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Rationale in Medical News

On March 4, 2009, The United States Supreme Court Rejected the Rationale Behind Michigan's Drug Product Liability Law

DETROIT, March 4 /PRNewswire/ -- On March 4, 2009, the United States Supreme Court in the case of Wyeth v. Levine , rejected the drug company's argument that because it was complying with FDA standards it should be immune from suit. Because of this decision, citizens in all states except Michi...

New Research Suggests Most Are Willing to Make Tradeoffs and Would Embrace Comprehensive Health Care Reform

...d on to the public, they were more likely to see the practical and economic rationale for extending coverage to all Americans. Americans are open to rev...d on to the public, they were more likely to see the practical and economic rationale for extending coverage to all Americans. Language is a critical, th...

Hard to Treat Diseases, Inc. (HTDS) Reports on Ribavirin Research as Potential Treatment for MS

...odel of multiple sclerosis) by limiting cytokine-mediated immuno-inflammatory events that lead to CNS destruction. The conducted experiments provide rationale for ribavirin to be considered as a candidate drug in the development of new therapeutic strategies for the treatment of autoimmune diseases in humans...

In New York City, Trans Fat Ban Is Working

...port that Tiburon, a small community north of San Francisco, actually restricted trans fats in its 18 restaurants as early as 2003. "The scientific rationale for eliminating exposure to artificial trans fatty acids in foods is rock solid," she wrote. Not only do they not have health benefits, but they are h...

NeurogesX Announces Resignation of Bruce A. Peacock from Board of Directors

... initial regulatory approval and E.U. partnership discussions surrounding Qutenza. We are disappointed in his resignation but certainly understand the rationale and wish him well in his future endeavors." Following Mr. Peacock's departure NeurogesX has received a Nasdaq Staff Deficiency Letter dated J...

CNCB Post Graduate Studies in Clinical Nutrition (PGSCN) Program is Now Available Online

...dality - Herbology Clinical Nutrition Counseling with Alternative Therapies Session IV - Laboratory Assessment rationale for Laboratory Assessment Vitamins - the Working Hands of Enzymes Minerals & Laboratory Testing Amino Acids & Laboratory ...

Moderate Drinking Might Guard Against Alzheimer's

...l. And it has been thought that this could potentially impact in a positive way on the risk for vascular dementia and Alzheimer's. So there is a solid rationale for this finding." The Alzheimer's-cardiovascular health connection are, in fact, the subject of another study also being presented at the meeting....

Mayo Clinic study using structural MRI may help accurately diagnose dementia patients

...ework, which is called "STructural Abnormality iNDex" or STAND-Map, shows promise in accurately diagnosing dementia patients while they are alive. The rationale is that if each neurodegenerative disorder can be associated with a unique pattern of atrophy specific on MRI, then it may be possible to differential...

Mayo Clinic Study Using Structural MRI May Help Accurately Diagnose Dementia Patients

...ework, which is called "STructural Abnormality iNDex" or STAND-Map, shows promise in accurately diagnosing dementia patients while they are alive. The rationale is that if each neurodegenerative disorder can be associated with a unique pattern of atrophy specific on MRI, then it may be possible to differential...

International conference on reproductive science to be held in Pittsburgh July 18-22

... intimidating, said SSR president Asgerally T. Fazleabas, Ph.D., of the University of Illinois College of Medicine in Chicago. But, he noted, the same rationale also says that a healthy life must begin in the womb. "Learning as much as we can about this critical time in development, and the influences upon ...
Rationale in Medical Technology

Neurobiological Technologies, Inc. Presents Dosing Rationale for Viprinex(TM) (ancrod) at the European Stroke Conference

NICE, France, May 14 /PRNewswire-FirstCall/ -- Neurobiological Technologies, Inc. (NTI(R)) (Nasdaq: NTII ) reported for the first time at the European Stroke Conference detailed analyses supporting the dosing regimen in NTI's two ongoing Phase 3 studies of Viprinex(TM) (ancrod) for ischemic s...

