A Broad-Spectrum Antibiotic with Activity Against MRSA and Pseudomonas Aeruginosa Would Earn a Higher Patient Share in the U.S. than in Europe for the Treatment of Hospital-Acquired Pneumonia

Merck's Drug Will Remain Decision Resources Gold Standard Through 2017, According to a New Report from Decision Resources WALTHAM, Mass., March 3 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that a b...

The Outbreak of Pseudomonas Aeruginosa In An LA Hospital, Makes 7 Children Sick

White Memorial Medical Center near downtown Los Angeles has shut its neonatal and pediatric intensive care units to new admissions after identifying an outbreak of a potentially// fatal bacterium Pseudomonas aeruginosa. Seven children are supposed to be infected with the virulent bacterium, includi...

Prototype, 7-foot-tall sanitizer automates disinfection of hard-to-clean hospital equipment

...wo days, including growth of potentially dangerous gram-positive bacteria, such as MRSA and VRE, as well as gram-negative type bacteria, most notably, pseudomonas aeruginosa, and Acinetobacter baumannii, plus some types of fungi. "Our study results with the prototype offer strong evidence that more can be do...

AlphaRx Presents Positive Preclinical Data on Zysolin(TM) Inhalable Nanoparticles at Controlled Release Society Annual Meeting

... results which demonstrated that an inhaled tobramycin nanoparticle (Zysolin(TM)) formulation was a more effective treatment in animal models of acute pseudomonas aeruginosa pneumonia when compared to inhaled and injected conventional tobramycin solutions. The data was presented recently in an oral podium sessio...

Independent Laboratory Testing Shows BioNeutral's Hospital Grade Ygiene(TM) Eliminates Aspergillus Niger (Black Mold) Spores

...us and difficult to kill antibiotic resistant forms including, Methicillan Resistant Staphylococcus Aureus often referred to as "MRSA", drug resistant pseudomonas Aeruginosa and the very difficult to eradicate pan resistant Klebsiella Pneumoniae. Obviously the new strain of H1N1 virus (Swine Flu) will not prese...

European researchers look for new ways to fight multi-drug-resistant bacterial infections

...last-resort" antibiotic colistin to treat infections caused by the bacteria pseudomonas aeruginosa or Acinetobacter baumannii. At the same time, the lack of econom... division mechanisms of four of the most resistant gram-negative bacteria - pseudomonas aeruginosa, Helicobacter pylori, Acinetobacter baumannii and Escherichia co...

Intercell Supports the Japanese Encephalitis Vaccination Recommendations of CDC's Advisory Committee on Immunization Practices

...rck & Co., Inc., Wyeth, and Sanofi Pasteur. The Company's pipeline includes a Travelers' Diarrhea Vaccine Patch (Phase III in preparation), a pseudomonas vaccine candidate (Phase II), a Vaccine Enhancement Patch to prevent Pandemic Influenza in combination with an injected vaccine (Phase II), a vaccine ...

Derma Sciences Announces First Commercial Sales of BIOGUARD(TM) Barrier Dressings

...phylococcus aureus 7.10 (>99.99999%) Escherichia coliform 7.10 (>99.99999%) pseudomonas aeruginosa 7.22 (>99.99999%) Corynebacterium xerosis 5.68 (>99.999%) Micrococ...

Zysolin(TM) Pre-clinical Data Supports Once-a-day Dosing in Humans

...n inhaled Tobramycin nanoparticle formulation utilizing the company's proprietary drug delivery platform, and intended for the adjunctive treatment of pseudomonas Aeruginosa Pneumonia in intubated and mechanically-ventilated patients (VAP). In a recent pivotal animal PK (pharmacokinetic) study, Zysolin(TM) del...

Medizone Announces That Its AsepticSure(TM) Development Program is Reaching Objectives on Two Fronts

... SAN FRANCISCO, June 15 /PRNewswire-FirstCall/ -- Early results from the second series of trials have demonstrated a 5 log reduction (99.999%) in pseudomonas aeruginousa and a 4.4 log reduction (99.994%) in Methicillin Resistant Staph Aureus (MRSA). Both of these pathogens are of major concern to medical tr...

Pseudomonas in Medical Technology

Transave Announces Positive Phase II Results for Once-Daily Arikace(TM) in the Treatment of Cystic Fibrosis Patients Who Have Pseudomonas Lung Infections

Data Presented at the European Cystic Fibrosis Society Conference MONMOUTH JUNCTION, N.J., June 13 /PRNewswire/ -- Transave, Inc., today reported positive results from a Phase II clinical trial on its lead investigational drug, Arikace(TM) (liposomal amikacin for inhalation). The compound i...

