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Pretreatment in Medical News

High Pretreatment PSA Velocity Predicts Worse Outcome

The most significant single predictor of aggressive prostate cancer is an elevated rate of increase in prostate specific antigen (PSA) levels, according to a new study. The study found that a pre-treatment rate of PSA increase, called PSA velocity, of more than 2 ng/ml/year was strongly associated...

Genetic testing may be valuable in treating colorectal cancer

...y scientists at Weill Cornell Medical College has determined that so-called pretreatment pharmacogenetic testing is only beneficial if dose-reduced treatment is sho...ll Medical College. "Our study points to significant potential benefits for pretreatment pharmacogenetic testing for metastatic colorectal cancer, but remains to be...

New HIV Study Shows That Large Numbers of Women and People of Color Can Be Successfully Enrolled In U.S. HIV Clinical Studies

... during treatment. Increased AST/ALT monitoring should be considered in patients with underlying chronic hepatitis, cirrhosis, or in patients who have pretreatment elevations of transaminases, especially during the first several months of PREZISTA/r treatment. Evidence of new or worsening liver dysfunction (inclu...

May 14, 2009: Biodesix Announces VeriStrat(R) Data in Head and Neck Cancer to be Presented at ASCO

... this is a targeted pathway. This brings us one step closer to a healthcare model that is highly personalized." About VeriStrat: VeriStrat is a pretreatment serum, proteomic test for patients with advanced NSCLC. The test identifies patients who are likely to have good or poor outcomes after treatment wit...

Biodesix Advances the Field of Personalized Medicine With the Launch of VeriStrat(R)

...oncologists in both key centers of excellence and large community practices throughout the U.S.," said Brunel. About VeriStrat: VeriStrat is a pretreatment serum, proteomic test for patients with advanced NSCLC. The test identifies patients who are likely to have good or poor outcomes after treatment wit...

Transplanted liver cells function in older animals but do not proliferate as much as in younger ones

...organs) was significantly higher in the juvenile rats. The next step, say Dr. Stock and Dr. Christ, is to inject IGF1 in old rats and see if this pretreatment would increase the proliferation levels of hepatocyte cells. ...

MRI and PET/CT improve cervical cancer patient's chances for optimal treatment

... pretreatment MRI and PET/CT for cervical cancer may direct more women to optimal therapy...investigators developed a decision-analytic model to determine the value of pretreatment imaging with MRI and/or PET/CT in patients with FIGO Stage IB cervical canc...

Electroacupuncture protects acetylsalicylic acid-induced acute gastritis in rats

...s compared to the NSAID-induced ulceration group. The inducible expression of COX-1 in the early phase and COX-2 in the late phase suggests that EA pretreatment might up-regulate the mucosal defense mechanism. The total NO concentration in the EA group was significantly increased with respect to that of the NS...

PREZISTA(R) Now Available for Pediatric Patients Six Years of Age and Older as part of HIV Combination Therapy

... during treatment. Increased AST/ALT monitoring should be considered in patients with underlying chronic hepatitis, cirrhosis, or in patients who have pretreatment elevations of transaminases, especially during the first several months of PREZISTA/r treatment. Evidence of new or worsening liver dysfunction (inclu...

Schering-Plough Announces FDA Approval of PEGINTRON(TM) and REBETOL(R) Combination Therapy for Treating Pediatric Hepatitis C

...erapy (excluding those with HCV genotype 2 or 3) should be discontinued from therapy at week 12 if their HCV RNA dropped less than 2 log10 compared to pretreatment or at 24 weeks if they have detectable HCV RNA at treatment week 24. During the course of therapy lasting up to 48 weeks in patients 3 to 17...
Pretreatment in Medical Technology

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

...tment period. Patients were on average 65 years old (54-84) and had an average lumbar spine BMD T-score of -2.93. All patients underwent four weeks of pretreatment with standard regional supplementation requirements for osteoporosis of not less than 400 IU per day of Vitamin D and not less than 500 mg per day of ...

