prolongs

New drug candidate prolongs the lives of pancreatic cancer patients

Every year, 42,000 Americans are diagnosed with pancreatic cancer. Few live very long, and less than 5% are still alive five years after diagnosis. There's new hope, though, from the lab of Prof. Yoel Kloog, dean of Tel Aviv University's Faculty of Life Sciences. His drug compound Salirasib has...

Prostate cancer immunotherapy significantly prolongs survival in men with advanced prostate cancer

CHICAGO, ILSipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago. These data from the Phase 3 Immunotherapy for Pro...

High-flux hemodialysis prolongs survival in many patients with CKD

High-flux hemodialysis (which removes large toxins) reduces the risk of premature death in many patients with chronic kidney disease (CKD), according to a study appearing in the March 2009 issue of the Journal of the American Society Nephrology (JASN). The results suggest that this procedure cou...

Higher Chemo Drug Dose Prolongs Lives of Leukemia Patients

Side effects similar to those seen with standard dose of daunorubicin, study shows THURSDAY, Dec. 4 (HealthDay News) -- A high dose of the chemotherapy drug daunorubicin prolonged survival for patients with previously untreated acute myeloid leukemia (AML), preliminary results of a stu...

Radiation therapy prolongs life in men with recurrent prostate cancer

Men whose tumors recur after prostate cancer surgery are three times more likely to survive their disease long term if they undergo radiotherapy within two years of the recurrence. Surprisingly, survival benefits were best in men whose new tumors were growing fastest, according to results of a "lo...

Golf prolongs life

[PRESS RELEASE, 30 May 2008] Golf can be a good investment for the health, according to a new study from the Swedish medical university Karolinska Institutet. The death rate for golfers is 40 per cent lower than for other people of the same sex, age and socioeconomic status, which correspond to a ...

Treating oft ignored non-cancer health issues after cancer diagnosis prolongs survival

INDIANAPOLIS Receiving treatment for non-cancer health issues while being treated by specialists for cancer improves cancer survival rates according to a study published in the December 20 issue of the Journal of Clinical Oncology. The study, by researchers from the Indiana University School o...

Thalidomide Added to Standard Therapy Prolongs Overall Survival in Newly Diagnosed Multiple Myeloma Patients Over Age 75

- Data Demonstrate 17.6 Month Overall Survival Advantage in Elderly Myeloma Patients when Thalidomide Is Added to Standard Therapy - Data Presented at the 49th American Society of Hematology Meeting ATLANTA, Dec. 9 /PRNewswire-FirstCall/ -- Pharmion Corporation (Nasdaq: PHRM) today anno...

New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas

Barcelona, Spain: Childhood brainstem gliomas (BSGs) are rare but can be very difficult to treat successfully and they tend to have poor survival rates. However, a team of Spanish researchers have found that a chemotherapy regimen of irinotecan and cisplatin (I/C) produced rapid clinical responses...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

...y to degarelix or to any of the product components. FIRMAGON is not indicated in women or pediatric patients. Long-term androgen deprivation therapy prolongs the QT interval. Physicians should consider whether the benefits of androgen deprivation therapy outweigh the potential risks in patients with congen...

prolongs in Medical Technology

Prostate Cancer Immunotherapy Significantly Prolongs Survival in Men With Advanced Prostate Cancer

Phase 3 IMPACT Trial Results to be presented during late-breaking session at AUA Annual Scientific Meeting CHICAGO, April 28 /PRNewswire-USNewswire/ -- Sipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be pr...

Data Presented at AUA Demonstrate PROVENGE Significantly Prolongs Survival for Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

- Extended Median Survival by 4.1 Months and Increased 3-Year Survival by 38 Percent Compared to Placebo - - First Active Cellular Immunotherapy for Cancer to Prolong Survival - - Company to Host Webcast at 5:30 pm ET - CHICAGO and SEATTLE, April 28 /PRNewswire-FirstCall/ -- Dendreo...

Treating Depression Prolongs Life for Older People with Diabetes

Also This Month: Lessons Learned from the Avandia Controversy ALEXANDRIA, Va., Nov. 27 /PRNewswire-USNewswire/ -- Depressed, older adults with diabetes live longer when they are treated for depression, according to a study in the December issue of Diabetes Care, which publishes on November...

Newly Published Phase II Study Shows the Investigational Drug Vandetanib Prolongs Progression-Free Survival in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)

- Phase III trials now underway to evaluate vandetanib as second-line NSCLC treatment in combination with docetaxel - WILMINGTON, Del., Sept. 20 /PRNewswire/ -- Results published today in the Journal of Clinical Oncology(1) show that the AstraZeneca investigational once-daily oral ...

Low-Dose Steroid Combined With Lenalidomide Prolongs Survival Compared With High-Dose Steroid for Multiple Myeloma Treatment

WASHINGTON, April 4, 2007-Preliminary results from a large, randomized clinical trial for patients with newly diagnosed multiple myeloma, a cancer typically found in bone marrow, has shown that the use of a low dose of the steroid dexamethasone (Decadron ®), in combination with lenalidomide (Re...

