Viral DNA sequence a possible trigger for breast cancer
A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigger for bre...New binding target for oncogenic viral protein
The DNA tumor virus simian virus 40 produces the Large T antigen which inactivates two of the cell's most important cancer-preventing proteins, p53 and pRb. In a study published in the Journal of Biological Chemistry, researchers at the Fred Hutchinson Cancer Research Center report the discovery of an additional target for T antigen--a protein called Fbw7. The Fbw7 gene is located in a ch...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
The genome sequence of the parasitic amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety of bacterial-like genes that contribute to the organism's unique biology. The report, which appears in the February 24 issue of Nature, presents the first genome-wide study...Novel antiviral technology inhibits RSV infection in mice
A novel antiviral treatment combiningnanoparticle and gene silencing technologies thwarts attacks ofrespiratory syncytial virus (RSV) -- a virus associated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lung cells and can be life-threatening in very...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
New York University biologists have uncovered how the innate immune system in mice's brains fights viral infection of neurons. The findings, published as the cover study in the latest issue of Virology, show that proteins in neurons fight the virus at multiple stages--by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brai...NeuroCyte - Rat Neural Stem Cell Kit from Orion BioSolutions, Inc.
Description:Rat Neural Stem Cell Kit with Medium High quality ready-to-use cryopreserved neural stem cells (NCSs) complete with optimized base medium for growth and lineage commitment. Just thaw and plate these unique cells generated from E18 fetal rat brain in the format you need for a tissue-like mixture of in vitro stem/progenitor cells, neurons, astrocytes and oligodendrocytes. Better than neurospheres...Human and Mouse RAR Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-005 is a synthetic peptide whose sequence is from the C-terminal end of the mouse retinoic acid receptor beta (RAR*). The 21 amino acid sequence extends from amino acids 429 to 448 of RAR*. The sequence of PEP-005 is (amino to carboxy terminus): C - P - S - V - S - P - S - S - V - E - N - S - G - V - S - Q - S - P - L - L - Q (The N-terminal cysteine has been added to facilitate conjugatio...Rat rab 3D Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-126 is an 18 amino acid synthetic peptide whose sequence corresponds to residues 1-18 from rat rab 3D. The sequence of this peptide is (amino to carboxy terminus): M(1) - A - S - A - S - E - P - P - A - S - P - R - D - A - A - D - Q - N(18). This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat rab 3D, cata...Rat SAP97 Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-055 is a 20 amino acid synthetic peptide whose sequence corresponds to residues 115-133 of rat SAP97. The sequence of this peptide is (amino to carboxy terminus): V115 - L - P - S - E - R - I - S - P - Q - V - P - N - E - V - L - G - P - E133 (C) (The C-terminal cysteine has been added to facilitate conjugation and is not a part of the native rat SAP97 sequence.). This peptide may be u...Functional Cloning Using ViraPort Retroviral cDNA Expression Libraries
Retroviral libraries with high-titer efficiency and larger insertpotential ViraPort Retroviral cDNA Expression Libraries Katherine Felts Kim Zaharee Latha Sundar JamieLimjoco Anna Waesche Peter Vaillancourt Stratagene We introduce a set of human cDNA expression li...Versatile Reporter Vectors for Monitoring Viral Transduction
Determine retroviral transduction efficiency and gene expression invirtually any target cell line Stratagene , pFB-Neo-LacZ <font...pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins
Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...High-Titer Retroviral Vectors for Gene Delivery
High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...Neutral theory of molecular evolution
. Although the theory was received b...Bypass Heart Surgery Performed Without General Anesthesia
A minimally invasive direct coronary artery bypass (MIDCAB) procedure was performed at Pittsburgh while the patient was awake. The operation was done under thoracic epidural anesthesia. This approach may help in discharging the patient early from the hospital. Dr. Zenati from the team of doctors who performed the surgery said that patients who are operated in this way may not have to go t...General Anesthesia Safe For Children On Ketogenic Diet Suffering From Epilepsy
Epileptic children have always been ostracized as children of a lesser God. The physical, mental, moral and social ramifications of these hapless children are beyond words. One stumbling handicap in the surgical treatment of such children was the feasibility of administering General Anesthesia to these children. In many cases the anesthesia times ranged from 1 to 10 hours with procedur...Beware of the oral patch! It could be cancer!!!
Oncologists have warned that the common white patches found inside the mouth can lead to oral cancer in many cases. A simple genetic test can help pinpoint if the patches could become cancerous or not.Scientists at the University of Oslo spearheaded this research. If identified early and treated, leukoplakia, as the patches are known, can be cured and the occurrence of cancer prevented....GLEEVEC - An Oral treatment for leukemia
The U.S.Food and Drug Administration (FDA) at a conference in Washington, approves the new leukemia drug-GLEEVEC, first of its kind that directly removes the sign of a protein known to cause cancer. It is given as an oral treatment for chronic myelogenous leukemia (CML). Other molecular-targeting drugs previously approved by the FDA interfere with proteins associated with other cancer...GLEEVEC - An Oral treatment for leukemia
The U.S.Food and Drug Administration (FDA) at a conference in Washington, approves the new leukemia drug-GLEEVEC, first of its kind that directly removes the sign of a protein known to cause cancer. It is given as an oral treatment for chronic myelogenous leukemia (CML). Other molecular-targeting drugs previously approved by the FDA interfere with proteins associated with other cancer...McNeil-Goldman Scleral and Blepharostat Ring
Description:Adult size. Loops retract lids. Polished finish....McNeil-Goldman Scleral and Blepharostat Ring - Pediatric
Description:Pediatric size. Loops retract lids. Polished finish....Temporal Approach Lid Speculum
Description:Angled for temporal approach. Open 14 mm rounded blades for patient comfort. Dull finish....Temporal Approach Lid Speculum - Wire Blade
Description:Angled for temporal approach. Wire 14 mm rounded blades for patient comfort. Dull finish....Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
- Results Fail to Demonstrate Meaningful Placebo Adjusted WeightLoss; Obesity Program to be Discontinued NEW YORK, July 09, 2007 /PRNewswire-FirstCall/ -- ManhattanPharmaceuticals, Inc. today announced results of the company's twoPhase 2a clinical trials of oral Oleoyl-estrone (OE). The resultsof both randomized, double-blind, placebo-controlled studies, onein common obesity and the other...Beike Biotechnology Study Suggests Adult Stem Cells Show Promise for Peripheral Vascular Disease
Adult stem cells cultivated from patients' own blood canpotentially improve the quality of life for patients whose lowerextremities are affected by peripheral vascular disease, accordingto a study in China. SHENZHEN, China, July 02, 2007 /PRNewswire/ -- BeikeBiotechnology Co., Ltd. (<a target="_blank" href="http://www.beikebiotech.com/">http://www.beikebiotech.com )today announced tha...