Current Status of the Development Programs of New Indications and Formulations for Aricept(R) for Enhancing Patient Value

...on (FDA) in August or September 2009. 2. Pediatric Use Eisai filed a Proposed Pediatric Study Request (PPSR), an application that proposes a rationale and study design for pediatric studies, with the U.S. FDA in February 2009 to evaluate the clinical benefits of donepezil in children with attention i...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

...ans to file an Investigational New Drug Application for PR-957 in mid-2010. "The research published today in Nature Medicine provides a strong rationale for clinical development of PR-957 in rheumatoid arthritis and other inflammatory and autoimmune diseases," said John A. Scarlett, M.D., President and...

Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial

...va, MD, Executive Vice President, Global Head, Novartis Oncology Development. "These latest data show an antitumor effect in lymphoma that support the rationale for a Phase III study of Afinitor to prevent relapse in patients with diffuse large B-cell lymphoma, where there is a significant unmet medical need."...

Bayer Announces New Data on Novel Anti-cancer Compound BAY 73-4506

...06," said lead investigator Professor Tim Eisen, F.R.C.P., PhD, of Addenbrooke's Hospital at the University of Cambridge , UK. "These data provide a rationale to move into a Phase III trial in one of the multiple tumor types that may be responsive to BAY 73-4506." Additional data presented on BAY 73-45...

Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

...dy participants to obtain overall survival data, and expect those data later this year. The new PFS, tumor response and neurotoxicity data provide the rationale to consider additional trials to develop picoplatin as a preferred platinum for the treatment of metastatic colorectal cancer." Analyst and Inve...

Theranostics Health Announces Involvement with Major Academic Medical Center in Study Funded by Susan G. Komen for the Cure(R)

...established in May 2008. Studies conducted by Theranostics Health with Dr. Victoria Seewaldt, MD, a Duke investigator, have provided the underlying rationale and preliminary data in support of the research proposed for the Promise Grant. Dr. Seewaldt is dedicated to discovering and developing new preventio...

BioVex to Report Phase I/II Clinical Trial Results for the Front Line Treatment of Head and Neck Cancer With OncoVEX GM-CSF at the 2009 American Society of Clinical Oncology Meeting

..., 2009 from 2:00pm - 6:00pm EDT on Level 2, West Hall F3 of the conference. A poster discussion will take place from 5:00pm - 6:00pm EDT. Study rationale Patients with head and neck cancer often present with bulky disease that is too large or too close to vital organs for surgical removal. These ...

CMC ICOS Biologics and Implicit Bioscience Ltd Announce IC14 Antibody Manufacturing Agreement and Patent License

...ed safety profile in over 150 patient exposures, and initial data from a pilot clinical trial in mechanically-ventilated patients has provided a clear rationale for clinical development in ALI. CMC ICOS is a company dedicated to contract development and manufacturing for the biotechnology sector. The com...

Autism Studies Presented at Mid-Atlantic Research Consortium Meeting

...awing on diverse populations of patients, finding a broader pool of information than even a large facility can provide. Such collaboration is the rationale for the Mid-Atlantic Research Consortium (MAC) of the federally sponsored Intellectual and Developmental Disabilities Research Centers (IDDRC). The co...
Rationale in Medical Products

EyeDoc

Description:...nd treatment plan. It has rich graphics capabilities where one can draw his/her findings as desired. It follows the patients progress and provides the rationale for ordering ancillary tests....
Company:Penn Medical Informatics Systems, Inc.
Rationale in Medical Definition

Allopathic medicine

...s of illness. In the essay by William Jarvis cited below, he notes that "although many modern therapies can be construed to conform to an allopathic rationale (eg, using a laxative to relieve constipation), standard medicine has never paid allegiance to an allopathic principle" and that the label "allopath" ...
Rationale in Medical Dictionary

In situ

...ontaminant concentra ... Advantages of in situ flushing include: ... Evaluations Of In - Situ Groundwater Bioremediation System Design X-24. rationale For The Design. ... Schematic Diagram Of Typical In - Situ Groundwater ... EBS offers premier soil and groundwater remediation, site / in - sit...

