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Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

For the first time, scientists have foundthat bacteria can use a Sonar-like system to spot other cells (eithernormal body cells or other bacteria) and target them for destruction.Reported in the December 24 issue of Science, this finding explains howsome bacteria know when to produce a toxin that makes infection moresevere. It may lead to the design of new toxin inhibitors. “Blocking orinte...

Scientists collaborate to assess health of global environment

For the first time, a group of scientists has accomplished the daunting task of evaluating the status of all of the ecosystems on Earth, and the outlook is troubling. Commissioned by the United Nations in 2001, the Millennium Ecosystem Assessment program will issue its primary report on March 30 during press conferences in London, Washington, D.C., Tokyo, Beijing, New Delhi, Brasilia, Cai...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

The genes TEL2 and MYC cooperate with each other to promote pediatric cases of the immune system cancer B-cell lymphoma. This finding, from investigators at St. Jude Children's Research Hospital, is published in the current issue of Molecular Cell Biology (MCB). B-cell lymphoma is a cancer in which the antibody-producing cells (B lymphocytes) multiply uncontrollably and crowd out other blo...

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Standard Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences

Description:Microarrays designed for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research built on the flexible and powerful Paraflo microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive Protein Kinase Substrate - Peptide Microarray Service. Our standard content PKS...
Company:LC Sciences

Protein Kinase Substrate (PKS) Peptide Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays synthesized on Paraflo microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research. This comprehensive service includes preparation of your kinase sample, single or dual color enzymati...
Company:LC Sciences

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. One mL stains 100 minigels. A 500 µL unit size (S-7564) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. 500 µL stains 50 minigels. A 1 mL unit size (S-7568) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO**special packaging* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. A 500 µL unit size (S-7564) and 1mL unit size (S-7568) are available....
Company:Molecular Probes (Invitrogen)

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New Kit Generates Exceptionally Pure Total RNA for RT-PCR

RT-PCR miniprep kit Stratagene Stratagene has determined that standard RNA purification kits are not satisfactory for reverse transcribed PCR (RT-PCR) applications. We...

Generate Adenovirus Vectors in E. coli by Homologous Recombination with the AdEasy Adenoviral Vector System

Efficient gene transfer and high-level protein expression within a varietyof cells Stratagene Recombinant adenoviruses provide a versatile means of gene delivery andexpression. We describe the AdEasy adenoviral vectorsystem, whichsimp...

Using XL1-Red Mutator Strain to Generate Esterase Variants

XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...

Fractionating DNA Fragments Generated by Differential Display PCR

Pfizer Central Research, Sandwich, UK. 01304 618482 Differential display PCR (DDPCR) is a widely used technique foridentifying genes differentially expressed between cell types. Application ofDDPCR to allergic disease provides a potential means for elucidating themechanisms involved in allergic...

Generate High-Quality, Directional Plasmid cDNA Libraries

Produce larger primary libraries with new plasmid library constructionkits Quinn Lu Marie Callahan Tanya Hosfield BarryNeiditch Alan Greener John C. Bauer Mike Kobrin Stratagene II,pcmv-script and pAD-GAL4-2.1 XR library construction kit...

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Carbohydrate

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Vertebrates

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More Accurate "PROSTATE CANCER" Test can save Unnecessary Biopsies

Prostate cancer can effect men over the age of 40 years and is the second commonest cancer among men after lung cancer. Usually it goes undetected till it is advanced and beyond cure. However a lot of awareness has been created about this condition and now men over the age of 40 years can be screened regularly to detect the cancer. One of the most promising "tumour markers" in medicine...

Doctors operate upon patients in candlelight- latest from the quake scene

The latest word from Gujarat is that doctors are being stretched to their limits working on cases for hours together without a break. At times they work in candlelight when the power fails, but the work goes on. Many caesarean sections to deliver babies were conducted in open verandahs. On Jan 27th nearly 1500 patients were operated upon without a break. Many fractures were fixed without...

Radioactive Seeds used in Prostate Cancer treatment can migrate with the body

In a shocking disclosure, Dr. Murali Ankem, a resident in Urology at the Robert Wood Johnnson Medical Centre of the University of New Jersey Medical and Dental School, New Brunswick, has said that radiactive seeds used in prostate cancer treatment can migrate to other parts of the body including the lungs. In a procedure called Brachytherapy, tiny metal pellets are implanted in and aroun...

