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Ratiometric in Medical News

Frederick R. Appelbaum, M.D. and Ross C. Donehower, M.D. Join Scientific Advisory Board of Celator(R) Pharmaceuticals

...(TM), the company's technology platform, represents a revolutionary new approach to the development of combination therapies based on the principle of ratiometric dosing, where drug agents are combined and maintained in the optimal ratio to target cancer cells with maximum effectiveness. The company pipeline inc...
Ratiometric in Medical Technology

Celator Pharmaceuticals Study Shows Anti-Tumor Activity in Cancer Patients Treated with Therapy Based on Ratiometric Dosing

Phase I results for CPX-1 presented at ASCO confirm safety findings and demonstrate clinical benefit in more than 70% of patients with colorectal and other types of cancer. PRINCETON, N.J., June 04, 2007 /PRNewswire/ -- Celator Pharmaceuticals announced positive safety and efficacy results from it...
Ratiometric in Medical Products

FlexStation II and FlexStation II384

Features:... scanning fluorometer Provides both top- or bottom-read functions with the click of a mouse Dual monochromator design offers the ability to perform ratiometric and multiplex applications Integrated 8- or 16-channel pipettor Transfer compounds from one microplate to the assay plate, allows prompt kinetic a...
Company:Bucher Biotec AG
Ratiometric in Biological News

Magnet Lab researchers make observing cell functions easier

...ly been able to monitor one biosensor at a time. The new technique, called Dual FRET, is outlined in the paper Fluorescent Protein FRET Pairs for ratiometric Imaging of Dual Biosensors. http://www.nature.com/nmeth/journal/v5/n5/abs/nmeth.1207.html Further expanding the capabilities of optical microscop...
Ratiometric in Biological Technology

Monitoring Receptor-Mediated Changes in [Ca2+]i Using Single-Wavelength and Dual-Wavelength Indicators on the FlexStation Workstation

... FlexStation Calcium Assay Kit) or dual-wavelength ratiometric indicators, such as Fura-2. With single-wavelength...ty is dependent on the Ca 2+ concentration whilst ratiometric indicators undergo a spectral shift that is propor... (permitting the use of lower dye concentrations), ratiometric dyes offer several advantages over conventional si...

FLIPR Calcium 3 Assay Kit - An Optimal No-Wash Fluorescence Calcium Indicator Reagent for Non-Optimal Calcium Responses

...ium by virtue of changes in their fluorescence signal upon calcium binding. FURA-2 exhibits a spectral shift following calcium binding and is used for ratiometric measurement of calcium concentration with dual wavelength UV excitation and single wavelength emission. On the other hand the visible light-excitable...
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