Food, and the G...

Olfactory

...y ... Approximately 2 million Americans experience some type of olfactory dysfunction. ... Progression of alachlor-induced olfactory tumors in rats is accompanied by ... No olfactory mucosal tumors were observed in any of the mice, although alachlor ... ... in human olfactory perception, i...

Fructose

...nd discuss your questions with fructose experts. Consuming too much fructose will encourage weight gain, and not just because ... However, the rats on the high- fructose diet had higher levels of triglycerides ... University of Texas Southwestern Medical Center ... Fructose , on the other ...

Ethylene glycol

... ... STATUS OF DATA FOR Ethylene glycol . File First On-Line 09/30/1987 ... Chronic toxicity and oncogenicity studies of ethylene glycol in rats and mice. Fund. ... Ethylene glycol (EG) is the dihydroxy alcohol derivative of ethane.It was ... Ethylene glycol's major toxicities are a...

Aflatoxin

...pes of mold: ... There are several aflatoxin strains, with B1 the most common and most toxic. ... For example, with pure aflatoxin B1, all the rats developed cancer by week 88 at ... Researchers at the Delta Research Center demonstrate and research agricultural ... Aflatoxin is a term gene...
Rats in Biological News

City rats loyal to their 'hoods, scientists discover

In the rat race of life, one thing is certain: there's no place like home. Now, a study published this week in the journal Molecular Ecology finds the same is as true for rats as for humans. Although inner city rodents appear to roam freely, most form distinct neighborhoods where they spe...

Stem cells replace stroke-damaged tissue in rats

Effective stem cell treatment for strokes has taken a significant step forward today (09 March) as scientists reveal how they have replaced stroke-damaged brain tissue in rats. The team of scientists is funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and led by Dr M...

4 days of REM sleep deprivation contributes to a reduction of cell proliferation in rats

WESTCHESTER, Ill. Four days exposure to a REM sleep deprivation procedure reduces cell proliferation in the part of the forebrain that contributes to long-term memory of rats, according to a study published in the February 1 issue of the journal SLEEP. The study, authored by Dennis McGinty, Ph...

Glucose triggers brain cell death in rats after hypoglycemic coma

Brain damage that was thought to be caused by hypoglycemic coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center. The results are surprising, say the authors, and may be of clinical significa...

Metacognition: Faced with a test, rats can check their knowledge first

Researchers have found evidence that rats are capable of metacognition—that is, they can possess knowledge of their own cognitive states. This ability, which can also be thought of as the capacity to assess or reflect on one's own mental processes, was previously only recognized in humans and other...

Human stem cell treatment restores motor function in paralyzed rats

Rats paralyzed due to loss of blood flow to the spine returned to near normal ambulatory function six weeks after receiving grafts of human spinal stem cells (hSSCs), researchers from the University of California, San Diego (UCSD) School of Medicine report. The study, led by Martin Marsala, M.D., ...

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Rats in Biological Technology

USC researchers derive first embryonic stem cells from rats

Researchers at the University of Southern California (USC) have, for the first time in history, derived authentic embryonic stem (ES) cells from rats. This breakthrough finding will enable scientists to create far more effective animal models for the study of a range of human diseases. The res...

Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats

Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats Precise and cost-effective micronucleus analysis made easy with the icroFlow Micronucleus Analysis Kit Dorothea K. Torous Carol R. Tometsko Litron Laboratories, Rochester, N...

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

...essful completion of six-month and nine-month chronic toxicology studies in rats and monkeys, respectively which clear the way for our Phase 2 and Phase 3 c...gy studies in two specific species: a six-month chronic toxicology study in rats and a nine-month chronic toxicology study in monkeys. There were no signif...

Transposagen Creates a Rat Model of the Human Immune System

...immune system. Transposagen will be marketing SCID rats to pharmaceutical and biotechnology companies. "Tr...very and development research. Transposagen's SCID rats are characterized by a deficiency of T-cells, B-ce...fying enzymes are very similar to those in humans. rats are also better models than mice for specific dise...

Anadys Pharmaceuticals Receives FDA Clearance of Phase II Protocol to Study ANA598 in Combination With Interferon-Alpha and Ribavirin in HCV Patients

...toxicology studies of ANA598 (26 weeks duration in rats and 39 weeks duration in monkeys). At the 13-week...ssessment of the results from the 26-week study in rats indicates a similar profile to that seen in rats at 13 weeks, in which the only adverse finding was...

