Probe

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

New keys to understanding the evolution of life on Earth may be found in the microbes and minerals vented from below the ocean floor, say scientists at the University of California, Santa Barbara. The UCSB scientists are making new contributions to this field of inquiry in their studies of seafloor hydrothermal fluid discharge into the Earth's oceans, which has been occurring ever since t...

Nano-Probes Allow an Inside Look at Cell Nuclei

Nanotechnology may be in its infancy, but biologists may soon use it to watch the inner workings of a living cell like never before. Scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Lawrence Livermore National Laboratory have developed a way to sneak nano-sized probes inside cell nuclei where they can track life's fundamental processes, such a...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

Nano-sized particles embedded with bright, light-emitting molecules have enabled researchers to visualize a tumor more than one centimeter below the skin surface using only infrared light. A team of chemists, bioengineers and medical researchers based at the University of Pennsylvania and the University of Minnesota has lodged fluorescent materials called porphyrins within the surface of a polyme...

Products containing specific probes for detecting alternative splice forms protected

ExonHit Therapeutics, today announced the grant of a major patent, US # 6,881,571, by the United States Patent and Trademark Office on microarray products allowing the specific detection of mRNAs produced by alternative splicing, covering microarrays optimised for the discovery of alternative RNA splicing events. The patent protects the probe configuration of a unique set of five oligonucleotides...

Duke engineers develop new 3-D cardiac imaging probe

Biomedical engineers at Duke University's Pratt School of Engineering have created a new three-dimensional ultrasound cardiac imaging probe. Inserted inside the esophagus, the probe creates a picture of the whole heart in the time it takes for current ultrasound technology to image a single heart cross section. The new probe has considerable potential not only for evaluating the condition...

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Probe at Biology Products

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. One mL stains 100 minigels. A 500 µL unit size (S-7564) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. 500 µL stains 50 minigels. A 1 mL unit size (S-7568) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO**special packaging* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. A 500 µL unit size (S-7564) and 1mL unit size (S-7568) are available....
Company:Molecular Probes (Invitrogen)

adenosine 5'-O-(3-thiotriphosphate), BODIPY FL conjugated/tagged from Molecular Probes (Invitrogen)

Description:BODIPY FL ATP-Gamma-S binds to ATP-binding proteins. To create this fluorescent nucleotide the BODIPY FL fluorophore was linked through the Gamma-thiol of ATP-Gamma-S. In addition to its potential use for binding studies the BODIPY FL ATP-Gamma-S thioether is an important new substrate for Fhit a member of the histidine triad superfamily of nucleotide-binding proteins....
Company:Molecular Probes (Invitrogen)

SlowFade Antifade Kit from Molecular Probes (Invitrogen)

Description:The active ingredient in Molecular Probes. SlowFadeAntifade Kits is 1,4-diazabicyclo[2.2.2]octane (DABCO), which appears to act as a free radical scavenger that extends useful fluorescence emission. Our original SlowFade formulation (S-2828) was designed to reduce the fading rate of fluorescein to almost zero (Figure 1); it does, however, decrease fluorescein.s fluorescence intensity. Because it...
Company:Molecular Probes (Invitrogen)

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Probe at Biology Technology

New Microarray Labeling Kit for Preparing cDNA Probes

A more reliable and reproducible way to create fluorescently orradioactively labeled cDNA David T. Wong Heidi Davis Darryl Garrison TerryPayette Matt Lundy Kim Kuplent Mary A. Buchanan Joseph A. Sorge Rebecca L. Mullinax Stratagene Phenogenex Nucleic acid micro...

QuantiTect Probe PCR Kit

For quantitative, real-time PCR and two-step RT-PCR using sequence-specific probes Component Included Concentration QuantiTect Probe PCR Master Mix...

RNase Protection Assay (RPA) Using DIG-Labeled RNA Probes

The ribonuclease protection assay (RPA) is a highly sensitiveand specific method for the detection and quantitationof mRNA species. The assay was made possibleby the discovery and characterization of bacteriophageencodedDNA-dependent RNA polymerases (SP6, T7,and T3)....