NeurogesX Announces Preliminary Results of FDA-Requested Qutenza(TM) Study

...tients with postherpetic neuralgia (PHN) following pretreatment with an FDA-approved topical anesthetic. As part o...imilar tolerability to the topical agent used as a pretreatment in the clinical development program. The NDA for Q...te Qutenza patch application following a 60-minute pretreatment with an FDA-approved topical anesthetic (2.5% lido...

Ironwood and Forest Present Additional Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation

... 600 ug linaclotide or placebo administered orally once daily to adults meeting modified Rome II criteria for IBS-C. Participants underwent a two-week pretreatment (baseline) period before undergoing the 12-week treatment period, followed by a two-week post-treatment period. Daily assessments of bowel habits and ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

...m creatinine in duplicate before initiating therapy to establish a reliable pretreatment baseline, due to variations in measurements. Monitor serum creatinine month...de by 10 mg/kg if rise in serum creatinine to > 33% above average of the pretreatment measurements is seen at 2 consecutive visits, and cannot be attributed to o...

CureDM's Diabetes Therapy Achieves Major Development Milestone

...w insulin-producing cells through islet neogenesis can potentially reverse both type 1 and type 2 diabetes. Patients with type 1 diabetes will require pretreatment with an immune tolerance agent to protect new islets formed by HIP. CureDM, Inc., located at the Lankenau Institute for Medical Research on the Lanken...

NPS Reports Successful GATTEX(TM) Extension Study

...ion in PN after a total of 52 weeks of therapy. -- Patients treated with low-dose GATTEX demonstrated a mean 51% reduction in PN volume from pretreatment baseline to the end of 52 weeks of therapy (p a mean 24% reduction (p< 0.001). -- Six out of six (100%) patients who had previously received...

New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ

...ed by the results which showed that following 6 month treatment with Nasacort AQ, the stature-for-age distribution did not appear to shift compared to pretreatment in children aged 2-5 years who suffer from year-round allergies." This is one of the first controlled studies in the U.S. designed to investigate bo...

US Oncology Research Network Presents Clinical Studies at San Antonio Breast Cancer Symposium

...yclophosphamide followed by docetaxel-capecitabine for stage 2, 3 breast cancer," was conducted among women with stage 2-3 breast cancer who underwent pretreatment fine needle aspiration (FNA) preserved in RNAlater(R) and shipped to Lajos Pusztai, M.D., Associate Professor at M.D. Anderson Cancer Center. Tissue...

PNH Patients With Lower Levels of Hemolysis, Mild Anemia and Minimal Transfusion Support Have Significant Disease Burden; Soliris(R) Therapy Provided Clinical Improvements in PNH Patients Regardless of Disease Severity

...ated with significant improvements in fatigue (as measured by the FACIT-Fatigue instrument), regardless of the baseline level of hemolysis, anemia, or pretreatment transfusion requirements. At baseline, patients who had the lowest levels of hemolysis, mild anemia, or minimal transfusion requirements reported fati...

Studies Suggest Key Correlation Between Lung Cancer Subtype and Treatment Outcomes

... and the platelet count is greater than or equal to 100,000 cells per millimeter cubed and creatinine clearance is greater than or equal to 45mL/min. pretreatment with dexamethasone or its equivalent has been reported to reduce the incidence and severity of skin rash. The effect of third space fluid, such as pl...
Pretreatment in Medical Products

Epstein-Barr Virus (EBV) VCA IgM Recombinant IFA (RIFA)

Description:...CA). Each kit contains ten 12-well slides prepared with recombinant EBV VCA antigen, FITC IgM RIFA: conjugate, positive and negative controls, and IgM pretreatment Diluent....
Company:Focus Diagnostics

Estrone Sulfate EIA

Description:... Direct assays, no sample extraction, hydrolysis or other pretreatment required. Highly specific antiserum, minimal cross-reactivity with estrone, estradiol and other estrogen metabolites....
Company:Diagnostic Systems Laboratories, Inc.