Hyperglycemia

... Chronic hyperglycemia causes damage to the eyes, kidneys, nerves, heart and blood vessels. ... The adverse impact of hyperglycemia and the rationale for ... ...

Cobalamin

...to treat pernicious anemia ... Vitamin B12 is is a water-soluble vitamin needed for normal nerve cell activity, DNA replication, ... The rationale for using high-dose cobalamin (vitamin B12) ... ... for families of children affected by inborn errors of cobalamin metabolism. ... The Cob...
Rationale in Biological News

Vaccine blocks malaria transmission in lab experiments

...lative ease of expression and induction of potent transmission-blocking antibodies in mice and non-human primates. This approach provides a compelling rationale and basis for testing a transmission-blocking vaccine in humans," said Nirbhay Kumar, PhD, senior author of the study and professor in Johns Hopkins B...

Free online toolkit provides standard measures for genome and population studies

...in 24 hours , and nicotine dependence. In addition to measures under each category, the toolkit includes information about each measure such as the rationale for its selection, standard data collection protocols, and a summary of research personnel and required training. Other categories of measures such as...

A miR boost enables acute leukemia cells to mature

...s them. The study is reported online in the journal Blood . "We show that miR-29b is a powerful demethylating agent and provides a rationale for developing this molecule as a possible drug for the treatment of AML, alone or in combination with other agents," says first author Dr. Ramiro Gar...

Cellulosic biofuel technology will generate low-cost green fuel, says major study

...Lynd et al, which outlines the RBAEF project and provides an operative definition of, and method for estimating, mature technology. It also looks at a rationale for choosing the model feedstock, a list of the conversion technologies considered and, as a point of reference, a brief overview of the energy flows ...

Airborne asthma allergens

...r the observed high asthma prevalence. "This work revealed the presence of fungal allergens that can be potential asthma triggers and establishes a rationale for future research in this area," the researchers conclude. ...

Common food additive found to increase risk and speed spread of lung cancer

...er in man. "We know that only some patients who smoke develop lung cancer but the reasons for this varying risk are unknown. This study now provides a rationale for funding case-control studies in humans to determine the potential role of dietary phosphates in promoting cancer." ...

IRB Barcelona to coordinate two European projects on biomedicine

...e transmission of malaria, with the aim to identify the key components that inhibit this process and allow the development of anti-malarial drugs. The rationale behind Ribas de Pouplana's project is that "we now have enough knowledge about protein synthesis in organisms such as the bacteria E.coli or the yeast...

Artificial Gravity receives 2008 Life Science Book Award

...he award will be presented at the Academy Day Honor Night on 28 September 2008 in Glasgow, Scotland. Artificial Gravity reviews the principle and rationale for using artificial gravity during space missions, and describes the current options proposed, including a short-radius centrifuge contained within a...

Video released of rapid Alzheimer's improvement after new immune-based treatment

...ck, "There are limitations to the data presented; the clinical trial was open label, and not controlled. These caveats notwithstanding, the scientific rationale for the further investigation of anti-TNF-alpha treatment of Alzheimer's disease is compelling. In addition, family members, independent neurologists,...

2 new therapies show promise for cancer patients

... test safety, hoping it will also determine efficacy. The fact that we saw this kind of activity in a phase I trial is dramatic, Von Hoff said. The rationale behind the combination of Gemcitabine plus Abraxane was based on careful science and was designed and executed by some of the leading experts in pancr...
Rationale in Biological Technology

Northwest Biotherapeutics Announces Plans to De-list From AIM and Consolidate its Stock Market Listing in U.S.

...all of the Company' shareholders in advance of this meeting. One of the purposes of the meeting and the circular and proxy materials is to explain the rationale behind the proposed de-listing and consolidation of trading in the Company's shares on a single market in the U.S. Shareholders will be asked to vote...

NeoStem Featured on CBS2 News; Success of Licensed Stem Cell Treatments Shown for Arthritis and Orthopedic Problems; Procedure to be Used by NeoStem Affiliate in China

...ies that is a key element of NeoStem's growth strategy in both the United States and China." As stated in the Form 8-K of July 10, 2009: "The rationale behind NeoStem's expansion in China is to accelerate stem cell therapy, research and development and creation of intellectual property position in an ...