Pharma cos must forge Strategic alliances

Indian pharmaceutical majors should go in for strategic alliances among themselves to capture export markets increasingly by leveraging cost advantages and precluding cut-throat competition which would be detrimental to the industry. This was stated by the Commerce Secretary, Mr. Prabir Sengupta, at the opening the Regional Office of the Basic Chemicals, Pharmaceuticals and Cosmetics Exp...

Moderate Use of Analgesics - Not Associated With Kidney Dysfunction

According to a new study, occasional use of aspirin, acetaminophen, or other pain relievers for everyday aches and pains is not associated with kidney dysfunction among healthy men. As analgesic use is so common, even small increases in the relative risk of renal dysfunction could have a significant impact on rates of renal disease. Some earlier studies have suggested that regul...

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Gas operated stool without castors

Description:A sturdy, robust stool. Gas operated height adjustment for convenience....
Company:Haag-Streit UK

Gas operated stool with castors

Description:A sturdy, robust stool. Gas operated height adjustment for convenience....
Company:Haag-Streit UK

L'Anthony's Desaturated 15 Hue Test

Description:The L'Anthony 15 disc test (P/N LD15C) include a durable laminated score template for copying, and comprehensive instructions. P/N LD15C also includes a Plexiglas Case and a supply of finger tip covers for the test subjects fingers ( to maintain cleanliness and accuracy of the color discs). Beware that these finger cots are made with latex....
Company:Richmond Products, Inc.

Magnetic LAnthony 15 desaturated Kit (4 lbs)

Description:Magnets move the color disks, Protects Disks from fingerprints, Keeps all the disks in one place, Clear glass insures accurate color perception, Makes Color testing fun....
Company:Richmond Products, Inc.

Agarwal Karate Phaco Chopper

Description:Karate phaco chopper, semi-sharp, wedge shaped inferior edge with a pointed tip...
Company:Katena Products, Inc.

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Fast, Accurate Influenza A/B Antigen Detection

According to CDC data, influenza infections in this country cause more than 114,000 hospitalizations and 36,000 deaths annually. Among healthy adults, bronchitis and pneumonia are the most common complications. Together, influenza and pneumonia are the sixth leading cause of death in the United States. Influenza is particularly dangerous in elderly and immunocompromised people; however, infec...

GTC Biotherapeutics to Webcast Corporate Presentation at the C.E. Unterberg, Towbin Emerging Growth Life Opportunities Conference

FRAMINGHAM, Mass.--(BUSINESS WIRE)--Jul 5, 2007 - GTCBiotherapeutics, Inc. ("GTC", Nasdaq: GTCB) announced today thatGeoffrey Cox, Ph.D., GTC's Chairman and CEO, is scheduled topresent on Wednesday, July 11, 2007 at 9:00 a.m. during the C.E.Unterberg, Towbin Emerging Growth Life Opportunities Conference.The conference is being held at the Mandarin Oriental Hotel, NewYork, New York from July...

Study Shows Ixabepilone Demonstrated Clear Activity in Patients with Metastatic Breast Cancer Resistant to Anthracycline, Taxane, and Capecitabine

- Phase II Results Published in the Journal of Clinical Oncology - NEW YORK, July 06, 2007 /PRNewswire-FirstCall/ -- Results from aPhase II study - which will be published in the August 10, 2007issue of the Journal of Clinical Oncology (JCO) and are nowavailable as an Early Release Article at <a target="_blank" href="http://www.jco.org/">www.jco.org - demonstrate thatixabepilone, a Br...

Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival

- New Data from Phase III Intergroupe Francophone du Myelome (IFM)Trial Presented During IMW - CAMBRIDGE, Mass., July 02, 2007 /PRNewswire-FirstCall/ --Millennium Pharmaceuticals, Inc. today reported that new data werepresented on the comparative Phase III clinical trial evaluating aVELCADE based therapy in newly diagnosed multiple myeloma (MM)patients. As induction therapy prior to stem...

The International Myeloma Foundation Says Data Reported at a Global Medical Meeting in Greece Demonstrates Improved Survival for a Wide Range of Myeloma Patients

- Data Presented at the 11th International Myeloma Workshop - NORTH HOLLYWOOD, Calif., and KOS, Greece, June 29, 2007/PRNewswire/ -- The International Myeloma Foundation (IMF) --supporting research and providing education, advocacy and supportfor myeloma patients, families, researchers and physicians -- todaysaid that updated statistics reported at the 11th InternationalMyeloma Workshop i...

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Cryostasis (clathrate hydrates)

is a practice of cryo...

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Slow heart rate

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