New drug shows promise as powerful anticancer agent
Research published in the March issue of the journal Cancer Cell describes a small molecule inhibitor of polo-like kinase1 (Plk1) that could lead to a new avenue for targeted cancer therapy. The compound, ON01910, is a potent inhibitor of human tumors in a mouse model system and has low toxicity. The results of this study have led to clinical evaluation of this compound in phase I clinical trials...Mosaic mouse technique offers a powerful new tool to study diseases and genetics
A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice. Writing in the May 6 edition of the journal Cell, researchers from Stanford University describe a streamlined method for creating a "genetic mosaic mouse"--a rodent whose body is genetically engineered to produce small clusters of cells w...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
They're but a tiny speck, existing in a variety of forms: particles, tubes, shells, even a soccerball-like shape. They also share a common prefix: "nano," connoting their size, a billionth of a meter or roughly 25-millionth of an inch. Today, cancer researchers are exploring the potential of such nanostructures to exquisitely target cancer cells without harming surrounding tissue, and to...'License to kill' enables powerful immune attack cells in mice
Scientists have discovered that a group of important immune system cells has a surprising resemblance to cinematic British superspy James Bond: the cells receive a "license" that allows them to unleash their most potent attacks on enemies. This licensing process apparently helps reduce the chances that the cells will erroneously direct their firepower at the body's own tissues, according t...Powerful new tool for studying brain development
Scientists at St. Jude Children's Research Hospital have given investigators around the world free access to a powerful tool for studying brain development. The Internet-based tool, called the mouse Brain Gene Expression Map (BGEM), is one of the largest gene expression maps of an organ ever developed, according to the St. Jude researchers. They say the map will likely help scientists discover th...ChromQuest is a powerful and flexible Chromatography Data System (CDS) from Thermo Scientific
Description:Thermo Scientific ChromQuest Chromatography Data System (CDS) now provides integrated instrument control, digital data acquisition, chromatography data processing and reporting for the Thermo Scientific Accela High Speed LC. The companys innovative HPLC instrument has been designed to maximize the benefits of Thermo Scientific Hypersil GOLD 1.9 m column particle technology and enables LC and LC/M...Temporal Temperature Gradient Electrophoresis: A Powerful Technique to Screen Mutations
Bio-Rad Laboratories, Paul Zoller, Theresa Redila-Flores, Dan Chu, andAsmita Patel, Ph.D. As the number of diseases and disorders linked to gene mutations grow, the need for scanning single-base mutations becomes ever more vital to extending understanding of disease-risk predictor mutations and their...SNPs Powerful Tools for Association Studies
Physical differences between individuals have a strong genetic compon...Mushroom found to contain powerful antibiotic
Scientists at the Danish biotechnology company have now isolated a compound from a class of small black mushroom found in the woods of northern Europe. The newly discovered compound has been derived from a class of fungi called Pseudoplectania// nigrella and is believed to be as effective as penicillin. Plectasin, a peptide derived from the fungus, is found to be as effective as penicil...Direct To Home: Television Provides Powerful Fillip to Smoking Cessation Campaigns.
American Journal of Preventive Medicine has weighed the impact of advertisements that carry an anti-smoking message, with other types of cessation help -nicotine // replacement therapy (NRT), prescribed medications, professional help or advice, self-help materials, cessation programs, telephone quit line, or web-based cessation sites. The study has revealed that television advertisement...Figment of Imagination? A Powerful US Economy Gives Rise to Fatal Heart Attacks
Have you ever heard of a well-fed economy as a potential heart attack risk? According to a recent study, the risk of dying// of a heart attack gets elevated with the strengthening of the US economy. Christopher Ruhm, an economics professor at the University of North Carolina at Greensboro wrote in his study that there is a pronounced increase in death rate due to heart attacks, when th...Powerful Synergy: Botswana and Clinton foundation To Sign MOU
Gaborone – Furthering the initiative to improve HIV/AIDS treatment and evolve better prevention strategies, The Clinton HIV/AIDS Foundation and Botswana Government will// get into an agreement this month, to formally seal their synergy and take forward the vision, of an AIDS free nation. It is well known that, The Clinton Foundation has been a trailblazer of sorts, aiming ceaselessly to eliminate...G 4.12 Powerful Ventilated Floor-Standing Centrifuge
Description:Powerful ventilated floor-standing centrifuge. Mobile space saver, very powerful, high capacity rotors, large choice of accessories, analog controls, large bright digital display, imbalance detection & shutdown (JOUAN patented pendulum system), guard barrier, dual lid interlock, current and temperature limitation, rugged motor, tough steel casing with chemical-resistant, baked-on epoxy coating, C...CR 4.12 Powerful Refrigerated Bench-Top Centrifuge.
Description:Powerful refrigerated bench-top centrifuge. Very powerful, high capacity rotors, large choice of accessories, heat labile sample protection, guard barrier, dual lid interlock, easy to use, variable control, safe, reliable, CE marked....CR 4.22 Powerful Programmable Refrigerated Bench-Top Centrifuge.
Description:Powerful programmable refrigerated bench-top centrifuge. Very powerful, high capacity rotors, large choice of accessories, heat labile sample protection, true sample temperature control, microprocessor control, lifetime reproducibility, true RCF, informative display, versatile, safe, reliable, CE marked....GR 4.12 Powerful Refrigerated Floor-Standing Centrifuge.
Description:Powerful refrigerated floor-standing centrifuge. Mobile space saver, very powerful, high capacity rotors, large choice of accessories, analog controls, large bright digital display, imbalance detection & shutdown (JOUAN patented pendulum system), guard barrier, dual lid interlock, current and temperature limitation, rugged motor, tough steel casing with chemical-resistant, baked-on epoxy coating,...GR 4.22 Powerful Programmable Refrigerated Floor-standing Centrifuge.
Description:Powerful programmable refrigerated floor-standing centrifuge. Mobile space saver, very powerful, high capacity rotors, large choice of accessories, microprocessor control, lifetime reproducibility, informative display, display in 4 languages, imbalance detection & shutdown (JOUAN patented pendulum system), guard barrier, dual lid interlock, current and temperature limitation, rugged motor, tough...