Oncophage Cancer Vaccine Significantly Prolongs Recurrence-Free Survival by 45 Percent in Patients With Intermediate-Risk Kidney Cancer

ANAHEIM, Calif.--(BUSINESS WIRE)--May 21, 2007 - Antigenics Inc. (NASDAQ: AGEN) today announced additional follow-up data on the company's Phase 3 investigational therapeutic cancer vaccine Oncophage(R) (vitespen). The end-of-study results, which reflect an additional 17 months' data collection, sh...

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

...formulation of the antibiotic amikacin, which encloses the drug in nanocapsules of lipid called liposomes. This advanced pulmonary liposome technology prolongs the release of amikacin in the lungs while minimizing systemic exposure. The treatment uses biocompatible lipids endogenous to the lung that are formu...

The Injured Obese Child: Let's Give Him Some Ankle Support

...nt of those observed were obese. According to Dr. Pomerantz, childhood obesity not only puts children at a greater risk for injuries but it also prolongs recovery time. "Though it is not well studied, we suspect that increased force due to increased weight puts undue strain on the ligaments, tendons, mu...

Chronic Ankle Pain May Be More Than Just a Sprain

...plains that tendon injuries to the ankle can be a possible cause for this chronic pain. In some cases, the condition is untreated or overlooked which prolongs the pain and the problem. "When patients injure their ankles, the injury may not seem serious at first," explains Terrence Philbin, DO, lead auth...

Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy

... to degarelix or to any of the product components. Degarelix is not indicated in women or pediatric patients. Long-term androgen deprivation therapy prolongs the QT interval. Physicians should consider whether the benefits of androgen deprivation therapy outweigh the potential risks in patients with congen...

prolongs in Medical Products

Hemaway Tri-Max Detergent

Description:... for Hemaway Tri-Max, even in hard to reach places like box joints and tubing. Concentrated Hemaway Tri-Max greatly reduces the need for scrubbing and prolongs the life of your instruments. Hemaway Tri-Max is strong enough to remove the toughest debris, yet gentle enough to be used everyday....
Company:Instrument Specialists, Inc.

Growth Hormone Binding Protein ELISA Test

Description:...ng unproductive heterodimers with the GH receptor at the cell surface, as opposed to the GH receptor homodimers required for signaling. The GHBP also prolongs the half-life of GH in the circulation by complexing GH and delaying its elimination (2). The biological role of the GHBP is still unclear due partly...
Company:Diagnostic Systems Laboratories, Inc.

AEH-4 Electrohydraulic Lithotripsy System

Features:... Low purchase price, minimal maintenance > Economical Large, clear LED display > Ease of use Automatice probe sensing circuitry > prolongs life of smallest probes, can predict probe end-of-life Regulates and controls power to the probe and shot frequency > Complete user control...
Company:GYRUS ACMI

AEH-4E Electrohydraulic Lithotripsy System

Features:... Low purchase price, minimal maintenance > Economical Large, clear LED display > Ease of use Automatic probe sensing circuitry > prolongs life of smallest probes, can predict probe end-of-life Regulates and controls power to the probe and shot frequency > Complete user control...
Company:GYRUS ACMI

prolongs in Biological News

Many African-Americans have a gene that prolongs life after heart failure

About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions. The genetic variant has an effect that resembl...

Resveratrol prolongs lifespan and delays onset of aging-related traits in a short-lived vertebrate

By studying a particularly short-lived fish species, researchers have been able to show that a natural compound previously shown to extend lifespan in non-vertebrate organisms can also do so in at least one vertebrate species. The findings, reported by Alessandro Cellerino of the Scuola Normale Sup...

Reducing the roadworks

...ilometres of pipes and cables. Up to now, utility companies have needed to dig a series of 'test' holes to find the service they need to work on. This prolongs the road works and increases the risk of damaging other services beneath the road or pavement. The resulting delay to road users, disruption to busin...

LSUHSC research describes function of key protein in cancer spread

...and Rac. However, IQGAP1 does not deactivate Cdc42 and Rac in fact, IQGAP1 prolongs their activated states. The researchers determined the atomic structure of...t are required for even normal rates of deactivation, explaining how IQGAP1 prolongs the activated state of Cdc42. "This knowledge could serve as a guide for...

February 2009 Geology and GSA Today media highlights

...an 5 millimeters. In some of the world's best studied and stratigraphically expanded Cretaceous-Paleogene mass extinction boundary sections, this bias prolongs the recovery period by about seven million years, the duration that lithified rocks persist after unlithified diversities recover to pre-extinction va...

Study may explain exercise-induced fatigue in muscular dystrophies

...ng pathway is turned off by phosphodiesterase (PDE), an enzyme that breaks down cGMP. Viagra, a drug designed to increase blood flow, inhibits PDE and prolongs the existence of the cGMP molecules that promote blood vessel dilation. The researchers showed that Viagra could alleviate fatigue in mice with mis...

A new idea for how anti-aging products delay ripening of fruit and wilting of flowers

...ting ripening and wilting. Furthermore, unlike ethylene, 1-MCP does not inactivate the receptors. As a result, the cells do not break down, which prolongs the freshness of flowers and fruit after harvest, extends their shelf life, reduces waste and, ultimately, benefits producers and consumers. Adm...

