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Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

The complex and life-sustaining series of steps by which hematopoietic stem cells (HSC) give rise to all of the body's red and white blood cells and platelets has now been discovered to depend in large part on a single protein called Mcl-1. This finding, from an investigator at St. Jude Children's Research Hospital, is published in the February 18 issue of Science. Mcl-1 blocks the biochem...

Whole genome promoter mapping - Human Genome Project v2.0?

Investigators from the University California, San Diego (UCSD) Branch of the Ludwig Institute for Cancer Research (LICR) and NimbleGen Systems have developed an efficient method to identify thousands of regulatory sequences in the human genome, according to a study published today in Nature. Genes are defined by their ability to generate a functional product. Thus the 'promoter' - a DNA se...

New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids

The immune system is a complex and powerful weapon that provides protection against bacteria and viruses that, if left unchecked, would wreak havoc throughout the human body. The ability of the immune system to recognize the body's own tissues is essential, but sometimes the immune system loses the ability to distinguish "self" from potentially harmful invaders. This can lead to autoimmune diseas...

Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors

Prostate cancer is a cruel disease. Left untreated, prostate cancer cells often metastasize, or spread, to bone where they form fracture-prone tumors that are extremely painful. More than 80 percent of men who die from prostate cancer die with metastatic disease in their bones. But scientists know very little about how migrating prostate cancer cells set up housekeeping in bone tissue and...

Islands in the Genome Promote Speciation

Have you ever wondered how the myriad insect forms—beetles, flies, dragonflies, mosquitoes, grasshoppers, ants, wasps, bees, and countless others—evolved? Insects make up 75% of all species known. The large number of insect species is probably a result of a combination of one or more factors: a high rate of formation of new species, or speciation, an ability to adapt to new environments an...

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Hendee promoted to president of MCW Research Foundation; Gutterman steps up

T. Michael Bolger, the college's president and CEO, made the announcement on Friday. "Over the past 14 years, Bill Hendee has provided outstanding leadership...

Merge Healthcare promotes Bowers to president

Bowers, who had been serving as the company's senior vice president of strategic business initiati...

UWM research dean promotes building boom

UW-Madison is an institution he deeply admires, but he also believes his own institution, the University of Wisconsin-Milwaukee, has untapped potential as a vehicle for technology transfer that can spark an economic tran...

Satellite radio can promote your national brand

Satellite radio is nationwide and provides a format for every listener and for every advertiser. A satellite radio campaign can be more cost effective to produce, air and manage than a national TV or local AM/F...

Republicans propose sweeping changes to promote investment

A $130 million package of legislative incentives proposed recently by state Republicans is designed to build on efforts to transform Wisconsins economy into a knowledge-based, innovation economy. The package of 20 bills, dubbed Invest Wisconsin, seeks to encourage the creation of high-technology businesses, ands is part of a three- to four-year campaign designed to deliver tax relief, regulatory...

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New Cost Effective Approach To Promote Sun Protection

Based on findings of a recent study researchers say, photos showing hidden sun damage and information on sunless tanning was // effective in helping encourage safe sun behavior in a small group of college students . Researchers showed a sample of 146 college student volunteers an ultraviolet facial photograph revealing hidden sun damage along with a videotape describing the causes and co...

Medical community worried that new curriculum will 'Promote Quackery'

Leading medical bodies in India have criticized the recent announcement of health minister to change the undergraduate medical curriculum. Mr.Vinay Agarwal, Secretary of Indian medical Association // that has over 150,000 doctors as members said: "The idea of adding ayurveda, unani and homoeopathy subjects in the already over-crowded medical curriculum is not going to help anybody,"...

Breast milk promotes cavity formation in babies

A new study appearing in the October issue of the journal Pediatrics says that the cavity forming potential of breast milk is more than that of Cow's milk. Dr. Ruth A. Lawrence of the University of Rochester // in New York and her colleague Dr. William H. Bowen used rats to demonstrate that breast milk had a potential to cause tooth decay faster than cow's milk. Baby mice did develop...

Identification Of Gene Sequence To Promote Growth Of New Arteries

A Research headed by the vascular surgeon Rajabrata Sarkar, MD, PhD, at the San Francisco VA Medical Center has unraveled the genetic mechanism that helps in the growth of new arteries // . He demonstrated in mice that the MMP2 gene is the key factor for the development of new arteries especially when there is blockage in the femoral (leg) artery. As a novel approach the team has analyz...

Indian Government To Promote Better Sanitation

The Indian Government has apportioned an amount of Rs 0.5 million towards a new public-private initiative for providing better community toilets across the country. Places like hospitals, market places, //schools, railway stations, bus stands, and slums will be targeted by the sanitation initiative. The Rs. 1.1 million project has been set up in partnership with the district administration, H...

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Anadys Reports Preclinical Data Showing ANA773 Promotes Anti-Tumor Activity of Natural Killer Cells

Poster Presentation on April 17, 2007 at AACR SAN DIEGO, April 17 /PRNewswire-FirstCall/ -- AnadysPharmaceuticals, Inc. presented data from an in vitro study showingthat the active metabolite of ANA773 promotes natural killer (NK)cell-mediated anti-tumor response by inducing cytokine secretion,cytolysis of tumor cells and enhanced antibody-dependent cellularcytotoxicity (ADCC), during a p...