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RUNX2 in Medical News

Research Identifies Osteoporosis Controlling Protein

...a transcription factor that is the master regulator of osteoblast differentiation, which activates key bone formation genes. By removing Shn3 or WWP1, runx2 doesnt degrade, which leads to increased bone mass. The authors believe that targeting Shn3 and WWP1 for drug discovery is an exciting prospect. G...
RUNX2 in Biological News

Engineers create bone that blends into tendons

...n as Runx2. They generated a high concentration of runx2 at one end of the scaffold and decreased that amou...of the scaffold containing a high concentration of runx2 turned into bone, while the skin cells on the scaffold end with no runx2 turned into soft tissue. The result is an artifici...

Signaling for cartilage

...e way versus another,?said Lee. Both SOX9 and runx2 are master transcription factors involved in the p...er, he said, the primordial skeletal cell has both runx2 AND SOX9. “We then asked a simple question: C...n it is present in a progenitor cell, it turns off runx2 and allows the cell to become cartilage.? That...

Research identifies protein in mice that regulates bone formation

...a transcription factor that is the master regulator of osteoblast differentiation, which activates key bone formation genes. By removing Shn3 or WWP1, runx2 doesnt degrade, which leads to increased bone mass. The authors believe that targeting Shn3 and WWP1 for drug discovery is an exciting prospect. Gl...
RUNX2 in Biological Products

Rat Anti-Human CBFA1 / RUNX2 Monoclonal Antibody, Unconjugated, Clone 232902 from R&D Systems

Description: Human RUNX2/CBFA1 MAb (Clone 232902)...
Company:R&D Systems
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