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Proteinase in Medical News

CIDP Treated With Plasma-Derived Therapy

... with hemophilia, immune globulin intravenous used to prevent infections in people with immune deficiencies and other serious conditions, and alpha 1 proteinase inhibitor used to treat people with alpha 1 antitrypsin deficiency, also known as genetic emphysema. ...

Enzyme and vitamin define the yin and yang of asthma

... HOUSTON (March 29, 2009) The allergen breathed in by a person with asthma triggers a proteinase or enzyme called MMP7 that activates a cascade of events to prompt an allergic reaction, said a consortium of researchers led by Baylor College of Med...

Kawasaki Disease Treated with Plasma-Derived Therapy

... with hemophilia, immune globulin intravenous used to prevent infections in people with immune deficiencies and other serious conditions, and alpha 1 proteinase inhibitor used to treat people with alpha 1 antitrypsin deficiency, also known as genetic emphysema. ...

Do You Have Genetic COPD?

... Melissa urged her family members and daughter to be tested. Not surprisingly, many relatives received the same diagnosis. Medications called alpha-1 proteinase inhibitors are available for the treatment of AATD, and replace the missing protein that helps the lungs function properly. "A simple blood te...

PPTA Launches New Educational Website on Donating Plasma

...e with hemophilia, intravenous immune globulin used to prevent infections in people with immune deficiencies and other serious conditions, and alpha-1 proteinase inhibitor used to treat people with alpha-1-antitrypsin deficiency, also known as genetic emphysema. ...

JCI table of contents: June 20, 2008

...croorganisms. The authors therefore suggest that these data provide rationale for considering inhibitors of NSPs as anti-inflammatory drugs. TITLE: proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin AUTHOR CONTACT: Kai Kessenbrock Max-Planck-In...

ASPB engages Latin America colleagues at Annual Meeting in Merida, Mexico June 22-25

... of genomics tools - case study: tomato Solanaceae. Felipe Cruz, Mexico Synthesis and transfer to the stigmatic surface of NaStEP, a vacuolar Kunitz proteinase inhibitor homolog and its role in pollen rejection in Nicotiana. Esther Van Der Knaap, Ohio State University, USA - Underlying mechanisms of diversit...

Melissa Biggs, Fashion Designer and Former Baywatch Actress, Teams with CSL Behring to Raise Awareness of Alpha-1 Antitrypsin Deficiency, a Commonly Misdiagnosed Respiratory Disease

...lf of CSL Behring, maker of Zemaira(R), Alpha-1 proteinase Inhibitor (Human) Augmentation ...h CSL Behring's Zemaira, a next-generation Alpha-1 proteinase inhibitor proven to raise and maintain levels of a...ira Zemaira is a highly-purified form of Alpha-1 proteinase Inhibitor (A1-PI), the critical, naturally occurri...

Elevated Carbondioxide may Have Negative Impact on Ecosystem

...hey studied soybeans grown in traditional field conditions but with additional exposure to ambient CO2. The results showed that the amount of cysteine proteinase inhibitors (CystPls) expressed in the genes decreased when soybeans were exposed to elevated CO2. CystPls is naturally produced by soybeans wh...

Estrogen Linked to Immune Surveillance in Breast Cancer

...e tumor cell. The research team found that when estrogen binds to an estrogen receptor the complex promotes production of a granzyme inhibitor, proteinase inhibitor 9 (PI-9). The inhibitor binds the granzyme, preventing it from initiating the molecular cascade that kills tumor cells. “It wasn’t kno...
Proteinase in Medical Products

Anti-PR3 EIA Auto-Immune Markers 013-PR3-96 Proteinase

Description: Anti-PR3 EIA Auto-Immune Markers 013-PR3-96 Proteinase...
Company:ALPCO Diagnostics

Anti-PR3 EIA Auto-Immune Markers 013-PR3-48 Proteinase

Description: Anti-PR3 EIA Auto-Immune Markers 013-PR3-48 Proteinase...
Company:ALPCO Diagnostics

Anti-GBM Antibodies ELISA

Description:... This ELISA test is used for the detection and semi-quantitation of lgG antibobies to proteinase 3(pr3) in human sera, as an aid to the diagnosis of wegener s granulomatosis....
Company:TheraTest Laboratories

AutoIncubator 96

Description:... 16 of AutoGen's tube units to prepare 96 samples at a time. This new system is most appropriate for bacterial cultures and enzyme reactions, such as proteinase K digestion. Now you can further simplify your DNA extraction process by preparing your samples with our AutoIncubator 96 and then placing our 6-hole...
Company:AutoGen Inc

Anti-Proteinase 3-ANCA

Description:... The ELISA test is used for detection and semi quantitation of igG antibodies to proteinase 3(PR3) in human sera, as an aid to the diagnosis is of Wegener's granulomatosis....
Company:TheraTest Laboratories

Anti-PR 3 - ELISA (C-ANCA, ACPA)