Cystic Fibrosis - Liposomal Tobramycin Receives Second Orphan Drug Designation Within Weeks

...ibrosis. Only three months ago, the FDA granted Fluidosomes(TM)-tobramycin orphan drug designation for the treatment of pulmonary infections caused by pseudomonas aeruginosa. The newly granted second designation relates to pulmonary infections caused by Burkholderia cepacia (B. cepacia) pathogens. Despite...

Calixa Therapeutics Announces Initiation of Phase 2 Clinical Trial of Its Antibiotic, CXA-101, in Patients with Complicated Urinary Tract Infections

...sporin antibiotic with excellent in vitro and in vivo activity against pseudomonas aeruginosa , including drug resistant isolates. Calixa is investigating CX...nt activity against increasingly resistant gram-negative pathogens such as pseudomonas aeruginosa ," said Dr. Ian Friedland, chief medical officer of Calixa. "W...

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

...atent Covering ARIKACE for Once-Daily Treatment of pseudomonas Lung Infections MONMOUTH JUNCTION, N.J., June...for inhalation), an antibiotic that aims to treat pseudomonas lung infections in cystic fibrosis (CF) and non-C... Phase II clinical trial in U.S. CF patients with pseudomonas lung infections and a preclinical study. The com...

Intercell AG Announces First Subject Enrolled in a Phase II Trial for the Further Development of Its Investigational Vaccine Enhancement Patch to Improve Pandemic Influenza Prevention in Collaboration With U.S. Department of Health and Human Services (HHS

...is, Merck & Co., Inc., Wyeth, and Sanofi Pasteur. The Company's pipeline includes a Travelers' Diarrhea Vaccine Patch (Phase II concluded), a pseudomonas vaccine candidate (Phase II), a Vaccine Enhancement Patch to prevent Pandemic Influenza in combination with an injected vaccine, a vaccine program for...

Cystic Fibrosis - Orphan Drug Designation for Innovative Treatment Against Lung Infections by Axentis Pharma AG

...tory tract in patients with cystic fibrosis. The orphan drug designation is granted with respect to treatment of pulmonary infections caused by pseudomonas aeruginosa, a bacterium that is one of the most common causes of infections of the respiratory tract in patients with cystic fibrosis. Axentis Pharmas...

Intercell Starts a Phase I Clinical Trial for a New Streptococcus pneumoniae Vaccine

...ing Novartis, Merck & Co., Inc., Wyeth, and Sanofi Pasteur. The Company's pipeline includes a Travelers' Diarrhea Vaccine Patch (Phase II), a pseudomonas vaccine candidate (Phase II), a Vaccine Enhancement Patch with infected Pandemic Influenza vaccines (one shot plus patch, Phase I), a Phase II vaccine...

Calixa Therapeutics Announces Positive Phase 1 Results for CXA-101, a Novel Intravenous Cephalosporin Antibiotic with Excellent Anti-Pseudomonal Activity

...ther clinical development of this compound. " pseudomonas aeruginosa is usually less susceptible to commonl...07. CXA-101's potent in vitro activity against pseudomonas aeruginosa has the potential to address the unmet... is highly active against multiple drug-resistant pseudomonas aeruginosa, including many strains resistant to c...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

...sing. Encouraging signs of drug activity were also observed in this trial. New preclinical results demonstrate that MP-376 has potent activity against pseudomonas aeruginosa (P. aeruginosa) infection under a wide array of conditions, avoids resistance development when used at high concentrations achievable with ...

Favourable Six Months Follow-Up Results From Intercell's Phase II Therapeutic Hepatitis C Program

.... Approval in those markets is anticipated during the second half of 2008. The Company's development pipeline includes Phase II vaccine programs for pseudomonas (in-house development) and S. aureus, which is being developed with Merck & Co. Inc. The Company's novel Travelers' Diarrhea vaccine patch will enter ...

Pseudomonas in Medical Products

X-TERIL Skin Care Antimicrobial Spray

Features:... In less than 30 seconds, destroys over 99% of bacteria, virus, fungi and spores on the skin, including staphylococcus, salmonella, pseudomonas and the HIV virus. Kills germs promptly in minor burns, cuts and scrapes, providing residual antimicrobial action for hours. pH balanced, no ri...
Company:BersaChem, Inc.

Pseudomonas in Medical Dictionary

Skin infection

...'s foot, jock itch, ringworm, and yeast infections . The infection is usually caused by bacteria that normally live on the skin , such ... pseudomonas aeruginosa skin ; soft tissue; and bone infections ... Candidiasis is by far the most common type of yeast infections in human skin . ... ...