Anadys Pharmaceuticals Reports Second Quarter 2009 Financial Results and Program Highlights

...toxicology studies of ANA598 (26 weeks duration in rats and 39 weeks duration in monkeys). At the 13-week...ssessment of the results from the 26-week study in rats indicates a similar profile to that seen in rats at 13 weeks, in which the only adverse finding was...
Rats in Biological Products

Rotarod Treadmill one unit for mice and rats from IITC Life Science

Description: The IITC Life Science Rotarods are used to assess the effect of drugs on the motor coordination or fatigue resistance on mice and rats using one unit in a safe and humane way. Extremely user friendly; the animals are placed on textured drums to avoid slipping. When an animal drops onto the individu...
Company:IITC Life Science

Corticosterone EIA Kit from IDS Ltd

Description:...EIA) for the quantitative determination of corticosterone in mouse or rat serum or plasma. Corticosterone is the major, if not sole, corticosteroid in rats and mice, and in most non-mammalian vertebrates such as amphibia, birds and reptiles. Most mammals produce both corticosterone and cortisol, in varyin...
Company:IDS Ltd

Rabbit Anti-Human CELSR3 Polyclonal Antibody, Unconjugated from GeneTex

Description:...s an Orphan-U GPCR with an unknown ligand. In mouse, this gene is expressed during development at sites of active neurogenesis and in adult mice and rats in brain, spinal cord, dorsal root ganglion, and eye. ESTs have been isolated from human B-cell/lung/testis, blood, brain, colon, heart/melanocyte/ute...
Company:GeneTex
Rats in Biological Definition

Albumin

...bumin in the urine. In nephrotic syndrome, this property is lost, and there is more albumin loss in the urine. Because smaller animals (for example rats ) function at a lower blood pressure , they need less oncotic pressure to balance this, and thus need less albumin to maintain proper fluid distribut...

Ebola

...ural reservoir is a carrier of the virus that is immune to its effects. Although many of the creatures — ranging from spiders to insects to rats and bats — found in the factory were tested for Ebola, none of the tests came back testing positive (Draper 30-31). The natural reservoir for...

Foot and mouth disease

... viral disease of cattle and pigs . It can also infect deer , goats , sheep , and other animals with cloven hooves, as well as elephants , rats , and hedgehogs . Horses are not susceptible to FMD. Humans are affected only very rarely. The cause of FMD was first shown to be viral in 1897...

Limbic system

...s located in the limbic system. It is involved in sexual arousal and in the "high" derived from certain recreational drugs . Dopamine acts here. rats with electrodes implanted into their limbic system will self-stimulate in preference over food and will eventually die of exhaustion. The limbic sy...

Long-term potentiation

...hen subjected to the Morris water maze , in which rats were placed into a pool of murky water and tested ...e a platform hidden beneath the water's surface. rats in the control group were able to locate the platf... from the pool, whereas the ability of APV-treated rats to complete the task was significantly impaired. M...

Sociobiology

...y , 1960 ) that argued that " racism " actually exists in most mammalian species, because racial groups within mammalian species (such as moose , rats , and reindeer ) tend to compete for space and fight rather than mate and form offspring. Hence, "racism" could have an instinctive component in hum...
Rats in Biological Dictionary

Spermatids

...psy material or ... Round spermatids were collected from the testicles of rats of both groups, the ... ( t) Newly formed Sa spermatids of stage I hav...ll as a centrally ... ... spermatids was observed in the testes from rats in which ... Key words: Pachytene spermatids , round spermatids , develop...

Seminiferous tubules

...niferous tubules . ... Seminiferous tubules . Seminific. Seminification. seminin ... Structural alterations in the seminiferous tubules of rats treated with ... Seminiferous tubules cross sections were randomly chosen in three non-serial ... Locate the seminiferous tubules and the r...

Schwann cells

... proliferate, migrate along axons, ensheath individual axons, and ... Primary Schwann cells were prepared from sciatic nerves of Sprague–Dawley rats ... The development of Schwann cells , the my ... axons and myelinating Schwann cells attain the one-to-one ... that Schwann cells isola...

Polysome

...x ... mRNA polysome association. ... We also examined the polysome distribution of the 5′-6bs ... Hepatic polysome profiles vary in untreated rats as a function of time of day. ... Regulation of polysome aggregation in a cell-free system through amino acid supply. ... Polysome preparatio...

Pachytene

... and P450 aromatase in pachytene spermatocytes suggests a role for estrogens ... a well-known model of pachytene spermatocyte apoptosis in adult rats ... After elutriation, pachytene spermatocytes were cultured in minimal essential ... ( B) Pachytene spermatocytes were pretreated with selecti...

Homeothermic

...omputer Desktop Encyclopedia, computing dictionary. Homeothermic heating systems have a thermal probe to monitor the animals temperature, ... rats and larger animals, for use with Homeothermic System controller... Words similar to homeothermic : homeotherm, homeothermy, homoiothermic, homot...
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