Detection of mRNAs on Cryosections of the Cardiovascular System Using DIG-Labeled RNA Probes

The following protocol was optimized from a protocolusing 35S-labeled RNA probes [1, 2]. In research studies,it enables detection of the expression of rare mRNAs inthe cardiovascular system (e.g., of the proinflammatorycytokine granulocyte macrophage colony stimulating...

The Flexible matriXarray Chip System: A New Perspective for Probe Optimization in Gene-Expression Profiling

In general, oligonucleotide microarrays are composed ofa two- or three-dimensional solid surface where DNA,used as a capture molecule (probe), is attached in anorderly fashion. Each of the oligonucleotide probes onthe microarray corresponds to a specific target gene,...

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Probe at Biology Dictionary

Single locus probe

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Multi-locus probe

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Probe at Medicine News

New scalpel probes into cancer

A smart scalpel which is able to detect the presence of cancer cells beneath layers skin, blood and muscle have been developed by US researchers. The bottle-top sized microcavity laser developed by the US department of Energy will enable surgeons to operate more accurately on tumours without cutting large amounts of tissue.// This device could detect which cells were cancerou...

The Bio-probe –“ Boon to women ?

With the new device called the Bio probe being developed, screening women for cervical cancer could be made lot easier.” // The Bio-probe has to be inserted into the vagina, and the woman herself can do it. The probe remains inserted for 10 seconds while it measures electrical resistance. It is so small that women would feel more comfortable using the device than with than taking up the...

Research Fraud By Doctor – Probe Demanded

A leading health activist in Kerala has called for a government probe into an Uttar Pradesh-based doctor, in the dock for research fraud by reputed publications, The Lancet and the British Medical Journal. // "The credibility of the medical research community of our country will be questioned unless the Indian Council for Medical Research (ICMR) or a government-appointed body investigate...

Tamiflu Shortage Can Be Better Handled By Combining It With Probenecid

Drug Synergism refers to the enhancement in action or effect of a particular drug than the individual effect of both the drugs combined. The phenomenon could be exploited in the present scenario where the avian bird flu is posing a serious threat across different regions of the globe. // Tamiflu is a prescribed drug for seasonal flu, because it will be a first line of defense if the H...

Three In One Ultrasound Probe For 3-D Imaging Of Heart And Tissue Destruction Developed

Engineers at the Duke University are working on a technology that may someday enable physicians to use high frequency ultrasound waves both to visualize the heart's interior in three dimensions and then selectively destroy heart tissue with heat to correct arrhythmias.// This is the first time a three in one attempt has been made regarding 3-D imaging, ultrasound and therapy. The rese...

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Probe at Medicine Products

Ritleng Probe

Description:Instrument necessary for insertion of Ritleng Bicanaliculus systems and of Self-Threading Monoka systems....
Company:FCI Ophthalmics Inc.

Bodian Lacrimal Pigtail Probe

Description:12 mm diameter pigtail curved probes with eyes 4mm back of blunt ends. Stainless steel. Round knurled handle with polished finish. Overall length: 5.9 inches....
Company:Bausch & Lomb Storz

Storz Pigtail Probe

Description:8 mm diameter curved probes with suture eyes just back of blunt ends. Stainless steel. Round knurled handle with polished finish. Overall length: 5.6 inches....
Company:Bausch & Lomb Storz

Worst Pigtail Probe

Description:9 mm diameter pigtail curved blunt probes. Stainless steel. Round knurled handle with polished finish. Includes pre-cut polyethylene tubes. Overall length: 5.9 inches....
Company:Bausch & Lomb Storz

Beyer Pigtail Probe

Description:16 mm diameter curved probes with suture eyes just back of blunt ends. Stainless steel. Round knurled handle with polished finish. Overall length: 5.7 inches....
Company:Bausch & Lomb Storz

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Probe at Medicine Technology

Neoprobe Phase 2 Lymphoseek Trial Meets Primary Endpoint

DUBLIN, Ohio--(BUSINESS WIRE)--Jun 20, 2007 - Neoprobe Corporation(OTCBB:NEOP), a diversified developer of innovative oncology andcardiovascular surgical and diagnostic products, today announcedpositive preliminary results from a multicenter Phase 2 clinicalstudy of its lead clinical candidate, Lymphoseek(R) (TechnetiumTc99m DTPA-mannosyl-dextran). Lymphoseek is a proprietaryradioactive tar...