...As are easier to slip into cells. In order to specifically target cancer cells, the particles carry a short peptide, called RGD, which points the way: rgd
strongly binds to an integrin, a membrane protein that is anchored to metastasizing tumor cells in much higher amounts than in healthy tissue. The int...
Brown chemists create cancer-detecting nanoparticles
...r the MRI to "hear" the stronger signal and to hone in on the signal's source.
Another important feature of the team's work is discovering that the rgd
peptide coating binds almost seamlessly to the U87MG tumor cell. The team plans to test the particle's ability to bind with other tumor cells in furth...
Novel anticancer strategy moves from laboratory to clinic
...cation more than a decade ago.
"It was a total non-drug: toxic, insoluble and broke down too fast," Dr. Durden says.
Attaching the tag, called a rgd
peptide, makes the inhibitor dissolve easier and last longer in the body. It also lets molecules on blood vessel walls grab the compound and send it i...
RGD in Biological News
RGD in Biological Products
jetPEI-RGD + NaCl sol. from Polyplus Transfection
Description:...elial and endothelial cells-directed transfection reagent : jetPEI-RGD is a rgd
peptide-conjugated polyethylenimine which allows targeted efficient transfe... extracellular matrix proteins. jetPEI-RGD/DNA complexes present many short rgd
peptides on their surface and mimic the integrins natural ligands, hence th...