Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Termites feed through good vibrations
Discovery that termites use vibrations to choose the wood they eat may provide opportunities to new methods of reducing infestations in homes and also may provide insights into the "cocktail party effect" of signal processing ?how to ignore most noise but have some signals that trigger attention ?that may prove useful in artificial intelligence. CSIRO entomologist Theo Evans says laborato...Scientists Replicate Hepatitis C Virus in Laboratory
For the first time, scientists have replicated hepatitis C virus (HCV) in the laboratory. The ability to replicate HCV in cell culture will allow researchers to better study the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV. Scientists at the National Institute of Diabetes...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...GATA: a graphic alignment tool for comparative sequence analysis
Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...Full-Configuration Camera Link NI PCIe-1429 from National Instruments Corporation
Description:The National Instruments PCIe-1429 is the industrys first PCI Express image acquisition board.With the NI PCIe-1429, you now can acquire images at the highest speeds, resolutions, and bit depths available for Camera Link cameras to perform demanding imaging applications such as synchronized data and image acquisition, fault analysis, and advanced motion tracking. In the past, acquiring ima...MCP1-S Pipette Calibration Workstation from Mettler Toledo, Inc.
Description:Unique, compact measuring instrument for calibrating single-channel and multi-channel pipettes. Thanks to its compact design and the robust carrying case, the MCP1-S is ideal for calibrating pipettes both in the laboratory and on-site at the users premises. The unit is extremely easy to use because the individual channels are tested automatically. Multi-channel pipettes can therefore be calib...Standard Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences
Description:Microarrays designed for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research built on the flexible and powerful Paraflo microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive Protein Kinase Substrate - Peptide Microarray Service. Our standard content PKS...Rapid-Screen Arrayed cDNA Library Panels Master Plates -Rat Brain (adult) from OriGene Technologies
Description:The Rapid-Screen cDNA Library Panels were designed for full-length gene cloning and require just three sets of PCRs to identify the desired cDNA clone. The first PCR analysis is performed in a 96-well "Master Plate," where each well contains plasmid DNA from 5,000 clones. Having identified the positive well(s) by gel electrophoresis of the reaction products, the second PCR analysis is carried out...Protein Kinase Substrate (PKS) Peptide Microarray - Comprehensive Service from LC Sciences
Description:LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays synthesized on Paraflo microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research. This comprehensive service includes preparation of your kinase sample, single or dual color enzymati...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...New Kit Generates Exceptionally Pure Total RNA for RT-PCR
RT-PCR miniprep kit Stratagene Stratagene has determined that standard RNA purification kits are not satisfactory for reverse transcribed PCR (RT-PCR) applications. We...Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results
Michelle Cayouette Jane Moores Jason Capodanno Michael Rahilly Stratagene produces consistent PCR results in every well. The RoboCycler systems uniquedesign uses thermal blo...New Temperature Cycler Features Interchangeable Blocks
Michelle Cayouette Jane Moores Jason Capodanno Michael Steege Michael Rahilly Stratagene Infinitytemperature cycler, a new temperature cycler withinterchangeable blocks for...Blood Cells Capable of Regenerating Liver
Livers can be regenerated using stem cells from blood -- an important discovery that means patients may be able to grow their own liver transplants using bone marrow. This adds to a growing body of evidence that stem cells, known as "master cells" because they can produce a variety of different kinds of cells, might one day be manipulated to create custom-grown organ transplants....Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
Measurement of serum progesterone levels may be helpful in deciding which emergency department patients with no strong clinical signs are at low risk of ectopic pregnancy, according to a report in the August issue of the Annals of Emergency Medicine. They measured progesterone levels in 716 first-trimester patients who presented to an emergency department with abdominal pain or...Homeopathic preparation better than placebo in perennial allergic
A homeopathic preparation for perennial allergic rhinitis appears to be more effective than placebo. A multicenter team studied 50 patients with perennial allergic rhinitis. The subjects were randomized to receive either 30cc of a homeopathic preparation of principal inhalent allergen or placebo. In the third and fourth week after the start of treatment, the group compared changes in nasa...Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery
A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical...More Accurate "PROSTATE CANCER" Test can save Unnecessary Biopsies
Prostate cancer can effect men over the age of 40 years and is the second commonest cancer among men after lung cancer. Usually it goes undetected till it is advanced and beyond cure. However a lot of awareness has been created about this condition and now men over the age of 40 years can be screened regularly to detect the cancer. One of the most promising "tumour markers" in medicine...Lindstrom Eye Speculum - Aspirating
Description:This adjustable lid speculum is angled 45 degrees and has 17 mm wire blades. It was designed to aspirate excess fluid around the eye during cataract and refractive procedures....Kratz-Barraquer Eye Speculum - Pediatric
Description:Open 10 mm blades. Dull finish....Fast, Accurate Influenza A/B Antigen Detection
According to CDC data, influenza infections in this country cause more than 114,000 hospitalizations and 36,000 deaths annually. Among healthy adults, bronchitis and pneumonia are the most common complications. Together, influenza and pneumonia are the sixth leading cause of death in the United States. Influenza is particularly dangerous in elderly and immunocompromised people; however, infec...Lab Automation Networks Proliferating
Although it may still seem radically innovative in the context of many clinical laboratories, automated production in the manufacturing sector had been the norm for many years. In automobile assembly, for example, automated lines fabricate sub-assemblies and entire vehicles with only occasional human oversight. The result has been vastly improved products, far fewer defects, and significant p...New Quality Control Systems for Every Laboratory Application
Quality Control (QC) materials and procedures are key to meeting the needs of doctors and patients by verifying accuracy and precision of analytical methods. Vendors of these systems can be a valuable resource, designing customized QC materials and protocols to help lab managers ensure that analytical error st...Immunoassay Systems - Your Laboratory Workhorse
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...Cryostasis (clathrate hydrates)
is a practice of cryo...