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Prednisolone in Medical News

Once-a-Year Drug Helps Counter Steroid-Linked Bone Loss

... Specifically, Reclast (zoledronic acid) was found to hold off and/or reverse bone loss among patients taking a glucocorticoid medication (including prednisolone or prednisone) for one of several inflammatory and immune-related diseases, including asthma, lupus and rheumatoid arthritis. And it did so more effe...

Common Asthma Treatments Don't Work for Virus-Induced Wheeze

...rom British researchers, looked at the use of oral prednisolone and found no significant differences between the t...in toddlers and preschoolers. The study of oral prednisolone included 700 children between the ages of 10 month... course of between 10 milligrams and 20 milligrams prednisolone depending on their age or a placebo for five days....

50 percent of recent onset RA patients become free of signs and symptoms within 36 weeks

...exate Every 3 months thereafter, therapy could be adjusted based on DAS28, also using other TNF-blockers. Patients were allowed to take NSAIDs, and prednisolone ≤10mg/day and intra-articular corticosteroid injections could be administered Dr. H. Kuper and Prof M. van de Laar of Medisch Spectrum Twent...

Sirion Therapeutics Receives NDA Acceptance and Priority Review From the FDA for Durezol(TM) in the Treatment of Postoperative Ocular Inflammation

...ial to treat patients suffering from ocular inflammatory diseases, including post-operative inflammation. Durezol(TM) is a difluorinated derivative of prednisolone and has potent anti- inflammatory activity. The efficacy and safety of Durezol(TM) in ocular inflammatory diseases has been demonstrated in an extensi...

KV Pharmaceutical Company Completes Unaudited Fiscal 2007 Results; Receives Trading Extension From NYSE

...orporation received three approvals from the FDA, including: Diltiazem HCL extended release capsules, Nystatin Topical Powder and a new formulation of prednisolone Sodium Phosphate. The Company remains optimistic about the potential FDA approvals of important new Abbreviated New Drug Applications (ANDA's) from it...

FLAVORx Teams up with Wedgewood Pharmacy to Make it Even Easier to Make Pet Medications Taste Good

...bed for treatment of seizures in dogs; -- Clindamycin 25MG/ML, an antibiotic; -- Metronidazole Benzoate 50MG/ML and 100MG/ML, an antifungal; -- prednisolone 5MG/ML, a glucocorticoid; -- Methimazole 5MG/ML: commonly prescribed for hyperthyroidism; -- Cisapride 5 and 10MG/ML, a gastrointestinal prokinetic,...

Antiviral Won't Improve Bell's Palsy Outcome

...oid related to the more commonly known prednisone. prednisolone stops the immune system from creating so much infl...t genital herpes. According to Gilden, a course of prednisolone costs about $10, compared to $200 for the antivira... After nine months, 94 percent of those who took prednisolone had recovered, compared to 85 percent of those who...

Prostate cancer drug not found cost-effective

... Scottish Medicines Consortium said, "The SMC advises NHS boards and area drug and therapeutic committees (ADTCs) that docetaxel in combination with prednisolone is not recommended for use within NHS Scotland for the treatment of patients with metastatic hormone refractory prostate cancer (MHRPC)”. Source: ...

Hope for Patients With HIV

...trial. Only 5 percent of patients who did not take prednisolone had this positive outcome. After five years, more than 10 percent of the patients taking prednisolone had higher T-cell counts than they did at the star...dy. Despite suppressing patients’ immune response, prednisolone did not cause the HIV virus to replicate more vigo...

Steroid Treatment for Wheezing Questioned

...a placebo. More than 200 children with a history of wheezing were part of the study. The children were randomly assigned to a five-day course of oral prednisolone or placebo to be given at the start of a wheeze attack. Parents then recorded their children's respiratory symptoms and noted if their child was taken...
Prednisolone in Medical Technology

CombinatoRx Provides Topline Results from Phase 2 RA Study with CRx-139 and Very Low Dose Prednisolone

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Mar 26, 2007 - CombinatoRx, Incorporated (NASDAQ: CRXX) today announced preliminary results of a phase 2 clinical trial studying CRx-139 (a synergistic combination of 3mg prednisolone and the antidepressant paroxetine) and 3mg prednisolone alone, in patients with ...

Fovea Reports Positive Results with Prednisporin(TM) in Persistent Allergic Conjunctivitis

... a prescription drug with a 10 fold higher dose of prednisolone acetate, in patients treated for the signs and sym...ombination therapy of low doses cyclosporine A and prednisolone acetate was compared to PredForte(TM) alone or veh...mulation of lower than the usual therapeutic doses prednisolone acetate and cyclosporine A, to retain the efficacy...

Sirion Therapeutics Announces Clinical Data Presentations at the 2009 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting

...ata obtained from the interim analysis. Identified below are the presentations scheduled for the upcoming ARVO meeting. Dose Uniformity of prednisolone Acetate Ophthalmic Suspensions Compared to Durezol (difluprednate ophthalmic emulsion) 0.05% Session Date/Start Time: Monday May 4, 8:30-10:15 ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

...pproved for the treatment of inflammation and pain associated with ocular surgery. Difluprednate, the active ingredient in Durezol, is a difluorinated prednisolone derivative that has potent anti-inflammatory activity. Durezol is not approved for the treatment of uveitis. Important Safety Information Like oth...

Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)

...pproved for the treatment of inflammation and pain associated with ocular surgery. Difluprednate, the active ingredient in Durezol, is a difluorinated prednisolone derivative that has potent anti-inflammatory activity. Prior to US approval, the efficacy and safety of difluprednate dosed four times a day in ocular...

Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain

...e treatment of inflammation and pain associated with ocular surgery. Difluprednate, the active ingredient in Durezol, is a difluorinated derivative of prednisolone and has potent anti-inflammatory activity. Prior to U.S. approval, the efficacy and safety of difluprednate in ocular inflammatory diseases had been d...

Innovative Cancer Drug MabThera Again Shown To Improve Survival Rates In Patients With Lymphoma

...n incidence by 80% since the early 1970s. *mitoxantrone, chlorambucil and prednisolone About the study The open-label, randomised study was conducted in 34 ce...Malignancies _ Rituximab Added to First-Line Mitoxantrone, Chlorambucil and prednisolone Chemotherapy Followed by Interferon Maintenance Prolongs Survival in Patien...

Additional Data on CombinatoRx Drug Candidates CRx-102 and CRx-139 Presented at EULAR

...-139. Dr. Emery showed that subjects treated with high dose CRx-139 (3mg of prednisolone and 20mg of paroxetine) showed a benefit in ACR 50 response compared to low dose CRx-139 (3mg of prednisolone and 10mg of paroxetine) or 3mg of prednisolone alone. -- ACR 50 at day 42...
Prednisolone in Biological Technology

Sirion Therapeutics Supplemental New Drug Application for Durezol(TM) to Treat Uveitis is Accepted for Review by the FDA

...pproved for the treatment of inflammation and pain associated with ocular surgery. Difluprednate, the active ingredient in Durezol, is a difluorinated prednisolone derivative that has potent anti-inflammatory activity. Durezol does not contain benzalkonium chloride (BAK), an ocular preservative known to cause co...

ETHEX Corporation Issues Nationwide Voluntary Recall of Products

...8177-202-04, 202-08, 202-09 & 202-11) prednisolone Sodium Oral Solution (58177-932-05) prednisolone Syrup 15mg/5mL (58177-910-05 & 910-07) prednisolone Syrup 5mg/5mL (58177-912-03) Propafenone HCl T...

ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results

.... In addition, we are working towards completing the additional T- Pred work required by the FDA for the testing of tobramycin and the pK study on the prednisolone component of the formulation. We expect to complete these additional T-Pred studies late this year or early 2009. Finally, we expect to announce in th...

Sirion Therapeutics Announces FDA Approval of Durezol(TM) for Treatment of Postoperative Ocular Inflammation and Pain

...ophthalmic corticosteroid for the treatment of postoperative inflammation and pain associated ocular surgery. Durezol is a difluorinated derivative of prednisolone and has potent anti-inflammatory activity. Prior to U.S. approval, the efficacy and safety of Durezol in ocular inflammatory diseases had been demonst...

Sirion Therapeutics Highlights Pivotal Trial Results of Durezol(TM) at the American Society of Cataract and Refractive Surgery Annual Symposium

...ial to treat patients suffering from ocular inflammatory diseases, including post-operative inflammation. Durezol(TM) is a difluorinated derivative of prednisolone and has potent anti-inflammatory activity. The efficacy and safety of Durezol(TM) in ocular inflammatory diseases has been demonstrated in an extensiv...

Prometheus Licenses COLAL-PRED(R) From Alizyme

...-104 for mucositis, a side effect of cancer therapy. COLAL-PRED is the combination of Alizyme's proprietary colonic drug delivery system, COLAL, and prednisolone metasulfobenzoate sodium ("PMSBS"), an approved steroid in Europe. COLAL-PRED has a starch coating that is only broken down in the gut by bacteria occ...

Screening of Corticosteroids in Urine by Negative Atmospheric Pressure Chemical Ionization LC/MS/MS

...thod specific for the suspected corticosteroid monitoring at least three of its MS/MS transitions. Particular care was taken to separate the prednisolone from cortisone. The two corticosteroids have the same molecular masses, and cortisone gives an abundant peak on the transition (-) 419.2>329 of predni...

Performance of Ad-A-Gene EGFP-Glucocorticoid Receptor (EGFP-GCCR): an adenoviral vector gene delivery system

...-mM stock in ethanol; β-estradiol, RU486, progesterone, and prednisolone (Sigma). Stocks in ethanol or DMSO at suitable concentrations. ...tency of dexamethasone (mean nucleus to cytoplasm ratio 6.33, SD 1.154) and prednisolone (mean 6.79, SD 0.938) at the GCCR. The high response to RU486 (mean 4.05, S...
Prednisolone in Biological Definition

Muscle

... condition that mainly occurs in the elderly; it is associated with giant-cell arteritis . It often responds dramatically to glucocorticoids (e.g. prednisolone ). Polymyositis , dermatomyositis and inclusion-body myositis are autoimmune conditions in which the muscle is affected. Rhabdomyolysis ...
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