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Prednisone in Medical News

Modified-Release Prednisone May Ease Rheumatoid Arthritis

Pill timed to body's rhythms, helps with morning joint stiffness, researchers say THURSDAY, Jan. 17 (HealthDay News) A modified-release form of the steroid prednisone is better than the standard, immediate-release version at reducing morning joint stiffness in people with rheumatoid arthritis, ...

Flu Shot May Be Less Effective in Those With Lupus

...his dip in cell-mediated responses was linked to the use of the medications prednisone and/or azathioprine, the researchers added. Flu vaccination did not impa...ality due to influenza virus infection, in particular in patients receiving prednisone and/or azathioprine," the researchers advised. They also called for more in...

Immune responses to flu vaccine are diminished in lupus patients

...d responsiveness of T cells in general. However, the use of the medications prednisone and/or azathioprine was associated with lower cell-mediated responses follo...ality due to influenza virus infection, in particular in patients receiving prednisone and/or azathioprine," they state, adding that evaluating clinical protectio...

63 percent of RA patients suffer psychiatric disorders, with depressive spectrum conditions most likely

...(p=0.02) in patients older than 50 years (39% vs. 9%) The age of the first prednisone intake was significantly higher (p Dr Tatiana Lisitsyna from the State I... was assessed using DAS28* with a median score of 4.98 (3.71 - 6.4). Median prednisone intake duration was 34 months (3-72) and 80% of patients were taking DMARDs...

Exercise improves functional and psycological ability and reduces steroid need in rheumatoid arthritis

...ment in the walk time test (p=0.063) 62% of patients reported a reduced need for daily corticosteroid intake, from a mean dosage of 5.3mg/day of prednisone to 3.1mg/day (p=0.038) 32% of patients reported stopping concurrent NSAID (non-steroidal anti-inflammatory drug) treatment altogether following the ...

Poniard Pharmaceuticals Announces Positive Efficacy and Safety Data From Phase 2 Clinical Trial of Picoplatin in Men With Metastatic Prostate Cancer

... that picoplatin in combination with docetaxel and prednisone is active as first-line therapy for metastatic CRP... that picoplatin in combination with docetaxel and prednisone is active as first-line therapy for CPRC," said Wi...nt of picoplatin in combination with docetaxel and prednisone as a first-line chemotherapy regimen for metastati...

Study shows that maintenance rituximab is useful for advanced indolent lymphoma

... novel antibody, rituximab (MR) following cyclophosphamide, vincristine and prednisone (CVP) therapy improves progression-free survival in patients with stage III...OG) titled, "Maintenance Rituximab After Cyclophosphamide, Vincristine, and prednisone Prolongs Progression-Free Survival in Advanced Indolent Lymphoma: Results o...

Experimental Drug May Dampen Severe Asthma

... month. Everyone in this study had severe, prednisone-dependent asthma. prednisone is an oral steroid that is generally quite effective in treating asthma but...t. Additionally, those taking the drug were able to reduce their dosage of prednisone more than people on placebo could. Mepolizumab was not associated with a...

Varicella zoster infection causes severe autoimmune hepatitis

...refused a liver biopsy, therefore, they started him on a tapering course of prednisone for presumed AIH, at a starting dose of 60 mg. He responded to that dramati...n tapering his steroids below 10 mg, his liver enzymes increased again. His prednisone dose was increased to 30 mg and 50 mg azathioprine was added, however, beca...

Poniard Pharmaceuticals Provides 2009 Clinical Data Goals for Picoplatin

...is evaluating the efficacy and safety of picoplatin administered every three weeks in combination with full-dose docetaxel and daily prednisone as a first- line treatment in patients with metastatic HRPC or CRPC who have not received prior chemotherapy. PSA response (defined ...
Prednisone in Medical Technology

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

...ved within 4-8 weeks. -- A higher percentage of patients in both belimumab treatment groups, versus placebo, had their average prednisone dose reduced by at least 25% from baseline to 7.5 mg per day or less during the last 12 weeks of study (p=0.053 for 10 mg/...

Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting

...lticenter, phase I/II study of AT-101 in combination with docetaxel (D) and prednisone (P) in men with castrate resistant prostate cancer (CRPC). Abstract #5062;...lticenter, phase I/II study of AT-101 in combination with docetaxel (D) and prednisone (P) in men with docetaxel refractory prostate cancer. Abstract #5145; Post...

