New method identifies rat poison in humans

Researchers at the Norwegian Institute of Public Health (NIPH) have developed a method to identify bromadiolone poisoning in humans. Bromadiolone is a rat poison that can be purchased freely in shops. A number of cases have been reported internationally where people have been poisoned, with a mort...

Globetrotting black rat genes reveal spread of humans and diseases

DNA of the common Black Rat (Rattus rattus) has shed light on the ancient spread of rats, people and diseases around the globe. Studying the mitochondrial DNA of 165 Black Rat specimens from 32 countries around the world, an international team of scientists has identified six distinct lineages ...

A new soldier in the war on cancer: The blind mole rat

If someone ever calls you a "dirty rat," consider it a compliment. A new discovery published online in the FASEB Journal ( http://www.fasebj.org ) shows that cellular mechanisms used by the blind mole rat to survive the very low oxygen environment of its subterranean niche are the same as those ...

Human Stem Cell Transplants Repair Rat Spinal Cords

Human nerve stem cells transplanted into rats’ damaged spinal cords have survived, grown and in some cases connected// with the rats’ own spinal cord cells in a Johns Hopkins laboratory, overturning the long-held notion that spinal cords won’t allow nerve repair. A report on the experiments w...

Explosion Of Rat Population Poses Health Threat In UK

The rat population has shown a 39 % increase since 1999 leaving the UK health department worried.// Fortnightly garbage collections, compulsory recycling policy and composting bins are said to be the cause of the increasing brown rat population. John Davison of the National Pest Technic...

Developing gene therapy to fight blindness

... The research team's next step is to show that such gene therapy is safe in further animal studies, to be conducted in China, along with additional rat studies that will be conducted at UC San Diego and at the University of Florida. Once safety for the procedure has been shown, the team hopes to p...

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rat in Medical Technology

Stem Cell Sciences Announces the Creation of the World's First Authentic Rat Embryonic Stem Cells from its Exclusively Licensed Technology

CAMBRIDGE, England, September 2 /PRNewswire-FirstCall/ -- - ("Stem Cell Sciences", "SCS", "the Company") Stem Cell Sciences plc (AIM:STEM, ASX:STC), a company focused on the commercialisation of stem cells and stem cell technologies, is pleased to announce that two independent laboratories...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...s in species other than mice. "Until now, rat geneticists lacked a viable technique for 'knockin...knock out an inserted reporter gene and two native rat genes without causing measurable effects on other ...used Sangamo's ZFNs to knock out the gene encoding rat immunoglobulin M (IgM), an important gene for...

New Bisphenol A Study Is of Very Limited Relevance to Human Health

...rolina State University (NCSU) and the National Institute of Environmental Health Sciences (NIEHS). The study, "Neonatal bisphenol A exposure alters rat reproductive development and ovarian morphology without impairing activation of gonadotropin releasing hormone neurons," was funded by NIEHS and publi...

Getting More From Whole-Transcript Microarrays

...xhibit a distinct pattern. However, we believe it could be useful in a variety of experimental settings." FIRMAGene can be applied to human, mouse and rat samples, for which the latest Affymetrix Gene 1.0 ST platforms are available, or any other whole-transcript microarray design. The Walter and Eli...

Myelin Removal Beads: Premium Efficiency for Neural Cell Separations and Antibody Stainings

...rity and recovery of target cells." The novel product is suited for myelin removal from single-cell suspensions obtained from human, mouse, and rat tissues and is especially recommended prior to cell separations and cell stainings with Anti-Prominin-1 , CD133, Anti-PSA-NCAM, Anti-A2B5, or CD11b (m...

Neuralstem's Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS

... human neurons synapsing, or making mature structural connections, with the rat motor neurons, something which has not been demonstrated before," said Dr. ...le. Now we have clear evidence that they can become an integral part of the rat nervous system that controls the muscles. I would expect these cells to be...

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rat in Medical Products

Allergen, Epidermals & Animal Proteins, Rat Urine

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Allergen, Epidermals & Animal Proteins, Rat Epithelia

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Autoantibody Screen (AAS) Test Kit - Rat Kidney/Stomach Substrate

Description: Inverness Medical Professional Diagnostics is a leading provider of immunofluorescence assays, with an extensive IFA and DFA test menu that includes kits for autoimmune diseases, infectious diseases and STDs as well as miscellaneous conjugates and components. Our Impact IFA Test Systems give you a ...
Company:Inverness Medical Innovations

Free Activin AB ELISA Test

Description:...ddition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have bee...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Test

Description:...ddition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have bee...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin B ELISA Test

Description:...ddition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cell types, including cultured rat anterior pituitary cells, gonadal and neuronal cell lines, and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have bee...
Company:Diagnostic Systems Laboratories, Inc.