Lytix Biopharma and KAEL-GemVax Announce Joint Clinical Trial to Combine LTX-315 and GV1001 Cancer Immunotherapy

... anti-cancer vaccines currently in development, with a potentially broad utility against a range of cancer types. "There is a strong scientific rationale for combining these agents, providing a local inflammatory response combined with specific vaccination - these two novel agents should have the potent...

PharmAthene Presents Data for SparVax(TM), a Novel Vaccine for the Prevention and Treatment of Anthrax Infection, at the 12th Annual Conference on Vaccine Research

...ioThrax(R), with good immunologic memory demonstrated after antigen exposure at 6 or 12 months. "This is an important finding and supports the rationale for stockpiling a highly purified second generation anthrax vaccine utilizing modern vaccine technology as described in the March 2002 Institute of Me...

Access Pharmaceuticals Presents New Data on ProLindac(TM) at the 2009 AACR Annual Meeting

...uld provide sustained tumor exposure to platinum and provides a mechanistic rationale for the low hematoxicity observed in the clinic - DALLAS, April 21 /PR...on the binding of ProLindac to blood components, and suggests a mechanistic rationale for ProLindac's favorable efficacy and safety profile. "The data shows...

ImQuest Presentation at Keystone Symposium Focuses on Advancements in Their Cancer Research and Development Program

...hese results highlight the significant potential of the piperazines as highly potent and broadly active chemotherapeutic agents and provide additional rationale for their expedited development," said Dr. Robert W. Buckheit Executive Vice President and Chief Scientific Officer, and presentation co-author. ...

Polycystic Kidney Disease Assay at Cornell University Uses Transgenomic's Surveyor Nuclease & WAVE Technology

...identify presence of mutations limits the amount of DNA sequencing required, since it is only necessary for confirmation of identified mutations. This rationale provides a logical and cost-effective improvement to the workflow for analyzing large genes such as PKD1 and PKD2 , which Hanna Rennert's team demo...

GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2008 Financial Results

...in New York City. Dr. McNally presented a corporate overview of GeoVax and its DNA/MVA vaccine technology, showcasing the scientific rationale and encouraging data from the Company's completed studies and trials. GeoVax's presentation was offered via a live webcast. A replay...

Agendia Presents Data Supporting MammaPrint's Predictive and Prognostic Power at 2009 St. Gallen Breast Cancer Conference

...e shown that chemotherapy particularly reduces early metastasis risk. In planning treatment, the MammaPrint test result provides a doctor with a clear rationale to assess the benefit of chemotherapy in addition to other clinical information and pathology tests. All MammaPrint tests are conducted in Agen...

Agendia Publishes Direct Evidence That MammaPrint Predicts Benefit of Chemotherapy in Breast Cancer

...e shown that chemotherapy particularly reduces early metastasis risk. In planning treatment, the MammaPrint test result provides a doctor with a clear rationale to assess the benefit of chemotherapy in addition to other clinical information and pathology tests. All MammaPrint tests are conducted in Agen...
Rationale in Biological Definition

Human

...a central trait of human nature, and "animal with sapience" (ζωον λογον εχων, animal rationale ), a term that also inspired the species' taxonomy, Homo sapiens . From a scientific viewpoint, Homo sapiens certainly is among the most generali...
Rationale in Biological Dictionary

N-terminus

...avage ... C-terminus or N-terminus of the target ... This suggests that the H2B N-terminus might play an inhibitory role in chromatin ... The rationale for targeting the H2B N-terminus was twofold. ... ... Human IL-21 N-terminus . DATASHEET. Specificity: Peptide sequence ... Above: Immunocytoc...

Muscle contraction

...drome - tetany ... ... are the contractile units of the muscle and are organized into sarcomeres. ... This scene illustrates the sliding filament rationale for muscle contraction . ... A muscle contraction (also known as a muscle twitch or simply twitch) occurs ... Voluntary muscle contract...
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