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RPE in Medical News

UF scientists program blood stem cells to become vision cells

...ose to build retinal pigment epithelial cells, which form the outer barrier of the retina. In addition to being very specialized and easy to identify, rpe cells are faulty in many retinal diseases, including age-related macular degeneration, which affects nearly 2 million people in the United States, and...

Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration

...s, "There were two very encouraging findings: rpe stem cells injected into the suprachoroidal space prevented the animal's rpe cell's degeneration as well as preventing degenera...of degeneration in the fellow eye. Degeneration of rpe cells occur in many other human retinal diseases s...

LSUHSC research identifies enzyme that makes survival molecule for key vision cells

... the survival of rod and cone photoreceptor cells. rpe cells regulate the renewal of the tips of photoreceptor cells among other functions. When rpe cells do not function properly, photoreceptor cell...mber of stressors, including free radicals, damage rpe cells. Dr. Bazan's lab has shown that...

'Dark cells' of living retina imaged for the first time

... The cells, called retinal pigment epithelial, or rpe cells, are nearly black, and form a layer that rec... shuttled out of the photoreceptor and down to the rpe cells. The rpe cells recharge the photopigment molecules and send...

Ellex Announces New Retina Regeneration Therapy to be Presented at the AAO

... preserve vision. Laboratory research conducted under Professor Marshall over the past few years has demonstrated that the Ellex 2RT method causes the rpe to migrate and release matrix metalloproteinase (MMP's), which are the enzymes that clean up Bruch's membrane. Further laboratory experiments to measu...

Stem Cell Therapy Could Provide Cure for AMD in Five Years

...ls, which are effective in replacing dysfunctional rpe and photoreceptors found in AMD, leading to a surg... cells in Sheffield, confirming that the cells are rpe cells and preparing them in a form for transplant ...ction based on studies on transplanting autologous rpe (i.e. cells from the patients' own eyes) at Moorfi...

Biologists Trace Cause Of Early Blindness To Tissue Defect

.... Their results suggest therapies that correct the rpe may successfully rescue photoreceptor loss in chor...eceptors was perfectly normal, but the neighboring rpe was defective, which is why the photoreceptors wer...nctional gene can potentially be added back to the rpe using gene therapy.” In addition to being ...

Cell transplantation - Potential treatment for blindness

...was cultured from human embryonic stem cell lines. rpe are the cells that support the light sensing cells in the eye. The cultured rpe was then transplanted into the eyes of a special breed of rat that had an rpe defect, resulting in blindness. It was found that ...

Another feather in fish oil cap: hope against retinal degenerative diseases

... acid signaling, neuroprotection and photoreceptors.' Dr. Bazan's LSUHSC group, in collaboration with Harvard, has revealed the importance of DHA. rpe cells cope with sunlight and oxidative stress, as well as trauma, by using antioxidants like Vitamin E, present in the cells. Dr. Bazan and colleagues...

Blindness can be stopped with drug for acne treatment

...-pigmented epithelium (RPE), a layer of cells near the retina. The accumulation of toxic pigments, or lipofuscin// results in the deterioration of the rpe leading to loss of rods and cones and subsequent central vision loss. Researchers from the University of California, Los Angeles, have now found ...

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RPE in Biological Technology

Assessment of safety and efficacy of human embryonic stem cell therapy

...t early potential hESC applications are the use of rpe for the treatment of age-related macular degenerat...ous system and the eye. In the retina, compromised rpe function can lead to deteriorated vision and photo...in retinal cell physiology and vision restoration. rpe from different hESC lines were tested in the RCS r...

Advanced Cell Technology's Dr. Robert Lanza Makes List of '100 Most Inspiring People in the Life-Sciences Industry'

...esearch may yield to treat indications that have few alternatives." Over the past year, Advanced Cell Technology has made significant progress in its rpe (retinal pigment epithelium) and its HG (hemangioblast) programs to treat degenerative retinal disorders and cardiovascular disease, and expects to fi...
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