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Randomized in Medical News

Medifocus Inc. Reports Improved Clinical Efficacy for its Phase II, Randomized Clinical Study for the Treatment of Early Stage Breast Cancer Tumors

VANCOUVER, April 15 /PRNewswire-FirstCall/ - Medifocus Inc. (TSXV:MFS) announced that positive clinical results when using the Company's proprietary focused heat treatment prior to surgery for the treatment of early stage breast cancer tumors, were presented during the Market Opening Ceremony of M...

Renal artery stenting falls short in large randomized trial

CHICAGO, Ill. (April 1, 2008) The largest-ever randomized study to evaluate the effectiveness of catheter-based interventions in patients with narrowing of the renal artery has shown that angioplasty and stenting offer no benefit over medical therapy. Among patients who completed one year of foll...

Restricting kids' video time reduces obesity, randomized trial shows

BUFFALO, N.Y. -- Entrenched sedentary behavior such as watching television and playing computer video games has been the bane for years of parents of overweight children and physicians trying to help those children lose pounds. There has been little scientifically based research on the effect o...

Cost-effectiveness of cetuximab in metastatic colorectal cancer

... Institute . Earlier, patients whose tumors harbored wild-type KRAS were found to have a higher survival advantage when treated with cetuximab in a randomized trial by the National Cancer Institute of Canada Clinical Trials Group. In this study, Nicole Mittmann, of the HOPE Research Centre Sunnybrook He...

Electronic Health Records Help Cardiac Patients Remain Healthy

...h their care givers electronically, according to a randomized study by Kaiser Permanente published in The Americ...Managed Care this month. This is the first randomized study to evaluate a follow-up system for patients ... and effective medication management. The two-year randomized trial of 421 patients found that patients discharg...

Guided care reduces cost of health care for older persons with chronic conditions

...opkins Bloomberg School of Public Health. The research, published in the American Journal of Managed Care , found that in the first eight months of a randomized controlled trial, patients in a primary care enhancement program called "Guided Care" spent less time in hospitals and skilled nursing facilities and ...

Men With Angina Do Worse Than Women

...ipants are carefully matched, he said. "Treatment was decided upon not by randomization but just by defining the condition," Fonarow said. "You need a randomized clinical trial to get definitive results." But the difference in outcome between men and women appears real, although the reasons for it remain unk...

Stroke Doubles Risk of Hip, Thigh Fractures

...he journal Stroke . "We know from other studies that bone loss starts rapidly after stroke," de Vries said. "Furthermore, there is evidence from a randomized controlled trial in an Asian population that administration of bisphosphonates, bone-protecting agents, immediately after a stroke reduces bone loss a...

Brain Fitness Reduces Risk of Onset of Depressive Symptoms

...us universities to design and test its interactive computer-based programs. More than 30 articles in leading science and medical journals show that in randomized controlled trials the company's patented technologies significantly increase processing speed, improve memory and attention and enhance quality of lif...

Pilot study: Workplace yoga and meditation can lower feelings of stress

...ers recruited 48 adult office workers with body mass index scores lower than 30 who exercised less than 30 minutes on most days of the week. Half were randomized to the intervention and half were wait-listed to receive the intervention later. Forty-two people completed the study. Those who received the inter...
Randomized in Medical Technology

West Wireless Health Institute Teams with Corventis for its First Multicenter, Randomized Clinical Trial

Collaboration will test remote wireless monitoring to prevent hospital readmissions for heart failure SAN DIEGO, June 24 /PRNewswire-USNewswire/ -- The West Wireless Health Institute (WWHI), one of the world's first medical research organizations dedicated to advancing health and well-being t...

Long Term Data Presented at EuroPCR 2009 from Randomized Study Attest to Durability of Results of OrbusNeich's Genous(TM) Bio-engineered R stent(TM) Compared to Drug-Eluting Stents

Other Presentations Highlight Pre-clinical Work of Company's Future Pro-healing Technologies BARCELONA, Spain, May 20 /PRNewswire/ -- OrbusNeich announced today that two year follow up data from a single center, randomized clinical study in patients at high risk of restenosis were presented a...

Isis Announces That OGX-011 Has Shown Overall Survival Advantage in Prostate Cancer Compared to Standard Therapy in a Randomized Phase 2 Study

CARLSBAD, Calif., Dec. 3 /PRNewswire-FirstCall/ -- Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ) announced today that OncoGenex Pharmaceuticals, Inc. provided positive survival results from a randomized Phase 2 clinical trial of OGX-011 in combination with docetaxel and prednisone ("the OGX-011 arm...

Evalve Announces Enrollment Completion of the EVEREST Randomized Study

EVEREST Becomes First Trial of its Kind to Achieve Enrollment Milestone MENLO PARK, Calif., Sept. 30 /PRNewswire/ -- Evalve, Inc., the leader in the development of devices for the percutaneous repair of cardiac valves, announced today the completion of randomized enrollment in the Endovascular...

