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Raloxifene in Medical News

Lilly Granted Preliminary Injunction to Prevent Launch of Generic Raloxifene

Lilly Continues to Defend Intellectual Property Rights for Evista INDIANAPOLIS, April 22 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY ) announced that the U.S. District Court for the Southern District of Indiana today issued a preliminary injunction to prevent the launch of a ...

Lilly Granted Temporary Restraining Order to Halt Launch of Generic Raloxifene

Lilly Vows to Defend Intellectual Property Rights INDIANAPOLIS, March 9 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY ) today issued the following statement after being granted a temporary restraining order to halt the launch of a generic version of Evista(R) (raloxifene HCl ta...

V. Craig Jordan, Internationally Renowned Breast Cancer Scientist, Joins Georgetown's Lombardi Comprehensive Cancer Center

...as the "gold standard" for endocrine therapy of breast cancer for 25 years. A related drug and SERM, raloxifene, also came from Jordan's laboratory. raloxifene is used both for the prevention of breast cancer and osteoporosis. Jordan's distinguished list of national and international awards includes the...

NCCN Updates Breast Cancer and Breast Cancer Risk Reduction Guidelines

...pany). Tamoxifen is recommended for premenopausal women with a history of atypical hyperplasia to reduce breast cancer risk. For postmenopausal women, raloxifene is listed as equivalent to tamoxifen in reducing the risk of developing invasive breast cancer; however, it did not provide the same level of risk red...

Raloxifene Cuts Risk of Certain Type of Breast Cancer

...women. A new analysis finds that those who took raloxifene (Evista) regularly over a number of years were les...compared with women who did not take the drug. raloxifene did not, however, cut the risk for noninvasive bre...ancers. "This is a reaffirmation that the drug raloxifene is a very powerful SERM [selective estrogen recept...

Anti-estrogen drug therapy reduces risk of invasive breast cancer in older women

...tive for certain cancers. Women who took the drug raloxifene were less likely to develop invasive, estrogen-rec...to breast cancer (National Cancer Institute). raloxifene is a selective estrogen receptor modulator (SERM),... prior hormone use or baseline breast cancer risk, raloxifene reduced the risk of hormone responsive (ER-positiv...

Raloxifene Safe for Women With Decreased Kidney Function

... April 9 (HealthDay News) -- The osteoporosis drug raloxifene is safe and effective for women with mild to moder...oporosis who took part in the Multiple Outcomes of raloxifene Evaluation (MORE) trial. The authors examined raloxifene effects over three years on the rate of bone miner...

Ten Things You Can Do to Reduce Your Cancer Risk

...hould talk with their doctor about the pros and cons of these medications given their risk for the disease. These include: * Breast: Tamoxifen and raloxifene both reduce the chance of developing breast cancer by half in women at increased risk for the disease. Women at increased risk include those over age ...

Moving beyond tamoxifen: Drug discovery and the future of selective hormone receptor modulators

...cules inside cells that bind to estrogen and other hormones, nearly half are able to be regulated in some way. Our knowledge of how tamoxifen and raloxifene work is now being applied to develop new drugs that are selective male hormone receptor modulators that could be used in men to improve muscle weight ...

Many Osteoporosis Medications Prevent Fractures, But None Is Proven Best

...report. Some agents, however, such as estrogen and raloxifene (a SERM), can have serious side effects such as st...plus calcitonin, parathyroid hormone, estrogen and raloxifene prevent spinal fractures. Evidence also showed tha...nate, calcitonin, teriparatide (a form of PTH) and raloxifene reduce fracture risks. -- Not enough evidence ...
Raloxifene in Medical Technology

Phase III Trial Showed Investigational Compound Arzoxifene Was Superior to Evista(R) (raloxifene HCl) in Increasing BMD in Postmenopausal Women with Osteoporosis

...nificantly Suppressed Bone Turnover Markers versus raloxifene in Postmenopausal Women with Osteoporosis ATH...strogen receptor modulator (SERM), was superior to raloxifene at increasing bone mineral density (BMD) in the lu...nasopharyngitis in the arzoxifene group versus the raloxifene group, whereas significantly fewer women reported ...

First Patient Enrolled in Global Phase III Study of Bevacizumab and Trastuzumab in Early Breast Cancer

...e breast cancer prevention studies that showed that the drugs tamoxifen and raloxifene could reduce the risk of developing invasive breast cancer by about 50 perc...ted in the Breast Cancer Prevention Trial (BCPT) and Study of Tamoxifen and raloxifene (STAR). Additional information about the NSABP is available on the Intern...

Wyeth Presents Phase 3 Fracture Data for Bazedoxifene, an Investigational Therapy for Osteoporosis

... 2.3 percent and 4.1 percent in the bazedoxifene 20 mg, bazedoxifene 40 mg, raloxifene 60 mg and placebo groups, respectively. In addition, a subgroup analysis o...ent, 5.9 percent and 6.3 percent in bazedoxifene 20 mg, bazedoxifene 40 mg, raloxifene 60 mg and placebo groups, respectively, with a risk reduction of 46 percent...

FDA Approves Lilly's Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women

...was updated to include safety information from the raloxifene Use for The Heart (RUTH) trial, which evaluated po...stmenopausal women: -- The Study of Tamoxifen and raloxifene (STAR) trial, sponsored by the National Cancer Ins...nd tamoxifen 4.3, per 1000 women per year. -- The raloxifene Use for The Heart (RUTH) trial looked at postmenop...
Raloxifene in Biological News

Quest for better treatment for effects of menopause

...ach of the treatments. To this end, Doctor Ruiz del Agua analysed the response by a group of women from Bizkaia to two treatments: on the one hand, to raloxifene and, on the other, to a substitutive hormonal treatment combining estradiol (a type of oestrogen) and progesterone (another female sex hormone). T...

Tamoxifen-like drug suggests new ways to selectively block estrogen

...esearchers understand why drugs like tamoxifen and raloxifene behave the way they do, simulating the effects of ...les that would be more effective than tamoxifen or raloxifene at preventing breast cancer, heart disease and bon... the risk of endometrial cancer." Tamoxifen and raloxifene are the best-known members of a class of drugs kno...
Raloxifene in Biological Technology

Retrospective Analysis of Phase 3 Data Suggest Wyeth's Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms

...ational compound bazedoxifene (BZA) alone did not appear to increase mammographic breast density in postmenopausal women with osteoporosis compared to raloxifene (the active comparator) or placebo over two years. BZA is an investigational selective estrogen receptor modulator (SERM) under development for the tr...

Prix Galien USA Announces 2008 Final Candidates

...- CV Therapeutics Inc. - Ranexa(R) (ranolazine) -- Elan Corporation - Prialt(R) (ziconotide intrathecal infusion) -- Eli Lilly Company - Evista(R) raloxifene HCI -- Genzyme Corporation - Myozyme(R) -- GlaxoSmithKline - Tykerb(TM) (lapatinib) and Altabax(TM) (retapamulin ointment) -- Merck & Co. - Isen...
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