Testosterone Enzyme Immunoassay Test Kit

Description:... The Testosterone Enzyme Immunoassay is intended for the quantitative determination of Testosterone concentration in human serum. No special pretreatment of the sample is necessary. For in vitro Diagnostic use only....
Company:BioCheck, Inc.

Testosterone ELISA

Description:... The Testosterone ELISA is intended for the quantitative determination of testosterone concentration in human serum. No special pretreatment of the sample is necessary....
Company:Calbiotech, Inc.

Direct-Q Water Purification System (with pump)

Description:...s when routine maintenance should be performed. Applications Culture Media Buffers Blanks or Standard Solutions Features Progard plug-in pretreatment pack Constant water flow-rate Automatic refilling of the 10 L reservoir Quiet operation ...
Company:Millipore

Direct-Q Water Purification System (w/o pump)

Description:...s when routine maintenance should be performed. Applications Culture Media Buffers Blanks or Standard Solutions Features Progard plug-in pretreatment pack Constant water flow-rate Automatic refilling of the 10 L reservoir Quiet operation ...
Company:Millipore

RiOs 200 Water System

Description:...very Constant product flow rate independent of temperature from 7 - 30 C Built-in UV lamp for bacteria-sensitive applications Easy-to-replace pretreatment packs, tailored to the feedwater source Built-in resistivity monitoring to ensure water quality ...
Company:Millipore

RiOs 150 Water System

Description:...very Constant product flow rate independent of temperature from 7 - 30 C Built-in UV lamp for bacteria-sensitive applications Easy-to-replace pretreatment packs, tailored to the feedwater source Built-in resistivity monitoring to ensure water quality ...
Company:Millipore

RiOs 100 Water System

Description:...very Constant product flow rate independent of temperature from 7 - 30 C Built-in UV lamp for bacteria-sensitive applications Easy-to-replace pretreatment packs, tailored to the feedwater source Built-in resistivity monitoring to ensure water quality ...
Company:Millipore

RiOs 50 Water System

Description:...very Constant product flow rate independent of temperature from 7 - 30 C Built-in UV lamp for bacteria-sensitive applications Easy-to-replace pretreatment packs, tailored to the feedwater source Built-in resistivity monitoring to ensure water quality ...
Company:Millipore
Pretreatment in Medical Dictionary

Bronchospasm

...asm - a spasm of the bronchi that makes exhalation difficult and noisy; ... Discussion: Which of these two medications is more effective? ... pretreatment with Albuterol vs Montelukast: Exercise-Induced Bronchospasm : Discussion ... What is exercise-induced bronchospasm ? ... There are reports of a...

Anaerobic

...n anaerobic training at Smarter. Shop online, compare products, and save. Anaerobic treatment is a biological process ideally suited for the pretreatment ... The anaerobic process utilizes naturally-occurring bacteria to break down ... Information about anaerobic in the free online English dic...
Pretreatment in Biological News

Fuel from fiber -- Pretreatment can put corn stalks, trees in your car's tank

"Put a tree in your tank." Fuel companies aren't touting that slogan. At least not yet. But thanks to research done in part by Bruce Dale, Michigan State University professor of chemical engineering and materials science, making fuels from poplar trees and corn stalks is becoming more efficient a...

New technique can fast-track better ionic liquids for biomass pre-treatments

...r the first time to dynamically track solubilization during an ionic liquid pretreatment of a biomass sample, and to accurately and quickly assess the liquid's perf...on of Biomass Solubilization and Cellulose Regeneration During Ionic Liquid pretreatment of Switchgrass" Co-authoring the paper with Simmons were his JBEI colleague...

Tips from the journals of the American Society for Microbiology

...to death than wild-type mice. Both the HK/483 and H/K 486 virus caused a similar systemic infection in INF-a/β receptor-deficient mice, however, pretreatment with IFN-a/β significantly reduced replication of both viruses. "These results suggest a role for the IFN-a/β response in the control of ...

