Radioligand

Two Scientists Join Team of Biomoda, Inc.

...rmerly worked as a research assistant in the clinical studies of multiple assays, including in vivo microdialysis, cell isolation, tissue preparation, radioligand binding assays and protein quantification. Biomoda's technology is based on a patented porphyrin application that preferentially binds to cancerous o...

Radioligand in Biological Technology

Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

Vronique Brechler, David Handfield, Martin Boissonneault, Esther Tremblay, Benoit Houle and Luc Mnard. Introduction Recent advances in combinatorial chemistry and genomics programs have led to an unprecedented increase in both the number of compounds and potential...

AstraZeneca and Banner Alzheimer's Institute Collaborate to Evaluate New Tool Targeting Alzheimer's Disease

...cus on the evaluation and further development of a radioligand discovered by AstraZeneca. This radioligand is a molecule that binds to amyloid plaque -- prot...setting is ideal for further evaluation of our new radioligand with the potential for detailed mapping of amyloid...

Receptor Binding Assays using Fluorescence Polarization Detection: the [FP]2TM Characterized Tracers

...ecisions , Moraga, CA. 4. Allen, M., Reeves, J., Mellor, G. (2000). High throughput fluorescence polarization: a homogeneous alternative to radioligand binding for cell surface receptors. J. Biomol. Screen. 5:63-70. 5. Banks, P., Gosselin, M., Prystay, L. (2000). Fluorescence polarization...

Direct Counting of Millipore MultiScreen Filtration Plates.

...ition curve was prepared, following the instructions provided with the reagents. After incubation, the ligand-receptor complex was separated from free radioligand on the MultiScreen vacuum manifold (Millipore Cat. No. MAVM09601). The plate was then dried and snapped into the adapter (Packard # PPN 6005178). 25 m...

In Vitro Measurement of the Second Messenger cAMP: RIA vs. FlashPlate

...rmination. In addition, the use of this technology does not stop at second messenger assessment, but can be applied to all RIA applications as well as radioligand binding and guanine nucleotide binding protein assays, development of which is eagerly awaited. Reference 1. McHale, M., et al ...

Cell lines expressing recombinant aequorin and a G-protein coupled receptor for functional screening

...s functional screening assay has been tested with several kinds of G-protein coupled receptors. EC 50 values are similar to affinity values obtain by radioligand binding and/or other functional assays. Human chemokine CCR5 receptor: A CHO cell line expressing the chemokine CCR5 receptor, ...

Screening for β2-adrenergic receptor agonists using the pH-sensitive dye,CypHer5, and the IN Cell Analyzer 3000

...erminally VSV-G epitope-tagged β 2-adrenergic receptor was established using standard methods and assessed for receptor expression levels using radioligand binding studies (approximately 1.8 pmol/mg cell homogenate). The assay measuring β 2-adrenergic receptor internalization into acidic endosomal ...

Radioligand in Biological Products

Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer

Description:...ine) is a specific ligand for the FM3 and FM4 receptors. The physiological roles of these receptors are not fully determined. The availability of this radioligand will facilitate the characterization of these receptors.\n\n\nWarning\n\nThis product contains a chemical (s) known to the state of California to caus...
Company:PerkinElmer

Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer

Description:...ine) is a specific ligand for the FM3 and FM4 receptors. The physiological roles of these receptors are not fully determined. The availability of this radioligand will facilitate the characterization of these receptors.\n\n\nWarning\n\nThis product contains a chemical (s) known to the state of California to caus...
Company:PerkinElmer