Poniard Pharmaceuticals to Present New Data from Phase 2 Clinical Trials of Picoplatin in Multiple Tumor Types at the 45th Annual Meeting of the American Society of Clinical Oncology

... poster discussion. Poster presentation details are as follows: -- Results of a Phase II study of picoplatin with docetaxel and prednisone in first-line treatment of castration-resistant prostate cancer Abstract #5140 R. De Jager, L. Roman, N. Lopatkin, P. Karlov, ...

Poniard Pharmaceuticals Reports Fourth Quarter and Year End 2008 Financial Results and Provides a Corporate Update

...ruary 2009, Poniard presented updated efficacy and safety data from its ongoing Phase 2 clinical trial of picoplatin in combination with docetaxel and prednisone in patients with metastatic castration-resistant (hormone-refractory) prostate cancer (CRPC) during the American Society of Clinical Oncology (ASCO) 2...

Ascenta Therapeutics Announces Positive Preliminary Results with AT-101 in Docetaxel Refractory Prostate Cancer

... /PRNewswire/ -- Ascenta Therapeutics announced today positive preliminary results from its Phase II study of AT-101 in combination with docetaxel and prednisone (D/P) in men with docetaxel refractory, castrate resistant prostate cancer (CRPC) at the American Society of Clinical Oncology (ASCO) Genitourinary Ca...

Continued Overall Survival Advantage Reported From Pivotal Trial of VELCADE(R) (Bortezomib) for Injection Based Therapy in Patients With Previously Untreated Multiple Myeloma

...ated multiple myeloma given VELCADE, melphalan and prednisone (VcMP). The VELCADE combination demonstrated consi...owed that the addition of VELCADE to melphalan and prednisone continued to demonstrate a long-term survival adva...n cycles 5 through 9) with melphalan 9 mg/m(2) and prednisone 60 mg/m(2) (days 1 through 4 in cycles 1 through 9...

Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients

... (6%), diarrhea (5%), vomiting (4%), and nausea, dehydration, dyspnea and thrombocytopenia (each 3%). In the Phase III VELCADE + melphalan and prednisone study, the safety profile of VELCADE in combination with melphalan/prednisone is consistent with the known safety profiles of both VELCADE and melphal...

Novel VELCADE(R) (Bortezomib) for Injection Based Four-Drug Combination Was Well Tolerated In Previously Untreated Multiple Myeloma Patients

...ia (6%), diarrhea (5%), vomiting (4%), and nausea, dehydration, dyspnea and thrombocytopenia (each 3%). In the Phase 3 VELCADE + melphalan and prednisone study, the safety profile of VELCADE in combination with melphalan/prednisone is consistent with the known safety profiles of both VELCADE and melphal...

Isis Announces That OGX-011 Has Shown Overall Survival Advantage in Prostate Cancer Compared to Standard Therapy in a Randomized Phase 2 Study

...domized Phase 2 clinical trial of OGX-011 in combination with docetaxel and prednisone ("the OGX-011 arm") compared to docetaxel and prednisone alone ("the control arm") for first-line treatment of metastatic castrate r...

September 2008 Mayo Clinic Health Letter Highlights Cataract Removal, Severe Headache and Dual Energy X-Ray Imaging

...pends on the type of vasculitis, its severity and the patient's overall health. The anti-inflammatory properties of corticosteroid medications such as prednisone and methylprednisolone often improve symptoms within days. Immune-suppressing and cytotoxic drugs are used when vasculitis is severe and does not resp...
Prednisone in Medical Dictionary

Hypercalcemia

...mia Definition Hypercalcemia is an When it comes to hypercalcemia , prednisone enables the kidney to dump extra ... Lymphoma remains the most common cau... disorder commonly encountered by ... When it comes to hypercalcemia , prednisone enables the kidney to dump extra ... Lymphoma remains the most common cau...

Eczema

... Atopic eczema consists of chronic inflammation; it often occurs in people with a ... If the eczema is especially severe, a doctor may prescribe prednisone or ... ...
Prednisone in Biological News

Prednisone tablets less variable than marketed drugs

...study comparing the dissolution variability of USP prednisone Lot P Reference Standard tablets to two marketed d...Study results clearly show less variability in USP prednisone Lot P tablets than in the marketed tablets. Dissol...ng, the performance verification test involves USP prednisone Reference Standard tablets. The current study expl...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...y identified a drug that can overcome therapy-resistant cases of acute lymphoblastic leukemia (ALL) in children. So-called "glucocorticoid" drugs like prednisone are very effective in many cases of ALL, but in some patients the cancer cells are resistant to the drugs, which often can lead to fatal results. ...