Description:... Enzyme immunoassay for detection and quantification of proteinase 3 autoantibodies in serum.no subjective criteria as in indirect immunofluorescence.Follow-up control of disease activity by quantitative results.Paral...
Company:DLD Diagnostika GmbH

Anti-MPO ANCA EIA Auto-Immune Markers 013-MPO-48 Myeloperoxidase

Description:...tigen in the azurophil granules of the cytoplasm of human neutrophils (8) and later that the principal antigen was a 29kD serine protease identical to proteinase 3 or myeloblastin (9,10,11). When detected by antigen specific assays these autoantibodies are termed 29kD-ANCA or PR3-ANCA. The other subclass o...
Company:ALPCO Diagnostics
Proteinase in Biological News

Mate choice in plants

...ave recently identified and characterized another factor, Stigma Expressed Protein (NaStEP) in N. alata. Sequencing revealed that it is homologous to proteinase inhibitors, enzymes that prevent protein degradation, and that it contains a sequence that targets it to the vacuoles of unpollinated stigmas. If inc...
Proteinase in Biological Technology

Halozyme Therapeutics Reports 2008 Second Quarter Financial Results

...e European Society for Dermatological Research and Japanese Society for Investigative Dermatology. HTI-501, a new recombinant human lysosomal proteinase that could provide an effective dermatologic treatment by targeting and degrading the fibrous components of the extracellular matrix in a ...

Genomic Analysis of Formalin-Fixed Paraffin Embedded (FFPE) Tissues through the use of Whole Genome Amplification (WGA)

...Cat. No. WGA5 ), designed for fresh, frozen or fixed tissues, includes reagents to effect a very gentle extraction. The lysis uses a combination of proteinase K and lytic detergent, and draws from the experience gained in the development of the Sigma Extract-N-Amp ™ reagent line. Efficient, gentle...

TissueRuptor System

...(Figure 3). Significant time savings are gained when using the QIAamp DNA Mini Kit for DNA purification as the lysis step with proteinase K can be reduced to just 1 hour. Purified DNA performs well in PCR (Figure 4). High...

DNA purification from pig ears to bird blood using proven DNeasy Technology

...its provide fast and easy silica-based DNA purification in convenient spin-column and 96-well-plate formats. Most samples can be directly lysed with proteinase K, eliminating the need for mechanical disruption and reducing hands-on time. Optimized protocols for specific sample types provide reproducible pur...

GenomiPhi amplification of FFPE tissue DNA for array CGH

...The detailed protocol is given below. DNA was quantitated using PicoGreen dsDNA quantitation reagent.

1. Add 2 µl of 10 mg/ml proteinase K to each tube (final concentration 200 µg/ml).

2. Incubate at 55 °C for 3 h. Agitate gently every hour.

Analysis of Bacterial Assemblage Genetic Diversity in Environmental Samples Using the DCode System

...taining 15 g/ml of freshly added lysozyme (Sigma Chemical, St. Louis, MO) and heated at 37 C to aid in dissolution. Two mg/ml of proteinase K (Sigma Chemical, St. Louis, MO.) was added to the samples followed by a 30 minute incubation at 37 C. Next, 10 ml of lysis buffer ...

Transgenic Zebrafish by Electroporation

... and development appears morphologically normal. Six days after spawning a random sample of fry are sacrificed and digested with proteinase K overnight at room temperature. The proteins are removed by phenol/chloroform extractions and the genomic DNA is precipitated f...

Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae

...g 1% sarkosyl (Na salt of N-lauroylsarcosine, Sigma) and 50 g/ml proteinase K (Boehringer Mannheim), and incubated overnight at 50 C. The ne...se E (Sigma P 6911) at 37 C for 2 to 24 hours instead of 50 g/ml proteinase K overnight at 50 C; stationary instead of log phase cultures; u...

PFGE Analysis of Chromosomal DNA From a Single Hair Root

...solidification, the block was placed in a NDS lysis solution consisting of 10 mM Tris, 0.5 mM EDTA, 1% sarcosyl, pH 9.5, 1 mg/ml proteinase K, and 25 mM dithiothreitol. Blocks were incubated 24 hours at 50 C, with a fresh change of lysis buffer after 24 hours. Blocks ...

Quantitative Analysis of Protein-DNA Associations in Vivo Using Real-Time PCR, Rev A

... immunoprecipitated using a specific antibody. The coimmunoprecipitated DNA fragments are then liberated from the protein by treatment with proteinase K, and the DNA fragments are identified by Southern blotting or PCR (Kuo and Allis 1999). More recently, studies have establishe...
Proteinase in Biological Dictionary

Morphogenesis

...n (surface contact) is the most important in morphogenesis . ... ECM-receptor control of branching morphogenesis . Relation between ECM-degrading proteinase activity and branching morphogenesis ... II. Colony morphogenesis and formation of the extracellular matrix. Dev Biol. ... Morphogenesis in V...
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