Pseudomonas in Biological News

A matter of density, not quantity

... in particular are often caused by bacteria called pseudomonas aeruginosa. Once they reach a certain density, colonies of pseudomonas aeruginosa produce virulence factors and can enter...er), each containing only one or very few cells of pseudomonas aeruginosa. Even with these extremely low cell cou...

Plant microbe shares features with drug-resistant pathogen

... biotech applications designed to increase plant growth. "The work in our lab is presently concentrating on two other plant-growth promoting bacteria, pseudomonas putida W619 and Enterobacter sp. 638, neither of which contain broad spectrum antibiotic resistance or virulence factors that would allow them to beha...

Two-pronged model could help foil tough cystic fibrosis infections

...patients are plagued by infections of the bacteria pseudomonas aeruginosa. Their mucous-clogged lungs are fertil...crobes, can control, but not efficiently eliminate pseudomonas established on CF airway cells. Last year, the ...load can enhance the ability of tobramycin against pseudomonas infection. "The beauty is that we are mixing ...

Sugar on bacteria surface serves as base for a web of resistance

...gs. In the case of the bacterium being studied, pseudomonas aeruginosa, the results of biofilm development can...agues had singled out Psl as the likely culprit in pseudomonas biofilm creation a few years ago, but weren't cert...NA, with its double-helix shape, exists within the pseudomonas biofilm, offering additional web-like structural s...

Research could lead to new non-antibiotic drugs to counter hospital infections

...Science . The findings could lead to new drugs that would disarm the increasingly antibiotic-resistant pathogen rather than attempting to kill it. pseudomonas aeruginosa is one of the most serious hospital-acquired pathogens. A common cause of lung infections, it is also found in the intestinal tract of 20 ...

University researchers to develop coatings that kill superbugs

...rium survive? "From this knowledge we can stay one step ahead of evolution in the fight against pathogenic bacteria and infections such as MRSA and pseudomonas aeruginosa." Early work by the University of Bath team has made new compounds containing zinc, copper and silver which have been effective against ...

No hiding place for infecting bacteria

...al of Medical Microbiology , Dr Quinn Parks and colleagues describe how they used enzymes against products of the body's own defence cells to prevent pseudomonas aeruginosa bacteria from building a protective biofilm which enables them to avoid both the body's immune mechanisms and antibiotics. When the bod...

Fowl soil additive breaks down crude oil

... analysis of their samples and identified 21 different microbial species known as aerobic heterotrophs. The team explains that Bacillus species and pseudomonas aeruginosa were the best oil-munching microbes but of the 21 isolates 12 were capable of metabolizing components of crude oil. Other microbes include...

Special issue of BMC Microbiology spotlights standardized language for describing microbes

...and differences for a specific type of effector protein in very different bacterial organisms is shown by taking a close-up look at the plant pathogen pseudomonas syringae pv tomato DC3000 and the animal pathogen Escherichia coli strains. Many plant pathogens that draw their nutrition from living tissue have ...

Winter brings flu, summer brings bacterial infections

...ntrol and Hospital Epidemiology, a professional journal. The study examined infections caused by several gram-negative bacteria, including E. coli, pseudomonas aeruginosa, E. cloacae, and Acinetobacter baumannii. The greatest increases in infection due to higher temperatures were found with P. aeruginosa, a c...

Pseudomonas in Biological Technology

Ondine Announces Publication of Positive Results from Pseudomonas aeruginosa Eradication Study

VANCOUVER, Aug. 7 /PRNewswire-FirstCall/ - Ondine Biopharma Corporation (TSX: OBP; AIM: OBP), a medical technology company developing photodisinfection-based products, today announced that the results of a study using the Company's platform Photodisinfection technology to eliminate Pseudomonas...

Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria

...it in treating cystic fibrosis (CF) patients with pseudomonas lung infections is encouraging as we tackle this ...rom a clinical trial in European CF patients with pseudomonas lung infections. The company also previously ann...t of non-CF patients who have bronchiectasis with pseudomonas lung infections and a second trial in U.S. CF pat...

Intercell Announces European Approval of New Vaccine, IXIARO(R), to Prevent Japanese Encephalitis

...yeth, Sanofi Pasteur, Kyowa Hakko Kirin and the Statens Serum Institut. The Company's development pipeline includes Phase II vaccine programs for pseudomonas (in-house development) and S. aureus , which is being developed with Merck & Co. Inc. The Company's novel Travelers' Diarrhea vaccine patch will ...

