Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
For the first time, scientists have foundthat bacteria can use a Sonar-like system to spot other cells (eithernormal body cells or other bacteria) and target them for destruction.Reported in the December 24 issue of Science, this finding explains howsome bacteria know when to produce a toxin that makes infection moresevere. It may lead to the design of new toxin inhibitors. “Blocking orinte...Scientists collaborate to assess health of global environment
For the first time, a group of scientists has accomplished the daunting task of evaluating the status of all of the ecosystems on Earth, and the outlook is troubling. Commissioned by the United Nations in 2001, the Millennium Ecosystem Assessment program will issue its primary report on March 30 during press conferences in London, Washington, D.C., Tokyo, Beijing, New Delhi, Brasilia, Cai...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
The genes TEL2 and MYC cooperate with each other to promote pediatric cases of the immune system cancer B-cell lymphoma. This finding, from investigators at St. Jude Children's Research Hospital, is published in the current issue of Molecular Cell Biology (MCB). B-cell lymphoma is a cancer in which the antibody-producing cells (B lymphocytes) multiply uncontrollably and crowd out other blo...Standard Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences
Description:Microarrays designed for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research built on the flexible and powerful Paraflo microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive Protein Kinase Substrate - Peptide Microarray Service. Our standard content PKS...Protein Kinase Substrate (PKS) Peptide Microarray - Comprehensive Service from LC Sciences
Description:LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays synthesized on Paraflo microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research. This comprehensive service includes preparation of your kinase sample, single or dual color enzymati...SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)
Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. One mL stains 100 minigels. A 500 µL unit size (S-7564) and a special packaging (S-7586) are available....SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)
Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. 500 µL stains 50 minigels. A 1 mL unit size (S-7568) and a special packaging (S-7586) are available....New Kit Generates Exceptionally Pure Total RNA for RT-PCR
RT-PCR miniprep kit Stratagene Stratagene has determined that standard RNA purification kits are not satisfactory for reverse transcribed PCR (RT-PCR) applications. We...Using XL1-Red Mutator Strain to Generate Esterase Variants
XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...Fractionating DNA Fragments Generated by Differential Display PCR
Pfizer Central Research, Sandwich, UK. 01304 618482 Differential display PCR (DDPCR) is a widely used technique foridentifying genes differentially expressed between cell types. Application ofDDPCR to allergic disease provides a potential means for elucidating themechanisms involved in allergic...Generate High-Quality, Directional Plasmid cDNA Libraries
Produce larger primary libraries with new plasmid library constructionkits Quinn Lu Marie Callahan Tanya Hosfield BarryNeiditch Alan Greener John C. Bauer Mike Kobrin Stratagene II,pcmv-script and pAD-GAL4-2.1 XR library construction kit...More Accurate "PROSTATE CANCER" Test can save Unnecessary Biopsies
Prostate cancer can effect men over the age of 40 years and is the second commonest cancer among men after lung cancer. Usually it goes undetected till it is advanced and beyond cure. However a lot of awareness has been created about this condition and now men over the age of 40 years can be screened regularly to detect the cancer. One of the most promising "tumour markers" in medicine...Doctors operate upon patients in candlelight- latest from the quake scene
The latest word from Gujarat is that doctors are being stretched to their limits working on cases for hours together without a break. At times they work in candlelight when the power fails, but the work goes on. Many caesarean sections to deliver babies were conducted in open verandahs. On Jan 27th nearly 1500 patients were operated upon without a break. Many fractures were fixed without...Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
In a shocking disclosure, Dr. Murali Ankem, a resident in Urology at the Robert Wood Johnnson Medical Centre of the University of New Jersey Medical and Dental School, New Brunswick, has said that radiactive seeds used in prostate cancer treatment can migrate to other parts of the body including the lungs. In a procedure called Brachytherapy, tiny metal pellets are implanted in and aroun...Pharma cos must forge Strategic alliances
Indian pharmaceutical majors should go in for strategic alliances among themselves to capture export markets increasingly by leveraging cost advantages and precluding cut-throat competition which would be detrimental to the industry. This was stated by the Commerce Secretary, Mr. Prabir Sengupta, at the opening the Regional Office of the Basic Chemicals, Pharmaceuticals and Cosmetics Exp...Moderate Use of Analgesics - Not Associated With Kidney Dysfunction
According to a new study, occasional use of aspirin, acetaminophen, or other pain relievers for everyday aches and pains is not associated with kidney dysfunction among healthy men. As analgesic use is so common, even small increases in the relative risk of renal dysfunction could have a significant impact on rates of renal disease. Some earlier studies have suggested that regul...Gas operated stool without castors
Description:A sturdy, robust stool. Gas operated height adjustment for convenience....Gas operated stool with castors
Description:A sturdy, robust stool. Gas operated height adjustment for convenience....L'Anthony's Desaturated 15 Hue Test
Description:The L'Anthony 15 disc test (P/N LD15C) include a durable laminated score template for copying, and comprehensive instructions. P/N LD15C also includes a Plexiglas Case and a supply of finger tip covers for the test subjects fingers ( to maintain cleanliness and accuracy of the color discs). Beware that these finger cots are made with latex....Magnetic LAnthony 15 desaturated Kit (4 lbs)
Description:Magnets move the color disks, Protects Disks from fingerprints, Keeps all the disks in one place, Clear glass insures accurate color perception, Makes Color testing fun....Fast, Accurate Influenza A/B Antigen Detection
According to CDC data, influenza infections in this country cause more than 114,000 hospitalizations and 36,000 deaths annually. Among healthy adults, bronchitis and pneumonia are the most common complications. Together, influenza and pneumonia are the sixth leading cause of death in the United States. Influenza is particularly dangerous in elderly and immunocompromised people; however, infec...Cryostasis (clathrate hydrates)
is a practice of cryo...