Concentric Medical to Sponsor Randomized Trial

MOUNTAIN VIEW, Calif., Sept. 23 /PRNewswire/ -- Concentric Medical, Inc., the global leader in devices for clot removal in ischemic stroke patients, today announced its plan to sponsor a prospective randomized clinical trial comparing intervention using the Merci Retrieval System(TM) with best...

Logical Therapeutics Inc. Commences Double-Blind, Randomized Study of Their Lead Program, LT-NS001

WALTHAM, Mass., Sept. 8 /PRNewswire/ -- Logical Therapeutics, Inc., announced today the commencement of its double-blind, randomized, active-controlled, multinational study of LT-NS001, a novel prodrug, which is converted in the bloodstream to naproxen, a non-steroidal anti-inflammatory drug (...

Human Genome Sciences Reports Initial Results of Randomized Phase 2 Trial of HGS-ETR1 in Combination With Bortezomib in Advanced Multiple Myeloma

- First of three ongoing randomized chemotherapy combination trials to evaluate HGS-ETR1 in the treatment of specific cancers - ROCKVILLE, Md., Sept. 2 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI ) today reported initial topline results from an ongoing randomiz...

Human Genome Sciences Completes Enrollment in Randomized Phase 2 Trial of HGS-ETR1 in Non-Small Cell Lung Cancer

ROCKVILLE, Md., Aug. 22 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI ) today announced that it has completed the enrollment and initial dosing of patients in a randomized Phase 2 trial of HGS-ETR1 (mapatumumab) in combination with the chemotherapy agents paclitaxel and ...

Telik Announces Initiation of Two Phase 2 Randomized TELINTRA Studies

PALO ALTO, Calif., May 20 /PRNewswire-FirstCall/ -- Telik, Inc. (Nasdaq: TELK ), today announced it has initiated two Phase 2 TELINTRA(R) studies -- one with TELINTRA tablets in myelodysplastic syndrome, or MDS, and a second with TELINTRA tablets in cancer patients at risk for chemotherapy-in...

Data from Randomized Pilot Study, Real-World Use of OrbusNeich's Genous(TM) Bio-engineered R stent(TM) to be Presented in Symposium at EuroPCR 2008

Other Data Presentations to Focus on Use of Pro-Healing Stent with AMI Patients and Those Who Cannot Tolerate Dual-Antiplatelet Therapy HONG KONG, May 8 /PRNewswire/ -- Twelve-month follow-up data from both a randomized pilot study and the real-world registry use of OrbusNeich's Genous Bio...
Randomized in Medical Products

CSV-1OOOE Contrast Sensitivity Test Face

Description:...interested in using the CSV-1000E in research studies, the test face is available in two versions. The CSV-1000E Contrast Sensitivity Chart 1 provides randomized locations for the grating targets....
Company:VectorVision

The VNUS Closure System

Description:...eters, physicians can treat incompetent saphenous, perforator and tributary vessels with minimal post-operative pain and bruising. Numerous published randomized and multi-center clinical studies, now with 5 year follow-up results, verify the effectiveness and durability of the VNUS Closure procedure ( www.vn...
Company:VNUS Medical Technologies, Inc.

FilterWire EZ Embolic Protection System

Features:... Fewer Complications: Reduces major adverse events associated with SVG interventions. The BLAZE Registry shows comparable results to the randomized FIRE Trial, confirming the safety and performance of the FilterWire EZ System. Conforming filter frame is designed to ensure reliable wall appo...
Company:Boston Scientific Corporation
Randomized in Medical Definition

Ultrasound-enhanced systemic thrombolysis

...Stroke thedoctorslounge.net Ultrasound-enhanced systemic thrombolysis for acute ischaemic stroke druginfozone.nhs.uk CLOTBUST: Design of a randomized Trial of Ultrasound-Enhanced Thrombolysis for Acute Ischemic Stroke sagepub.com Combined Lysis of Thrombus in Brain Ischemia with Transcranial U...
Randomized in Medical Dictionary

Toxic nodular goiter

...ion ... Many patients with a toxic goiter may not have elevated levels of ... reduction of benign nontoxic nodular goiter : a prospective randomized double-blind trial. ... Toxic nodular goiter involves an enlarged thyroid gland that contains a small ... Toxic nodular goiter arise...

Stress management

... 2 Models of stress management . 2.1 Transactional model ... Individualized Stress Management for Primary Hypertension: A randomized Trial" ... Collection of articles to help people cope with stress . Includes tips on getting together with family and how stress affects t...

Insulin

...dy can't process glucose to keep it ... Supplemental short-acting insulin will be given for hyperglycemia before meals. ... Subjects will be randomized to Apidra or regular insulin in a 1:1 fashion. ... The American Journal of Hypertension, a peer reviewed journal, provides a forum for scientifi...