Intercell to Host Conference Call and Webcast Today on FDA Approval of IXIARO(R) Japanese Encephalitis Vaccine

...yeth, Sanofi Pasteur, Kyowa Hakko Kirin and the Statens Serum Institut. The Company's development pipeline includes Phase II vaccine programs for pseudomonas (in-house development) and S. aureus, which is being developed with Merck & Co. Inc. The Company's novel Travelers' Diarrhea vaccine patch will en...

Intercell Announces FDA Approval of IXIARO(R), a Novel Vaccine to Prevent Japanese Encephalitis

...yeth, Sanofi Pasteur, Kyowa Hakko Kirin and the Statens Serum Institut. The Company's development pipeline includes Phase II vaccine programs for pseudomonas (in-house development) and S. aureus, which is being developed with Merck & Co. Inc. The Company's novel Travelers' Diarrhea vaccine patch will en...

Lakewood-Amedex, Inc. Appoints William J. Robison, Former Executive Vice President of Pfizer, as Board Member

...effective against a wide range of bacteria, encompassing antibiotic resistant strains including methicillin-resistant Staphylococcus aureus (MRSA), pseudomonas and others, and patents covering certain proprietary products targeting pandemic viral infections including, Epstein Barr Virus (EBV), human and avia...

AdvanDx Receives FDA 510(k) Clearance for E. coli/P. aeruginosa PNA FISH(R)

...Newswire/ -- AdvanDx today announced it received FDA 510(k) clearance for E. coli / P. aeruginosa PNA FISH(R) to identify Escherichia coli and/or pseudomonas aeruginosa directly from positive blood cultures. E. coli / P. aeruginosa PNA FISH is the first-ever test for identifying E. coli and P. aerugin...

Transave, Inc. Secures $12.5 Million in New Financing

... our Arikace Phase II program for the treatment of pseudomonas infections in cystic fibrosis patients," said Tim ...ase II trial to evaluate the compound for treating pseudomonas infections in patients with non-cystic fibrosis-re...current respiratory infections, which often have a pseudomonas component. Kristen Kosofsky, managing director o...

Ondine Biopharma Announces Second Quarter 2008 Financial Results

...nflammation of the outer ear and ear canal often caused by bacteria such as pseudomonas aeruginosa and Staphylococcus aureus. Moderate Otitis Externa can result in...the recently published article titled "In Vitro Photodynamic Eradication of pseudomonas aeruginosa in Planktonic and Biofilm Culture", Ondine researchers conclusiv...

Iomai, Intercell Chief Scientific Officers to Speak on Future of Vaccines at BIO International Convention Today

... The Company's broad development pipeline includes a partnered S. aureus vaccine in Phase II, a therapeutic vaccine against Hepatitis C in Phase II, a pseudomonas vaccine in Phase II, a partnered Tuberculosis vaccine (Phase I/II), and five products focused on infectious diseases in preclinical development. I...

Pseudomonas in Biological Products

Gelzyme enzyme from Invitrogen

Description:... Gelzyme is an agarose-digesting enzyme isolated from pseudomonas atlantica. Gelzyme enzyme cleaves simple carbohydrate bonds in agarose producing carbohydrate molecules that can no longer gel. The remaining carbohyd...
Company:Invitrogen

beta-Agarase from USB Corp.

Description:... Source: pseudomonas atlantica Description: Beta-Agarase is useful in recovering DNA and RNA fragments from low-melting-temperature agarose. Beta-Agarase digests the agaro...
Company:USB Corp.

Pseudomonas in Biological Dictionary

RecA protein

... a nucleoprotein filament whose ... However, RecA protein is also a dATPase; dATP supports RecA -RFP nucleoprotein ... The RecA protein of pseudomonas aeruginosa (RecAPa) exhibits a more robust ... RecA protein , a central enzyme of homologous recombination and recombinational ... ...

Phage

...... The nematode acts as a vector for the phage , facilitating the spread of its own competitor. ... We employed the segmented RNA phage 6 and pseudomonas syringae pv. ... Home > Technical Reference > Protein Tools > FAQs For Phage Display Peptide Libraries ... What are the advantages of p...

Bioaugmentation

... ... Cell bioaugmentation was further demonstrated when Comamonas testosteroni was ... ... nitrogen source) and/or bioaugmentation (addition of pseudomonas aeruginosa ... improved bioremedation of HMW PAHs using biostimulation and/or Bioaugmentation . ... Bacteria are a skilled workforce in the task o...