Combination therapy improves AIDS-related lymphoma outcome

...s white blood cells. They are treated with chemotherapy, often consisting of a multi-drug regimen using cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP). People with HIV, a virus that depletes integral, specialized white cells called CD-4 cells, are at increased risk of developing lymphomas, par...

New type of rejection blocker protects kidneys after transplant

...tion compared to one-third of patients in the two belatacept groups. Over the past 20 years, drugs like cyclosporine (a calcineurin inhibitor) and prednisone (a corticosteroid) have been highly successful in overcoming organ rejection. However, Vincenti said, advances have only been modest in terms of keepi...
Prednisone in Biological Technology

Automated Dissolution of Prednisone with the MultiDose G3

Jayne M. Brown, Lynn Jordan, Dale Von Behren Caliper Life Sciences Corporation, Applications Laboratory, Hopkinton, Massachusetts, USA Introduction Prednisone is commonly used in laboratories as a dissolution bath calibrator. Manual dissolution is a very ...

Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update

...h metastatic CRPC at the 2009 ASCO Annual Meeting. The updated efficacy and safety data demonstrated that picoplatin in combination with docetaxel and prednisone is active as first-line therapy for metastatic CRPC as demonstrated by several endpoints, including reductions in prostate specific antigen (PSA) leve...

Ascenta Therapeutics Announces Presentation of Promising Results From Clinical Trials of AT-101 in Prostate, Brain, and Lung Cancers at 2009 ASCO Annual Meeting

... study of AT-101 in combination with docetaxel and prednisone in men with castrate-resistant prostate cancer (CR...dy of AT-101 in combination with docetaxel (D) and prednisone (P) in men with castrate resistant prostate cancer...dy of AT-101 in combination with docetaxel (D) and prednisone (P) in men with docetaxel refractory prostate canc...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

...r week of OGX-011 by intravenous infusion in combination with docetaxel and prednisone or docetaxel and prednisone alone. Patients in both treatment arms receive therapy until disease progre...

OncoGenex Reports First Quarter Financial Results

...e 2 clinical trial which compared OGX-011 in combination with docetaxel and prednisone to docetaxel and prednisone alone for first-line treatment of metastatic castrate resistant prostate ca...

OncoGenex Receives Confirmation from FDA on the Design of a Second Phase 3 Trial Evaluating OGX-011 for the Treatment of Advanced Prostate Cancer

...n survival for patients receiving OGX-011 in combination with docetaxel and prednisone was 27.5 months, compared to 16.9 months in patients receiving docetaxel and prednisone alone. Updated survival results will be presented at the 2009 Annual Meetin...

OncoGenex Reports Financial Results for Fourth Quarter and Fiscal Year 2008 and Provides Outlook for 2009

... survival duration, estimated at 10.6 months, in a randomized Phase 2 clinical trial of OGX-011 in combination with docetaxel and prednisone ("the OGX-011 arm") when compared to docetaxel alone ("the control arm") for first-line treatment of metastatic CRPC. The median survi...

Poniard Pharmaceuticals Announces New Efficacy and Safety Data from a Phase 2 Picoplatin Trial in Patients with Prostate Cancer

...al of picoplatin in combination with docetaxel and prednisone as first-line therapy for metastatic castration-re...fit when picoplatin is combined with docetaxel and prednisone as a first-line therapy for patients with CRPC," s...cal trial to compare picoplatin with docetaxel and prednisone to docetaxel and...

OncoGenex Provides Update on Two-Year Survival Data from Ongoing Phase 1/2 Clinical Trial of OGX-011 in Non-Small Cell Lung Cancer

...n survival for patients receiving OGX-011 in combination with docetaxel and prednisone was 27.5 months, compared to 16.9 months in patients receiving docetaxel and prednisone alone. At the 2008 Annual Meeting of the American Society of Clinical Oncol...

Poniard Pharmaceuticals to Present Data from Phase 2 Clinical Trials of Picoplatin in Colorectal and Prostate Cancers

...30-1:30 -- The ASCO 2009 GU Cancers Symposium, Orlando, Fla. -- Results of a Phase 2 study of picoplatin with docetaxel and prednisone in first-line treatment of metastatic hormone refractory prostate cancer (HRPC) -- R. Earhart, L. Roman, N. Lopatkin, P. Karlov, ...
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