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U-M scientists discover identifying markers for primitive blood-forming stem cells

Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood. By reading the bar code, scientists can separate stem cells from their more advanced descen...

Using nature's most primitive anti-viral defense system to find new approaches to cancer research

The humble fruit fly and a grant from the AICR ?the Association for International Cancer Research - are helping a leading scientist in London identify potential targets for drugs that block the spread of cancer. In one of the first studies of its kind, Dr Buzz Baum of the UCL Branch of the global Ludwig Institute for Cancer Research (LICR) is using the tiny fruit fly, Drosophila, as a sim...

Primitive yeast yields secrets of human cholesterol and drug metabolism

By first probing the way primitive yeast make cholesterol, a team of scientists has discovered a long-sought protein whose human counterpart controls cholesterol production and potentially drug metabolism. The collaborative study by investigators at Johns Hopkins University School of Medicine, Vanderbilt University, Indiana University and Eli Lilly Co., was published in the February issue...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

Now, a team of Canadian scientists has identified 1,155 genes und...
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Primitive Yeast Yields Secrets Of Human Cholesterol And Drug Metabolism

By first probing the way primitive yeast make cholesterol, a team of scientists has discovered a long-sought protein whose human// counterpart controls cholesterol production and potentially drug metabolism. The collaborative study by investigators at Johns Hopkins University School of Medicine, Vanderbilt University, Indiana University and Eli Lilly Co., was published in the February...

Genes Associated With Limb Development is More Primitive Than Believed

A new study by a University of Chicago researcher has revealed that fish possessed the genes associated with helping to grow hands and feet (autopods) much before animals with limbs (tetrapods) came onto the scene about 365 million years ago. Lead author of the study in the Nature, Dr Marcus Davis said, the findings overturned a long held, but much debated theory that limb acquisit...
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