Gutsy germs succumb to baby broccoli

...lori shed into the stool of infected people. There was no HpSA level change in control subjects who ate alfalfa sprouts. The HpSA levels returned to pretreatment levels eight weeks after people stopped eating the broccoli sprouts, suggesting that although they reduce H. pylori colonization, they do not eradic...

Team identifies a molecular switch linking infectious disease and depression

...ain. Just as before, the mice exposed to BCG exhibited typical sickness behavior (low appetite, reduced activity), from which they soon recovered. But pretreatment with the IDO inhibitor eliminated the subsequent development of depressive-like behavior. Mice that had the IDO gene deleted were also completely resi...

HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection

...hymoquinone shares a structural homology with ubiquinone (mitochondrial component) it is likely that it may act as a mitochondrial antioxidant. Indeed pretreatment of pancreatic beta-cells with thymoquinone caused a reversal of nelfinavir induced deleterious effects. Thymoquinone decreased the production of reac...

Process can cut the cost of making cellulosic biofuels

...st of making biofuels from cellulose. The AFEX (ammonia fiber expansion) pretreatment process, developed by Bruce Dale, University Distinguished Professor of che...been a major issue slowing cellulosic ethanol production. Using AFEX as the pretreatment process can dramatically reduce the cost of making biofuels from cellulose....

New UGA biomass technology dramatically increases ethanol yield from grasses and yard waste

...he new technology features a fast, mild, acid-free pretreatment process that increases by at least 10 times the am...that digest it, producing simple sugars. The harsh pretreatment solutions subsequently must be removed and dispose...dly UGA technology eliminates the expense of harsh pretreatment chemicals and their disposal, and the formation of...

A search for protection against chemotherapy cardiotoxicity

...prevents acute cardiotoxic effects induced by doxorubicin and trastuzumab exposures. The research article describing this work entitled Erythropoietin pretreatment protects against acute chemotherapy toxicity in isolated rat hearts will be featured in the January 2008 issue of Experimental Biology and Medicine. A...

High-dose anticlotting drug cuts heart attack, death risk in half

... pretreatment with double-dose anticlotting medication just before percutaneous coronary ...0 mg. A few received either 450 mg or 900 mg of clopidogrel. Overall, pretreatment with high-dose clopidogrel (600 mg or more) was associated with a 50 percen...
Pretreatment in Biological Technology

NeurogesX Reports Second Quarter 2009 Results

...rom FDA-requested Qutenza study (Study C123) in patients with PHN following pretreatment with FDA-approved topical anesthetic Announced FDA orphan drug desig...nesthetic would provide similar tolerability to the topical agent used as a pretreatment in the clinical development program. The study, conducted in patients with ...

NeurogesX Provides U.S. Regulatory Update for Qutenza(TM)

... Study to Evaluate FDA-Approved Topical Anesthetic pretreatment SAN MATEO, Calif., June 10 /PRNewswire-First...ients with post-herpetic neuralgia (PHN) following pretreatment with an FDA-approved topical anesthetic. As part o...n (NDA) review, the FDA wants to determine whether pretreatment with an FDA-approved topical anesthetic would prov...

Abbott & BioGenex Extend the Technology Co-development and Distribution Agreement for Marketing the Xmatrx(R) Advanced Staining Platform for the Automation of FISH, IHC and ISH Molecular Diagnostic Assays

...covery through clinical diagnostics." The Xmatrx(R) platform allows for the walk-away automation of the entire FISH assay workflow, from specimen pretreatment to final cover-slipping and is designed for optimal results with Abbott Molecular AutoFISH(TM) reagents and FISH technology. The Xmatrx will be c...