T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role

...-deficient mammary glands the knockouts were deficient in growing new blood vessels to the graft. Stunting blood vessel growth restricts tumors and prolongs survivala strategy behind anti-angiogenesis cancer drugs like Avastinso these results were somewhat expected, says Dr. Ranscht. But what surprised us,...

The quest for an effective HIV vaccine presents new possibilities, challenges

... become latently infected remains the goal. In addition, they believe that even a vaccine that does not prevent infection could prove beneficial if it prolongs the disease-free period and possibly even reduces virus transmission. If such a vaccine is shown to be successful and is eventually licensed, it would...

UCLA study uncovers clues for why Graves' disease attacks the eyes

...in-like growth factor 1. Similar to insulin, IGF-1 stimulates cell growth while suppressing normal cell death. The team suspects that this mechanism prolongs the survival of older T-cells, causing a cascade of autoimmune problems that spur the body to attack its own tissue. "We think that the extra rec...

prolongs in Biological Technology

PROVENGE Significantly Prolongs Survival in Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

- Study Meets Primary Endpoint Showing Statistically Significant Improvement in Overall Survival - - First Active Immunotherapy for Cancer to Prolong Survival - - Full Data to be Presented at Plenary Session at Upcoming AUA Annual Meeting - - Company to Host a Conference Call Today ...

Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria

...ormulation of the antibiotic amikacin, which encloses the drug in nanocapsules of lipid called liposomes. This advanced pulmonary liposome technology prolongs the release of amikacin in the lungs while minimizing systemic exposure. The treatment uses biocompatible lipids endogenous to the lung that are form...

REXIN-G Shrinks Metastatic Tumors and Triples Survival Time in Chemotherapy-Resistant Pancreatic Cancer: Analysis of a U.S. Phase I/II Clinical Trial (Proceedings of ASCO GI Symposium 2009)

...overall safety of Rexin-G, and further demonstrates that Rexin-G monotherapy, at these defined dose levels, exhibits profound anti-tumor activity that prolongs both progression-free survival and over-all survival time in pancreatic cancer patients that had previously failed standard chemotherapy. Rexin-...

Human Genome Sciences Announces Initiation of Phase 2b Trial of Albuferon(R) Dosed Monthly in Chronic Hepatitis C

...lation in the body for approximately 19 days. Research has shown that genetic fusion of therapeutic proteins to human albumin decreases clearance and prolongs the half-life of the therapeutic proteins. Albuferon results from the genetic fusion of human albumin and interferon alfa. Albuferon is being de...

Human Genome Sciences Announces Albuferon(R) Meets Primary Endpoint in Phase 3 Trial in Chronic Hepatitis C

...lation in the body for approximately 19 days. Research has shown that genetic fusion of therapeutic proteins to human albumin decreases clearance and prolongs the half-life of the therapeutic proteins. Albuferon results from the genetic fusion of human albumin and interferon alfa. Albuferon is bein...

Transave, Inc. Secures $12.5 Million in New Financing

...is a form of the antibiotic amikacin that is enclosed in nanocapsules of lipid called liposomes. This proprietary next-generation liposomal technology prolongs release of amikacin in the lung while minimizing systemic exposure. The treatment uses biocompatible lipids endogenous to the lung that are formulated...

Video: Higher Initial Dose of Gleevec Achieved Better Early Responses than Standard Dose for Patients with Chronic Myeloid Leukemia

...RNING: QT PROLONGATION AND SUDDEN DEATHS Tasigna prolongs the QT interval. Sudden deaths have been reported ...ily or dose reduction. QT prolongation Tasigna prolongs the QT interval. Correct hypokalemia or hypomagnes...e, patients who require treatment with a drug that prolongs QT or strongly inhibits CYP3A4 should be closely m...

Kosan Presents Preclinical Data on Novel Third-Generation Hsp90 Inhibitors at AACR

...484 demonstrated almost complete regression of very large (1000 mm3) AML xenografts when dosed on an infrequent (twice a week) schedule. KOS-2484 also prolongs survival in a mouse orthotopic model of AML. These findings underscore that KOS-2484, Kosan's lead non-benzoquinone ansamycin Hsp90 inhibitor, has sig...

Transave, Inc. Raises $35 Million Through Series D Convertible Preferred Stock Financing

...is a form of the antibiotic amikacin that is enclosed in nanocapsules of lipid called liposomes. This proprietary next-generation liposomal technology prolongs release of amikacin in the lung while minimizing systemic exposure. The treatment uses biocompatible lipids endogenous to the lung that are formulated...

Study Confirms Anti-Infective ARIKACE(TM) Effectively Penetrates Mucus and Biofilm, and Kills Pseudomonas, a Bacteria Plaguing Cystic Fibrosis Patients

...is a form of the antibiotic amikacin that is enclosed in nanocapsules of lipid called liposomes. This proprietary next-generation liposomal technology prolongs release of amikacin in the lung while minimizing systemic exposure. The treatment uses biocompatible lipids endogenous to the lung that are formulated...