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rat in Medical Dictionary

Vas deferens

... However, in rat vas deferens and rat distal colon, cGMP-elevating agents such as ... In rat vas deferens , 5 mM SNP increased cGMP levels (...

Splinter

... Master Splinter , or simply Splinter is a fictional character in the Teenage Mutant Ninja Turtles universe. Splinter is a giant anthropomorphic rat who is the master of the Ninja Turtles. Kidnapped by an escaped convict (Shea Whigham) and his young accomplice (Rachel Kerbs), Seth Belzer (Paulo...

Potassium hydroxide

...ison shopping made easy. Ingredient CAS No Percent Hazardous - Potassium Hydroxide 1310-58-3 85 - 90% Yes ... For potassium hydroxide : Oral rat LD50: 273 mg/kg; Investigated as a mutagen. ... Bostick & Sullivan, the world's leading authority on handcrafted alternative photographic proc...

Malocclusion

...malocclusion ? Meaning of malocclusion medical term. What does malocclusion mean? ... The word malocclusion literally means "bad bite. ... A rat with malocclusion may salivate, rub at its mouth with its feet, or exude a ... In rat's where malocclusion exists, assess for alignment once a wee...

Lobe

...d. lobectomy. lobed comb jelly. lobed leaf. lobed spleenwort. lobefin ... 8 In the present study, a right cardiac lobe of lung from a mature rat has been ... This lobe in the adult is similar in volume to the left lung of the immature rat. ... Online Medical Dictionary and glossary with...

Leukocytes

... leukocyte adhesion to a ... Immunofluorescent Staining of Mouse and rat Leukocytes . The Uses of Fc Block™ in Immunophenotyping of Mouse or rat Leukocytes ... ... Pg was shown previously for many cells, including ...

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rat in Biological News

Limping rat provides sciatica insights

DURHAM, N.C. -- A newly developed animal model for the painful nerve condition known as sciatica should help researchers diagnose and treat it, according to Duke University bioengineers and surgeons. Sciatica is not a single disorder, but rather a diverse range of symptoms, such as numbness or ...

African thicket rat malaria linked to virulent human form

Even though the most deadly form of malaria for humans, Plasmodium falciparum , has been linked to malaria found in chimpanzees, this group has been fairly isolated on the malarial family treeuntil now. A new phylogenetic analysis from the Sackler Institute for Comparative Genomics at the America...

Dwarf cloud rat rediscovered after 112 years

CHICAGO-A team of Filipino and American scientists have rediscovered a highly distinctive mammal C a greater dwarf cloud rat C that was last seen 112 years ago. Furthermore, it has never before been discovered in its natural habitat and was thought by some to be extinct. The greater dwarf cloud ...

A new kind of rat model

Two neuroscientists at the University of Wisconsin-Milwaukee (UWM) are working with local company PhysioGenix to investigate a novel animal model the company has developed for researching diseases like depression, anxiety, schizophrenia and ADHD. The models are genetically altered rats, origin...

Human derived stem cells can repair rat hearts damaged by heart attack

When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal's heart muscle and improve function of the organ, scientists report in the September issue of Nature Biotechnology. The researchers also developed a new p...

Dopamine drug leads to new neurons and recovery of function in rat model of Parkinson's

In preliminary results, researchers have shown that a drug which mimics the effects of the nerve-signaling chemical dopamine causes new neurons to develop in the part of the brain where cells are lost in Parkinson's disease (PD). The drug also led to long-lasting recovery of function in an animal m...

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rat in Biological Technology

Transposagen Creates a Rat Model of the Human Immune System

LEXINGTON, Ky. , Aug. 6 /PRNewswire/ -- Transposagen Biopharmaceuticals, Inc. based in Lexington, KY announced today that its scientists and collaborators from the Medical College of Wisconsin have created and characterized the world's first rat model of severe combined immunodefi...

Technique for Creating Authentic Rat Embryonic Stem Cells Published in Cell

CAMBRIDGE, England, December 29 /PRNewswire-FirstCall/ -- - Technology Licensed Exclusively by Stem Cell Sciences - ("Stem Cell Sciences", "SCS", "the Company") Stem Cell Sciences plc (AIM:STEM, ASX:STC) is pleased to announce that pioneering research describing a techniqu...

Samaritan Partners 'Forgetful' Rat Model to Taconic to Commercialize

The Samaritan Alzheimer's Rat Model - Mimics Human Alzheimer's - Speeds 'Race for Time' to Find Cure - Saves Valuable Research Money LAS VEGAS, Oct. 1 /PRNewswire-FirstCall/ -- Samaritan Pharmaceuticals (OTC Bulletin Bo...