Infants

...infants and babies - Overview. ... Infants who are infected are either infected because their mothers were infected ... There were 26 infants randomized to repair within 4 hours of arrival (all but ... In the Nio study, the infants in the delayed surgery arm underwent surgery at a ... Until r...

Anastomosis

...n result from trauma or ... Abstract and Introduction: A prospective, randomized comparison of a manual esophagogastric anastomosis in the neck with a sta...gogastric anastomosis in the ... Patients and Methods: A prospective, randomized comparison of a manual esophagogastric anastomosis in the neck with a sta...

Acute mountain sickness

...meters. Acute Mountain Sickness and hi carolHigh-Altitude Cerebral Edema. ... Sumatriptan for prevention of acute mountain sickness : randomized clinical trial" ... Acute mountain sickness is brought on by the combination of reduced air pressure ... The chance of getting acute moun...
Randomized in Biological News

Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial

Women who took beta carotene or vitamin C or E or a combination of the supplements had a similar risk of cancer as women who did not take the supplements, according to data from a randomized controlled trial in the December 30 online issue of the Journal of the National Cancer Institute. Epid...

Most older long-term cancer survivors have poor health habits

...ve effect of regular exercise and a healthy diet on physical quality of life outcomes among older, long-term cancer survivors," said Dr. Mosher. "Only randomized clinical trials, however, can reveal whether lifestyle modification improves older, long-term cancer survivors' physical outcomes," she added. ...

Avoiding hysterectomy: Major interventional radiology E-collection info available

...n After Uterine Artery Embolization: A Prospective randomized Study Comparing Tris-acryl Gelatin Microspheres Versus Polyvinyl Alcohol Microspheres," a randomized study by Gary P. Siskin, M.D., FSIR, and colleague... of Symptomatic Uterine Fibroids: Results From the randomized EMMY Trial" and "Payer Costs in Patients Undergoin...

Probiotics help gastric-bypass patients lose weight more quickly, Stanford study shows

...es at Stanford Hospital & Clinics. The researchers followed 44 patients on whom Morton had performed the procedure from 2006 to 2007. Patients were randomized into either a probiotic or a control group. Both groups received the same bariatric medical care and nutritional counseling, as well as the support of...

Two dietary oils, two sets of benefits for older women with diabetes

... treat the disease. Many did take other medications, such as those used to manage blood sugar levels, cholesterol or blood pressure. The women were randomized into two groups to determine which supplement they took first. Each initial 16-week supplementation was followed by a four-week washout period to remo...

Laboring without the labor bed: It's a good thing

...he behaviour of everyone in it the laboring women as well as those who provide care for her. Hodnett hopes to further this study with a larger, randomized controlled trial. ...

Debate on admin. of magnesium sulfate to pregnant women to prevent cerebral palsy in pre-term infants

...University, Detroit, conducted a systematic review and meta-analysis of six randomized controlled trials involving 4796 women and 5357 infants. Writing in the art... on the use of MgSO4 to prevent cerebral palsy. He notes that "three large, randomized placebo-controlled trials of antenatal magnesium sulfate (MgSO4) for fetal ...

Green tea may affect prostate cancer progression

... relating to green tea components. "Unfortunately, this trial was not a randomized trial, which would have been needed to be more sure that the observed chang.... However, "this trial is provocative enough to consider a more substantial randomized trial." In collaboration with Columbia University in New York City, the ...

Study shows CGM devices also benefit people with type 1 diabetes

...ellent blood sugar control. The CGM study was a randomized and controlled trial involving 129 adults and chil...f hypoglycemia in adults over 25 years of age in a randomized trial of 322 adults and children with type 1 diabe... study group also conducted a separate, concurrent randomized trial to evaluate the efficacy and safety of CGM i...

Biolex presents Locteron US Phase 2a hepatitis C data at EASL

...PLUS trial was designed to evaluate the safety and tolerability of Locteron, and to directly compare Locteron with pegylated interferon. Patients were randomized to receive either Locteron (administered once every two weeks) or PEG-Intron (administered once per week). The Locteron doses evaluated in the PLUS tr...
Randomized in Biological Technology

NIMOTUZUMAB DEMONSTRATES EFFICACY IN RANDOMIZED HEAD & NECK CANCER STUDY WITHOUT THE TOXICITIES ASSOCIATED WITH OTHER EGFR DRUGS

- Results from a randomized Phase IIb trial reported at 2009 ASCO Annual Meeting - MISSISSAUGA, ON, June 1 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Amex: YMI , TSX:YM, AIM:YMBA), a life sciences product development company that identifies and advances a diverse portfolio ...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

Webcast at 7:10 p.m. Eastern Time Today BOTHELL, WA, and VANCOUVER, May 30 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI ) today announced the final results of a Randomized Phase 2 Trial presented during an oral presentation at the American Society of Clinical Oncol...

