New, automated tool successfully classifies and relates proteins in unprecedented way
For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a cell.The approach, developed by Carnegie Mellon University, outperformsexisting visual methods to localize proteins inside cells...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine
When the most common adult leukemia in the United States was last reviewed by the New England Journal of Medicine (NEJM) in 1995, it was seen through the eyes of theories that dated back to the 1960s. As such, the journal recently invited three of the world's foremost experts on chronic lymphocytic leukemia (CLL) to write an authoritative update covering the transformation in the scientific commu...Combination therapy boosts effectiveness of telomere-directed cancer cell death
Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...“Nano-scissors?laser shows precise surgical capability
)is quite a challenge; its about 1 mm in length. A research team fromthe University of Texas at Austin developed a method of laser-assistedsurgery to work on these little beasts, being able to section a singleaxon (the "arms" of a neuron) with g...PB3002-S/FACT DeltaRange Precision Balance from Mettler Toledo, Inc.
Description:Accurate, easy-to-use and reliable to provide good weighing for many years that sums up the Classic Balances from METTLER TOLEDO in a single sentence. The robust full metal housing make these balances your reliable partner for everyday use. * Adjustment with internal weights FACT * Adjustment with external weights 2000 g * Sensitivity (temperature Sampling pump drift) 6 ppm/C <...PL1501-S Precision Balance from Mettler Toledo, Inc.
Description:Simple operation and an easy-to-read LCD display characterize our Classic Light balances. * Taring range 0...1510 g...S. cerevisiae Direct Transformation Kit from Wako Chemicals USA, Inc.
Description:This kit is designed for easy transformation of the budding yeast, Saccharoyces sp.. The protocol allows for successful transformation simply by mixing a plasmid DNA and the kit reagents with cultured yeast cells. No complicated steps, such as centrifugation or cell washing, are required. The kit is particularly well suited for high-throughput transformation of a large number of yeast strains gro...S. cerevisiae Direct Transformation Kit from Wako Chemicals USA, Inc.
Description:This kit is designed for easy transformation of the budding yeast, Saccharoyces sp.. The protocol allows for successful transformation simply by mixing a plasmid DNA and the kit reagents with cultured yeast cells. No complicated steps, such as centrifugation or cell washing, are required. The kit is particularly well suited for high-throughput transformation of a large number of yeast strains gro...LX80 Series Precision Stages from Parker Hannifin Corporation
Description:The LX80L is an extension of Parkers MX80 family of positioners, offering longer travel while maintaining a compact cross-section. LX80L bolt hole patterns mimic the MX80 family, allowing users to directly mount MX80 units and all accessory brackets to build multi-axis systems. Velocities to 3 m/s...Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
Danny Q. Hoang Michael Browning Xinping Yang PeterPingerelli Stratagene Cloning Systems, Inc. Stratagene introduces affinity purified antibodies for NMDA receptorsubunits that are useful for studying expression of the NR2A, NR2B and NR2Csubunit proteins...Counting Colonies or Plaques Directly from Images of Agar Plates
Michelle Cayouette Jane Moores Michael Steege AlanOrr Stratagene Cloning Systems, Inc. software version 3.1,researchers have the ability to automatically count bacterial colonies andplaques on agar plates. Researchers can use...Detecting Gastrin-Releasing Peptide Receptor by in situ PCR on Archived Tissue
In situ Adapter for the RoboCycler 40 Temperature Cycler allows rapidamplification of rare mRNA Department of Medicine, University of Illinois at Chicago Figure 1: RoboCycler 40 Temperature Cycler In Situ Adapter Syst...High-Efficiency Site-Directed Mutagenesis of Large Plasmid Vectors
QuikChange XL: a highly versatile kit for site-directed mutagenesis oflarge plasmids Michael Borns Peter Vaillancourt Holly Hogrefe Jeff Braman Stratagene The QuikChange site-directed mutagenesis kit* characteristicallygenerates mutagenesis efficiencies exceeding 80%. We have created a new kit formutagenesis of large plasmid...Recommendations for Treatment of Blood Pressue
The National Heart, Lung, and Blood Institute (NHLBI) and the National High Blood Pressure Education Program (NHBPEP),USA, have come out with recommendations to treat Hypertension.Control of systolic blood pressure is as important as control of Diastolic blood pressure. This is a crucial message for health care providers, patients, and their families. For many years, the importance of low...Amphetamines Help Recovery of Stroke Patients
A new study from Doctors at UT Southwestern in Dallas soon report that amphetamines may speed up the recovery of speech in stroke patients who have lost the function. This study was done on patients who had suffered from ischemic stroke, or a stroke due to loss of blood and oxygen to the brain. Amphetamines were given to 30 stroke patients who lost their ability to spea...Thyroid hormone treatment hastens recovery after cardiac surgery
Thyroid hormone treatment after surgery requiring heart bypass speeds recovery in children undergoing correction of congenital heart defects, according to a clinical trial published in The Lancet. The effects were greatest in the patients who underwent long and difficult surgeries. Following trauma or surgery or during a critical illness, thyroid hormone concentrations plummet. Ma...Cancers of Colon & Rectum linked to Cigarette Smoking
The risks of smoking are well known. Besides causing 160,000 deaths annually from lung, mouth, bladder and other cancers, smoking also increases the risk of death from cancer of the colon or rectum, according to results of a large new study from the American Cancer Society. As many as 12% of all colorectal cancer deaths in the US may be caused by tobacco smoking. "Colorecta...Patient’s perception of health status helps in better recover
We always insist that we should feel healthy to actually live healthy. Doctors in England say that following a coronary bypass surgery; the patient’s attitude helps in an early recovery. To justify this argument the researchers conducted a health survey just before coronary bypass operations and assessed the patient’s own perception of his/her own health status. Following surgery those wh...Specialist Direct Ophthalmoscope
Description:Keeler ophthalmoscopes are individually adjusted for perfect focus where it's needed - in the eye, not on paper. This, along with Keeler's wide angle light beam and infinity focus, ensures that whatever the patient's pupil size, you will see the clearest and largest field of view. Lithium-ion technology provides a longer life battery and fast charge capability. With curved surfaces and subtle pat...Vaccine Can Prevent Cervical Cancer and Precancerous Lesions
LONDON, June 28, 2007--A cervical cancer vaccine has shown 90%efficacy for prevention of cervical cancer and precancerous lesionsassociated with the human papillomavirus (HPV) types targeted bythe vaccine, conclude authors of an Article published early Onlineand in the upcoming issue of The Lancet. HPV types 16 and 18 account for 70% or morecases of cervical cancer worldwi...