Gold-palladium nanoparticles achieve greener, smarter production of hydrogen peroxide

...n be greatly reduced by depositing gold-palladium nanoparticles on a high-surface-area carbon support that has first been washed with nitric acid. The pretreatment decreases the average size of the particles from a range of 2 to 70 nanometers (1 nm equals one-billionth of a meter) to a range of 2 to 25 nm. The wa...

Katrina Proven Certified Organic Toxic Mold Remedy Now Available for Mold Remediation Professionals and Homeowners

...ur initial assessment under the conditions on this project is that it works great. Our site superintendent prefers it over some of the anti-microbial pretreatment products we have been using for years. I'm sure we'll be ordering more. However, don't run around thinking anyone can apply this stuff to remedy a m...

DOE JGI Director Eddy Rubin highlights the genomics of plant-based biofuels in the journal Nature

...rtation needs." In the Nature Review, Rubin describes the processes entailed in biofuel production from lignocellulose: the harvesting of biomass, pretreatment and saccharification, which results in the deconstruction of cell wall polymers into component sugars, and then the conversion of those sugars into bi...

Radiesse(R) Dermal Filler Featured Prominently in Journal of Dermatologic Surgery Special Issue on Fillers

...ne if the addition of anesthetic agents to prefilled Radiesse syringes could provide sufficient anesthetic effect to warrant reduction of conventional pretreatment anesthetic procedures. Through a multitude of laboratory tests the authors determined that the addition of lidocaine to Radiesse filler can be accom...

Quest PharmaTech Announces Interim Results from Phase I/II Clinical Trial for Photodynamic Treatment for Hair Removal

...udy will be used to guide the design of future clinical development. Skin pretreatment and Follicular Uptake Thirty healthy subjects were enrolled to evaluate t...f Intense Pulse Light (IPL) ranging from 4.5J/cm(2) to 20.0J/cm(2). No skin pretreatment technique was used. No unexpected side effects were observed at any of the ...

DuPont and Genencor Create World-Leading Cellulosic Ethanol Company

...ners' individual technology platforms will combine: -- A differentiated pretreatment process developed by DuPont through its collaboration with the U.S. Dep...rough multiple grants totaling more than $60 million for the development of pretreatment processes, advanced ethanol conversion organisms and improved enzymes. Du...

Oncolytics Biotech Inc. Starts Patient Enrolment in U.K. Combination REOLYSIN(R)/Cyclophosphamide Trial

...e more information on how we might improve the effectiveness of this promising new approach to treating cancer," said Dr. Spicer. "In animal models, pretreatment with low-dose immune modulators has been shown to significantly enhance the antitumour activity of REOLYSIN(R)(ref.)," added Dr. Brad Thompson, Presid...
Pretreatment in Biological Products

PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (10X) from Lab Vision

Description:... formal-fixed tissues. The product is designed to be used in the Lab Vision pretreatment Module TM . Determination of use conditions in any other insrument is the responsibility of the user. The Lab Vision pretreatment Module TM is designed to be used with slide racks used in the Lab vision 3...
Company:Lab Vision

PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (100X) from Lab Vision

Description:... formal-fixed tissues. The product is designed to be used in the Lab Vision pretreatment Module TM . Determination of use conditions in any other insrument is the responsibility of the user. The Lab Vision pretreatment Module TM is designed to be used with slide racks used in the Lab vision 3...
Company:Lab Vision
Pretreatment in Biological Dictionary

Thylakoids

...IM in thylakoids from C. reinhardtii and C. sorokini ... ... experimental system composed of thylakoids isolated from senescing leaves ... acid pretreatment of the thylakoids and it is inferred that the protease ... ... peripheral proteins in the thylakoids of pea were systematically ... Thylak...

Nick translation

... and dTTP solutions (200 ... The Nick Translation Kit is desigined for fluorescence labelling ... Nick Translation Kit. Microscope Filters. pretreatment Kits. UroVysion® Proficiency Panel ... ideally the length of the DNA should be 500-900 bp after nick translation . ... 9. Stop the nick trans...
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