YM BIOSCIENCES ANNOUNCES RESULTS OF RANDOMIZED NIMOTUZUMAB STUDY TO BE PRESENTED IN A POSTER AT ASCO ANNUAL MEETING

MISSISSAUGA, ON, May 28 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Amex: YMI , TSX:YM, AIM:YMBA), an oncology company that identifies, develops and commercializes differentiated products for patients worldwide, today announced that a poster presentation will report results from a randomiz...

OncoGenex Pharmaceuticals Announces Release of Two ASCO Abstracts: Impact of OGX-011 on Survival in Randomized Phase 2 Trial and Phase 1 Safety Data for OGX-427

BOTHELL, WA and VANCOUVER, May 14 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI ) today announced the release of two abstracts to be presented during oral presentations at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting. Abstracts are now availab...

Nereus Pharmaceuticals Initiates ADVANCE, a Randomized Phase 2 Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer

SAN DIEGO, March 23 /PRNewswire/ -- Nereus Pharmaceuticals, Inc., a pioneer in drug discovery from marine microbial sources, today announced that it is conducting a randomized Phase 2 clinical trial evaluating the vascular disrupting agent (VDA) NPI-2358 in combination with standard chemotherapy (...

Aegera Therapeutics Initiates A Randomized Phase 2 Combination Study of AEG35156 for 1st Line Treatment of Non-Small Cell Lung Cancer

MONTREAL, Jan. 8 /PRNewswire/ - Aegera Therapeutics Inc. announced today the dosing of the first patient in a randomized Phase 2 study of AEG35156, their targeted antisense therapeutic in mid-stage development for multiple oncology indications. The study, entitled "A Phase 2, Multicenter, Open-L...

YM BIOSCIENCES RECEIVES CLEARANCE TO INITIATE RANDOMIZED DOUBLE-BLIND CLINICAL TRIALS OF NIMOTUZUMAB IN LUNG CANCER AND BRAIN METASTASES FROM LUNG CANCER

MISSISSAUGA, ON, Jan. 5 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Alternext US:YMI, TSX:YM, AIM:YMBA), an oncology company that identifies, develops and commercializes differentiated products for patients worldwide, today announced that it has received clearance from Canadian regulatory a...

OGX-011 Shows Overall Survival Advantage in Prostate Cancer Compared to Standard Therapy in a Randomized Phase 2 Study

First-line trial currently shows median overall survival of 27.5 months for OGX-011 in combination with docetaxel and prednisone and a 16.9 months overall survival for docetaxel and prednisone alone. Achievement of survival benefit milestone results in release of ...

Sloning and the Kornberg group at Stanford University starting evaluation project regarding the synthesis of a Statistically Randomized Gene Library

Munich, Germany, April 24, 2008 / b3c newswire / - Sloning BioTechnology and Roger Kornberg’s group at Stanford University are working on a project to synthesize a gene mutant library where selected codons are introduced in a statistically expected and controlled ratio at preselected posi...

Human Genome Sciences Initiates Second Randomized Phase 2 Trial of HGS-ETR1 in Combination With Chemotherapy

ROCKVILLE, Md., Dec. 20 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI ) announced today that it has initiated dosing of patients in a Phase 2 clinical trial of HGS-ETR1 (mapatumumab) in combination with the chemotherapy agents paclitaxel and carboplatin as first-line the...
Randomized in Biological Definition

Cancer

...nd specific cancers. Evidence is now emerging from randomized controlled trials designed to test whether interve...ventions, e.g., exercise. Contrary to expectation, randomized trials found no benefit of beta-carotene supplem... beta-carotene arms of 2 of the trials. Similarly, randomized controlled trials have found no reduction in risk ...

Diabetes mellitus

...rimary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicenter randomized placebo-controlled trial. Lancet 2004; 364: 685-96 MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk in...
Randomized in Biological Dictionary

Transmembrane proteins

...2009 ... Manipulation of cell behavior with small transmembrane proteins ... Figure TM.1 Scheme to isolate small transforming proteins with randomized transmembrane domains. ... Introduction - This is the electron crystal ... Here is one transmembrane helix. ... molecules bound to the transme...

Ribosome binding site

... site , called the acceptor site ... The three tRNA binding sites of the ribosome —A (acceptor), P (peptidyl), and E ... 185 clones with randomized ribosome binding sites , from position -11 to 0 ... structure of the ribosome binding site determines translational efficiency: a ... .....

Epinephrine

...eleased into the bloodstream in response to physical or mental Hypersensitivity to epinephrine or any component of the ... Eligible patients were randomized to intravenous vasopressin (40 units) or epinephrine (1 mg) ... All about Epinephrine . View complete and up to date Epinephrine information -...
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