ExonHit Launches Rat Genome SpliceArray(TM) Products to Expand High Resolution Gene Expression Profiling for use in Disease Modeling and Toxicogenomics

PARIS, May 6 /PRNewswire-FirstCall/ -- ExonHit Therapeutics S.A. (Alternext: ALEHT), a drug and diagnostic discovery company, announces today the availability of its new SpliceArray(TM) for use in disease modeling and toxicogenomic applications by the basic and pre-clinical research communitie...

UW-Madison rat experiment could lead to stem-cell treatment for ALS

Madison, Wis. Scientists at the University of Wisconsin-Madison have sucessfully injected stem cells into rats' spines in a way that could lead to treatments for degenerative diseases but they did not use the controversial embryonic stem cells. The researchers inserted human stem cells deriv...

Quantitation of a Dinitro Flavonoid (DNF) in Rat Plasma Using the Varian 1200L LC/MS/MS System

D. Garteiz, R. Morrow, and B. Alexander, TexMS Analytical Services, Houston, TX C. Schmidt, Varian, Inc., Walnut Creek, CA Introduction Flavonoids are compounds that make up the pigments in fruits, vegetables, and herbs. There have been reports of flavono...

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rat in Biological Products

Goat Anti-Mouse / Rat WNK1 Polyclonal Antibody, Unconjugated from R&D Systems

Description: Mouse/Rat WNK1 Affinity Purified Polyclonal Ab...
Company:R&D Systems

Normal Rat Serum from Equitech-Bio

Description: Collected from 8-12 week old sexually mature rats. Pricing: $100/unit for 1 - 10 units...
Company:Equitech-Bio

Human, Bovine, Porcine, Rat VIP, aa 6-28 from Biotrend Chemikalien GmbH

Description: VIP (6-28) (human, bovine, porcine, rat) Vasoactive Intestinal Peptide (VIP) receptor antagonist. This carboxy-terminal VIP fragment was found to be twofold more potent than any previously described VIP receptor antagonists. Storage: Desiccate at -20 C...
Company:Biotrend Chemikalien GmbH

MagCellect Rat CD4+ T Cell Isolation Kit from R&D Systems

Description: Request Info...
Company:R&D Systems

Human / Mouse / Rat Chk1 Kinase, active ELISA development Kit, DuoSet, IC (Intracellular) from R&D Systems

Description: For the development of an immunoprecipitation assay to measure Chk1 kinase activity in cell lysates....
Company:R&D Systems

Cultrex 3D Culture Matrix Rat Collagen I from R&D Systems

Description: Cultrex 3D Culture Matrix Rat Collagen I....
Company:R&D Systems

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rat in Biological Dictionary

Zona pellucida

...es or embryos ... Whether the zona pellucida originates from the oocyte, surrounding follicle ... Development of the zona pellucida in the rat oocyte. Am J Anat. 1974 Apr;139(4) ... Zona pellucida . You don't need to be Editor-In-Chief to add or edit content to WikiDoc. ... The zona ...

Viral oncogene

...official name of this gene is "v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. ... rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog. ... ... Kidney Gene DataBase. Name. v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog ... Human ...

Tubulin

...ein-coding gene LOC572064. Represented by 26 ESTs from 16 cDNA libraries. ... Tubulin beta (LOC572064) SELECTED PROTEIN SIMILARITIES ... Norway rat protein-coding gene Tuba3a. Represented by 47 ESTs from 2 cDNA libraries. ... Rattus norvegicus tubulin , alpha 3A, mRNA (cDNA clone MGC:94913 IM...

Transversion

... efficiently extended implicating O2-Et-dT in transversion mutagenesis in vivo. ... of the oncogene neu by an A.T----T.A transversion event in rat neuroblastomas. ... The promoter sequence having this transversion has a higher promoter activity ... Nuclear dbpA expression and the T-t...

Trans-splicing

...data that contain the ... In addition, trans - splicing was not detected in COT of other mammals, such as ... reactions between COT exon 2 from rat and human do not produce trans - splicing . ... Trans - splicing appears to reflect an archaic form of RNA processing that is used ... the t...

Splicing factor

...F1. Represented by 1013 ESTs from 378 cDNA libraries. ... Homo sapiens splicing factor 1, mRNA (cDNA clone MGC:8657 IMAGE:2961666) ... Norway rat protein-coding gene Sf1. Represented by 103 ESTs from 62 cDNA libraries. ... Rattus norvegicus splicing factor 1 (Sf1), transcript variant 1, ...

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